U.S. STOCKS ON THE MOVE-Eli Lilly, Space stocks, Anixa Biosciences

April 1 (Reuters) - Wall Street's main indexes rose on Wednesday, building onto their biggest one-day gains in nearly a year, after President Donald Trump's comments suggested an end to the Middle East conflict could be close. .N

At 13:30 EDT, the Dow Jones Industrial Average .DJI was up 0.98% at 46,793.40. The S&P 500 .SPX was up 1.21% at 6,607.83, and the Nasdaq Composite .IXIC was up 1.74% at 21,965.36.

The top three S&P 500 .PG.INX percentage gainers:

Western Digital Corp WDC.OQ, up 12.0%

Sandisk Corp SNDK.OQ, up 11.5%

Lumentum Holdings Inc LITE.OQ, up 11.3%

The top three S&P 500 .PL.INX percentage losers:

Nike Inc NKE.N, down 14.1%

LyondellBasell Industries NV LYB.N, down 7.6%

Texas Pacific Land Corp TPL.N, down 6.7%

The top three NYSE .PG.N percentage gainers:

System1 Inc SST.N, up 40.1%

Local Bounti Corp LOCL.N, up 28.4%

agilon health inc AGL.N, up 21.1%

The top three NYSE .PL.N percentage losers:

RH RH.N, down 21.9%

Turning Point Brands Inc TPB.N, down 16.5%

Nike Inc NKE.N, down 14.1%

The top three Nasdaq .PG.O percentage gainers:

Cyclerion Therapeutics Inc CYCN.OQ, up 328.7%

Axe Compute Inc AGPU.OQ, up 103.1%

U Power Ltd UCAR.OQ, up 73.1%

The top three Nasdaq .PL.O percentage losers:

Neo-Concept International Group Holdings Ltd NCI.OQ, down 57.0%

Linkers Industries Ltd LNKS.OQ, down 46.2%

U-BX Technology Ltd UBXG.OQ, down 37.1%

Blackstone Inc BX.N:

BUZZ - Gambling firm Cirsa drops after Blackstone sells part of its stake nL8N40K0F5

Nike Inc NKE.N:

BUZZ - Slides as China lag, inventory weigh on forecast, results nL6N40K132

nCino Inc NCNO.O:

BUZZ - Shares jump on quarterly revenue beat, strong outlook nL4N40K1A0

BRC Group Holdings Inc RILY.O:

BUZZ - Climbs after Q4 profit, revenue jump nL6N40K0N4

Exxon Mobil Corp XOM.N:

Chevron Corp CVX.N:

ConocoPhillips COP.N:

Occidental Petroleum Corp OXY.N:

BUZZ - US energy stocks decline as crude prices weaken nL4N40K1CI

Beyond Meat Inc BYND.O:

BUZZ - Shares fall as demand weakens and losses grow nL6N40K0ED

Newmont Corp NEM.N:

Gold Fields Ltd GFI.N:

AngloGold Ashanti PLC AU.N:

Harmony Gold Mining Co Ltd HMY.N:

BUZZ - Gold miners gain as bullion rises on weaker dollar nL4N40K0R0

Immunic Inc IMUX.O:

BUZZ - Rises as regains Nasdaq listing compliance nL4N40K0TK

Zymeworks Inc ZYME.O:

BUZZ - Rises after naming new CFO nL4N40K1V5

RH RH.N:

BUZZ - Slides after downbeat forecast; Jefferies cuts PT nL6N40K0QS

Service Properties Trust SVC.O:

BUZZ - Shares collapse on $500 mln equity raise nL6N40K0SY

Quanta Services Inc PWR.N:

BUZZ - Bernstein raises Quanta Services PT on strong growth potential nL4N40K0U2

Seagate Technology Holdings PLC STX.O:

BUZZ - Rises after Bernstein hikes price target nL4N40K0WG

Honeywell International Inc HON.O:

BUZZ - Barclays slashes Honeywell PT on geopolitical risks nL4N40K0WS

Ocugen Inc OCGN.O:

BUZZ - Rises after finishing patient dosing in late-stage eye gene therapy trial nL4N40K0X0

Rio Tinto PLC RIO.N:

BHP Group Ltd BHP.N:

Southern Copper Corp SCCO.N:

Freeport-McMoRan Inc FCX.N:

BUZZ - Copper miners rise as red metal touches two-week high nL4N40K1CK

Cal-Maine Foods Inc CALM.O:

BUZZ - Rises after third-quarter sales, profit beat estimates nL6N40K0RY

Cyclerion Therapeutics Inc CYCN.O:

BUZZ - More than quadruples on merger deal with Korsana nL4N40K19C

Axsome Therapeutics Inc AXSM.O:

BUZZ - Rises as it buys rights to experimental schizophrenia drug nL4N40K0XS

Snap Inc SNAP.N:

BUZZ - Rosenblatt says finding partner for Snap's smart glasses unit tough nL4N40K0W7

NewcelX AG NCEL.O:

BUZZ - Rises after raising funds at premium to boost diabetes program nL4N40K0YA

Alkermes PLC ALKS.O:

BUZZ - Rises as it starts late-stage trials of sleep disorder drug nL4N40K0WF

Deere & Co DE.N:

BUZZ - Barclays lifts PT on Deere, cites inventory progress nL4N40K108

Zai Lab Ltd ZLAB.O:

BUZZ - Rises as it teams up with Amgen for lung cancer drug trial nL4N40K100

Walt Disney Co DIS.N:

BUZZ - Raymond James upgrades Disney to "outperform"; shares rise nL4N40K10H

Western Digital Corp WDC.O:

Sandisk Corp SNDK.O:

Micron Technology Inc MU.O:

BUZZ - Memory stocks extend Tuesday's gains after Bernstein upgrade nL4N40K196

Nano-X Imaging Ltd NNOX.O:

BUZZ - Rises on U.S. distribution deal to expand its 3D imaging system nL4N40K11P

Nuvation Bio Inc NUVB.N:

BUZZ - Rises after securing Japan rights to brain cancer drug nL4N40K11K

Realty Income Corp O.N:

BUZZ - Deutsche Bank raises PT on Realty Income citing benefits from AI tool use nL4N40K11D

Maxeon Solar Technologies Ltd MAXN.O:

BUZZ - Falls after filing for judicial management in Singapore nL4N40K0YW

Rivian Automotive Inc RIVN.O:

BUZZ - Up as DA Davidson upgrades stock after recent slide nL6N40K0WL

Terex Corp TEX.N:

BUZZ - Barclays reinstates Terex coverage with 'overweight' rating nL4N40K11J

Janux Therapeutics Inc JANX.O:

BUZZ - Up after nominating cancer therapy in Bristol Myers deal nL4N40K12D

Hasbro Inc HAS.O:

BUZZ - Slips after cybersecurity incident disclosure nL6N40K0WX

Conagra Brands Inc CAG.N:

BUZZ - Down after weak annual profit forecast nL6N40K0XO

CBRE Group Inc CBRE.N:

BUZZ - J.P. Morgan cuts CBRE Group's PT on slower growth nL4N40K13X

Beyond Air Inc XAIR.O:

BUZZ - Rises as it secures national hospital purchasing deal nL4N40K161

Target Hospitality Corp TH.O:

BUZZ - Soars on $550 mln data center contract, annual outlook boost nL6N40K0XY

Intel Corp INTC.O:

BUZZ - Climbs as chipmaker plans to buy back Apollo stake in Ireland plant nL6N40K101

Eaton Corporation PLC ETN.N:

BUZZ - Barclays cuts Eaton's PT on weak growth expectations nL4N40K160

Lexaria Bioscience Corp LEXX.O:

BUZZ - To begin oral weight‑loss drug study; shares up nL4N40K174

Merit Medical Systems Inc MMSI.O:

BUZZ - Rises as it buys cancer tissue marker maker View Point nL4N40K190

Avery Dennison Corp AVY.N:

Packaging Corp of America PKG.N:

International Paper Co IP.N:

Ball Corp BALL.N:

BUZZ - Deutsche Bank initiates coverage on U.S. packaging firms nL4N40K18W

Procure Space ETF UFO.O:

BUZZ - Surges ahead of SpaceX's closely watched IPO filing nL6N40K10O

HMH Holding Inc HMH.O:

BUZZ - Baker Hughes venture HMH on track for muted Nasdaq debut nL6N40K11N

Philip Morris International Inc PM.N:

Turning Point Brands Inc TPB.N:

Altria Group Inc MO.N:

BUZZ - Tobacco stocks fall after Reuters reports on delays to US nicotine pouch fast-track scheme nL6N40K11G

Tempus AI Inc TEM.O:

BUZZ - Rises after study shows AI-driven alerts improve heart valve treatment nL4N40K1F9

Aureus Greenway Holdings Inc AGH.O:

BUZZ - Rises; drone firm Powerus reportedly pitching UAE on weapons deal nL6N40K12T

Boeing Co BA.N:

BUZZ - Rises after Pentagon deal to boost production of PAC-3 MSE seekers nL4N40K1G1

Eli Lilly and Co LLY.N:

BUZZ - Rises after US FDA approves weight-loss pill nL4N40K1MQ

Intuitive Machines Inc LUNR.O:

Howmet Aerospace Inc HWM.N:

EchoStar Corp SATS.O:

Destiny Tech100 Inc DXYZ.N:

BUZZ - Space stocks rise after report of Musk's SpaceX confidentially filing for US IPO nL4N40K1K4

Anixa Biosciences Inc ANIX.O:

BUZZ - Climbs after breast cancer vaccine moves to mid-stage trial nL4N40K1I1