Denali Therapeutics Inc
DNLI13.785USD
+0.345+2.57%
Market hours （ET）Quotes delayed by 15 min
2.00BMarket Cap
LossP/E TTM
More Details of Denali Therapeutics Inc Company
Denali Therapeutics Inc. is a biopharmaceutical company. The Company is focused on developing a portfolio of product candidates engineered to cross the blood-brain barrier (BBB) for neurodegenerative diseases and lysosomal storage disease. The Company has a portfolio of both small molecule and biotherapeutic medicines, comprising seven product candidates in clinical development across seven indications as well as preclinical therapeutic candidates. Its three late-stage development programs include tividenofusp alfa (DNL310) for mucopolysaccharidosis II (MPS II); BIIB122/DNL151 (LRRK2 inhibitor) for Parkinson’s disease; and DNL343 (eIF2B activator) for amyotrophic lateral sclerosis (ALS). SAR443820/DNL788 (RIPK1 inhibitor) is being evaluated in a Phase II study for multiple sclerosis (MS). In addition, it has a Phase I/II study of TAK-594/DNL593 for frontotemporal dementia-granulin (FTD-GRN) and a Phase I/II study of DNL126 for MPS IIIA (Sanfilippo syndrome).
Company Info
Ticker SymbolDNLI
Company nameDenali Therapeutics Inc
IPO dateDec 08, 2017
CEODr. Ryan J. Watts, Ph.D.
Number of employees422
Security typeOrdinary Share
Fiscal year-endDec 08
Address161 Oyster Point Blvd.
CitySOUTH SAN FRANCISCO
Stock exchangeNASDAQ Global Select Consolidated
CountryUnited States of America
Postal code94080
Phone16508668547
Websitehttps://www.denalitherapeutics.com
Ticker SymbolDNLI
IPO dateDec 08, 2017
CEODr. Ryan J. Watts, Ph.D.
Company Executives
Name
Name/Position
Position
Shareholding
Change
Dr. Ryan J. Watts, Ph.D.
Dr. Ryan J. Watts, Ph.D.
President, Chief Executive Officer, Director
President, Chief Executive Officer, Director
2.46M
--
Dr. Alexander O. Schuth, M.D.
Dr. Alexander O. Schuth, M.D.
Chief Operating and Financial Officer, Secretary
Chief Operating and Financial Officer, Secretary
768.06K
+20.52%
Dr. Carole Ho, M.D.
Dr. Carole Ho, M.D.
Chief Medical Officer, Head of Development
Chief Medical Officer, Head of Development
383.89K
+50.87%
Mr. Jay T. Flatley
Mr. Jay T. Flatley
Independent Director
Independent Director
352.53K
+1.74%
Dr. David P. Schenkein, M.D.
Dr. David P. Schenkein, M.D.
Independent Director
Independent Director
72.72K
+9.05%
Mr. Peter S. Klein
Mr. Peter S. Klein
Independent Director
Independent Director
27.53K
+28.08%
Ms. Jennifer E. Cook
Ms. Jennifer E. Cook
Independent Director
Independent Director
26.07K
+30.13%
Dr. Marc Tessier-Lavignec, Ph.D.
Dr. Marc Tessier-Lavignec, Ph.D.
Independent Director
Independent Director
--
--
Mr. Steven E. (Steve) Krognes
Mr. Steven E. (Steve) Krognes
Director
Director
--
--
Ms. Nancy A. Thornberry
Ms. Nancy A. Thornberry
Independent Director
Independent Director
--
--
View more
Name
Name/Position
Position
Shareholding
Change
Dr. Ryan J. Watts, Ph.D.
Dr. Ryan J. Watts, Ph.D.
President, Chief Executive Officer, Director
President, Chief Executive Officer, Director
2.46M
--
Dr. Alexander O. Schuth, M.D.
Dr. Alexander O. Schuth, M.D.
Chief Operating and Financial Officer, Secretary
Chief Operating and Financial Officer, Secretary
768.06K
+20.52%
Dr. Carole Ho, M.D.
Dr. Carole Ho, M.D.
Chief Medical Officer, Head of Development
Chief Medical Officer, Head of Development
383.89K
+50.87%
Mr. Jay T. Flatley
Mr. Jay T. Flatley
Independent Director
Independent Director
352.53K
+1.74%
Dr. David P. Schenkein, M.D.
Dr. David P. Schenkein, M.D.
Independent Director
Independent Director
72.72K
+9.05%
Mr. Peter S. Klein
Mr. Peter S. Klein
Independent Director
Independent Director
27.53K
+28.08%
Revenue Breakdown
No Data
No Data
By Business
By Region
No Data
Shareholding Stats
Updated: Fri, Jul 25
Updated: Fri, Jul 25
Shareholders
Shareholder Types
Shareholders
Shareholders
Proportion
Baillie Gifford & Co.
8.32%
The Vanguard Group, Inc.
8.10%
Wellington Management Company, LLP
7.85%
BlackRock Institutional Trust Company, N.A.
6.91%
Fidelity Management & Research Company LLC
5.02%
Other
63.80%
Shareholders
Shareholders
Proportion
Baillie Gifford & Co.
8.32%
The Vanguard Group, Inc.
8.10%
Wellington Management Company, LLP
7.85%
BlackRock Institutional Trust Company, N.A.
6.91%
Fidelity Management & Research Company LLC
5.02%
Other
63.80%
Shareholder Types
Shareholders
Proportion
Investment Advisor
50.41%
Investment Advisor/Hedge Fund
27.07%
Hedge Fund
10.45%
Individual Investor
4.94%
Corporation
4.93%
Sovereign Wealth Fund
4.42%
Research Firm
2.34%
Pension Fund
0.51%
Bank and Trust
0.30%
Institutional Shareholding
Updated: Tue, Jul 1
Updated: Tue, Jul 1
Reporting Period
No. of institutions
Shares Held
Proportion
Change
2025Q2
524
153.35M
105.55%
-12.15M
2025Q1
537
151.12M
104.03%
-14.77M
2024Q4
523
145.56M
100.28%
-21.13M
2024Q3
518
152.07M
106.51%
-14.19M
2024Q2
504
147.18M
103.45%
-5.80M
2024Q1
491
145.33M
102.36%
+2.75M
2023Q4
499
138.06M
99.94%
+3.21M
2023Q3
492
132.50M
96.48%
-2.55M
2023Q2
504
131.32M
95.95%
-3.31M
2023Q1
503
131.21M
95.98%
-630.06K
View more
Shareholder Activity
Name
Shares Held
Proportion
Change
Chg %
Date
Baillie Gifford & Co.
12.09M
8.32%
-223.89K
-1.82%
Mar 31, 2025
The Vanguard Group, Inc.
11.77M
8.1%
-221.47K
-1.85%
Mar 31, 2025
Wellington Management Company, LLP
11.41M
7.85%
+1.56M
+15.86%
Mar 31, 2025
BlackRock Institutional Trust Company, N.A.
10.04M
6.91%
-56.41K
-0.56%
Mar 31, 2025
Fidelity Management & Research Company LLC
7.29M
5.02%
-712.15K
-8.90%
Mar 31, 2025
Biogen Inc
7.16M
4.93%
-5.60M
-43.89%
Oct 30, 2024
Temasek Holdings Pte. Ltd.
5.36M
3.69%
--
--
Mar 31, 2025
UBS Asset Management (Switzerland)
4.88M
3.36%
+1.49M
+43.92%
Mar 31, 2025
Capital Research Global Investors
4.77M
3.28%
-712.07K
-13.00%
Mar 31, 2025
State Street Global Advisors (US)
4.46M
3.07%
-84.22K
-1.85%
Mar 31, 2025
View more
Related ETFs
Updated: Sat, Aug 2
Updated: Sat, Aug 2
Name
Proportion
iShares Neuroscience and Healthcare ETF
4.17%
Tema Neuroscience and Mental Health ETF
2.07%
ALPS Medical Breakthroughs ETF
1.37%
Global X Guru Index ETF
1.24%
Virtus LifeSci Biotech Clinical Trials ETF
0.84%
BNY Mellon Innovators ETF
0.47%
SPDR S&P Biotech ETF
0.43%
Global X Aging Population ETF
0.33%
iShares Health Innovation Active ETF
0.26%
Direxion Daily S&P Biotech Bull 3X Shares
0.25%
View more
iShares Neuroscience and Healthcare ETF
Proportion4.17%
Tema Neuroscience and Mental Health ETF
Proportion2.07%
ALPS Medical Breakthroughs ETF
Proportion1.37%
Global X Guru Index ETF
Proportion1.24%
Virtus LifeSci Biotech Clinical Trials ETF
Proportion0.84%
BNY Mellon Innovators ETF
Proportion0.47%
SPDR S&P Biotech ETF
Proportion0.43%
Global X Aging Population ETF
Proportion0.33%
iShares Health Innovation Active ETF
Proportion0.26%
Direxion Daily S&P Biotech Bull 3X Shares
Proportion0.25%
Dividend
A total of
0.00
USD has been distributed in dividends over the past 5 years.
Date
Dividend
Record Date
Payment Date
Ex-dividend Date
No Data
Stock Split
Date
Type
Ratio
No Data
Date
Type
Ratio
No Data
