Fractyl Health gains as experimental procedure helps maintain weight-loss in study

ReutersSep 26, 2025 11:38 AM

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Shares of drug developer Fractyl Health GUTS.O rise 24.7% to $1.26 before the bell

Co says patients treated with its experimental lead product Revita preserved weight loss after GLP-1 drug discontinuation

Revita is an outpatient endoscopic procedure designed to modify dysfunction in the part of the small intestine through hydrothermal ablation in order to restore metabolic health

At 3 months, those treated with Revita lost an additional 2.5% total body weight after stopping Eli Lilly's LLY.N tirzepatide, the active ingredient in its blockbuster obesity drug Zepbound, while those who had a sham procedure regained 10%

Up to last close, stock down 51% YTD

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