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Karyopharm Therapeutics Inc

KPTI
6.940USD
+0.570+8.95%
Cierre 12/19, 16:00ETCotizaciones retrasadas 15 min
60.39MCap. mercado
PérdidaP/E TTM

Karyopharm Therapeutics Inc

6.940
+0.570+8.95%

Más Datos de Karyopharm Therapeutics Inc Compañía

Karyopharm Therapeutics Inc. is a commercial-stage pharmaceutical company. The Company is engaged in the discovery, development and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. It is developing and commercializing small molecule Selective Inhibitor of Nuclear Export (SINE) compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead asset, XPOVIO (selinexor), is marketed in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy. The Company is engaged in evaluating selinexor in certain hematological and solid tumor malignancies, including endometrial cancer, mycosis fungoides (MF) and diffuse large B-cell lymphoma (DLBCL). The Company’s product candidate, eltanexor, is an oral SINE compound like selinexor, that selectively blocks the nuclear export protein XPO1.

Información de Karyopharm Therapeutics Inc

Símbolo de cotizaciónKPTI
Nombre de la empresaKaryopharm Therapeutics Inc
Fecha de salida a bolsaNov 06, 2013
Director ejecutivoPaulson (Richard A)
Número de empleados279
Tipo de seguridadOrdinary Share
Fin del año fiscalNov 06
Dirección85 Wells Avenue
CiudadNEWTON
Bolsa de valoresNASDAQ OMX - NASDAQ BASIC
PaísUnited States of America
Código postal02459
Teléfono16176580600
Sitio Webhttps://karyopharm.com/
Símbolo de cotizaciónKPTI
Fecha de salida a bolsaNov 06, 2013
Director ejecutivoPaulson (Richard A)

Ejecutivos de Karyopharm Therapeutics Inc

Nombre
Nombre/Posición
Posición
Accionistas
Cambio
Mr. Michael Mano, J.D.
Mr. Michael Mano, J.D.
Senior Vice President, General Counsel, Secretary
Senior Vice President, General Counsel, Secretary
55.93K
+355.57%
Mr. Stuart Poulton
Mr. Stuart Poulton
Executive Vice President, Chief Development Officer
Executive Vice President, Chief Development Officer
48.29K
+460.88%
Dr. Reshma Rangwala, M.D., Ph.D.
Dr. Reshma Rangwala, M.D., Ph.D.
Executive Vice President, Chief Medical Officer
Executive Vice President, Chief Medical Officer
7.24K
+8.01%
Mr. Barry E. Greene
Mr. Barry E. Greene
Lead Independent Director
Lead Independent Director
907.00
--
Ms. Sohanya Cheng
Ms. Sohanya Cheng
Executive Vice President, Chief Commercial Officer
Executive Vice President, Chief Commercial Officer
--
--
Mr. Garen G. Bohlin
Mr. Garen G. Bohlin
Independent Director
Independent Director
--
--
Mr. Chen Schor, CPA
Mr. Chen Schor, CPA
Independent Director
Independent Director
--
--
Mr. Richard A. Paulson
Mr. Richard A. Paulson
President, Chief Executive Officer, Director
President, Chief Executive Officer, Director
--
--
Mr. Brendan Strong
Mr. Brendan Strong
Senior Vice President - Investor Relations and Corporate Communications
Senior Vice President - Investor Relations and Corporate Communications
--
--
Ms. Lori Macomber, CPA
Ms. Lori Macomber, CPA
Executive Vice President, Chief Financial Officer, Treasurer
Executive Vice President, Chief Financial Officer, Treasurer
--
--
Ver más
Nombre
Nombre/Posición
Posición
Accionistas
Cambio
Mr. Michael Mano, J.D.
Mr. Michael Mano, J.D.
Senior Vice President, General Counsel, Secretary
Senior Vice President, General Counsel, Secretary
55.93K
+355.57%
Mr. Stuart Poulton
Mr. Stuart Poulton
Executive Vice President, Chief Development Officer
Executive Vice President, Chief Development Officer
48.29K
+460.88%
Dr. Reshma Rangwala, M.D., Ph.D.
Dr. Reshma Rangwala, M.D., Ph.D.
Executive Vice President, Chief Medical Officer
Executive Vice President, Chief Medical Officer
7.24K
+8.01%
Mr. Barry E. Greene
Mr. Barry E. Greene
Lead Independent Director
Lead Independent Director
907.00
--
Ms. Sohanya Cheng
Ms. Sohanya Cheng
Executive Vice President, Chief Commercial Officer
Executive Vice President, Chief Commercial Officer
--
--
Mr. Garen G. Bohlin
Mr. Garen G. Bohlin
Independent Director
Independent Director
--
--

Desglose de ingresos

La empresa aún no ha revelado los datos relevantes.
La empresa aún no ha revelado los datos relevantes.
Por negocio
Por región
La empresa aún no ha revelado los datos relevantes.

Estadísticas de accionistas

Actualizado: dom., 16 de nov
Actualizado: dom., 16 de nov
Accionistas
Tipos de accionistas
Accionistas
Accionistas
Proporción
T. Rowe Price Investment Management, Inc.
13.51%
Opaleye Management Inc.
5.57%
J. Wood Capital Advisors LLC
4.60%
Adage Capital Management, L.P.
2.47%
The Vanguard Group, Inc.
2.39%
Otro
71.45%
Accionistas
Accionistas
Proporción
T. Rowe Price Investment Management, Inc.
13.51%
Opaleye Management Inc.
5.57%
J. Wood Capital Advisors LLC
4.60%
Adage Capital Management, L.P.
2.47%
The Vanguard Group, Inc.
2.39%
Otro
71.45%
Tipos de accionistas
Accionistas
Proporción
Investment Advisor
18.95%
Hedge Fund
9.84%
Corporation
4.60%
Investment Advisor/Hedge Fund
2.40%
Individual Investor
2.32%
Venture Capital
0.92%
Research Firm
0.71%
Bank and Trust
0.06%
Otro
60.18%

Participación institucional

Actualizado: mié., 1 de oct
Actualizado: mié., 1 de oct
Periodo del informe
Número de instituciones
Acciones mantenidas
Proporción
Cambio
2025Q3
251
4.11M
24.14%
-1.36M
2025Q2
284
4.20M
48.66%
-1.75M
2025Q1
308
4.25M
49.43%
-1.53M
2024Q4
324
4.68M
55.67%
-1.51M
2024Q3
341
4.98M
60.06%
-2.16M
2024Q2
356
5.56M
67.54%
-2.08M
2024Q1
352
5.60M
72.46%
-1.99M
2023Q4
354
5.60M
73.31%
-2.02M
2023Q3
365
5.88M
77.33%
-1.69M
2023Q2
380
6.19M
81.48%
-2.04M
Ver más

Actividad de los accionistas

Nombre
Acciones mantenidas
Proporción
Cambio
Cambio %
Fecha
T. Rowe Price Investment Management, Inc.
728.77K
8.4%
+589.12K
+421.87%
Jun 30, 2025
J. Wood Capital Advisors LLC
458.13K
5.28%
--
--
Apr 10, 2025
Adage Capital Management, L.P.
421.32K
4.86%
--
--
Jun 30, 2025
The Vanguard Group, Inc.
518.27K
5.98%
+7.97K
+1.56%
Jun 30, 2025
BlackRock Institutional Trust Company, N.A.
184.85K
2.13%
-3.16K
-1.68%
Jun 30, 2025
Catalio Capital Management, LP
146.01K
1.68%
-9.61K
-6.17%
Jun 30, 2025
Avidity Partners Management LP
134.57K
1.55%
--
--
Jun 30, 2025
Marshall Wace LLP
128.45K
1.48%
--
--
Jun 30, 2025
Ver más

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Dividendos

Un total de 0.00 USD se ha distribuido en dividendos durante los últimos 5 años.
Fecha
Dividendos
Fecha de registro
Fecha de pago
Fecha ex-dividendo
Sin datos

División de acciones

Fecha
Tipo
Relación
Feb 24, 2025
Merger
15→1
Feb 24, 2025
Merger
15→1
Feb 24, 2025
Merger
15→1
Feb 24, 2025
Merger
15→1
Fecha
Tipo
Relación
Feb 24, 2025
Merger
15→1
Feb 24, 2025
Merger
15→1
Feb 24, 2025
Merger
15→1
Feb 24, 2025
Merger
15→1

Preguntas frecuentes

¿Quiénes son los cinco principales accionistas de Karyopharm Therapeutics Inc?

Los cinco principales accionistas de Karyopharm Therapeutics Inc son:
T. Rowe Price Investment Management, Inc. posee 728.77K acciones, lo que representa el 8.40% del total de acciones.
J. Wood Capital Advisors LLC posee 458.13K acciones, lo que representa el 5.28% del total de acciones.
Adage Capital Management, L.P. posee 421.32K acciones, lo que representa el 4.86% del total de acciones.
The Vanguard Group, Inc. posee 518.27K acciones, lo que representa el 5.98% del total de acciones.
BlackRock Institutional Trust Company, N.A. posee 184.85K acciones, lo que representa el 2.13% del total de acciones.

¿Cuáles son los tres principales tipos de accionista de Karyopharm Therapeutics Inc?

Los tres principales tipos de accionista de Karyopharm Therapeutics Inc son:
T. Rowe Price Investment Management, Inc.
Opaleye Management Inc.
J. Wood Capital Advisors LLC

¿Cuántas instituciones poseen acciones de Karyopharm Therapeutics Inc (KPTI)?

A fecha de 2025Q3, 251 instituciones poseen acciones de Karyopharm Therapeutics Inc, con un valor de mercado combinado de aproximadamente 4.11M, lo que representa el 24.14% del total de acciones. En comparación con el 2025Q2, el accionariado institucional ha aumentado en -24.51%.

¿Cuál es la mayor fuente de ganancias de Karyopharm Therapeutics Inc?

El --, el segmento empresarial -- generó la ganancia más alta para Karyopharm Therapeutics Inc, ascendiendo a -- y representando el --% de la ganancia total.
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