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U.S. STOCKS ON THE MOVE-Oruka Therapeutics, Regeneron, natgas companies

ReutersSep 17, 2025 3:47 PM
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Wall Street's main indexes were mixed in choppy trading on Wednesday, with the S&P 500 muted ahead of a widely expected interest-rate cut from the U.S. Federal Reserve later in the day. .N

At 11:30 EDT, the Dow Jones Industrial Average .DJI was up 0.63% at 46,047.84. The S&P 500 .SPX was down 0.14% at 6,597.24, and the Nasdaq Composite .IXIC was down 0.53% at 22,215.08.

The top three S&P 500 .PG.INX percentage gainers:

Workday Inc WDAY.OQ, up 8.4%

Charter Communications Inc CHTR.OQ, up 3.5%

Dollar Tree Inc DLTR.OQ, up 3.2%

The top three S&P 500 .PL.INX percentage losers:

Uber Technologies Inc UBER.N, down 5.2%

Insulet Corp PODD.OQ, down 3.4%

Broadcom Inc AVGO.OQ, down 3.4%

The top three NYSE .PG.N percentage gainers:

Generation Essentials Group TGE.N, up 22.4%

Offerpad Solutions Inc OPAD.N, up 17.9%

Local Bounti Corp LOCL.N, up 16.5%

The top three NYSE .PL.N percentage losers:

Paramount Group Inc PGRE.N, down 11.6%

Redwire Corp RDW.N, down 11.1%

Mogu Inc MOGU.N, down 10.0%

The top three Nasdaq .PG.O percentage gainers:

Scisparc Ltd SPRC.OQ, up 129.1%

Visionary Holdings Inc GV.OQ, up 80.6%

CDT Equity Inc CDT.OQ, up 35.7%

The top three Nasdaq .PL.O percentage losers:

bioAffinity Technologies Inc BIAF.OQ, down 32.0%

Boxlight Corp BOXL.OQ, down 31.3%

Enveric Biosciences Inc ENVB.OQ, down 28.4%

Baidu Inc :
BUZZ - Hong Kong shares climb most in 3 years on AI progress; Jefferies lifts PT nL2N3V405K

Novo Nordisk A/S :
BUZZ - Berenberg sees opportunity for pharma cos despite policy risks; upgrades Novo nL5N3V40C0

Nvidia Corp :
BUZZ - Slips on report China asks tech firms to halt buying company's AI chips nL3N3V40YH

New Fortress Energy Inc :
BUZZ - Gains on LNG supply deal with Puerto Rico government nL3N3V40YJ

Workday Inc :
BUZZ - Rises after Elliott backs leadership, builds more than $2 billion stake nL3N3V40Y6

Newmont Corp :

Gold Fields Ltd :

Harmony Gold Mining Co Ltd ::

AngloGold Ashanti PLC :

BUZZ -Gold miners down as bullion prices edge lower ahead of Fed rate verdict nL3N3V40LZ

Alibaba.com Ltd :

Pinduoduo Inc :

Bilibili Inc :

Nio Inc :

BUZZ - U.S.-listed shares of Chinese firms rise as local markets rally nL3N3V4113

Teck Resources Ltd :

BUZZ - TD Cowen raises Teck Resources' PT on optimism around future JV, potential merger with Anglo nL3N3V40M6

Eli Lilly and Co :
BUZZ - Berenberg downgrades Eli Lilly to "hold" as obesity drug expectations soar nL6N3V40D6

Schlumberger NV :
BUZZ - Zephirin Group cuts SLB PT on share dilution from ChampionX deal nL3N3V40NI

Carrier Global Corp :
BUZZ - Oppenheimer cuts Carrier's PT on weaker US residential HVAC demand nL3N3V40OT

Diversified Energy Company PLC :
BUZZ - Slides on pricing $79 mln secondary offering nL6N3V40HP

Ormat Technologies Inc :
BUZZ - Piper Sandler upgrades Ormat's rating to 'overweight' as geothermal demand rises nL6N3V40I6

Hecla Mining Co HL.N>:

Coeur Mining Inc :

Endeavour Silver Corp :

Silvercorp Metals Inc :

BUZZ - Silver miners down as white metal's prices slip ahead of Fed rate decision nL3N3V40QB

Manchester United PLC :
BUZZ - Shares fall as soccer club posts sixth consecutive annual loss nL3N3V40YR

Cytokinetics Inc :
BUZZ - Rises after upsized $650 mln convertible bonds sale nL6N3V40IL

Roivant Sciences Ltd :
BUZZ - Rises after positive trial data for muscle-and-skin disease drug nL3N3V40YF

X4 Pharmaceuticals Inc :
BUZZ - To cut workforce by half, shares up nL3N3V40R9

Pebblebrook Hotel Trust :
BUZZ - Drops after pricing $350 mln convertible debt deal nL6N3V40JB

General Mills Inc :
BUZZ - Slips on unchanged annual forecasts nL3N3V40RW

Paramount Group Inc :
BUZZ - Falls after Rithm Capital agrees to buy co for $1.6 bln nL3N3V40SM

Forward Industries Inc :
BUZZ - In reverse after $4 bln stock sale plans announced nL6N3V40KL

Rio Tinto PLC :

BHP Group Ltd :

Southern Copper Corp :

Freeport-McMoRan Inc :

BUZZ - Copper miners fall as red metal hits one-week low ahead of Fed rates call nL3N3V40UK

Lyft Inc :
BUZZ - Gains after partnering with Waymo to launch autonomous ride-hailing in 2026 nL3N3V40XE

Union Pacific Corp :
BUZZ - TD Cowen lifts Union Pacific's PT on merger synergies in watershed region nL3N3V40YS

Oruka Therapeutics Inc :
BUZZ - Jumps after positive early-stage study data for psoriasis drug nL3N3V40Z4

CNX Resources Corp :

Williams Companies Inc :

Sempra :

United States Natural Gas Fund LP :

BUZZ - Natgas companies gain on lower output, higher demand forecasts nL3N3V40Z1

Regeneron Pharmaceuticals Inc :
BUZZ - Climbs as bone disorder drug succeeds in late-stage trial nL3N3V410P

Adtran Holdings Inc :
BUZZ - Falls after boosted $175 mln convertible bonds sale nL6N3V40NN

Progressive Corp :
BUZZ - Falls as BMO cuts to 'market perform' on tighter competition nL6N3V40MU

Index RIC

Index name

Percent change %

.SPX

S&P 500

-0.14

.SPLRCT

S&P 500 Information Technology

-0.83

.SPLRCU

S&P 500 Utilities

0.76

.SPLRCD

S&P 500 Consumer Discretionary

-0.7

.SPLRCM

S&P 500 Materials

0.67

.SPLRCI

S&P 500 Industrials

-0.08

.SPLRCL

S&P 500 Communication Services (Sector)

-0.63

.SPSY

S&P 500 Financials

0.9

.SPLRCR

S&P 500 Real Estate

0.89

.SPXHC

S&P 500 Health Care

0.67

.SPLRCS

S&P 500 Consumer Staples

1.19

.SPNY

S&P 500 Energy

-0.02

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