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ALX Oncology Holdings Inc

ALXO
1.460USD
-0.110-7.01%
Close 11/04, 16:00ETQuotes delayed by 15 min
78.12MMarket Cap
LossP/E TTM

ALX Oncology Holdings Inc

1.460
-0.110-7.01%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of ALX Oncology Holdings Inc

Currency: USD Updated: 2025-11-03

Key Insights

The company's fundamentals are relatively weak. Its valuation is considered fairly valued,and institutional recognition is very high. Over the past 30 days, multiple analysts have rated the company as a Buy. The company shows weak stock market performance, in line with its weak fundamentals and technicals. The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

ALX Oncology Holdings Inc's Score

Industry at a Glance

Industry Ranking
136 / 407
Overall Ranking
265 / 4617
Industry
Biotechnology & Medical Research

Support & Resistance

No Data

Score Analysis

Current score
Previous score

Analyst Rating

Based on 4 analysts
Buy
Current Rating
2.667
Target Price
+73.16%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

ALX Oncology Holdings Inc Highlights

StrengthsRisks
ALX Oncology Holdings Inc. is a clinical-stage immuno-oncology company focused on helping patients fight cancer by developing therapies that block the CD47 immune checkpoint inhibitor and bridge the innate and adaptive immune system. Its product candidate, evorpacept, is a CD47 blocking therapeutic that combines a high-affinity CD47 binding domain with an inactivated, proprietary Fc domain. It is engaged in focusing on combining evorpacept with anti-cancer antibodies, ADCs, and PD-1/PD-L1 immune checkpoint inhibitors. Cancer cells leverage CD47, a cell surface protein, as a don’t eat me signal to evade macrophage phagocytosis or as a don't activate T-cells signal that prevents activation of T-cells by dendritic cells. It focuses on combining evorpacept with anti-cancer antibodies, ADCs, and PD-1/PD-L1 immune checkpoint inhibitors. It also has a preclinical program focused on developing ALTA-002, a SIRPa TRAAC that offers ways to engage the innate and adaptive immune response to cancer.
Fairly Valued
The company’s latest PE is -0.73, at a medium 3-year percentile range.
Institutional Selling
The latest institutional holdings are 36.64M shares, decreasing 37.88% quarter-over-quarter.
Held by James Simons
Star Investor James Simons holds 85.40K shares of this stock.
Higher Market Activity
The company has more investor interest, with a 20-day turnover ratio of 0.59.

Financial Health

Currency: USD Updated: 2025-11-03

The company's current financial score is 5.40, which is lower than the Biotechnology & Medical Research industry's average of 6.92. Its financial status is weak, and its operating efficiency is low.

Score

Industry at a Glance

Previous score
5.40
Change
0

Financials

2.04

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
No Data

Quality of Earnings

7.20

Operational Efficiency

4.00

Growth Potential

6.75

Shareholder Returns

7.03

ALX Oncology Holdings Inc's Company Valuation

Currency: USD Updated: 2025-11-03

The company’s current valuation score is 8.74, which is higher than the Biotechnology & Medical Research industry's average of 7.05. Its current P/E ratio is -0.73, which is -77.19% below the recent high of -0.17 and -551.70% above the recent low of -4.73.

Score

Industry at a Glance

Previous score
8.74
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 136/407
No Data

Earnings Forecast

Currency: USD Updated: 2025-11-03

The company’s current earnings forecast score is 8.50, which is higher than the Biotechnology & Medical Research industry's average of 8.01. The average price target for ALX Oncology Holdings Inc is 3.00, with a high of 3.00 and a low of 2.00.

Score

Industry at a Glance

Previous score
8.00
Change
0.5

Support & Resistance

No Data

Analyst Rating

Based on 4 analysts
Buy
Current Rating
2.667
Target Price
+69.85%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

521
Total
6
Median
6
Average
Company name
Ratings
Analysts
ALX Oncology Holdings Inc
ALXO
4
CRISPR Therapeutics AG
CRSP
30
Intellia Therapeutics Inc
NTLA
25
IQVIA Holdings Inc
IQV
25
Ionis Pharmaceuticals Inc
IONS
25
argenx SE
ARGX
25
1
2
3
...
104

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
No Data

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2025-11-03

The company’s current price momentum score is 5.73, which is lower than the Biotechnology & Medical Research industry's average of 6.58. Sideways: Currently, the stock price is trading between the resistance level at 1.98 and the support level at 1.33, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
5.82
Change
-0.09

Support & Resistance

No Data

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(3)
Neutral(2)
Buy(0)
Indicators
Value
Direction
MACD(12,26,9)
-0.084
Neutral
RSI(14)
43.936
Neutral
STOCH(KDJ)(9,3,3)
8.663
Oversold
ATR(14)
0.138
High Vlolatility
CCI(14)
-112.224
Sell
Williams %R
100.000
Oversold
TRIX(12,20)
-0.095
Sell
StochRSI(14)
0.000
Sell
Moving Average
Sell(4)
Neutral(0)
Buy(2)
Indicators
Value
Direction
MA5
1.542
Sell
MA10
1.606
Sell
MA20
1.663
Sell
MA50
1.489
Sell
MA100
1.037
Buy
MA200
0.915
Buy

Institutional Confidence

Currency: USD Updated: 2025-11-03

The company’s current institutional recognition score is 5.00, which is lower than the Biotechnology & Medical Research industry's average of 5.15. The latest institutional shareholding proportion is 68.42%, representing a quarter-over-quarter decrease of 14.13%. The largest institutional shareholder is The Vanguard, holding a total of 1.60M shares, representing 2.99% of shares outstanding, with 16.45% decrease in holdings.

Score

Industry at a Glance

Previous score
5.00
Change
0

Institutional Shareholding

No Data

Shareholder Activity

Name
Shares Held
Chg %
VenBio Partners LLC
9.70M
--
HBM Partners AG
4.50M
+31.31%
Redmile Group, LLC
3.39M
-6.85%
Millennium Management LLC
492.61K
-47.82%
Tang Capital Management, LLC
3.16M
--
Lightstone Ventures, L.P.
2.95M
--
Almitas Capital LLC
2.54M
+87.59%
The Vanguard Group, Inc.
Star Investors
1.60M
-12.90%
Acadian Asset Management LLC
1.27M
-2.19%
Two Sigma Investments, LP
1.18M
-3.47%
1
2

Risk Assessment

Currency: USD Updated: 2025-11-03

The company’s current risk assessment score is 1.50, which is lower than the Biotechnology & Medical Research industry's average of 3.47. The company's beta value is 1.24. This indicates that the stock tends to outperform the index during upward trending markets but experiences larger declines during downward trending markets.

Score

Industry at a Glance

Previous score
1.50
Change
0
Beta vs S&P 500 index
0.53
VaR
+9.41%
240-Day Maximum Drawdown
+78.30%
240-Day Volatility
+116.58%

Return

Best Daily Return
60 days
+50.69%
120 days
+50.69%
5 years
+56.13%
Worst Daily Return
60 days
-15.46%
120 days
-15.46%
5 years
-41.67%
Sharpe Ratio
60 days
+2.74
120 days
+2.59
5 years
-0.36

Risk Assessment

Maximum Drawdown
240 days
+78.30%
3 years
+97.69%
5 years
+99.54%
Return-to-Drawdown Ratio
240 days
+0.28
3 years
-0.28
5 years
-0.20
Skewness
240 days
+1.46
3 years
+1.49
5 years
+1.12

Volatility

Realised Volatility
240 days
+116.58%
5 years
+101.38%
Standardised True Range
240 days
+7.13%
5 years
+84.45%
Downside Risk-Adjusted Return
120 days
+610.99%
240 days
+610.99%
Maximum Daily Upside Volatility
60 days
+158.18%
Maximum Daily Downside Volatility
60 days
+79.28%

Liquidity

Average Turnover Rate
60 days
+1.75%
120 days
+1.37%
5 years
--
Turnover Deviation
20 days
+58.98%
60 days
-7.63%
120 days
-27.71%

Peer Comparison

Biotechnology & Medical Research
ALX Oncology Holdings Inc
ALX Oncology Holdings Inc
ALXO
6.16 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Zymeworks Inc
Zymeworks Inc
ZYME
8.55 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
CytomX Therapeutics Inc
CytomX Therapeutics Inc
CTMX
8.51 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Insmed Inc
Insmed Inc
INSM
8.49 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
NewAmsterdam Pharma Company NV
NewAmsterdam Pharma Company NV
NAMS
8.49 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Amicus Therapeutics Inc
Amicus Therapeutics Inc
FOLD
8.47 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
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