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Alnylam Pharmaceuticals Inc

ALNY
449.560USD
-32.030-6.65%
Close 10/30, 16:00ETQuotes delayed by 15 min
58.88BMarket Cap
LossP/E TTM

Alnylam Pharmaceuticals Inc

449.560
-32.030-6.65%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Alnylam Pharmaceuticals Inc

Currency: USD Updated: 2025-10-29

Key Insights

The company's fundamentals are relatively healthy. Its valuation is considered fairly valued,and institutional recognition is very high. Over the past 30 days, multiple analysts have rated the company as a Buy. Despite an average stock market performance, the company shows strong fundamentals and technicals. The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Alnylam Pharmaceuticals Inc's Score

Industry at a Glance

Industry Ranking
15 / 160
Overall Ranking
48 / 4623
Industry
Pharmaceuticals

Support & Resistance

No Data

Score Analysis

Current score
Previous score

Analyst Rating

Based on 30 analysts
Buy
Current Rating
457.164
Target Price
-3.94%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Alnylam Pharmaceuticals Inc Highlights

StrengthsRisks
Alnylam Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. The Company is engaged in discovering, developing, manufacturing and commercializing novel therapeutics based on ribonucleic acid interference (RNAi). Its marketed products include AMVUTTRA (vutrisiran) for the treatment of hereditary transthyretin-mediated amyloidosis (hATTR) with polyneuropathy in adults; ONPATTRO (patisiran) for the treatment of the polyneuropathy of hATTR amyloidosis in adults; GIVLAARI (givosiran) for the treatment of adults with acute hepatic porphyria; OXLUMO (lumasiran) for the treatment of primary hyperoxaluria type 1, and Leqvio (inclisiran), which is being developed and commercialized by its partner, Novartis AG, for the treatment of adults with hypercholesterolemia or mixed dyslipidemia. The Company’s clinical development programs include Cemdisiran, Fitusiran, Zilebesiran, Elebsiran, Mivelsiran and ALN-HTT02. It is developing Cemdisiran to treat complement-mediated diseases.
High Growth
The company's revenue has grown steadily over the past 3 years, averaging 116.72% year-on-year.
Undervalued
The company’s latest PE is -194.60, at a low 3-year percentile range.
Institutional Selling
The latest institutional holdings are 129.94M shares, decreasing 2.49% quarter-over-quarter.
Held by Baillie Gifford
Star Investor Baillie Gifford holds 3.03M shares of this stock.
Higher Market Activity
The company has more investor interest, with a 20-day turnover ratio of 0.39.

Financial Health

Currency: USD Updated: 2025-10-29

The company's current financial score is 7.68, which is lower than the Pharmaceuticals industry's average of 7.76. Its financial status is stable, and its operating efficiency is high. Its latest quarterly revenue reached 773.69M, representing a year-over-year increase of 17.26%, while its net profit experienced a year-over-year increase of 292.43%.

Score

Industry at a Glance

Previous score
7.68
Change
0

Financials

6.08

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
No Data

Quality of Earnings

4.63

Operational Efficiency

10.00

Growth Potential

10.00

Shareholder Returns

7.69

Alnylam Pharmaceuticals Inc's Company Valuation

Currency: USD Updated: 2025-10-29

The company’s current valuation score is 7.42, which is higher than the Pharmaceuticals industry's average of 7.22. Its current P/E ratio is -194.60, which is -100.00% below the recent high of 0.00 and -162.95% above the recent low of -511.69.

Score

Industry at a Glance

Previous score
7.42
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 15/160
No Data

Earnings Forecast

Currency: USD Updated: 2025-10-29

The company’s current earnings forecast score is 7.93, which is higher than the Pharmaceuticals industry's average of 7.79. The average price target for Alnylam Pharmaceuticals Inc is 474.00, with a high of 570.00 and a low of 236.00.

Score

Industry at a Glance

Previous score
7.93
Change
0

Support & Resistance

No Data

Analyst Rating

Based on 30 analysts
Buy
Current Rating
460.779
Target Price
-4.32%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

169
Total
6
Median
8
Average
Company name
Ratings
Analysts
Alnylam Pharmaceuticals Inc
ALNY
30
Biogen Inc
BIIB
36
Amgen Inc
AMGN
34
Vertex Pharmaceuticals Inc
VRTX
33
AbbVie Inc
ABBV
31
Eli Lilly and Co
LLY
31
1
2
3
...
34

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
No Data

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2025-10-29

The company’s current price momentum score is 9.06, which is higher than the Pharmaceuticals industry's average of 6.80. Sideways: Currently, the stock price is trading between the resistance level at 502.70 and the support level at 453.33, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
8.79
Change
0.27

Support & Resistance

No Data

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(5)
Neutral(2)
Buy(0)
Indicators
Value
Direction
MACD(12,26,9)
-3.528
Neutral
RSI(14)
42.577
Neutral
STOCH(KDJ)(9,3,3)
38.359
Sell
ATR(14)
19.112
Low Volatility
CCI(14)
-171.354
Sell
Williams %R
77.899
Sell
TRIX(12,20)
0.158
Sell
StochRSI(14)
0.000
Sell
Moving Average
Sell(4)
Neutral(0)
Buy(2)
Indicators
Value
Direction
MA5
469.814
Sell
MA10
472.486
Sell
MA20
467.327
Sell
MA50
460.598
Sell
MA100
407.097
Buy
MA200
334.953
Buy

Institutional Confidence

Currency: USD Updated: 2025-10-29

The company’s current institutional recognition score is 10.00, which is higher than the Pharmaceuticals industry's average of 5.79. The latest institutional shareholding proportion is 99.13%, representing a quarter-over-quarter decrease of 1.40%. The largest institutional shareholder is The Vanguard, holding a total of 13.24M shares, representing 10.10% of shares outstanding, with 3.00% increase in holdings.

Score

Industry at a Glance

Previous score
10.00
Change
0

Institutional Shareholding

No Data

Shareholder Activity

Name
Shares Held
Chg %
Capital World Investors
16.81M
+0.33%
Fidelity Management & Research Company LLC
15.05M
+2.92%
The Vanguard Group, Inc.
Star Investors
13.24M
+1.83%
Capital Research Global Investors
7.19M
+0.52%
BlackRock Institutional Trust Company, N.A.
6.53M
-2.96%
Regeneron Pharmaceuticals Inc
4.44M
--
T. Rowe Price Investment Management, Inc.
4.28M
-3.10%
3.20M
-4.61%
State Street Investment Management (US)
3.17M
-5.75%
T. Rowe Price Associates, Inc.
Star Investors
3.05M
-10.55%
1
2

Risk Assessment

Currency: USD Updated: 2025-10-29

The company’s current risk assessment score is 8.67, which is higher than the Pharmaceuticals industry's average of 5.13. The company's beta value is 0.30. This indicates that the stock tends to underperform the index during upward trending markets but experiences smaller declines during downward trending markets.

Score

Industry at a Glance

Previous score
8.67
Change
0
Beta vs S&P 500 index
0.30
VaR
+3.61%
240-Day Maximum Drawdown
+22.83%
240-Day Volatility
+41.87%

Return

Best Daily Return
60 days
+5.96%
120 days
+15.43%
5 years
+49.33%
Worst Daily Return
60 days
-3.51%
120 days
-6.58%
5 years
-17.10%
Sharpe Ratio
60 days
+2.37
120 days
+3.27
5 years
+0.68

Risk Assessment

Maximum Drawdown
240 days
+22.83%
3 years
+100.00%
5 years
+100.00%
Return-to-Drawdown Ratio
240 days
+3.46
3 years
+0.35
5 years
+0.36
Skewness
240 days
+0.86
3 years
+3.12
5 years
+4.23

Volatility

Realised Volatility
240 days
+41.87%
5 years
--
Standardised True Range
240 days
+2.34%
5 years
+1.67%
Downside Risk-Adjusted Return
120 days
+663.44%
240 days
+663.44%
Maximum Daily Upside Volatility
60 days
+19.17%
Maximum Daily Downside Volatility
60 days
+16.17%

Liquidity

Average Turnover Rate
60 days
+0.80%
120 days
+0.80%
5 years
--
Turnover Deviation
20 days
+39.27%
60 days
+18.72%
120 days
+19.72%

Peer Comparison

Pharmaceuticals
Alnylam Pharmaceuticals Inc
Alnylam Pharmaceuticals Inc
ALNY
8.30 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Regeneron Pharmaceuticals Inc
Regeneron Pharmaceuticals Inc
REGN
8.83 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Rhythm Pharmaceuticals Inc
Rhythm Pharmaceuticals Inc
RYTM
8.67 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Collegium Pharmaceutical Inc
Collegium Pharmaceutical Inc
COLL
8.57 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Gilead Sciences Inc
Gilead Sciences Inc
GILD
8.56 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Mckesson Corp
Mckesson Corp
MCK
8.52 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
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