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Nautilus Q4 operating expenses fall 23%, net loss narrows

ReutersFeb 26, 2026 1:07 PM


Overview

  • Proteome analysis platform's Q4 operating expenses decreased 23% yr/yr

  • Net loss for Q4 narrowed compared to the previous year

  • Company does not anticipate material revenue from Early Access Program in 2026


Outlook

  • Company expects operating expenses to rise 15-20% in 2026

  • Nautilus anticipates no material revenue from Early Access Program in 2026

  • Company believes cash reserves will fund operations through 2027


Result Drivers

  • TAU PROTEOFORMS - Progress in processing and analyzing Tau proteoform samples supported platform validation and scientific publications

  • COST MANAGEMENT - Decrease in operating expenses attributed to reduced salaries, benefits, and development costs

  • EARLY ACCESS PROGRAM - Launched Iterative Mapping Early Access Program with encouraging initial customer response


Company press release: ID:nGNX2lMQfg


Key Details

Metric

Beat/Miss

Actual

Consensus Estimate

Q4 EPS

-$0.11

Q4 Net Income

-$13.78 mln

Q4 Operating Expenses

$15.42 mln


Analyst Coverage

  • The current average analyst rating on the shares is "strong buy" and the breakdown of recommendations is 2 "strong buy" or "buy", no "hold" and no "sell" or "strong sell"

  • The average consensus recommendation for the biotechnology & medical research peer group is "buy."

  • Wall Street's median 12-month price target for Nautilus Biotechnology Inc is $2.50, about 13.5% below its February 25 closing price of $2.89


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