Karyopharm Therapeutics Inc
KPTI5.360USD
-0.290-5.13%
Fechamento 11/05, 16:00（ET）Cotações atrasadas em 15 min
46.64MValor de mercado
PerdaP/L TTM
Mais detalhes de Karyopharm Therapeutics Inc Empresa
Karyopharm Therapeutics Inc. is a commercial-stage pharmaceutical company. The Company is engaged in the discovery, development and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. It is developing and commercializing small molecule Selective Inhibitor of Nuclear Export (SINE) compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead asset, XPOVIO (selinexor), is marketed in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy. The Company is engaged in evaluating selinexor in certain hematological and solid tumor malignancies, including multiple myeloma, endometrial cancer, mycosis fungoides (MF) and diffuse large B-cell lymphoma (DLBCL). The Company’s product candidate, eltanexor, oral SINE compound that, like selinexor, selectively blocks the nuclear export protein XPO1.
Informações de Karyopharm Therapeutics Inc
Código da empresaKPTI
Nome da EmpresaKaryopharm Therapeutics Inc
Data de listagemNov 06, 2013
CEOMr. Richard A. Paulson
Número de funcionários279
Tipo de títulosOrdinary Share
Fim do ano fiscalNov 06
Endereço85 Wells Avenue
CidadeNEWTON
Bolsa de valoresNASDAQ Global Select Consolidated
PaísUnited States of America
Código postal02459
Telefone16176580600
Sitehttps://karyopharm.com/
Código da empresaKPTI
Data de listagemNov 06, 2013
CEOMr. Richard A. Paulson
Executivos da empresa Karyopharm Therapeutics Inc
Nome
Nome/Posição
Posição
Ações detidas
Variação
Mr. Michael Mano, J.D.
Mr. Michael Mano, J.D.
Senior Vice President, General Counsel, Secretary
Senior Vice President, General Counsel, Secretary
55.93K
+355.57%
Mr. Stuart Poulton
Mr. Stuart Poulton
Executive Vice President, Chief Development Officer
Executive Vice President, Chief Development Officer
48.29K
+460.88%
Dr. Reshma Rangwala, M.D., Ph.D.
Dr. Reshma Rangwala, M.D., Ph.D.
Executive Vice President, Chief Medical Officer
Executive Vice President, Chief Medical Officer
7.24K
+8.01%
Mr. Barry E. Greene
Mr. Barry E. Greene
Lead Independent Director
Lead Independent Director
907.00
--
Ms. Sohanya Cheng
Ms. Sohanya Cheng
Executive Vice President, Chief Commercial Officer
Executive Vice President, Chief Commercial Officer
--
--
Mr. Garen G. Bohlin
Mr. Garen G. Bohlin
Independent Director
Independent Director
--
--
Mr. Chen Schor, CPA
Mr. Chen Schor, CPA
Independent Director
Independent Director
--
--
Mr. Richard A. Paulson
Mr. Richard A. Paulson
President, Chief Executive Officer, Director
President, Chief Executive Officer, Director
--
--
Mr. Brendan Strong
Mr. Brendan Strong
Senior Vice President - Investor Relations and Corporate Communications
Senior Vice President - Investor Relations and Corporate Communications
--
--
Ms. Lori Macomber, CPA
Ms. Lori Macomber, CPA
Executive Vice President, Chief Financial Officer, Treasurer
Executive Vice President, Chief Financial Officer, Treasurer
--
--
Ver Mais
Nome
Nome/Posição
Posição
Ações detidas
Variação
Mr. Michael Mano, J.D.
Mr. Michael Mano, J.D.
Senior Vice President, General Counsel, Secretary
Senior Vice President, General Counsel, Secretary
55.93K
+355.57%
Mr. Stuart Poulton
Mr. Stuart Poulton
Executive Vice President, Chief Development Officer
Executive Vice President, Chief Development Officer
48.29K
+460.88%
Dr. Reshma Rangwala, M.D., Ph.D.
Dr. Reshma Rangwala, M.D., Ph.D.
Executive Vice President, Chief Medical Officer
Executive Vice President, Chief Medical Officer
7.24K
+8.01%
Mr. Barry E. Greene
Mr. Barry E. Greene
Lead Independent Director
Lead Independent Director
907.00
--
Ms. Sohanya Cheng
Ms. Sohanya Cheng
Executive Vice President, Chief Commercial Officer
Executive Vice President, Chief Commercial Officer
--
--
Mr. Garen G. Bohlin
Mr. Garen G. Bohlin
Independent Director
Independent Director
--
--
Detalhamento da receita
Sem dados
Sem dados
Por Empresa
Por Região
Sem dados
Distribuição de ações
Atualizado em: sáb, 1 de nov
Atualizado em: sáb, 1 de nov
Investidores
Tipos de investidores
Investidores
Investidores
Proporção
Opaleye Management Inc.
5.57%
J. Wood Capital Advisors LLC
4.60%
T. Rowe Price Investment Management, Inc.
4.27%
J.P. Morgan Securities LLC
2.51%
Adage Capital Management, L.P.
2.47%
Outro
80.57%
Investidores
Investidores
Proporção
Opaleye Management Inc.
5.57%
J. Wood Capital Advisors LLC
4.60%
T. Rowe Price Investment Management, Inc.
4.27%
J.P. Morgan Securities LLC
2.51%
Adage Capital Management, L.P.
2.47%
Outro
80.57%
Tipos de investidores
Investidores
Proporção
Hedge Fund
14.86%
Investment Advisor
10.63%
Research Firm
5.50%
Investment Advisor/Hedge Fund
3.08%
Corporation
2.88%
Individual Investor
2.49%
Venture Capital
1.00%
Bank and Trust
0.01%
Outro
59.55%
Participação acionária institucional
Atualizado em: qua, 1 de out
Atualizado em: qua, 1 de out
Período do relatório
N.º de instituições
Ações detidas
Proporção
Variação
2025Q3
250
4.64M
29.19%
-677.45K
2025Q2
284
4.20M
48.66%
-1.75M
2025Q1
308
4.25M
49.43%
-1.53M
2024Q4
324
4.68M
55.67%
-1.51M
2024Q3
341
4.98M
60.06%
-2.16M
2024Q2
356
5.56M
67.54%
-2.08M
2024Q1
352
5.60M
72.46%
-1.99M
2023Q4
354
5.60M
73.31%
-2.02M
2023Q3
365
5.88M
77.33%
-1.69M
2023Q2
380
6.19M
81.48%
-2.04M
Ver Mais
Atividade dos acionistas
Nome
Ações detidas
Proporção
Variação
Var. %
Data
J. Wood Capital Advisors LLC
458.13K
5.28%
--
--
Apr 10, 2025
T. Rowe Price Investment Management, Inc.
728.77K
8.4%
+589.12K
+421.87%
Jun 30, 2025
J.P. Morgan Securities LLC
256.44K
2.96%
+109.02K
+73.95%
Jun 30, 2025
Adage Capital Management, L.P.
421.32K
4.86%
--
--
Jun 30, 2025
The Vanguard Group, Inc.
518.27K
5.98%
+7.97K
+1.56%
Jun 30, 2025
Eversept Partners, LP
257.15K
2.97%
--
--
Jun 30, 2025
Citadel Advisors LLC
206.78K
2.38%
-128.00
-0.06%
Jun 30, 2025
Palo Alto Investors LP
187.91K
2.17%
-136.12K
-42.01%
Jun 30, 2025
BlackRock Institutional Trust Company, N.A.
184.85K
2.13%
-3.16K
-1.68%
Jun 30, 2025
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Dividendo
Um total de
0.00
USD foi distribuído em dividendos nos últimos 5 anos.
Data
Dividendo
Data de registro
Data de pagamento
Data ex-dividendo
Sem dados
Desdobramento de ações
Data
Tipo
Proporção
Feb 24, 2025
Merger
15→1
Feb 24, 2025
Merger
15→1
Feb 24, 2025
Merger
15→1
Feb 24, 2025
Merger
15→1
Data
Tipo
Proporção
Feb 24, 2025
Merger
15→1
Feb 24, 2025
Merger
15→1
Feb 24, 2025
Merger
15→1
Feb 24, 2025
Merger
15→1
