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Silence Therapeutics PLC

SLN
6.450USD
+0.080+1.26%
收盘 12/22, 16:00美东报价延迟15分钟
304.66M总市值
亏损市盈率 TTM

Silence Therapeutics PLC

6.450
+0.080+1.26%

关于 Silence Therapeutics PLC 公司

Silence Therapeutics plc is a global clinical-stage biotechnology company engaged in transforming people’s lives by silencing diseases through precision-engineered medicines created with proprietary siRNA (short interfering RNA) technology. The Company leverages its mRNAi GOLD platform to create siRNAs designed to precisely target and silence disease-associated genes in the liver. The Company focuses on areas of high unmet medical need with programs advancing cardiovascular disease, hematology and rare diseases. Divesiran (SLN124) is its wholly owned siRNA product candidate designed to inhibit TMPRSS6 expression in the liver. Zerlasiran is a siRNA molecule designed for the treatment of cardiovascular disease associated with elevated Lp(a), a lipoprotein in the blood. In addition to its wholly owned clinical pipeline, it has a third siRNA product candidate from its mRNAi GOLD platform in Phase I development in an undisclosed indication through its collaboration with AstraZeneca.

Silence Therapeutics PLC简介

公司代码SLN
公司名称Silence Therapeutics PLC
上市日期Jan 05, 2010
CEOTooman (Craig A)
员工数量116
证券类型Depository Receipt
年结日Jan 05
公司地址72 Hammersmith Road
城市LONDON
上市交易所NASDAQ OMX - NASDAQ BASIC
国家United Kingdom
邮编W14 8TH
电话442034576900
网址https://www.silence-therapeutics.com/
公司代码SLN
上市日期Jan 05, 2010
CEOTooman (Craig A)

Silence Therapeutics PLC公司高管

名称
名称/职务
职务
持股
持股变动
Mr. Timothy (Tim) McInerney
Mr. Timothy (Tim) McInerney
Independent Director
Independent Director
--
--
Mr. Craig A. Tooman
Mr. Craig A. Tooman
President, Chief Executive Officer, Executive Director
President, Chief Executive Officer, Executive Director
--
--
Dr. Steven J. Romano, M.D.
Dr. Steven J. Romano, M.D.
Executive Vice President, Chief of Research and Development Officer
Executive Vice President, Chief of Research and Development Officer
--
--
Ms. Rhonda Heliums
Ms. Rhonda Heliums
Chief Financial Officer, Executive Vice President
Chief Financial Officer, Executive Vice President
--
--
Mr. Iain Gladstone Ross
Mr. Iain Gladstone Ross
Non-Executive Independent Chairman of the Board
Non-Executive Independent Chairman of the Board
--
--
Mr. David Jakob (Dave) Lemus, CPA
Mr. David Jakob (Dave) Lemus, CPA
Non-Executive Independent Director
Non-Executive Independent Director
--
--
Ms. Gem Hopkins
Ms. Gem Hopkins
Head of IR and Corporate Communications
Head of IR and Corporate Communications
--
--
名称
名称/职务
职务
持股
持股变动
Mr. Timothy (Tim) McInerney
Mr. Timothy (Tim) McInerney
Independent Director
Independent Director
--
--
Mr. Craig A. Tooman
Mr. Craig A. Tooman
President, Chief Executive Officer, Executive Director
President, Chief Executive Officer, Executive Director
--
--
Dr. Steven J. Romano, M.D.
Dr. Steven J. Romano, M.D.
Executive Vice President, Chief of Research and Development Officer
Executive Vice President, Chief of Research and Development Officer
--
--
Ms. Rhonda Heliums
Ms. Rhonda Heliums
Chief Financial Officer, Executive Vice President
Chief Financial Officer, Executive Vice President
--
--
Mr. Iain Gladstone Ross
Mr. Iain Gladstone Ross
Non-Executive Independent Chairman of the Board
Non-Executive Independent Chairman of the Board
--
--
Mr. David Jakob (Dave) Lemus, CPA
Mr. David Jakob (Dave) Lemus, CPA
Non-Executive Independent Director
Non-Executive Independent Director
--
--

收入明细

单位: USD更新时间: 10月6日 周一
单位: USD更新时间: 10月6日 周一
FY2024
FY2024Q3
FY2024Q2
FY2024Q1
FY2023Q3
FY2023Q2
FY2023Q1
由于公司未披露,未能获取相关数据
地区USD
名称
营收
占比
United Kingdom
43.11M
99.67%
Germany
144.00K
0.33%
USA
0.00
0.00%
业务
地区
由于公司未披露,未能获取相关数据

股东统计

更新时间: 11月16日 周日
更新时间: 11月16日 周日
持股股东
股东类型
持股股东
持股股东
占比
Griffiths (Richard Ian)
24.38%
TCG Crossover Management, LLC
6.42%
Invus Public Equities Advisors, LLC
6.16%
Redmile Group, LLC
4.58%
Lombard Odier Asset Management (USA) Corp.
3.91%
其他
54.55%
持股股东
持股股东
占比
Griffiths (Richard Ian)
24.38%
TCG Crossover Management, LLC
6.42%
Invus Public Equities Advisors, LLC
6.16%
Redmile Group, LLC
4.58%
Lombard Odier Asset Management (USA) Corp.
3.91%
其他
54.55%
股东类型
持股股东
占比
Individual Investor
24.38%
Investment Advisor
18.46%
Investment Advisor/Hedge Fund
9.97%
Venture Capital
3.35%
Hedge Fund
3.30%
Research Firm
3.11%
Private Equity
2.05%
Bank and Trust
0.03%
其他
35.34%

机构持股

更新时间: 10月1日 周三
更新时间: 10月1日 周三
报告期
机构数
持股数
持股占比
持股变动
2025Q3
138
19.95M
42.23%
-14.76M
2025Q2
131
33.68M
71.31%
-14.18M
2025Q1
133
31.94M
67.63%
-14.00M
2024Q4
128
31.43M
66.56%
-10.23M
2024Q3
111
35.93M
77.05%
-5.19M
2024Q2
96
34.94M
74.95%
-4.57M
2024Q1
86
35.43M
76.18%
+4.14M
2023Q4
61
30.21M
78.15%
-609.51K
2023Q3
58
32.62M
88.08%
+1.55M
2023Q2
54
31.78M
89.08%
+2.79M
查看更多

股东持股明细

名称
持股数
占比
持股变动
变动比例
公告日期
Griffiths (Richard Ian)
11.51M
24.38%
+543.58K
+4.95%
Jun 25, 2025
TCG Crossover Management, LLC
3.03M
6.42%
--
--
Jun 30, 2025
Invus Public Equities Advisors, LLC
2.91M
6.16%
+121.61K
+4.36%
Jun 30, 2025
Redmile Group, LLC
2.16M
4.58%
-50.17K
-2.27%
Jun 30, 2025
Lombard Odier Asset Management (USA) Corp.
1.85M
3.92%
--
--
Jun 30, 2025
Morgan Stanley & Co. LLC
1.13M
2.39%
-766.91K
-40.44%
Jun 30, 2025
Vivo Capital, LLC
1.11M
2.34%
--
--
Jun 30, 2025
Nantahala Capital Management, LLC
1.04M
2.21%
--
--
Jun 30, 2025
Frazier Life Sciences Management, L.P.
970.13K
2.05%
-178.46K
-15.54%
Jun 30, 2025
Nextech Invest, Ltd.
952.40K
2.02%
--
--
Jun 30, 2025
查看更多

持股ETF

更新时间: 12月2日 周二
更新时间: 12月2日 周二
机构名称
占比
Virtus LifeSci Biotech Clinical Trials ETF
0.87%
ProShares Ultra Nasdaq Biotechnology
0.03%
Invesco Nasdaq Biotechnology ETF
0.03%
SPDR S&P International Small Cap ETF
0.01%
ActivePassive International Equity ETF
0%
iShares Biotechnology ETF
0%
Tema Heart & Health ETF
0%
Virtus LifeSci Biotech Clinical Trials ETF
占比0.87%
ProShares Ultra Nasdaq Biotechnology
占比0.03%
Invesco Nasdaq Biotechnology ETF
占比0.03%
SPDR S&P International Small Cap ETF
占比0.01%
ActivePassive International Equity ETF
占比0%
iShares Biotechnology ETF
占比0%
Tema Heart & Health ETF
占比0%

分红派息

近5年累计派现 0.00 美元
公告日期
分红计划
股权登记日
现金发放日
除权除息日
暂无数据

拆合股

公告日期
类型
比率
暂无数据
公告日期
类型
比率
暂无数据

常见问题

Silence Therapeutics PLC的前五大股东是谁?

Silence Therapeutics PLC 的前五大股东如下:
Griffiths (Richard Ian)持有股份:11.51M,占总股份比例:24.38%。
TCG Crossover Management, LLC持有股份:3.03M,占总股份比例:6.42%。
Invus Public Equities Advisors, LLC持有股份:2.91M,占总股份比例:6.16%。
Redmile Group, LLC持有股份:2.16M,占总股份比例:4.58%。
Lombard Odier Asset Management (USA) Corp.持有股份:1.85M,占总股份比例:3.92%。

Silence Therapeutics PLC的前三大股东类型是什么?

Silence Therapeutics PLC 的前三大股东类型分别是:
Griffiths (Richard Ian)
TCG Crossover Management, LLC
Invus Public Equities Advisors, LLC

有多少机构持有Silence Therapeutics PLC(SLN)的股份?

截至2025Q3,共有138家机构持有Silence Therapeutics PLC的股份,合计持有的股份价值约为19.95M,占公司总股份的42.23%。与2025Q2相比,机构持股有所增加,增幅为-29.08%。

哪个业务部门对Silence Therapeutics PLC的收入贡献最大?

在FY2024,--业务部门对Silence Therapeutics PLC的收入贡献最大,创收--,占总收入的--%。
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