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Vertex Pharmaceuticals Inc

VRTX
419.890USD
+2.680+0.64%
Close 10/30, 16:00ETQuotes delayed by 15 min
107.61BMarket Cap
29.58P/E TTM

Vertex Pharmaceuticals Inc

419.890
+2.680+0.64%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Vertex Pharmaceuticals Inc

Currency: USD Updated: 2025-10-29

Key Insights

The company's fundamentals are relatively very healthy. Its valuation is considered fairly valued,and institutional recognition is very high. Over the past 30 days, multiple analysts have rated the company as a Buy. Despite an average stock market performance, the company shows strong fundamentals and technicals. The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Vertex Pharmaceuticals Inc's Score

Industry at a Glance

Industry Ranking
37 / 160
Overall Ranking
99 / 4623
Industry
Pharmaceuticals

Support & Resistance

No Data

Score Analysis

Current score
Previous score

Analyst Rating

Based on 33 analysts
Buy
Current Rating
482.212
Target Price
+14.16%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Vertex Pharmaceuticals Inc Highlights

StrengthsRisks
Vertex Pharmaceuticals Incorporated is a global biotechnology company. The Company is focused on investing in scientific innovation to create transformative medicines for people with serious diseases, with a focus on specialty markets. It has four approved medicines that treat the underlying cause of cystic fibrosis (CF), and one approved therapy that treats severe sickle cell disease (SCD) and transfusion dependent beta thalassemia (TDT). Its pipeline includes clinical-stage programs in CF, SCD, TDT, acute and neuropathic pain, APOL1-mediated kidney disease, type 1 diabetes, myotonic dystrophy type 1 and alpha-1 antitrypsin deficiency. Its marketed medicines are TRIKAFTA/KAFTRIO, SYMDEKO/SYMKEVI (tezacaftor/ivacaftor and ivacaftor), ORKAMBI (lumacaftor/ivacaftor) and KALYDECO (ivacaftor). It is developing non-autologous (allogeneic) fully differentiated, stem-cell derived islet cell therapies designed to replace insulin-producing islet cells that are destroyed in people with T1D.
High Growth
The company's revenue has grown steadily over the past 3 years, averaging 23.40% year-on-year.
Turnaround to Loss
The company's performance has turned to a loss, with the latest annual loss of USD .
Overvalued
The company’s latest PE is 29.54, at a high 3-year percentile range.
Institutional Selling
The latest institutional holdings are 252.22M shares, decreasing 0.12% quarter-over-quarter.
Held by Jerome Dodson | PARNX
Star Investor Jerome Dodson | PARNX holds 1.65M shares of this stock.
Higher Market Activity
The company has more investor interest, with a 20-day turnover ratio of 0.81.

Financial Health

Currency: USD Updated: 2025-10-29

The company's current financial score is 9.11, which is higher than the Pharmaceuticals industry's average of 7.76. Its financial status is robust, and its operating efficiency is high. Its latest quarterly revenue reached 2.96B, representing a year-over-year increase of 12.06%, while its net profit experienced a year-over-year increase of 128.74%.

Score

Industry at a Glance

Previous score
9.11
Change
0

Financials

9.21

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
No Data

Quality of Earnings

8.51

Operational Efficiency

10.00

Growth Potential

10.00

Shareholder Returns

7.85

Vertex Pharmaceuticals Inc's Company Valuation

Currency: USD Updated: 2025-10-29

The company’s current valuation score is 6.13, which is lower than the Pharmaceuticals industry's average of 7.22. Its current P/E ratio is 29.54, which is 14.94% below the recent high of 33.95 and 1044.06% above the recent low of -278.85.

Score

Industry at a Glance

Previous score
6.13
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 37/160
No Data

Earnings Forecast

Currency: USD Updated: 2025-10-29

The company’s current earnings forecast score is 7.52, which is lower than the Pharmaceuticals industry's average of 7.79. The average price target for Vertex Pharmaceuticals Inc is 481.50, with a high of 603.00 and a low of 330.00.

Score

Industry at a Glance

Previous score
7.52
Change
0

Support & Resistance

No Data

Analyst Rating

Based on 33 analysts
Buy
Current Rating
482.212
Target Price
+15.58%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

169
Total
6
Median
8
Average
Company name
Ratings
Analysts
Vertex Pharmaceuticals Inc
VRTX
33
Biogen Inc
BIIB
36
Amgen Inc
AMGN
34
AbbVie Inc
ABBV
31
Eli Lilly and Co
LLY
31
Gilead Sciences Inc
GILD
30
1
2
3
...
34

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
No Data

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2025-10-29

The company’s current price momentum score is 7.24, which is higher than the Pharmaceuticals industry's average of 6.80. Sideways: Currently, the stock price is trading between the resistance level at 433.07 and the support level at 401.04, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
9.14
Change
-1.9

Support & Resistance

No Data

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(2)
Neutral(3)
Buy(2)
Indicators
Value
Direction
MACD(12,26,9)
-0.258
Neutral
RSI(14)
57.445
Neutral
STOCH(KDJ)(9,3,3)
40.009
Sell
ATR(14)
7.936
High Vlolatility
CCI(14)
20.685
Neutral
Williams %R
42.644
Buy
TRIX(12,20)
0.271
Sell
StochRSI(14)
38.976
Buy
Moving Average
Sell(4)
Neutral(0)
Buy(2)
Indicators
Value
Direction
MA5
420.210
Sell
MA10
421.230
Sell
MA20
415.434
Buy
MA50
401.228
Buy
MA100
421.399
Sell
MA200
445.649
Sell

Institutional Confidence

Currency: USD Updated: 2025-10-29

The company’s current institutional recognition score is 10.00, which is higher than the Pharmaceuticals industry's average of 5.79. The latest institutional shareholding proportion is 98.37%, representing a quarter-over-quarter decrease of 0.19%. The largest institutional shareholder is The Vanguard, holding a total of 23.86M shares, representing 9.31% of shares outstanding, with 3.28% increase in holdings.

Score

Industry at a Glance

Previous score
10.00
Change
0

Institutional Shareholding

No Data

Shareholder Activity

Name
Shares Held
Chg %
Capital World Investors
28.73M
+0.70%
The Vanguard Group, Inc.
Star Investors
23.86M
+2.05%
Capital Research Global Investors
16.11M
+10.81%
BlackRock Institutional Trust Company, N.A.
14.15M
+1.12%
State Street Investment Management (US)
11.78M
-0.11%
Fidelity Management & Research Company LLC
6.30M
-17.28%
Jennison Associates LLC
6.15M
+21.51%
Geode Capital Management, L.L.C.
5.93M
+2.90%
Invesco Capital Management (QQQ Trust)
5.26M
-0.35%
Wellington Management Company, LLP
4.81M
-11.76%
1
2

Risk Assessment

Currency: USD Updated: 2025-10-29

The company’s current risk assessment score is 6.43, which is higher than the Pharmaceuticals industry's average of 5.13. The company's beta value is 0.36. This indicates that the stock tends to underperform the index during upward trending markets but experiences smaller declines during downward trending markets.

Score

Industry at a Glance

Previous score
6.43
Change
0
Beta vs S&P 500 index
0.36
VaR
+2.35%
240-Day Maximum Drawdown
+28.66%
240-Day Volatility
+36.01%

Return

Best Daily Return
60 days
+3.55%
120 days
+3.55%
5 years
+13.23%
Worst Daily Return
60 days
-20.60%
120 days
-20.60%
5 years
-20.60%
Sharpe Ratio
60 days
-0.80
120 days
-0.02
5 years
+0.58

Risk Assessment

Maximum Drawdown
240 days
+28.66%
3 years
+29.07%
5 years
+29.07%
Return-to-Drawdown Ratio
240 days
-0.52
3 years
+0.39
5 years
+0.52
Skewness
240 days
-4.03
3 years
-2.34
5 years
-1.45

Volatility

Realised Volatility
240 days
+36.01%
5 years
+28.21%
Standardised True Range
240 days
+2.81%
5 years
+1.90%
Downside Risk-Adjusted Return
120 days
-2.03%
240 days
-2.03%
Maximum Daily Upside Volatility
60 days
+17.86%
Maximum Daily Downside Volatility
60 days
+11.93%

Liquidity

Average Turnover Rate
60 days
+0.65%
120 days
+0.67%
5 years
--
Turnover Deviation
20 days
+81.48%
60 days
+18.85%
120 days
+21.83%

Peer Comparison

Pharmaceuticals
Vertex Pharmaceuticals Inc
Vertex Pharmaceuticals Inc
VRTX
7.79 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Regeneron Pharmaceuticals Inc
Regeneron Pharmaceuticals Inc
REGN
8.83 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Rhythm Pharmaceuticals Inc
Rhythm Pharmaceuticals Inc
RYTM
8.67 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Collegium Pharmaceutical Inc
Collegium Pharmaceutical Inc
COLL
8.57 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Gilead Sciences Inc
Gilead Sciences Inc
GILD
8.56 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Mckesson Corp
Mckesson Corp
MCK
8.52 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
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