Karyopharm Therapeutics Inc
KPTI5.360USD
-0.290-5.13%
收盘 11/05, 16:00（美东）报价延迟15分钟
46.64M总市值
亏损市盈率 TTM
关于 Karyopharm Therapeutics Inc 公司
Karyopharm Therapeutics Inc. 是一家商业阶段制药公司。该公司致力于发现、开发和商业化针对核输出的药物，用于治疗癌症和其他疾病。该公司正在开发和商业化小分子选择性核输出抑制剂 (SINE) 化合物，该化合物可抑制核输出蛋白输出蛋白 1 (XPO1)。其主要资产 XPOVIO (selinexor) 与硼替佐米和地塞米松联合用于治疗已接受过至少一种先前治疗的多发性骨髓瘤成人患者。该公司正在评估 selinexor 在某些血液和实体肿瘤恶性肿瘤中的应用，包括多发性骨髓瘤、子宫内膜癌、蕈样肉芽肿 (MF) 和弥漫性大 B 细胞淋巴瘤 (DLBCL)。该公司的候选产品 eltanexor 是一种口服 SINE 化合物，与 selinexor 一样，可选择性阻断核输出蛋白 XPO1。
Karyopharm Therapeutics Inc简介
公司代码KPTI
公司名称Karyopharm Therapeutics Inc
上市日期Nov 06, 2013
CEOMr. Richard A. Paulson
员工数量279
证券类型Ordinary Share
年结日Nov 06
公司地址85 Wells Avenue
城市NEWTON
上市交易所NASDAQ Global Select Consolidated
国家United States of America
邮编02459
电话16176580600
网址https://karyopharm.com/
公司代码KPTI
上市日期Nov 06, 2013
CEOMr. Richard A. Paulson
Karyopharm Therapeutics Inc公司高管
名称
名称/职务
职务
持股
持股变动
Mr. Michael Mano, J.D.
Mr. Michael Mano, J.D.
Senior Vice President, General Counsel, Secretary
Senior Vice President, General Counsel, Secretary
55.93K
+355.57%
Mr. Stuart Poulton
Mr. Stuart Poulton
Executive Vice President, Chief Development Officer
Executive Vice President, Chief Development Officer
48.29K
+460.88%
Dr. Reshma Rangwala, M.D., Ph.D.
Dr. Reshma Rangwala, M.D., Ph.D.
Executive Vice President, Chief Medical Officer
Executive Vice President, Chief Medical Officer
7.24K
+8.01%
Mr. Barry E. Greene
Mr. Barry E. Greene
Lead Independent Director
Lead Independent Director
907.00
--
Ms. Sohanya Cheng
Ms. Sohanya Cheng
Executive Vice President, Chief Commercial Officer
Executive Vice President, Chief Commercial Officer
--
--
Mr. Garen G. Bohlin
Mr. Garen G. Bohlin
Independent Director
Independent Director
--
--
Mr. Chen Schor, CPA
Mr. Chen Schor, CPA
Independent Director
Independent Director
--
--
Mr. Richard A. Paulson
Mr. Richard A. Paulson
President, Chief Executive Officer, Director
President, Chief Executive Officer, Director
--
--
Mr. Brendan Strong
Mr. Brendan Strong
Senior Vice President - Investor Relations and Corporate Communications
Senior Vice President - Investor Relations and Corporate Communications
--
--
Ms. Lori Macomber, CPA
Ms. Lori Macomber, CPA
Executive Vice President, Chief Financial Officer, Treasurer
Executive Vice President, Chief Financial Officer, Treasurer
--
--
查看更多
名称
名称/职务
职务
持股
持股变动
Mr. Michael Mano, J.D.
Mr. Michael Mano, J.D.
Senior Vice President, General Counsel, Secretary
Senior Vice President, General Counsel, Secretary
55.93K
+355.57%
Mr. Stuart Poulton
Mr. Stuart Poulton
Executive Vice President, Chief Development Officer
Executive Vice President, Chief Development Officer
48.29K
+460.88%
Dr. Reshma Rangwala, M.D., Ph.D.
Dr. Reshma Rangwala, M.D., Ph.D.
Executive Vice President, Chief Medical Officer
Executive Vice President, Chief Medical Officer
7.24K
+8.01%
Mr. Barry E. Greene
Mr. Barry E. Greene
Lead Independent Director
Lead Independent Director
907.00
--
Ms. Sohanya Cheng
Ms. Sohanya Cheng
Executive Vice President, Chief Commercial Officer
Executive Vice President, Chief Commercial Officer
--
--
Mr. Garen G. Bohlin
Mr. Garen G. Bohlin
Independent Director
Independent Director
--
--
收入明细
暂无数据
暂无数据
业务
地区
暂无数据
股东统计
更新时间: 11月1日 周六
更新时间: 11月1日 周六
持股股东
股东类型
持股股东
持股股东
占比
Opaleye Management Inc.
5.57%
J. Wood Capital Advisors LLC
4.60%
T. Rowe Price Investment Management, Inc.
4.27%
J.P. Morgan Securities LLC
2.51%
Adage Capital Management, L.P.
2.47%
其他
80.57%
持股股东
持股股东
占比
Opaleye Management Inc.
5.57%
J. Wood Capital Advisors LLC
4.60%
T. Rowe Price Investment Management, Inc.
4.27%
J.P. Morgan Securities LLC
2.51%
Adage Capital Management, L.P.
2.47%
其他
80.57%
股东类型
持股股东
占比
Hedge Fund
14.86%
Investment Advisor
10.63%
Research Firm
5.50%
Investment Advisor/Hedge Fund
3.08%
Corporation
2.88%
Individual Investor
2.49%
Venture Capital
1.00%
Bank and Trust
0.01%
其他
59.55%
机构持股
更新时间: 10月1日 周三
更新时间: 10月1日 周三
报告期
机构数
持股数
持股占比
持股变动
2025Q3
250
4.64M
29.19%
-677.45K
2025Q2
284
4.20M
48.66%
-1.75M
2025Q1
308
4.25M
49.43%
-1.53M
2024Q4
324
4.68M
55.67%
-1.51M
2024Q3
341
4.98M
60.06%
-2.16M
2024Q2
356
5.56M
67.54%
-2.08M
2024Q1
352
5.60M
72.46%
-1.99M
2023Q4
354
5.60M
73.31%
-2.02M
2023Q3
365
5.88M
77.33%
-1.69M
2023Q2
380
6.19M
81.48%
-2.04M
查看更多
股东持股明细
名称
持股数
占比
持股变动
变动比例
公告日期
J. Wood Capital Advisors LLC
458.13K
5.28%
--
--
Apr 10, 2025
T. Rowe Price Investment Management, Inc.
728.77K
8.4%
+589.12K
+421.87%
Jun 30, 2025
J.P. Morgan Securities LLC
256.44K
2.96%
+109.02K
+73.95%
Jun 30, 2025
Adage Capital Management, L.P.
421.32K
4.86%
--
--
Jun 30, 2025
The Vanguard Group, Inc.
518.27K
5.98%
+7.97K
+1.56%
Jun 30, 2025
Eversept Partners, LP
257.15K
2.97%
--
--
Jun 30, 2025
Citadel Advisors LLC
206.78K
2.38%
-128.00
-0.06%
Jun 30, 2025
Palo Alto Investors LP
187.91K
2.17%
-136.12K
-42.01%
Jun 30, 2025
BlackRock Institutional Trust Company, N.A.
184.85K
2.13%
-3.16K
-1.68%
Jun 30, 2025
查看更多
持股ETF
更新时间: 11月2日 周日
更新时间: 11月2日 周日
机构名称
占比
iShares Micro-Cap ETF
0.01%
Global X Russell 2000 Covered Call ETF
0%
Invesco NASDAQ Future Gen 200 ETF
0%
Fidelity Enhanced Small Cap ETF
0%
Goldman Sachs ActiveBeta US Small Cap Equity ETF
0%
ProShares Hedge Replication ETF
0%
iShares Russell 2000 ETF
0%
ProShares UltraPro Russell2000
0%
Proshares Ultra Russell 2000
0%
iShares Russell 2000 Growth ETF
0%
查看更多
iShares Micro-Cap ETF
占比0.01%
Global X Russell 2000 Covered Call ETF
占比0%
Invesco NASDAQ Future Gen 200 ETF
占比0%
Fidelity Enhanced Small Cap ETF
占比0%
Goldman Sachs ActiveBeta US Small Cap Equity ETF
占比0%
ProShares Hedge Replication ETF
占比0%
iShares Russell 2000 ETF
占比0%
ProShares UltraPro Russell2000
占比0%
Proshares Ultra Russell 2000
占比0%
iShares Russell 2000 Growth ETF
占比0%
分红派息
近5年累计派现
0.00
美元
公告日期
分红计划
股权登记日
现金发放日
除权除息日
暂无数据
拆合股
公告日期
类型
比率
Feb 24, 2025
Merger
15→1
Feb 24, 2025
Merger
15→1
Feb 24, 2025
Merger
15→1
Feb 24, 2025
Merger
15→1
公告日期
类型
比率
Feb 24, 2025
Merger
15→1
Feb 24, 2025
Merger
15→1
Feb 24, 2025
Merger
15→1
Feb 24, 2025
Merger
15→1
