Verastem, Inc. is a late-stage development biopharmaceutical company, which focuses on the development and commercialization of new medicines to improve the lives of patients diagnosed with ras sarcoma (RAS)/ mitogen-activated pathway kinase (MAPK) pathway-driven cancers. Its product candidates include avutometinib and defactinib. Avutometinib is an oral RAF/MEK clamp that inhibits MEK1/2 kinase activities and induces inactive complexes of MEK with A-Raf proto-oncogene, potentially serine/threonine kinase (ARAF), B-Raf proto-oncogene serine/threonine kinase (BRAF) and C-raf proto-oncogene serine/threonine kinase, creating antitumor response through maximal RAS/MAPK pathway inhibition. Defactinib is an oral, selective inhibitor of FAK and proline-rich tyrosine kinase (PYK2), the two members of the focal adhesion kinase family of non-receptor protein tyrosine kinases. FAK and PYK2 integrate signals from integrin and growth factor receptors to regulate cell proliferation.
Ticker SymbolVSTM
Company nameVerastem Inc
IPO dateNov 08, 2011
CEOPaterson (Daniel W)
Number of employees78
Security typeOrdinary Share
Fiscal year-endNov 08
Address117 Kendrick Street
CityNEEDHAM
Stock exchangeNASDAQ OMX - NASDAQ BASIC
CountryUnited States of America
Postal code02494
Phone17812924200
Websitehttps://www.verastem.com/
Ticker SymbolVSTM
IPO dateNov 08, 2011
CEOPaterson (Daniel W)
A total of
0.00
USD has been distributed in dividends over the past 5 years.

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