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Vyne Therapeutics Inc

VYNE
0.560USD
+0.003+0.48%
Close 02/06, 16:00ETQuotes delayed by 15 min
17.78MMarket Cap
LossP/E TTM

Vyne Therapeutics Inc

0.560
+0.003+0.48%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Vyne Therapeutics Inc

Currency: USD Updated: 2026-02-06

Key Insights

Vyne Therapeutics Inc's fundamentals are relatively very healthy, with an industry-leading ESG disclosure.and its growth potential is significant.Its valuation is considered fairly valued, ranking 196 out of 392 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Buy, with the highest price target at 3.25.In the medium term, the stock price is expected to trend up.Despite an average stock market performance over the past month, the company shows strong fundamentals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Vyne Therapeutics Inc's Score

Industry at a Glance

Industry Ranking
196 / 392
Overall Ranking
379 / 4521
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Media Coverage

Last 24 hours
Coverage Level

Very Low
Very High
Neutral

Vyne Therapeutics Inc Highlights

StrengthsRisks
VYNE Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on developing differentiated therapies to treat chronic inflammatory and immune-mediated conditions with high unmet need. Its lead program is repibresib gel (also known as VYN201), a topically administered, small-molecule pan-BD bromodomain and extra-terminal (BET) inhibitor designed as a soft drug to address diseases involving multiple, diverse inflammatory cell signaling pathways while providing low systemic exposure. Its second program is VYN202, an oral, small-molecule BD2-selective BET inhibitor. The Company has rights to research, develop and commercialize products containing BET inhibitor compounds for the treatment of any disease, disorder or condition in humans. Utilizing its InhiBET platform and through its preclinical and clinical activities, the Company is evaluating the impact that BET inhibitor compounds have on regulating pro-inflammatory cytokines.
Growing
The company is in a growing phase, with the latest annual income totaling USD 501.00K.
High Profit Growth
The company's net income leads the industry, with the latest annual income totaling USD 501.00K.
Fairly Valued
The company’s latest PE is -0.71, at a medium 3-year percentile range.
Institutional Selling
The latest institutional holdings are 4.85M shares, decreasing 58.50% quarter-over-quarter.
Held by The Vanguard
Star Investor The Vanguard holds 314.55K shares of this stock.
Higher Market Activity
The company has more investor interest, with a 20-day turnover ratio of 2.76.

Analyst Rating

Based on 4 analysts
Buy
Current Rating
3.250
Target Price
+462.97%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Financial Health

Currency: USD Updated: 2026-02-06

The current financial score of Vyne Therapeutics Inc is 6.53, ranking 243 out of 392 in the Biotechnology & Medical Research industry. Its financial status is robust, and its operating efficiency is low. Its latest quarterly revenue reached 169.00K, representing a year-over-year increase of 39.67%, while its net profit experienced a year-over-year increase of 40.12%.

Score

Industry at a Glance

Previous score
6.53
Change
0

Financials

9.17

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

7.61

Operational Efficiency

2.83

Growth Potential

5.95

Shareholder Returns

7.07

Vyne Therapeutics Inc's Company Valuation

Currency: USD Updated: 2026-02-06

The current valuation score of Vyne Therapeutics Inc is 6.98, ranking 193 out of 392 in the Biotechnology & Medical Research industry. Its current P/E ratio is -0.71, which is -290.44% below the recent high of 1.35 and -544.96% above the recent low of -4.58.

Score

Industry at a Glance

Previous score
6.98
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 196/392
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2026-02-06

The current earnings forecast score of Vyne Therapeutics Inc is 7.00, ranking 311 out of 392 in the Biotechnology & Medical Research industry. The average price target is 3.25, with a high of 4.50 and a low of 2.00.

Score

Industry at a Glance

Previous score
7.00
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 4 analysts
Buy
Current Rating
3.250
Target Price
+462.97%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

542
Total
6
Median
6
Average
Company name
Ratings
Analysts
Vyne Therapeutics Inc
VYNE
4
CRISPR Therapeutics AG
CRSP
29
argenx SE
ARGX
26
IQVIA Holdings Inc
IQV
26
Intellia Therapeutics Inc
NTLA
24
Beigene Ltd
ONC
24
1
2
3
...
109

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2026-02-06

The current price momentum score of Vyne Therapeutics Inc is 2.86, ranking 372 out of 392 in the Biotechnology & Medical Research industry. Currently, the stock price is trading between the resistance level at 0.58 and the support level at 0.54, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
2.83
Change
0.03

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(5)
Neutral(2)
Buy(0)
Indicators
Value
Direction
MACD(12,26,9)
-0.012
Neutral
RSI(14)
52.443
Neutral
STOCH(KDJ)(9,3,3)
32.515
Sell
ATR(14)
0.020
High Vlolatility
CCI(14)
-124.319
Sell
Williams %R
76.515
Sell
TRIX(12,20)
0.257
Sell
StochRSI(14)
10.726
Sell
Moving Average
Sell(4)
Neutral(0)
Buy(2)
Indicators
Value
Direction
MA5
0.568
Sell
MA10
0.568
Sell
MA20
0.570
Sell
MA50
0.514
Buy
MA100
0.434
Buy
MA200
0.687
Sell

Institutional Confidence

Currency: USD Updated: 2026-02-06

The current institutional shareholding score of Vyne Therapeutics Inc is 3.00, ranking 197 out of 392 in the Biotechnology & Medical Research industry. The latest institutional shareholding proportion is 14.58%, representing a quarter-over-quarter decrease of 43.40%. The largest institutional shareholder is The Vanguard, holding a total of 314.55K shares, representing 0.94% of shares outstanding, with 68.29% decrease in holdings.

Score

Industry at a Glance

Previous score
3.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
Access Industries, Inc.
1.12M
--
Baker Bros. Advisors LP
851.35K
--
Delaware Street Capital, L.L.C.
696.47K
--
Acorn Capital Advisors, LLC
586.57K
-20.36%
Shay Capital LLC
492.58K
--
Acadian Asset Management LLC
446.41K
+1891.32%
The Vanguard Group, Inc.
Star Investors
190.38K
-61.64%
Ikarian Capital LLC
290.00K
--
Two Sigma Investments, LP
277.39K
--
Domzalski (David T)
152.86K
-7.66%
1
2

Risk Assessment

Currency: USD Updated: 2026-02-06

The U.S. Dollar Index is currently in a neutral state, which has a neutral effect on the Biotechnology & Medical Research domestic-focused industry. The Dollar Index (DXY) measures the value of the U.S. dollar against a basket of major currencies, including the euro, yen, pound sterling, Canadian dollar, Swedish krona, and Swiss franc. The current risk assessment score of Vyne Therapeutics Inc is 1.71, ranking 290 out of 392 in the Biotechnology & Medical Research industry. The company's beta value is 2.02. This indicates that the stock tends to outperform the index during upward trending markets but experiences larger declines during downward trending markets. with an industry-leading ESG disclosure.

Score

Industry at a Glance

Previous score
1.71
Change
0
Beta vs S&P 500 index
2.00
VaR
+8.20%
240-Day Maximum Drawdown
+89.75%
240-Day Volatility
+181.69%

Return

Best Daily Return
60 days
+48.99%
120 days
+48.99%
5 years
+73.08%
Worst Daily Return
60 days
-7.28%
120 days
-10.39%
5 years
-72.35%
Sharpe Ratio
60 days
+2.18
120 days
+1.45
5 years
-0.43

Risk Assessment

Maximum Drawdown
240 days
+89.75%
3 years
+96.69%
5 years
+99.69%
Return-to-Drawdown Ratio
240 days
-0.89
3 years
-0.27
5 years
-0.20
Skewness
240 days
-1.71
3 years
-0.43
5 years
+1.04

Volatility

Realised Volatility
240 days
+181.69%
5 years
+128.28%
Standardised True Range
240 days
+16.19%
5 years
+128.42%
Downside Risk-Adjusted Return
120 days
+457.77%
240 days
+457.77%
Maximum Daily Upside Volatility
60 days
+176.18%
Maximum Daily Downside Volatility
60 days
+92.57%

Liquidity

Average Turnover Rate
60 days
+13.43%
120 days
+7.51%
5 years
--
Turnover Deviation
20 days
+275.69%
60 days
+243.72%
120 days
+92.23%

Peer Comparison

Biotechnology & Medical Research
Vyne Therapeutics Inc
Vyne Therapeutics Inc
VYNE
5.12 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Alkermes Plc
Alkermes Plc
ALKS
8.60 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Ascendis Pharma A/S
Ascendis Pharma A/S
ASND
8.53 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Ionis Pharmaceuticals Inc
Ionis Pharmaceuticals Inc
IONS
8.38 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
IQVIA Holdings Inc
IQVIA Holdings Inc
IQV
8.37 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
BioCryst Pharmaceuticals Inc
BioCryst Pharmaceuticals Inc
BCRX
8.17 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
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