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Weight-loss drug frenzy powers Lilly for ninth straight annual rise

ReutersDec 31, 2025 12:01 PM

Shares of Eli Lilly LLY.N have risen nearly 40% this year - set for the ninth successive year of gains

The world's most valuable healthcare company joined the trillion dollar club last month

U.S.-listed stock of rival Novo Nordisk NOVOb.CO in comparison has declined 40% this year, set for its second year in red

Investors are focused on the potential approval and launch of LLY's oral GLP-1 drug orforglipron for 2026

Novo's Wegovy pill and LLY's orforglipron must drive accelerated demand to justify the willingness to lower pricing not only within government's Medicare and Medicaid programs, but also in the cash pay obesity market, brokerage Guggenheim said in a note earlier this month

Despite anticipated price changes, brokerage forecasts 20% overall sales growth to $76.8 billion in 2026 for Lilly, driven primarily by diabetes drug Mounjaro and Zepbound for obesity with incremental growth coming from launch of the pill

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