Adaptimmune Therapeutics PLC is focused on pre-clinical programs, including PRAME and CD70-directed T-cell therapies, and its allogeneic pipeline. PRAME is highly expressed across a range of solid tumors, including ovarian, endometrial, lung and breast cancers. The CD70 program targets the CD70 antigen, which is expressed across a range of hematological malignancies (acute myeloid leukemia and lymphoma) and solid tumors (renal cell carcinoma). It is using TRuC technology to develop a T-cell therapy (ADP-520) against CD70, with membrane bound IL-15 to enhance persistence. ADP-520 is in pre-clinical testing. TRuC technology combines the targeting of CAR-T cells with T-cell TCR signaling.
BörsenkürzelADAP
Name des UnternehmensAdaptimmune Therapeutics PLC
IPO-datumMay 06, 2015
CEORawcliffe (Adrian George)
Anzahl der mitarbeiter506
WertpapierartDepository Receipt
GeschäftsjahresendeMay 06
Addresse60 Jubilee Avenue
StadtABINGDON
BörseNASDAQ Capital Market Consolidated
LandUnited Kingdom
PostleitzahlOX14 4RX
Telefon441235430000
Websitehttps://www.adaptimmune.com/
BörsenkürzelADAP
IPO-datumMay 06, 2015
CEORawcliffe (Adrian George)
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