FACTBOX-Widely used drugs on US imports list from Europe
March 18 (Reuters) - Widely used prescription medicines could get caught up in the Trump administration's tariff trade wars and EU retaliation.
The following is a list of major prescription drugs whose ingredients or components are imported into the United States from the European Union, based on U.S. Food and Drug Administration import data from 2023 and 2024.
Company | Brand Name (chemical name) | Used to Treat | Country of Import | Company Comments |
AbbVie ABBV.N | Rinvoq (upadacitinib) | rheumatoid arthritis | Germany, Ireland | Abbvie declined to comment on specific production or import sites for its drugs. The company said it "maintains a robust, diversified and redundant manufacturing network with geographic balance and multiple supply sites" |
Norvir (ritonavir) | HIV | Germany | ||
Humira (adalimumab) | rheumatoid arthritis, psoriatic arthiritis, others | Germany | ||
Amgen AMGN.O | Blincyto (blinatumomab) | A type of acute lymphoblastic leukemia | Netherlands | |
Prolia/Xgeva (denosumab) | osteoporosis, preventing fractures from cancer in bones | Netherlands | ||
Bavarian Nordic A/S BAVA.CO | Jynneos | smallpox vaccine, also used for mpox | Denmark | Bavarian Nordic said it manufactures all its bulk vaccine/bulk drug substance for Jynneos in Denmark, and the fill and finish is done either at its own site in Denmark or in the U.S., depending on the markets served. |
Bristol Myers Squibb BMY.N | Eliquis (apixaban) | Blood thinner/clot preventer | Ireland | |
Opdivo (nivolumab) | cancer immunotherapy | Ireland | ||
Eli Lilly LLY.N | Mounjaro, Zepbound (tirzepatide) | type 2 diabetes, obesity | Germany, Netherlands | A Lilly spokesperson said the company prefers to source materials internally, as evidenced by its most recent manufacturing announcements. It does not disclose details of in-house vs external manufacturing |
Johnson & Johnson JNJ.N | Stelara (ustekinumab) | inflammatory bowel disease, psoriatic arthritis, other autoimmune conditions | Ireland, Netherlands | |
Invega/Invega Sustenna (paliperidone) | schizophrenia | Ireland | ||
Merck & Co MRK.N | ritonavir | antiviral | Netherlands | |
Keytruda (pembrolizumab) | cancer immunotherapy | Netherlands, Ireland | ||
Gardasil | HPV vaccine for cancer prevention | Ireland | ||
Novavax NVAX.O | Nuvaxovid | COVID-19 vaccine | Germany | Novavax said its vaccine is manufactured by The Serum Institute in India. |
Novo Nordisk NOVOb.CO | Ozempic (semaglutide ) | type 2 diabetes, | Ireland, Germany, Denmark | Novo said in a statement that it manufactures the active ingredients for its obesity and diabetes drugs in Denmark and United States only |
Wegovy (semaglutide) | obesity | Ireland, Germany | ||
Pfizer PFE.N | Prevnar family | pneumococcal vaccines for pneumonia prevention | Ireland | |
Penbraya | meningococcal meningitis vaccine | Ireland | ||
Comirnaty | COVID-19 vaccine | Ireland, Germany | ||
Eliquis (apixaban) | blood thinner/clot preventer | Netherlands | ||
Regeneron REGN.O | Eylea (aflibercept ) | Wet age-related macular degeneration, other eye conditions | Ireland | Regeneron has manufacturing facilities in both the U.S. and Ireland and is currently expanding its campus in New York. |
Roche ROG.S | Avastin (bevacizumab) | metastatic colorectal cancer, diabetic eye disease and other eye disorders | Germany | Roche declined to comment on which drug is produced where, and for which market. It said that a majority of its products cross different countries/continents across the development and supply chain. |
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