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Royalty Pharma and J&J partner to develop autoimmune treatment

ReutersMar 30, 2026 12:58 PM

- Royalty Pharma RPRX.O said on Monday it has signed a $500 million research and development agreement with Johnson & Johnson JNJ.N to advance an experimental antibody treatment for autoimmune diseases.

Shares of Royalty Pharma were up 1.4% in premarket trading, while those of J&J rose nearly 0.7%.

  • The co-funding agreement, covering 2026 and 2027, will support the development of JNJ-4804, an experimental co-antibody therapy that targets IL 23 and TNF, two immune pathways involved in autoimmune inflammation.

  • Royalty Pharma CEO Pablo Legorreta said the drug holds promise for patients with chronic immune-mediated diseases and that the agreement builds on the company's investments in immunology, including earlier medicines targeting TNF.

  • The biopharmaceutical investor receives royalties on more than 35 commercial products, including Biogen's Tysabri and J&J's Tremfya - both targeting autoimmune disorders.

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