Prelude Therapeutics Inc
PRLD1.760USD
-2.220-55.78%
Close 11/04, 16:00（ET）Quotes delayed by 15 min
99.61MMarket Cap
LossP/E TTM
More Details of Prelude Therapeutics Inc Company
Prelude Therapeutics Incorporated is a clinical-stage fully integrated oncology company built on a foundation of drug discovery to deliver novel precision cancer medicines to underserved patients. It has developed a diverse pipeline consisting of multiple distinct programs: kinases, targeted protein degraders, and precision antibody drug conjugates. Its product candidates include PRT3789, PRT2527 and PRT3645. PRT3789 is a highly selective degrader of SMARCA2 protein, which along with SMARCA4, controls gene regulation through chromatin remodeling. Its CDK9 program is an essential regulator of cancer-promoting transcriptional programs, including those driven by MCL1, MYC and MYB. PRT3645 is a brain and tissue penetrant molecule that potently targets CDK4/6 with a biased selectivity for CDK4. PRT2527 is designed to be a potent and selective CDK9 inhibitor. Its MCL1 candidate, PRT1419, is designed to be a potent and selective inhibitor of the anti-apoptotic protein, MCL1.
Prelude Therapeutics Inc Info
Ticker SymbolPRLD
Company namePrelude Therapeutics Inc
IPO dateSep 25, 2020
CEODr. Krishna (Kris) Vaddi, Ph.D.
Number of employees131
Security typeOrdinary Share
Fiscal year-endSep 25
Address175 Innovation Boulevard
CityWILMINGTON
Stock exchangeNASDAQ Global Select Consolidated
CountryUnited States of America
Postal code19805
Phone13024671280
Websitehttps://preludetx.com/
Ticker SymbolPRLD
IPO dateSep 25, 2020
CEODr. Krishna (Kris) Vaddi, Ph.D.
Company Executives of Prelude Therapeutics Inc
Name
Name/Position
Position
Shareholding
Change
Dr. Krishna (Kris) Vaddi, Ph.D.
Dr. Krishna (Kris) Vaddi, Ph.D.
Chief Executive Officer, Founder, Director
Chief Executive Officer, Founder, Director
3.67M
+29.33%
Dr. Paul A. Friedman, M.D.
Dr. Paul A. Friedman, M.D.
Independent Chairman of the Board
Independent Chairman of the Board
500.10K
--
Dr. Andrew P. Combs, Ph.D.
Dr. Andrew P. Combs, Ph.D.
Chief Chemistry Officer
Chief Chemistry Officer
480.12K
+27.99%
Dr. Peggy A. Scherle, Ph.D.
Dr. Peggy A. Scherle, Ph.D.
Chief Scientific Officer
Chief Scientific Officer
185.69K
+2.77%
Dr. Jane Huang, M.D.
Dr. Jane Huang, M.D.
President, Chief Medical Officer
President, Chief Medical Officer
96.29K
+6.67%
Ms. Katina Dorton
Ms. Katina Dorton
Director
Director
--
--
Dr. Paul Scherer, M.D.
Dr. Paul Scherer, M.D.
Independent Director
Independent Director
--
--
Dr. Victor Sandor, M.D.
Dr. Victor Sandor, M.D.
Independent Director
Independent Director
--
--
Mr. Bryant D. Lim, J.D.
Mr. Bryant D. Lim, J.D.
Chief Financial Officer, Chief Legal Officer, Corporate Secretary
Chief Financial Officer, Chief Legal Officer, Corporate Secretary
--
--
Dr. David P. Bonita, M.D.
Dr. David P. Bonita, M.D.
Independent Director
Independent Director
--
--
View more
Name
Name/Position
Position
Shareholding
Change
Dr. Krishna (Kris) Vaddi, Ph.D.
Dr. Krishna (Kris) Vaddi, Ph.D.
Chief Executive Officer, Founder, Director
Chief Executive Officer, Founder, Director
3.67M
+29.33%
Dr. Paul A. Friedman, M.D.
Dr. Paul A. Friedman, M.D.
Independent Chairman of the Board
Independent Chairman of the Board
500.10K
--
Dr. Andrew P. Combs, Ph.D.
Dr. Andrew P. Combs, Ph.D.
Chief Chemistry Officer
Chief Chemistry Officer
480.12K
+27.99%
Dr. Peggy A. Scherle, Ph.D.
Dr. Peggy A. Scherle, Ph.D.
Chief Scientific Officer
Chief Scientific Officer
185.69K
+2.77%
Dr. Jane Huang, M.D.
Dr. Jane Huang, M.D.
President, Chief Medical Officer
President, Chief Medical Officer
96.29K
+6.67%
Ms. Katina Dorton
Ms. Katina Dorton
Director
Director
--
--
Revenue Breakdown
No Data
No Data
By Business
By Region
No Data
Shareholding Stats
Updated: Tue, Aug 19
Updated: Tue, Aug 19
Shareholders
Shareholder Types
Shareholders
Shareholders
Proportion
OrbiMed Advisors, LLC
24.94%
Baker Bros. Advisors LP
23.14%
Vaddi (Krishna)
8.39%
The Vanguard Group, Inc.
2.13%
T. Rowe Price Associates, Inc.
2.09%
Other
39.32%
Shareholders
Shareholders
Proportion
OrbiMed Advisors, LLC
24.94%
Baker Bros. Advisors LP
23.14%
Vaddi (Krishna)
8.39%
The Vanguard Group, Inc.
2.13%
T. Rowe Price Associates, Inc.
2.09%
Other
39.32%
Shareholder Types
Shareholders
Proportion
Hedge Fund
26.36%
Private Equity
24.94%
Individual Investor
11.36%
Investment Advisor
7.69%
Investment Advisor/Hedge Fund
2.47%
Research Firm
0.66%
Venture Capital
0.10%
Other
26.43%
Institutional Shareholding
Updated: Wed, Oct 1
Updated: Wed, Oct 1
Reporting Period
No. of institutions
Shares Held
Proportion
Change
2025Q3
152
27.22M
62.21%
-14.73M
2025Q2
158
35.20M
80.72%
-13.66M
2025Q1
169
35.41M
81.20%
-13.64M
2024Q4
176
41.97M
99.49%
-4.74M
2024Q3
176
39.67M
94.09%
-11.21M
2024Q2
173
43.50M
103.37%
-2.47M
2024Q1
184
38.12M
90.60%
-8.41M
2023Q4
190
38.61M
71.39%
-9.45M
2023Q3
202
40.53M
76.60%
-4.90M
2023Q2
201
43.54M
105.11%
+2.58M
View more
Shareholder Activity
Name
Shares Held
Proportion
Change
Chg %
Date
OrbiMed Advisors, LLC
10.91M
24.94%
--
--
Jun 30, 2025
Baker Bros. Advisors LP
10.12M
23.14%
--
--
Jun 30, 2025
Vaddi (Krishna)
3.67M
8.39%
+832.02K
+29.33%
Mar 31, 2025
The Vanguard Group, Inc.
932.57K
2.13%
-76.63K
-7.59%
Jun 30, 2025
T. Rowe Price Associates, Inc.
914.94K
2.09%
-44.36K
-4.62%
Jun 30, 2025
Renaissance Technologies LLC
581.80K
1.33%
-74.90K
-11.41%
Jun 30, 2025
Acadian Asset Management LLC
540.57K
1.24%
+11.24K
+2.12%
Jun 30, 2025
Friedman (Paul A)
500.10K
1.14%
--
--
Mar 31, 2025
Combs (Andrew P)
480.12K
1.1%
+105.00K
+27.99%
Mar 31, 2025
Two Sigma Investments, LP
379.98K
0.87%
-64.09K
-14.43%
Jun 30, 2025
View more
Related ETFs
Updated: Sun, Nov 2
Updated: Sun, Nov 2
Name
Proportion
Global X Russell 2000 Covered Call ETF
0%
ProShares UltraPro Russell2000
0%
Dimensional US Core Equity 1 ETF
0%
iShares Micro-Cap ETF
0%
iShares Russell 2000 Value ETF
0%
Global X Russell 2000 ETF
0%
Schwab U.S. Small-Cap ETF
0%
Proshares Ultra Russell 2000
0%
iShares Russell 2000 ETF
0%
Schwab U.S. Broad Market ETF
0%
View more
Global X Russell 2000 Covered Call ETF
Proportion0%
ProShares UltraPro Russell2000
Proportion0%
Dimensional US Core Equity 1 ETF
Proportion0%
iShares Micro-Cap ETF
Proportion0%
iShares Russell 2000 Value ETF
Proportion0%
Global X Russell 2000 ETF
Proportion0%
Schwab U.S. Small-Cap ETF
Proportion0%
Proshares Ultra Russell 2000
Proportion0%
iShares Russell 2000 ETF
Proportion0%
Schwab U.S. Broad Market ETF
Proportion0%
Dividend
A total of
0.00
USD has been distributed in dividends over the past 5 years.
Date
Dividend
Record Date
Payment Date
Ex-dividend Date
No Data
Stock Split
Date
Type
Ratio
No Data
Date
Type
Ratio
No Data
