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Iterum Therapeutics PLC

ITRM
0.370USD
-0.011-2.86%
Close 12/19, 16:00ETQuotes delayed by 15 min
18.13MMarket Cap
LossP/E TTM

Iterum Therapeutics PLC

0.370
-0.011-2.86%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Iterum Therapeutics PLC

Currency: USD Updated: 2025-12-19

Key Insights

Iterum Therapeutics PLC's fundamentals are relatively healthy, and its growth potential is significant.Its valuation is considered fairly valued, ranking 164/404 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Buy, with the highest price target at 5.50.In the medium term, the stock price is expected to trend down.The company has shown average stock market performance over the past month, with weak fundamentals and technicals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Iterum Therapeutics PLC's Score

Industry at a Glance

Industry Ranking
164 / 404
Overall Ranking
294 / 4582
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Analyst Rating

Based on 2 analysts
Buy
Current Rating
5.500
Target Price
+1127.13%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Iterum Therapeutics PLC Highlights

StrengthsRisks
Iterum Therapeutics plc is a clinical-stage pharmaceutical company. The Company develops differentiated anti-infectives. It offers ORLYNVAH (sulopenem in an oral tablet formulation) medicine, which is an oral penem antibiotic for the treatment of uncomplicated urinary tract infections caused by the designated microorganisms Escherichia coli, Klebsiella pneumoniae, or Proteus mirabilis in adult women. Sulopenem is a potent, thiopenem antibiotic delivered intravenously which is active against bacteria that belong to the group of organisms known as gram-negatives and cause urinary tract and intra-abdominal infections. The Company operates as a single business segment, which is the development and commercialization of treatments for drug-resistant bacterial infections.
Fairly Valued
The company’s latest PE is -0.51, at a medium 3-year percentile range.
Institutional Selling
The latest institutional holdings are 2.44M shares, decreasing 19.26% quarter-over-quarter.
Held by James Simons
Star Investor James Simons holds 81.69K shares of this stock.

Financial Health

Currency: USD Updated: 2025-12-19

The current financial score of Iterum Therapeutics PLC is 5.79, ranking 335/404 in the Biotechnology & Medical Research industry. Its financial status is stable, and its operating efficiency is low.

Score

Industry at a Glance

Previous score
5.79
Change
0

Financials

6.14

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

7.44

Operational Efficiency

2.83

Growth Potential

5.45

Shareholder Returns

7.07

Iterum Therapeutics PLC's Company Valuation

Currency: USD Updated: 2025-12-19

The current valuation score of Iterum Therapeutics PLC is 7.65, ranking 100/404 in the Biotechnology & Medical Research industry. Its current P/E ratio is -0.51, which is -100.00% below the recent high of 0.00 and -205.95% above the recent low of -1.57.

Score

Industry at a Glance

Previous score
7.65
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 164/404
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2025-12-19

The current earnings forecast score of Iterum Therapeutics PLC is 8.00, ranking 168/404 in the Biotechnology & Medical Research industry. The average price target for Iterum Therapeutics PLC is 5.50, with a high of 9.00 and a low of 2.00.

Score

Industry at a Glance

Previous score
8.00
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 2 analysts
Buy
Current Rating
5.500
Target Price
+1127.13%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

534
Total
6
Median
6
Average
Company name
Ratings
Analysts
Iterum Therapeutics PLC
ITRM
2
CRISPR Therapeutics AG
CRSP
30
IQVIA Holdings Inc
IQV
25
argenx SE
ARGX
25
Intellia Therapeutics Inc
NTLA
25
Ionis Pharmaceuticals Inc
IONS
24
1
2
3
...
107

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2025-12-19

The current price momentum score of Iterum Therapeutics PLC is 5.79, ranking 320/404 in the Biotechnology & Medical Research industry. Currently, the stock price is trading between the resistance level at 0.49 and the support level at 0.31, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
6.00
Change
-0.21

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(2)
Neutral(2)
Buy(0)
Indicators
Value
Direction
MACD(12,26,9)
0.000
Neutral
RSI(14)
32.587
Neutral
STOCH(KDJ)(9,3,3)
4.381
Oversold
ATR(14)
0.041
Low Volatility
CCI(14)
-136.532
Sell
Williams %R
100.000
Oversold
TRIX(12,20)
-0.975
Sell
StochRSI(14)
0.000
Oversold
Moving Average
Sell(6)
Neutral(0)
Buy(0)
Indicators
Value
Direction
MA5
0.393
Sell
MA10
0.424
Sell
MA20
0.431
Sell
MA50
0.544
Sell
MA100
0.631
Sell
MA200
0.851
Sell

Institutional Confidence

Currency: USD Updated: 2025-12-19

The current institutional shareholding score of Iterum Therapeutics PLC is 3.00, ranking 197/404 in the Biotechnology & Medical Research industry. The latest institutional shareholding proportion is 5.09%, representing a quarter-over-quarter increase of 29.82%. The largest institutional shareholder is James Simons, holding a total of 81.69K shares, representing 0.15% of shares outstanding, with 74.30% decrease in holdings.

Score

Industry at a Glance

Previous score
3.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
Squarepoint Capital LLP
456.86K
--
Apollon Financial LLC
250.25K
--
Dunne (Michael W)
235.00K
+6.82%
OneDigital Investment Advisors LLC
161.00K
+59.41%
Fishman (Corey N)
137.06K
--
CAPTRUST Financial Advisors
11.50K
--
Renaissance Technologies LLC
Star Investors
471.90K
+95.89%
1
2

Risk Assessment

Currency: USD Updated: 2025-12-19

The current risk assessment score of Iterum Therapeutics PLC is 2.82, ranking 201/404 in the Biotechnology & Medical Research industry. The company's beta value is 2.86. This indicates that the stock tends to outperform the index during upward trending markets but experiences larger declines during downward trending markets.

Score

Industry at a Glance

Previous score
2.82
Change
0
Beta vs S&P 500 index
2.86
VaR
+8.07%
240-Day Maximum Drawdown
+81.71%
240-Day Volatility
+89.66%

Return

Best Daily Return
60 days
+11.23%
120 days
+13.61%
5 years
+60.68%
Worst Daily Return
60 days
-22.95%
120 days
-22.95%
5 years
-44.20%
Sharpe Ratio
60 days
-2.97
120 days
-2.17
5 years
-0.35

Risk Assessment

Maximum Drawdown
240 days
+81.71%
3 years
+100.00%
5 years
+100.00%
Return-to-Drawdown Ratio
240 days
-1.00
3 years
-0.25
5 years
-0.20
Skewness
240 days
+0.39
3 years
+2.08
5 years
+1.19

Volatility

Realised Volatility
240 days
+89.66%
5 years
--
Standardised True Range
240 days
+18.95%
5 years
+101.48%
Downside Risk-Adjusted Return
120 days
-305.58%
240 days
-305.58%
Maximum Daily Upside Volatility
60 days
+95.95%
Maximum Daily Downside Volatility
60 days
+70.04%

Liquidity

Average Turnover Rate
60 days
+2.31%
120 days
+1.80%
5 years
--
Turnover Deviation
20 days
-100.00%
60 days
-100.00%
120 days
-100.00%

Peer Comparison

Biotechnology & Medical Research
Iterum Therapeutics PLC
Iterum Therapeutics PLC
ITRM
5.94 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Amicus Therapeutics Inc
Amicus Therapeutics Inc
FOLD
8.80 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Krystal Biotech Inc
Krystal Biotech Inc
KRYS
8.42 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Charles River Laboratories International Inc
Charles River Laboratories International Inc
CRL
8.41 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Madrigal Pharmaceuticals Inc
Madrigal Pharmaceuticals Inc
MDGL
8.35 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
IQVIA Holdings Inc
IQVIA Holdings Inc
IQV
8.30 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
View more

FAQs

How does TradingKey generate the Stock Score of Iterum Therapeutics PLC?

The TradingKey Stock Score provides a comprehensive assessment of Iterum Therapeutics PLC based on 34 indicators derived from over 100 underlying data points.
These indicators are categorised into six key dimensions: financial health, company profile, earnings forecasts, price momentum, institutional confidence, and risk assessment, collectively providing investors with a thorough analysis of Iterum Therapeutics PLC’s performance and outlook.

How do we generate the financial health score of Iterum Therapeutics PLC?

To generate the financial health score of Iterum Therapeutics PLC, we analyse various key financial indicators across several core dimensions, including financial fundamentals, earnings quality, operational efficiency, growth potential, and shareholder returns.
By integrating these comprehensive data, the financial health score not only reflects Iterum Therapeutics PLC's overall stability, operational efficiency, and growth potential but also captures the investment returns delivered to shareholders. This score aims to support rational decision-making for investors and other stakeholders. A higher score indicates a better financial health of Iterum Therapeutics PLC.

How do we generate the company valuation score of Iterum Therapeutics PLC?

To generate the company valuation score of Iterum Therapeutics PLC, we use several key financial ratios, including P/E, P/B, P/S, and P/CF. These metrics compare Iterum Therapeutics PLC’s market value to its earnings, assets, sales, and cash flow, serving as core indicators for assessing company value.
By analysing these ratios in an all-round manner, the valuation score reflects not only the market’s current perception of Iterum Therapeutics PLC’s value but also its future profitability and growth potential, thereby supporting more informed investment decisions. A higher score indicates a fairer valuation of Iterum Therapeutics PLC.

How do we generate the earnings forecast score of Iterum Therapeutics PLC?

To calculate the earnings forecast score of Iterum Therapeutics PLC, we consider various key indicators such as analyst ratings, financial forecasts, support and resistance levels, and peer comparisons:
Current ratings and price targets directly reflect analysts’ expectations, while the upside space indicates their views on the stock’s growth potential.
Financial metrics like earnings per share (EPS), revenue, net income, and earnings before interest and taxes (EBIT) are core measures for assessing profitability.
By analysing the high, median, and low ranges of the target price, we can identify price trends and determine key support and resistance levels.
Comparing these indicators against peers provides context for the stock’s performance and helps anchor more realistic expectations.
These factors together form a comprehensive earnings forecast score that accurately reflects the stock’s expected financial performance and growth potential. A higher score suggests that analysts have a more optimistic outlook on Iterum Therapeutics PLC’s future.

How do we generate the price momentum score of Iterum Therapeutics PLC?

When generating the price momentum score for Iterum Therapeutics PLC, we examine momentum indicators including support and resistance levels as well as volume metrics.
Support levels represent price points where buying interest is strong enough to prevent further declines, while resistance levels indicate prices where selling pressure may hinder upward movement. By analysing typical price volume alongside total volume, we assess overall market activity and liquidity. These indicators help identify price trends and potential shifts, enabling more accurate predictions of future earnings.
This comprehensive approach can reflect market sentiment and enable rational forecasts of Iterum Therapeutics PLC’s prices. A higher score indicates a more stable short-term price trend for Iterum Therapeutics PLC.

How do we generate the institutional confidence score of Iterum Therapeutics PLC?

To generate the institutional confidence score of Iterum Therapeutics PLC, we analyse both the proportion of shares held by institutions and the number of shares they own. A higher institutional ownership percentage indicates strong confidence of professional investors, which is generally a positive signal about Iterum Therapeutics PLC’s potential. By examining the number of shares held, we gain deeper insight into institutions’ commitment and attitude toward the stock, as institutional investors typically conduct thorough analysis before making investment decisions. Understanding institutional confidence helps us refine earnings forecasts and provides a more reliable perspective on the company’s future performance and market stability. A higher score indicates greater institutional endorsement of Iterum Therapeutics PLC.

How do we generate the risk management score of Iterum Therapeutics PLC?

To assess the risk management score of Iterum Therapeutics PLC, we examine multiple key indicators related to returns, risk, volatility, and liquidity.
The highest and lowest daily returns reflect the potential size of gains and losses, while the Sharpe ratio measures risk-adjusted return performance. On the risk side, we analyse maximum drawdown and the return-to-drawdown ratio to identify extreme loss scenarios. Skewness helps assess the distribution of returns and whether performance may be biased. Volatility indicators—such as realised volatility and standardised true range—reveal price fluctuations. Downside risk-adjusted returns provide insight into potential losses and gains. Lastly, liquidity metrics like average turnover rate and turnover deviation indicate how actively the stock is traded.
These indicators together provide a multi-dimensional understanding of Iterum Therapeutics PLC’s risk-return profile, serving as core factors of the risk management score. A higher score indicates lower risk on the side of Iterum Therapeutics PLC.
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