Boundless Bio, Inc. is a clinical-stage oncology company, which is engaged in cancer therapeutics that addresses the unmet need in patients with oncogene amplified tumors by targeting extrachromosomal DNA (ecDNA). Using its proprietary Spyglass platform, it identifies targets essential for ecDNA functionality in oncogene amplified cancer cells, then designs and develops small molecule drugs called ecDNA-directed therapeutic candidates (ecDTx) to inhibit those targets. Its lead ecDTx, BBI-355, is an oral, selective inhibitor of checkpoint kinase 1 (CHK1), which manages ecDNA replication and transcription in cancer cells. BBI-355 demonstrated CHK1 inhibition and tumor regressions in ecDNA-enabled preclinical cancer models and is being studied in a first-in-human, Phase I/II clinical trial in patients with oncogene amplified cancers. Its second ecDTx, BBI-825, is an oral, selective inhibitor of ribonucleotide reductase, which is essential for ecDNA assembly and repair in cancer cells.
종목 코드 BOLD
회사 이름Boundless Bio Inc
상장일Mar 28, 2024
CEOMr. Zachary D. Hornby
직원 수64
유형Ordinary Share
회계 연도 종료Mar 28
주소10955 Alexandria Way
도시SAN DIEGO
증권 거래소NASDAQ Global Select Consolidated
국가United States of America
우편 번호92121
전화18587669912
웹사이트https://boundlessbio.com/
종목 코드 BOLD
상장일Mar 28, 2024
CEOMr. Zachary D. Hornby
지난 5년 동안 총
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