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Mereo BioPharma Group PLC

MREO
0.424USD
+0.050+13.20%
Close 02/06, 16:00ETQuotes delayed by 15 min
337.68MMarket Cap
LossP/E TTM

Mereo BioPharma Group PLC

0.424
+0.050+13.20%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Mereo BioPharma Group PLC

Currency: USD Updated: 2026-02-06

Key Insights

Mereo BioPharma Group PLC's fundamentals are relatively very healthy, with an industry-leading ESG disclosure.and its growth potential is high.Its valuation is considered undervalued, ranking 90 out of 392 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Buy, with the highest price target at 1.75.In the medium term, the stock price is expected to trend down.Despite a weak stock market performance over the past month, the company shows strong fundamentals and technicals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Mereo BioPharma Group PLC's Score

Industry at a Glance

Industry Ranking
90 / 392
Overall Ranking
217 / 4521
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Media Coverage

Last 24 hours
Coverage Level

Very Low
Very High
Positive

Mereo BioPharma Group PLC Highlights

StrengthsRisks
Mereo BioPharma Group plc is a biopharmaceutical company focused on the development of therapeutics for rare diseases. The Company has developed a portfolio of late-stage clinical product candidates, and its two rare disease product candidates are setrusumab for the treatment of osteogenesis imperfecta (OI) and alvelestat primarily for the treatment of severe alpha-1 antitrypsin deficiency-associated lung disease (AATD-LD). In addition to the rare disease programs, it has two oncology product candidates in clinical development, which include Etigilimab, an IgG1 monoclonal antibody which binds to the human T-cell immunoreceptor with Ig and ITIM domains (TIGIT) receptor on immune cells to improve the activation and effectiveness of T-cell and NK cell antitumor activity and Navicixizumab is a bispecific antibody that inhibits delta-like ligand 4 (DLL4) and vascular endothelial growth factor (VEGF). Navicixizumab is developed for the treatment of late-line ovarian cancer.
Overvalued
The company’s latest PE is -1.58, at a high 3-year percentile range.
Institutional Buying
The latest institutional holdings are 114.49M shares, increasing 0.55% quarter-over-quarter.
Held by James Simons
Star Investor James Simons holds 590.87K shares of this stock.
Lower Market Activity
The company has less investor interest, with a 20-day turnover ratio of -0.10.

Analyst Rating

Based on 8 analysts
Buy
Current Rating
1.750
Target Price
+326.83%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Financial Health

Currency: USD Updated: 2026-02-06

The current financial score of Mereo BioPharma Group PLC is 7.58, ranking 97 out of 392 in the Biotechnology & Medical Research industry. Its financial status is robust, and its operating efficiency is low.

Score

Industry at a Glance

Previous score
7.58
Change
0

Financials

10.00

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

7.45

Operational Efficiency

2.86

Growth Potential

10.00

Shareholder Returns

7.58

Mereo BioPharma Group PLC's Company Valuation

Currency: USD Updated: 2026-02-06

The current valuation score of Mereo BioPharma Group PLC is 7.17, ranking 159 out of 392 in the Biotechnology & Medical Research industry. Its current P/E ratio is -1.58, which is -32.77% below the recent high of -1.06 and -5700.94% above the recent low of -91.85.

Score

Industry at a Glance

Previous score
7.17
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 90/392
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2026-02-06

The current earnings forecast score of Mereo BioPharma Group PLC is 8.25, ranking 147 out of 392 in the Biotechnology & Medical Research industry. The average price target is 7.00, with a high of 9.00 and a low of 5.00.

Score

Industry at a Glance

Previous score
8.25
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 8 analysts
Buy
Current Rating
1.750
Target Price
+326.83%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

542
Total
6
Median
6
Average
Company name
Ratings
Analysts
Mereo BioPharma Group PLC
MREO
8
CRISPR Therapeutics AG
CRSP
29
argenx SE
ARGX
26
IQVIA Holdings Inc
IQV
26
Beigene Ltd
ONC
24
Intellia Therapeutics Inc
NTLA
24
1
2
3
...
109

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2026-02-06

The current price momentum score of Mereo BioPharma Group PLC is 6.50, ranking 233 out of 392 in the Biotechnology & Medical Research industry. Currently, the stock price is trading between the resistance level at 0.68 and the support level at 0.27, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
6.39
Change
0.11

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(2)
Neutral(3)
Buy(2)
Indicators
Value
Direction
MACD(12,26,9)
0.075
Neutral
RSI(14)
32.971
Neutral
STOCH(KDJ)(9,3,3)
24.274
Buy
ATR(14)
0.055
Low Volatility
CCI(14)
-89.516
Neutral
Williams %R
78.949
Sell
TRIX(12,20)
-3.883
Sell
StochRSI(14)
100.000
Buy
Moving Average
Sell(5)
Neutral(0)
Buy(1)
Indicators
Value
Direction
MA5
0.413
Buy
MA10
0.436
Sell
MA20
0.513
Sell
MA50
1.180
Sell
MA100
1.544
Sell
MA200
1.854
Sell

Institutional Confidence

Currency: USD Updated: 2026-02-06

The current institutional shareholding score of Mereo BioPharma Group PLC is 7.00, ranking 86 out of 392 in the Biotechnology & Medical Research industry. The latest institutional shareholding proportion is 71.95%, representing a quarter-over-quarter increase of 2.47%. The largest institutional shareholder is James Simons, holding a total of 590.87K shares, representing 0.37% of shares outstanding, with 56.29% decrease in holdings.

Score

Industry at a Glance

Previous score
7.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
Janus Henderson Investors
16.29M
-7.91%
Rubric Capital Management LP
15.31M
--
683 Capital Management LLC
13.02M
+167.01%
Northpond Ventures, LLC
10.90M
--
Frazier Life Sciences Management, L.P.
9.44M
--
Mangrove Partners
7.79M
-9.79%
Rock Springs Capital Management LP
4.57M
+2.36%
Clearline Capital LP
3.83M
+5.97%
Alkeon Capital Management LLC
3.70M
-21.29%
1
2

Risk Assessment

Currency: USD Updated: 2026-02-06

The U.S. Dollar Index is currently in a neutral state, which has a neutral effect on the Biotechnology & Medical Research domestic-focused industry. The Dollar Index (DXY) measures the value of the U.S. dollar against a basket of major currencies, including the euro, yen, pound sterling, Canadian dollar, Swedish krona, and Swiss franc. The current risk assessment score of Mereo BioPharma Group PLC is 1.30, ranking 328 out of 392 in the Biotechnology & Medical Research industry. The company's beta value is 0.28. This indicates that the stock tends to underperform the index during upward trending markets but experiences smaller declines during downward trending markets. with an industry-leading ESG disclosure.

Score

Industry at a Glance

Previous score
1.30
Change
0
Beta vs S&P 500 index
0.27
VaR
+7.34%
240-Day Maximum Drawdown
+90.29%
240-Day Volatility
+252.00%

Return

Best Daily Return
60 days
+29.82%
120 days
+29.82%
5 years
+62.50%
Worst Daily Return
60 days
-87.65%
120 days
-87.65%
5 years
-87.65%
Sharpe Ratio
60 days
-0.01
120 days
+0.10
5 years
+0.22

Risk Assessment

Maximum Drawdown
240 days
+90.29%
3 years
+94.14%
5 years
+94.14%
Return-to-Drawdown Ratio
240 days
-0.93
3 years
-0.16
5 years
-0.19
Skewness
240 days
-4.61
3 years
-4.07
5 years
-1.13

Volatility

Realised Volatility
240 days
+252.00%
5 years
+144.72%
Standardised True Range
240 days
+33.99%
5 years
+36.96%
Downside Risk-Adjusted Return
120 days
+9.11%
240 days
+9.11%
Maximum Daily Upside Volatility
60 days
+234.84%
Maximum Daily Downside Volatility
60 days
+195.44%

Liquidity

Average Turnover Rate
60 days
+0.30%
120 days
+0.24%
5 years
--
Turnover Deviation
20 days
-10.09%
60 days
+65.70%
120 days
+31.31%

Peer Comparison

Biotechnology & Medical Research
Mereo BioPharma Group PLC
Mereo BioPharma Group PLC
MREO
6.75 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Alkermes Plc
Alkermes Plc
ALKS
8.60 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Ascendis Pharma A/S
Ascendis Pharma A/S
ASND
8.53 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Ionis Pharmaceuticals Inc
Ionis Pharmaceuticals Inc
IONS
8.38 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
IQVIA Holdings Inc
IQVIA Holdings Inc
IQV
8.37 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
BioCryst Pharmaceuticals Inc
BioCryst Pharmaceuticals Inc
BCRX
8.17 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
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