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AC Immune SA

ACIU
3.180USD
0.000
Close 12/22, 16:00ETQuotes delayed by 15 min
319.30MMarket Cap
LossP/E TTM

AC Immune SA

3.180
0.000
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of AC Immune SA

Currency: USD Updated: 2025-12-22

Key Insights

AC Immune SA's fundamentals are relatively stable, and its growth potential is good.Its valuation is considered fairly valued, ranking 156/404 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Strong Buy, with the highest price target at 9.00.In the medium term, the stock price is expected to trend up.Despite an average stock market performance over the past month, the company shows strong technicals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

AC Immune SA's Score

Industry at a Glance

Industry Ranking
156 / 404
Overall Ranking
279 / 4578
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Analyst Rating

Based on 3 analysts
Strong Buy
Current Rating
9.000
Target Price
+223.74%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

AC Immune SA Highlights

StrengthsRisks
AC Immune SA is a Switzerland-based clinical-stage biopharmaceutical company. The Company focuses on precision medicine for neurodegenerative diseases. It designs, discovers and develops therapeutic, as well as diagnostic products for prevention, diagnosis and treatment of diseases caused by misfolding proteins. Its SupraAntigen and Morphomer technology platforms to create antibodies, small molecules and vaccines designed to address a broad range of neurodegenerative indications, such as Alzheimer's disease (AD). The Company's pipeline includes nine therapeutic product candidates with five in clinical trials, and three diagnostic candidates. Its lead product candidate is Crenezumab, a humanized and monoclonal anti-Abeta antibody for Alzheimer’s disease. It has collaborations with pharmaceutical companies, including Roche/Genentech, Eli Lilly, Biogen, Janssen Pharmaceuticals, Nestle Institute of Health Sciences, Life Molecular Imaging (formerly Piramal Imaging) and Essex Bio-Technology.
High Growth
The company's revenue has grown steadily over the past 3 years, averaging 631.15% year-on-year.
Growing
The company is in a growing phase, with the latest annual income totaling USD 30.97M.
Fairly Valued
The company’s latest PE is -3.54, at a medium 3-year percentile range.
Institutional Buying
The latest institutional holdings are 24.95M shares, increasing 0.03% quarter-over-quarter.
Held by Invesco
Star Investor Invesco holds 4.76K shares of this stock.

Financial Health

Currency: USD Updated: 2025-12-22

The current financial score of AC Immune SA is 5.18, ranking 391/404 in the Biotechnology & Medical Research industry. Its financial status is weak, and its operating efficiency is low. Its latest quarterly revenue reached 1.16M, representing a year-over-year decrease of 96.08%, while its net profit experienced a year-over-year decrease of 406.91%.

Score

Industry at a Glance

Previous score
5.18
Change
0

Financials

4.98

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

7.83

Operational Efficiency

2.83

Growth Potential

3.16

Shareholder Returns

7.07

AC Immune SA's Company Valuation

Currency: USD Updated: 2025-12-22

The current valuation score of AC Immune SA is 5.95, ranking 361/404 in the Biotechnology & Medical Research industry. Its current P/E ratio is -3.54, which is -42.42% below the recent high of -2.04 and -123.56% above the recent low of -7.91.

Score

Industry at a Glance

Previous score
5.95
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 156/404
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2025-12-22

The current earnings forecast score of AC Immune SA is 9.33, ranking 5/404 in the Biotechnology & Medical Research industry. The average price target for AC Immune SA is 8.50, with a high of 12.00 and a low of 7.00.

Score

Industry at a Glance

Previous score
9.33
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 3 analysts
Strong Buy
Current Rating
9.000
Target Price
+223.74%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

171
Total
6
Median
8
Average
Company name
Ratings
Analysts
AC Immune SA
ACIU
3
Biogen Inc
BIIB
36
Amgen Inc
AMGN
35
Eli Lilly and Co
LLY
33
Vertex Pharmaceuticals Inc
VRTX
33
AbbVie Inc
ABBV
32
1
2
3
...
34

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2025-12-22

The current price momentum score of AC Immune SA is 7.45, ranking 116/404 in the Biotechnology & Medical Research industry. Currently, the stock price is trading between the resistance level at 3.81 and the support level at 2.55, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
7.24
Change
0.21

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(1)
Neutral(5)
Buy(1)
Indicators
Value
Direction
MACD(12,26,9)
0.063
Neutral
RSI(14)
54.361
Neutral
STOCH(KDJ)(9,3,3)
44.637
Neutral
ATR(14)
0.322
High Vlolatility
CCI(14)
52.362
Neutral
Williams %R
49.206
Neutral
TRIX(12,20)
-0.077
Sell
StochRSI(14)
65.639
Buy
Moving Average
Sell(0)
Neutral(0)
Buy(6)
Indicators
Value
Direction
MA5
3.078
Buy
MA10
3.033
Buy
MA20
2.952
Buy
MA50
3.102
Buy
MA100
2.801
Buy
MA200
2.348
Buy

Institutional Confidence

Currency: USD Updated: 2025-12-22

The current institutional shareholding score of AC Immune SA is 3.00, ranking 197/404 in the Biotechnology & Medical Research industry. The latest institutional shareholding proportion is 29.05%, representing a quarter-over-quarter decrease of 0.04%. The largest institutional shareholder is James Simons, holding a total of 770.42K shares, representing 0.77% of shares outstanding, with 4.11% decrease in holdings.

Score

Industry at a Glance

Previous score
3.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
BVF Partners L.P.
19.82M
--
DH Capital GmbH & Co. KG
16.32M
--
Varuma AG
12.00M
--
Affiris AG
6.43M
-2.28%
Pfeifer (Andrea M. A Ph.D.)
2.96M
+22.09%
Wells Fargo Advisors
1.02M
+2.71%
Millennium Management LLC
291.53K
+37.03%
Renaissance Technologies LLC
Star Investors
828.32K
+3.09%
Acadian Asset Management LLC
411.70K
+10.92%
BlackRock Institutional Trust Company, N.A.
363.80K
-7.55%
1
2

Risk Assessment

Currency: USD Updated: 2025-12-22

The current risk assessment score of AC Immune SA is 2.32, ranking 253/404 in the Biotechnology & Medical Research industry. The company's beta value is 1.62. This indicates that the stock tends to outperform the index during upward trending markets but experiences larger declines during downward trending markets.

Score

Industry at a Glance

Previous score
2.32
Change
0
Beta vs S&P 500 index
1.62
VaR
+6.44%
240-Day Maximum Drawdown
+49.49%
240-Day Volatility
+86.42%

Return

Best Daily Return
60 days
+27.48%
120 days
+27.48%
5 years
+71.72%
Worst Daily Return
60 days
-11.98%
120 days
-11.98%
5 years
-19.18%
Sharpe Ratio
60 days
+0.85
120 days
+1.54
5 years
+0.13

Risk Assessment

Maximum Drawdown
240 days
+49.49%
3 years
+70.40%
5 years
+82.32%
Return-to-Drawdown Ratio
240 days
+0.17
3 years
+0.16
5 years
-0.15
Skewness
240 days
+1.28
3 years
+4.73
5 years
+3.54

Volatility

Realised Volatility
240 days
+86.42%
5 years
+88.74%
Standardised True Range
240 days
+5.77%
5 years
+7.67%
Downside Risk-Adjusted Return
120 days
+274.55%
240 days
+274.55%
Maximum Daily Upside Volatility
60 days
+96.41%
Maximum Daily Downside Volatility
60 days
+57.70%

Liquidity

Average Turnover Rate
60 days
+0.13%
120 days
+0.14%
5 years
--
Turnover Deviation
20 days
-53.52%
60 days
-43.85%
120 days
-38.73%

Peer Comparison

Biotechnology & Medical Research
AC Immune SA
AC Immune SA
ACIU
6.08 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Amicus Therapeutics Inc
Amicus Therapeutics Inc
FOLD
8.80 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Krystal Biotech Inc
Krystal Biotech Inc
KRYS
8.47 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Charles River Laboratories International Inc
Charles River Laboratories International Inc
CRL
8.43 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Madrigal Pharmaceuticals Inc
Madrigal Pharmaceuticals Inc
MDGL
8.40 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
IQVIA Holdings Inc
IQVIA Holdings Inc
IQV
8.39 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
View more

FAQs

How does TradingKey generate the Stock Score of AC Immune SA?

The TradingKey Stock Score provides a comprehensive assessment of AC Immune SA based on 34 indicators derived from over 100 underlying data points.
These indicators are categorised into six key dimensions: financial health, company profile, earnings forecasts, price momentum, institutional confidence, and risk assessment, collectively providing investors with a thorough analysis of AC Immune SA’s performance and outlook.

How do we generate the financial health score of AC Immune SA?

To generate the financial health score of AC Immune SA, we analyse various key financial indicators across several core dimensions, including financial fundamentals, earnings quality, operational efficiency, growth potential, and shareholder returns.
By integrating these comprehensive data, the financial health score not only reflects AC Immune SA's overall stability, operational efficiency, and growth potential but also captures the investment returns delivered to shareholders. This score aims to support rational decision-making for investors and other stakeholders. A higher score indicates a better financial health of AC Immune SA.

How do we generate the company valuation score of AC Immune SA?

To generate the company valuation score of AC Immune SA, we use several key financial ratios, including P/E, P/B, P/S, and P/CF. These metrics compare AC Immune SA’s market value to its earnings, assets, sales, and cash flow, serving as core indicators for assessing company value.
By analysing these ratios in an all-round manner, the valuation score reflects not only the market’s current perception of AC Immune SA’s value but also its future profitability and growth potential, thereby supporting more informed investment decisions. A higher score indicates a fairer valuation of AC Immune SA.

How do we generate the earnings forecast score of AC Immune SA?

To calculate the earnings forecast score of AC Immune SA, we consider various key indicators such as analyst ratings, financial forecasts, support and resistance levels, and peer comparisons:
Current ratings and price targets directly reflect analysts’ expectations, while the upside space indicates their views on the stock’s growth potential.
Financial metrics like earnings per share (EPS), revenue, net income, and earnings before interest and taxes (EBIT) are core measures for assessing profitability.
By analysing the high, median, and low ranges of the target price, we can identify price trends and determine key support and resistance levels.
Comparing these indicators against peers provides context for the stock’s performance and helps anchor more realistic expectations.
These factors together form a comprehensive earnings forecast score that accurately reflects the stock’s expected financial performance and growth potential. A higher score suggests that analysts have a more optimistic outlook on AC Immune SA’s future.

How do we generate the price momentum score of AC Immune SA?

When generating the price momentum score for AC Immune SA, we examine momentum indicators including support and resistance levels as well as volume metrics.
Support levels represent price points where buying interest is strong enough to prevent further declines, while resistance levels indicate prices where selling pressure may hinder upward movement. By analysing typical price volume alongside total volume, we assess overall market activity and liquidity. These indicators help identify price trends and potential shifts, enabling more accurate predictions of future earnings.
This comprehensive approach can reflect market sentiment and enable rational forecasts of AC Immune SA’s prices. A higher score indicates a more stable short-term price trend for AC Immune SA.

How do we generate the institutional confidence score of AC Immune SA?

To generate the institutional confidence score of AC Immune SA, we analyse both the proportion of shares held by institutions and the number of shares they own. A higher institutional ownership percentage indicates strong confidence of professional investors, which is generally a positive signal about AC Immune SA’s potential. By examining the number of shares held, we gain deeper insight into institutions’ commitment and attitude toward the stock, as institutional investors typically conduct thorough analysis before making investment decisions. Understanding institutional confidence helps us refine earnings forecasts and provides a more reliable perspective on the company’s future performance and market stability. A higher score indicates greater institutional endorsement of AC Immune SA.

How do we generate the risk management score of AC Immune SA?

To assess the risk management score of AC Immune SA, we examine multiple key indicators related to returns, risk, volatility, and liquidity.
The highest and lowest daily returns reflect the potential size of gains and losses, while the Sharpe ratio measures risk-adjusted return performance. On the risk side, we analyse maximum drawdown and the return-to-drawdown ratio to identify extreme loss scenarios. Skewness helps assess the distribution of returns and whether performance may be biased. Volatility indicators—such as realised volatility and standardised true range—reveal price fluctuations. Downside risk-adjusted returns provide insight into potential losses and gains. Lastly, liquidity metrics like average turnover rate and turnover deviation indicate how actively the stock is traded.
These indicators together provide a multi-dimensional understanding of AC Immune SA’s risk-return profile, serving as core factors of the risk management score. A higher score indicates lower risk on the side of AC Immune SA.
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