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Lyell Immunopharma misses Q4 revenue estimates

ReutersMar 12, 2026 9:12 PM


Overview

  • CAR T-cell therapy developer's Q4 revenue missed analyst expectations

  • Adjusted net loss for Q4 was narrower than expected, beating analyst estimates

  • Company closed $50 mln equity tranche after achieving clinical milestone for ronde-cel


Outlook

  • Company expects current cash to fund operations into Q2 2027 through multiple clinical milestones


Result Drivers

  • Cash, cash equivalents and marketable securities as of December 31, 2025 were approximately $247.2 million

  • ACQUISITION-RELATED EXPENSES - Q4 net loss included $66.3 mln in acquired in-process R&D expense and $19.7 mln in stock-based compensation tied to LYL273 license acquisition

  • COST REDUCTIONS - Lower personnel and facility costs following workforce reduction and technology transfer of ronde-cel partially offset higher R&D expenses


Company press release: ID:nGNX7rqRn7


Key Details

Metric

Beat/Miss

Actual

Consensus Estimate

Q4 Revenue

Miss

$6,000

$12,200 (5 Analysts)

Q4 Adjusted Net Income

Beat

-$33.06 mln

-$47.67 mln (4 Analysts)

Q4 Net Income

-$140.72 mln

Q4 Operating Expenses

$127.65 mln

Q4 Operating Income

-$127.64 mln


Analyst Coverage

  • The current average analyst rating on the shares is "buy" and the breakdown of recommendations is 3 "strong buy" or "buy", no "hold" and 1 "sell" or "strong sell"

  • The average consensus recommendation for the biotechnology & medical research peer group is "buy"

  • Wall Street's median 12-month price target for Lyell Immunopharma Inc is $34.00, about 35.2% above its March 11 closing price of $25.14


For questions concerning the data in this report, contact Estimates.Support@lseg.com. For any other questions or feedback, contact reuters.support@thomsonreuters.com.

Disclaimer: The information provided on this website is for educational and informational purposes only and should not be considered financial or investment advice.
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