The current institutional shareholding score of Karyopharm Therapeutics Inc is 5.00, ranking 73 out of 157 in the Pharmaceuticals industry. The latest institutional shareholding proportion is 62.56%, representing a quarter-over-quarter increase of 72.34%. The largest institutional shareholder is James Simons, holding a total of 0.00 shares, representing 0.47% of shares outstanding, with 1.05% increase in holdings.