ASML, a critical supplier of semiconductor manufacturing equipment, particularly EUV lithography systems, is differentiated from chip designers like AMD. While AMD's 2025 stock return exceeded ASML's, ASML demonstrates superior financial performance with higher net sales, gross margin, and operating margin (€32.7 billion vs. $34.6 billion, 52.8% vs. 50%, and 34.6% vs. 10.7% respectively). ASML's strong order backlog (€38.8 billion) and continued R&D investment position it for sustainable growth, driven by AI demand for advanced nodes. Potential risks for ASML include client capital expenditure holds and export restrictions, but its technological moat and market position make it a more robust long-term investment than AMD.

TradingKey - ASML Holding N.V. (NASDAQ: ASML) is not a chip designer; instead, it's best understood as a supplier of equipment for producing semiconductors (sometimes referred to as chips). The company offers hardware, software, and services designed to enable chip makers to create higher performing, more cost-effective, and more energy-efficient microchips; the company's EUV lithography systems are used to print the most sophisticated patterned features onto the latest generations of microchips. ASML's product webpages also convey this image: EUV represents the company's differentiation as a technology, while DUV remains an important technology, and ASML has developed the next generation of High NA lithography systems that will help make 2 nm logic and advanced memory manufacturing possible. In simpler terms, ASML does not compete with end consumers like chip manufacturers; rather, it provides the tools used in creating modern microchips.
The distinction between these two companies is significant given that ASML is very different from its peer company, Advanced Micro Devices, Inc. ("AMD"). ASML makes its money through the sale of lithography systems and related solutions, including refurbished equipment and metrology/inspection. Conversely, AMD is an end-user provider of chips via three reportable divisions: Data Center; Client & Gaming; and Embedded. AMD's Data Center division provides chips for artificial intelligence acceleration, server CPU and GPU and DPU; while its Client division consists of all types of desktop and laptop processors, including chipsets (and hence they compete with other companies in the space), graphics processing units (GPUs), and video console chipsets (so this also includes competition from other companies in that space). Consequently, AMD is much more susceptible to competition through product visibility than ASML is (which with ASML being a critical or primary supplier across the leading-edge manufacturing ecosystem/A3 manufacturing space).
In terms of total return, AMD surpassed ASML during the 2025 calendar year. During the year, AMD achieved a 77.30% total return, while ASML was at 55.84%. The previous statement is an important reminder that momentum in stock prices does not equate to high quality as an investment. AMD's share prices experienced strong performance relative to ASML's share prices because the market is currently paying premium prices for stocks with significant exposure to AI and a much stronger growth narrative for the next 12 months. ASML continued to deliver a strong year; however, the company's stock price was not required to rise as dramatically to support its business case over time.
In ASML's financial results, there is a sizable gap between them and those of AMD for 2025. Total net sales for ASML for 2025 totaled €32.7 billion, with gross margin coming in at 52.8% and income from operations being at €11.3 billion and net income at €9.6 billion. ASML also invested heavily into R&D in 2025, spending €4.7 billion, illustrating that even with significant profits, ASML continues to invest heavily. In contrast, AMD's revenue for 2025 was $34.6 billion with gross margin of 50%, operating income of $3.7 billion and net income of $4.3 billion. When comparing their operating margins to determine how well they convert their sales into profit, ASML provides for approximately 34.6% operating margin on their sales, while AMD converts to approximately 10.7% operating margin on their sales. There is no question that ASML's operating model is much more efficient than AMD's and that it is, therefore, much more sustainable.
Both companies have potential for price increases this coming year, but ASML offers a better investment opportunity based on how it has traded thus far. ASML started the year with an order backlog of €38.8 billion, while they are forecasting revenues for Q1 2026 of between €8.2 billion and €8.9 billion, with a gross margin of between 51% and 53%. According to Reuters, ASML's stock has already increased significantly since December, as they reported strong bookings and customers such as TSMC are expected to increase their capital expenditure. EFN expects ASML’s revenue will grow well above their gross margin, so this will provide ASML with a consistent source of revenue through long replacement cycles and strong demand as AI continues to drive up the requirements for the highest technology nodes and memory devices.
AMD is also developing a good 2026 strategy. The company has provided guidance indicating $9.8 billion (±$300 million) in sales during Q1 2026, which represents growth of around 32% YOY, even though sales would decline sequentially by around 5%. The data centre business achieved record sales of $16.6 billion in 2025, and continues to work on the AI roadmap. However, compared to ASML's disclosures, AMD's filings may provide clearer indication of potential risk; export controls have already created inventory and associated costs, and further change in U.S. policy could limit some of AMD's revenue opportunities, particularly in China. Consequently, while AMD's price may continue to rise, a significant part of the potential upside will depend on continued benchmark execution, and an improvement in the current political environment.
There are risks involved in investing ASML. As ASML is linked directly to semiconductor capital investments, if a client puts a hold on their plans to expand, ASML's business will also slow. Another risk is export restrictions due to continued revisions of semiconductor export rules (e.g., the Netherlands has imposed restrictions on some metrology and inspection equipment in 2025). In conclusion, ASML faces several potential risks; however, the business is also well-protected due to its technological capability, large customer base, significant order backlog, and very important role in the production of leading-edge products. For an investor looking at either ASML or AMD, ASML is the better long-term investment given its moat and overall profitability as well as its sustainability within the value chain of the semiconductor industry. AMD will also generate returns, but ASML will have the most return combined with growth, quality, and sustainability.