
Shares of Crinetics Pharmaceuticals CRNX.O up 19.8% at $56.01 premarket after reporting over $5 million in Q4 preliminary 2025 net product rev from recently launched Palsonify
Palsonify approved in September 2025 for treating acromegaly, showing strong early sales and broad doctor adoption
Company also reports positive Phase 2 study of atumelnant, an experimental oral drug aiming to treat rare hormone disorders by blocking a hormone receptor to balance hormone levels
CEO Scott Struthers highlights broad prescriber base, favorable payer coverage, and over 200 enrollment forms in first three months post-approval
CRNX stock up 0.39% this year after dropping 9% in 2025