
Analysts see limited impact on Eli Lilly LLY.N after Danish rival Novo Nordisk's NOVOb.CO closely watched Alzheimer's trials failed to hit the mark
The older oral version of Novo's GLP-1 drug, Rybelsus, failed to help slow progression of the brain-wasting disease in late-stage trials
Lilly's blockbuster weight-loss drug, Zepbound, and Novo's rival drug, Wegovy, also target the appetite-suppressing GLP-1 hormone
Cantor analyst Carter Gould noted that the trial failure shouldn't come as a surprise and that LLY had never pursued a similar strategy and "had only recently moved forward with pursuing neuro indications with their own GLP-1 – and even then had focused on addictions (opioids, alcohol)"
"Though Lilly would have quickly moved an asset (possibly brenipatide; oral GLP-1/GIP agonist) into AD studies had evoke/+ provided some sort of a positive signal, today's failure reads like it has little room for interpretation," Citi analyst Geoff Meacham said
Up to last close, Lilly's shares have gained 37.3% YTD