Adaptimmune Therapeutics PLC is focused on pre-clinical programs, including PRAME and CD70-directed T-cell therapies, and its allogeneic pipeline. PRAME is highly expressed across a range of solid tumors, including ovarian, endometrial, lung and breast cancers. The CD70 program targets the CD70 antigen, which is expressed across a range of hematological malignancies (acute myeloid leukemia and lymphoma) and solid tumors (renal cell carcinoma). It is using TRuC technology to develop a T-cell therapy (ADP-520) against CD70, with membrane bound IL-15 to enhance persistence. ADP-520 is in pre-clinical testing. TRuC technology combines the targeting of CAR-T cells with T-cell TCR signaling.
公司代碼ADAP
公司名稱Adaptimmune Therapeutics PLC
上市日期May 06, 2015
CEORawcliffe (Adrian George)
員工數量506
證券類型Depository Receipt
年結日May 06
公司地址60 Jubilee Avenue
城市ABINGDON
上市交易所NASDAQ Capital Market Consolidated
國家United Kingdom
郵編OX14 4RX
電話441235430000
網址https://www.adaptimmune.com/
公司代碼ADAP
上市日期May 06, 2015
CEORawcliffe (Adrian George)