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Passage Bio's 2025 net loss narrows

ReutersMar 3, 2026 12:10 PM


Overview

  • Genetic medicines firm's net loss for 2025 was $45.5 mln, smaller than $64.8 mln loss in 2024

  • Company advancing upliFT-D study for frontotemporal dementia

  • Cash runway expected through Q1 2027


Outlook

  • Passage Bio expects interim safety data from upliFT-D study in 1H 2026

  • Company aims to declare Huntington's disease clinical candidate in 2H 2026

  • Passage Bio has cash runway through 1Q 2027


Result Drivers

  • CLINICAL PROGRESS - Passage Bio advanced its upliFT-D study by enrolling first FTD-GRN patients in Cohort 3 and treating first FTD-C9orf72 patient in Cohort 4

  • HUNTINGTON'S PROGRAM - Co advancing preclinical program for Huntington’s disease with clinical candidate selection expected in 2H 2026


Company press release: ID:nGNX2PqQgm


Key Details

Metric

Beat/Miss

Actual

Consensus Estimate

FY Net Income

-$45.52 mln

FY Income From Operations

-$49.30 mln


Analyst Coverage

  • The current average analyst rating on the shares is "buy" and the breakdown of recommendations is 6 "strong buy" or "buy", no "hold" and no "sell" or "strong sell"

  • The average consensus recommendation for the biotechnology & medical research peer group is "buy"

  • Wall Street's median 12-month price target for Passage Bio Inc is $32.00, about 264.5% above its March 2 closing price of $8.78


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