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Vyne Therapeutics Inc

VYNE
0.322USD
-0.005-1.65%
Close 11/04, 16:00ETQuotes delayed by 15 min
6.37MMarket Cap
LossP/E TTM

Vyne Therapeutics Inc

0.322
-0.005-1.65%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Vyne Therapeutics Inc

Currency: USD Updated: 2025-11-04

Key Insights

The company's fundamentals are relatively very healthy. Its valuation is considered fairly valued,and institutional recognition is very high. Over the past 30 days, multiple analysts have rated the company as a Buy. Despite a very weak stock market performance, the company shows strong fundamentals. The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Vyne Therapeutics Inc's Score

Industry at a Glance

Industry Ranking
192 / 407
Overall Ranking
327 / 4616
Industry
Biotechnology & Medical Research

Support & Resistance

No Data

Score Analysis

Current score
Previous score

Analyst Rating

Based on 4 analysts
Buy
Current Rating
3.250
Target Price
+838.76%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Vyne Therapeutics Inc Highlights

StrengthsRisks
VYNE Therapeutics Inc. is a biopharmaceutical company. The Company is focused on developing differentiated therapies for the treatment of immuno-inflammatory conditions. Its product candidate is VYN201, a locally administered pan-BET inhibitor designed as a soft drug to address diseases involving multiple, diverse inflammatory cell signaling pathways while providing low systemic exposure. Its second program is VYN202, a BD2-selective oral small molecule bromodomain and extra-terminal (BET) inhibitor in preclinical development for the treatment of immuno-inflammatory indications. The Company has rights to research, develop and commercialize products containing BET inhibitor compounds for the treatment of any disease, disorder or condition in humans. Utilizing its InhiBET platform and through its preclinical and clinical activities, the Company is evaluating the impact that BET inhibitor compounds have on regulating pro-inflammatory cytokines.
Growing
The company is in a growing phase, with the latest annual income totaling USD 501.00K.
High Profit Growth
The company's net income leads the industry, with the latest annual income totaling USD 501.00K.
Fairly Valued
The company’s latest PE is -0.36, at a medium 3-year percentile range.
Institutional Selling
The latest institutional holdings are 8.80M shares, decreasing 6.25% quarter-over-quarter.
Held by The Vanguard
Star Investor The Vanguard holds 496.30K shares of this stock.
Higher Market Activity
The company has more investor interest, with a 20-day turnover ratio of 2.76.

Financial Health

Currency: USD Updated: 2025-11-04

The company's current financial score is 6.46, which is lower than the Biotechnology & Medical Research industry's average of 6.92. Its financial status is robust, and its operating efficiency is low. Its latest quarterly revenue reached 69.00K, representing a year-over-year decrease of 65.15%, while its net profit experienced a year-over-year decrease of 38.82%.

Score

Industry at a Glance

Previous score
6.46
Change
0

Financials

9.13

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
No Data

Quality of Earnings

8.61

Operational Efficiency

2.57

Growth Potential

4.90

Shareholder Returns

7.11

Vyne Therapeutics Inc's Company Valuation

Currency: USD Updated: 2025-11-04

The company’s current valuation score is 6.98, which is lower than the Biotechnology & Medical Research industry's average of 7.05. Its current P/E ratio is -0.36, which is -472.85% below the recent high of 1.35 and -1162.69% above the recent low of -4.58.

Score

Industry at a Glance

Previous score
6.98
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 192/407
No Data

Earnings Forecast

Currency: USD Updated: 2025-11-04

The company’s current earnings forecast score is 7.00, which is lower than the Biotechnology & Medical Research industry's average of 8.00. The average price target for Vyne Therapeutics Inc is 3.25, with a high of 4.50 and a low of 2.00.

Score

Industry at a Glance

Previous score
7.00
Change
0

Support & Resistance

No Data

Analyst Rating

Based on 4 analysts
Buy
Current Rating
3.250
Target Price
+838.76%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

521
Total
6
Median
6
Average
Company name
Ratings
Analysts
Vyne Therapeutics Inc
VYNE
4
CRISPR Therapeutics AG
CRSP
30
Ionis Pharmaceuticals Inc
IONS
25
argenx SE
ARGX
25
Intellia Therapeutics Inc
NTLA
25
IQVIA Holdings Inc
IQV
25
1
2
3
...
104

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
No Data

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2025-11-04

The company’s current price momentum score is 5.13, which is lower than the Biotechnology & Medical Research industry's average of 6.41. Sideways: Currently, the stock price is trading between the resistance level at 0.41 and the support level at 0.28, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
4.71
Change
0.42

Support & Resistance

No Data

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(4)
Neutral(1)
Buy(0)
Indicators
Value
Direction
MACD(12,26,9)
-0.006
Sell
RSI(14)
41.053
Neutral
STOCH(KDJ)(9,3,3)
19.565
Sell
ATR(14)
0.028
Low Volatility
CCI(14)
-194.319
Sell
Williams %R
96.734
Oversold
TRIX(12,20)
0.032
Sell
StochRSI(14)
0.000
Oversold
Moving Average
Sell(6)
Neutral(0)
Buy(0)
Indicators
Value
Direction
MA5
0.349
Sell
MA10
0.355
Sell
MA20
0.369
Sell
MA50
0.341
Sell
MA100
0.636
Sell
MA200
1.215
Sell

Institutional Confidence

Currency: USD Updated: 2025-11-04

The company’s current institutional recognition score is 3.00, which is lower than the Biotechnology & Medical Research industry's average of 5.15. The latest institutional shareholding proportion is 34.54%, representing a quarter-over-quarter decrease of 39.15%. The largest institutional shareholder is The Vanguard, holding a total of 496.30K shares, representing 1.95% of shares outstanding, with 39.18% decrease in holdings.

Score

Industry at a Glance

Previous score
3.00
Change
0

Institutional Shareholding

No Data

Shareholder Activity

Name
Shares Held
Chg %
Cormorant Asset Management, LP
1.37M
--
Access Industries, Inc.
1.12M
--
Citadel Advisors LLC
1.04M
-5.48%
Acorn Capital Advisors, LLC
736.57K
-6.28%
Delaware Street Capital, L.L.C.
696.47K
--
Adage Capital Management, L.P.
644.13K
+87.18%
Dafna Capital Management, LLC
636.10K
--
Kennedy Capital Management LLC
570.74K
+631.35%
The Vanguard Group, Inc.
Star Investors
496.30K
+4.34%
Palo Alto Investors LP
445.43K
--
1
2

Risk Assessment

Currency: USD Updated: 2025-11-04

The company’s current risk assessment score is 1.26, which is lower than the Biotechnology & Medical Research industry's average of 3.47. The company's beta value is 2.01. This indicates that the stock tends to outperform the index during upward trending markets but experiences larger declines during downward trending markets.

Score

Industry at a Glance

Previous score
1.26
Change
0
Beta vs S&P 500 index
2.01
VaR
+8.40%
240-Day Maximum Drawdown
+93.29%
240-Day Volatility
+174.23%

Return

Best Daily Return
60 days
+15.23%
120 days
+29.46%
5 years
+73.08%
Worst Daily Return
60 days
-10.39%
120 days
-72.35%
5 years
-72.35%
Sharpe Ratio
60 days
-0.19
120 days
-0.82
5 years
-0.68

Risk Assessment

Maximum Drawdown
240 days
+93.29%
3 years
+96.69%
5 years
+99.87%
Return-to-Drawdown Ratio
240 days
-0.94
3 years
-0.30
5 years
-0.20
Skewness
240 days
-3.01
3 years
+0.91
5 years
+0.80

Volatility

Realised Volatility
240 days
+174.23%
5 years
+126.36%
Standardised True Range
240 days
+45.97%
5 years
+414.46%
Downside Risk-Adjusted Return
120 days
-88.08%
240 days
-88.08%
Maximum Daily Upside Volatility
60 days
+60.38%
Maximum Daily Downside Volatility
60 days
+37.36%

Liquidity

Average Turnover Rate
60 days
+13.43%
120 days
+7.51%
5 years
--
Turnover Deviation
20 days
+275.69%
60 days
+243.72%
120 days
+92.23%

Peer Comparison

Biotechnology & Medical Research
Vyne Therapeutics Inc
Vyne Therapeutics Inc
VYNE
5.51 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Ascendis Pharma A/S
Ascendis Pharma A/S
ASND
8.60 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
CytomX Therapeutics Inc
CytomX Therapeutics Inc
CTMX
8.57 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Insmed Inc
Insmed Inc
INSM
8.47 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Amicus Therapeutics Inc
Amicus Therapeutics Inc
FOLD
8.46 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Krystal Biotech Inc
Krystal Biotech Inc
KRYS
8.36 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
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