Alnylam Pharmaceuticals Inc
ALNY400.590USD
-0.100-0.02%
Close 12/26, 16:00（ET）Quotes delayed by 15 min
52.79BMarket Cap
1233.61P/E TTM
More Details of Alnylam Pharmaceuticals Inc Company
Alnylam Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. The Company is engaged in discovering, developing, manufacturing and commercializing novel therapeutics based on ribonucleic acid interference (RNAi). Its marketed products include AMVUTTRA (vutrisiran) for the treatment of hereditary transthyretin-mediated amyloidosis (hATTR) with polyneuropathy in adults; ONPATTRO (patisiran) for the treatment of the polyneuropathy of hATTR amyloidosis in adults; GIVLAARI (givosiran) for the treatment of adults with acute hepatic porphyria; OXLUMO (lumasiran) for the treatment of primary hyperoxaluria type 1, and Leqvio (inclisiran), which is being developed and commercialized by its partner, Novartis AG, for the treatment of adults with hypercholesterolemia or mixed dyslipidemia. The Company’s clinical development programs include Cemdisiran, Fitusiran, Zilebesiran, Elebsiran, Mivelsiran and ALN-HTT02. It is developing Cemdisiran to treat complement-mediated diseases.
Alnylam Pharmaceuticals Inc Info
Ticker SymbolALNY
Company nameAlnylam Pharmaceuticals Inc
IPO dateMay 28, 2004
CEOGreenstreet (Yvonne L)
Number of employees2230
Security typeOrdinary Share
Fiscal year-endMay 28
Address675 W Kendall St
CityCAMBRIDGE
Stock exchangeNASDAQ OMX - NASDAQ BASIC
CountryUnited States of America
Postal code02142-1168
Phone16175518200
Websitehttps://www.alnylam.com/
Ticker SymbolALNY
IPO dateMay 28, 2004
CEOGreenstreet (Yvonne L)
Company Executives of Alnylam Pharmaceuticals Inc
Name
Name/Position
Position
Shareholding
Change
Dr. Yvonne L. Greenstreet, M.D.
Dr. Yvonne L. Greenstreet, M.D.
Chief Executive Officer, Director
Chief Executive Officer, Director
69.39K
+5.43%
Mr. Jeffrey V. (Jeff) Poulton
Mr. Jeffrey V. (Jeff) Poulton
Chief Financial Officer, Executive Vice President
Chief Financial Officer, Executive Vice President
54.11K
+7.83%
Mr. Tolga Tanguler
Mr. Tolga Tanguler
Chief Commercial Officer
Chief Commercial Officer
27.44K
+5.56%
Dr. Dennis A. Ausiello, M.D.
Dr. Dennis A. Ausiello, M.D.
Independent Director
Independent Director
4.41K
--
Dr. Margaret A. Hamburg, M.D.
Dr. Margaret A. Hamburg, M.D.
Independent Director
Independent Director
911.00
+569.85%
Dr. Olivier Brandicourt, M.D.
Dr. Olivier Brandicourt, M.D.
Independent Director
Independent Director
775.00
--
Mr. Peter N. Kellogg
Mr. Peter N. Kellogg
Independent Director
Independent Director
775.00
--
Ms. Colleen F. Reitan
Ms. Colleen F. Reitan
Independent Director
Independent Director
--
--
Ms. Amy W. Schulman, J.D.
Ms. Amy W. Schulman, J.D.
Independent Chairman of the Board
Independent Chairman of the Board
--
--
Dr. Pushkal P. Garg, M.D.
Dr. Pushkal P. Garg, M.D.
Executive Vice President, Chief Research and Development Officer
Executive Vice President, Chief Research and Development Officer
--
--
View more
Name
Name/Position
Position
Shareholding
Change
Dr. Yvonne L. Greenstreet, M.D.
Dr. Yvonne L. Greenstreet, M.D.
Chief Executive Officer, Director
Chief Executive Officer, Director
69.39K
+5.43%
Mr. Jeffrey V. (Jeff) Poulton
Mr. Jeffrey V. (Jeff) Poulton
Chief Financial Officer, Executive Vice President
Chief Financial Officer, Executive Vice President
54.11K
+7.83%
Mr. Tolga Tanguler
Mr. Tolga Tanguler
Chief Commercial Officer
Chief Commercial Officer
27.44K
+5.56%
Dr. Dennis A. Ausiello, M.D.
Dr. Dennis A. Ausiello, M.D.
Independent Director
Independent Director
4.41K
--
Dr. Margaret A. Hamburg, M.D.
Dr. Margaret A. Hamburg, M.D.
Independent Director
Independent Director
911.00
+569.85%
Dr. Olivier Brandicourt, M.D.
Dr. Olivier Brandicourt, M.D.
Independent Director
Independent Director
775.00
--
Revenue Breakdown
Currency: USDUpdated: Mon, Oct 6
Currency: USDUpdated: Mon, Oct 6
FY2025Q2
FY2025Q1
FY2024
FY2024Q4
FY2024Q3
FY2024Q2
FY2024Q1
FY2023
FY2023Q4
FY2023Q3
FY2023Q2
FY2023Q1
FY2022
FY2022Q4
FY2022Q3
FY2022Q2
FY2022Q1
FY2021
FY2020
By BusinessUSD
Name
Revenue
Proportion
AMVUTTRA
491.95M
63.59%
GIVLAARI
80.85M
10.45%
ONPATTRO
52.54M
6.79%
Other
50.67M
6.55%
OXLUMO
46.87M
6.06%
Other
50.81M
6.57%
By RegionUSD
Name
Revenue
Proportion
United States
454.57M
58.75%
Europe
157.01M
20.29%
Net revenues from collaborations
61.50M
7.95%
Rest of World
60.63M
7.84%
Royalty revenue
39.98M
5.17%
By Business
By Region
By BusinessUSD
Name
Revenue
Proportion
AMVUTTRA
491.95M
63.59%
GIVLAARI
80.85M
10.45%
ONPATTRO
52.54M
6.79%
Other
50.67M
6.55%
OXLUMO
46.87M
6.06%
Other
50.81M
6.57%
Shareholding Stats
Updated: Mon, Nov 17
Updated: Mon, Nov 17
Shareholders
Shareholder Types
Shareholders
Shareholders
Proportion
Capital World Investors
12.44%
Fidelity Management & Research Company LLC
12.04%
The Vanguard Group, Inc.
10.22%
Capital Research Global Investors
5.47%
BlackRock Institutional Trust Company, N.A.
4.98%
Other
54.85%
Shareholders
Shareholders
Proportion
Capital World Investors
12.44%
Fidelity Management & Research Company LLC
12.04%
The Vanguard Group, Inc.
10.22%
Capital Research Global Investors
5.47%
BlackRock Institutional Trust Company, N.A.
4.98%
Other
54.85%
Shareholder Types
Shareholders
Proportion
Investment Advisor
66.37%
Investment Advisor/Hedge Fund
23.04%
Hedge Fund
3.83%
Research Firm
2.50%
Sovereign Wealth Fund
1.70%
Pension Fund
1.29%
Bank and Trust
1.20%
Corporation
1.05%
Individual Investor
0.42%
Institutional Shareholding
Updated: Mon, Dec 8
Updated: Mon, Dec 8
Reporting Period
No. of institutions
Shares Held
Proportion
Change
2025Q4
1441
132.38M
102.07%
-8.88K
2025Q3
1468
132.43M
102.39%
+2.53M
2025Q2
1335
129.81M
101.55%
+2.82M
2025Q1
1292
127.17M
99.72%
-2.77M
2024Q4
1248
125.34M
101.87%
-989.05K
2024Q3
1210
126.51M
99.20%
+3.13M
2024Q2
1165
122.70M
94.98%
+5.27M
2024Q1
1152
117.38M
97.56%
-6.00M
2023Q4
1149
120.10M
100.10%
-712.55K
2023Q3
1103
121.13M
101.32%
-503.11K
View more
Shareholder Activity
Name
Shares Held
Proportion
Change
Chg %
Date
Capital World Investors
16.81M
12.82%
+55.38K
+0.33%
Jun 30, 2025
Fidelity Management & Research Company LLC
15.05M
11.48%
+427.38K
+2.92%
Jun 30, 2025
The Vanguard Group, Inc.
13.24M
10.1%
+238.24K
+1.83%
Jun 30, 2025
Capital Research Global Investors
7.19M
5.49%
+36.93K
+0.52%
Jun 30, 2025
BlackRock Institutional Trust Company, N.A.
6.53M
4.98%
-199.00K
-2.96%
Jun 30, 2025
JP Morgan Asset Management
1.79M
1.37%
-87.08K
-4.64%
Jun 30, 2025
State Street Investment Management (US)
3.17M
2.42%
-193.48K
-5.75%
Jun 30, 2025
Baillie Gifford & Co.
3.03M
2.31%
-625.72K
-17.11%
Jun 30, 2025
Geode Capital Management, L.L.C.
2.40M
1.83%
+75.94K
+3.27%
Jun 30, 2025
Dodge & Cox
3.20M
2.44%
-154.67K
-4.61%
Jun 30, 2025
View more
Related ETFs
Updated: Tue, Dec 2
Updated: Tue, Dec 2
Name
Proportion
Global X Genomics & Biotechnology ETF
6.48%
ProShares Ultra Nasdaq Biotechnology
5.81%
Invesco Nasdaq Biotechnology ETF
5.77%
Franklin Genomic Advancements ETF
5.35%
iShares Biotechnology ETF
5.07%
VanEck Biotech ETF
4.56%
American Century Focused Dynamic Growth ETF
3.76%
Goldman Sachs Future Health Care Equity ETF
3.42%
First Trust NYSE Arca Biotechnology Index Fund
3.33%
Invesco NASDAQ Next Gen 100 ETF
3.28%
View more
Global X Genomics & Biotechnology ETF
Proportion6.48%
ProShares Ultra Nasdaq Biotechnology
Proportion5.81%
Invesco Nasdaq Biotechnology ETF
Proportion5.77%
Franklin Genomic Advancements ETF
Proportion5.35%
iShares Biotechnology ETF
Proportion5.07%
VanEck Biotech ETF
Proportion4.56%
American Century Focused Dynamic Growth ETF
Proportion3.76%
Goldman Sachs Future Health Care Equity ETF
Proportion3.42%
First Trust NYSE Arca Biotechnology Index Fund
Proportion3.33%
Invesco NASDAQ Next Gen 100 ETF
Proportion3.28%
Dividend
A total of
0.00
USD has been distributed in dividends over the past 5 years.
Date
Dividend
Record Date
Payment Date
Ex-dividend Date
No Data
Stock Split
Date
Type
Ratio
No Data
Date
Type
Ratio
No Data
FAQs
Who are the top five shareholders of Alnylam Pharmaceuticals Inc?
The top five shareholders of Alnylam Pharmaceuticals Inc are:
Capital World Investors holds 16.81M shares, accounting for 12.82% of the total shares.
Fidelity Management & Research Company LLC holds 15.05M shares, accounting for 11.48% of the total shares.
The Vanguard Group, Inc. holds 13.24M shares, accounting for 10.10% of the total shares.
Capital Research Global Investors holds 7.19M shares, accounting for 5.49% of the total shares.
BlackRock Institutional Trust Company, N.A. holds 6.53M shares, accounting for 4.98% of the total shares.
Capital World Investors holds 16.81M shares, accounting for 12.82% of the total shares.
Fidelity Management & Research Company LLC holds 15.05M shares, accounting for 11.48% of the total shares.
The Vanguard Group, Inc. holds 13.24M shares, accounting for 10.10% of the total shares.
Capital Research Global Investors holds 7.19M shares, accounting for 5.49% of the total shares.
BlackRock Institutional Trust Company, N.A. holds 6.53M shares, accounting for 4.98% of the total shares.
What are the top three shareholder types of Alnylam Pharmaceuticals Inc?
The top three shareholder types of Alnylam Pharmaceuticals Inc are:
Capital World Investors
Fidelity Management & Research Company LLC
The Vanguard Group, Inc.
Capital World Investors
Fidelity Management & Research Company LLC
The Vanguard Group, Inc.
How many institutions hold shares of Alnylam Pharmaceuticals Inc (ALNY)?
As of 2025Q4, 1441 institutions hold shares of Alnylam Pharmaceuticals Inc, with a combined market value of approximately 132.38M, accounting for 102.07% of the total shares. Compared to 2025Q3, institutional shareholding has increased by -0.32%.
What is the biggest source of revenue for Alnylam Pharmaceuticals Inc?
In FY2025Q2, the AMVUTTRA business generated the highest revenue for Alnylam Pharmaceuticals Inc, amounting to 491.95M and accounting for 63.59% of total revenue.
