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Canada's Zymeworks 2025 revenue rises 39%

ReutersMar 2, 2026 11:08 AM


Overview

  • Biotechnology firm's 2025 revenue rose 39% yr/yr, driven by clinical milestones

  • Net loss for 2025 reduced by 34% compared to previous year

  • Company utilized $62.5 mln for share repurchases under current program


Outlook

  • Zymeworks expects adjusted operating expenses in 2026 to be 20% lower than 2025

  • Company anticipates regulatory milestone payments to fund operations beyond 2028

  • Zymeworks remains focused on timely execution of its novel strategy in 2026


Result Drivers

  • MILESTONE ACHIEVEMENTS - Revenue growth in 2025 was primarily driven by significant clinical and regulatory milestones achieved through collaborations with partners such as J&J and BeOne

  • ROYALTY TRANSITION - Transition of zanidatamab clinical activities to Jazz expected to reduce development-support revenue but increase royalty revenue over time

  • ROYALTY-BACKED FINANCING - $250 mln royalty-backed note financing with Royalty Pharma to support share repurchases and potential acquisitions


Company press release: ID:nGNXc8SC3P


Key Details

Metric

Beat/Miss

Actual

Consensus Estimate

Q4 Basic EPS

-$0.55

Q4 Operating Expenses

$46.67 mln


Analyst Coverage

  • The current average analyst rating on the shares is "buy" and the breakdown of recommendations is 14 "strong buy" or "buy", no "hold" and no "sell" or "strong sell"

  • The average consensus recommendation for the biotechnology & medical research peer group is "buy"

  • Wall Street's median 12-month price target for Zymeworks Inc is $34.00, about 46% above its February 27 closing price of $23.29


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