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Vertex Pharmaceuticals Inc

VRTX
469.870USD
-5.810-1.22%
Market hours ETQuotes delayed by 15 min
119.32BMarket Cap
32.84P/E TTM

Vertex Pharmaceuticals Inc

469.870
-5.810-1.22%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Vertex Pharmaceuticals Inc

Currency: USD Updated: 2026-01-29

Key Insights

Vertex Pharmaceuticals Inc's fundamentals are relatively very healthy, and its growth potential is high.Its valuation is considered fairly valued, ranking 6 out of 159 in the Pharmaceuticals industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Buy, with the highest price target at 510.14.In the medium term, the stock price is expected to trend up.Despite an average stock market performance over the past month, the company shows strong fundamentals and technicals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Vertex Pharmaceuticals Inc's Score

Industry at a Glance

Industry Ranking
6 / 159
Overall Ranking
31 / 4540
Industry
Pharmaceuticals

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Media Coverage

Last 24 hours
Coverage Level

Very Low
Very High
Positive

Vertex Pharmaceuticals Inc Highlights

StrengthsRisks
Vertex Pharmaceuticals Incorporated is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases, with a focus on specialty markets. It has seven approved medicines: five that treat the underlying cause of cystic fibrosis (CF), one that treats severe sickle cell disease (SCD) and transfusion dependent beta thalassemia (TDT), and one that treats moderate-to-severe acute pain. Its pipeline includes clinical-stage programs in CF, SCD, beta thalassemia, acute and peripheral neuropathic pain, APOL1-mediated kidney disease, IgA nephropathy and other autoimmune renal diseases and cytopenias, type 1 diabetes, myotonic dystrophy type 1, and autosomal dominant polycystic kidney disease. Its marketed medicines are TRIKAFTA/KAFTRIO (elexacaftor/tezacaftor/ivacaftor and ivacaftor), SYMDEKO/SYMKEVI (elexacaftor/tezacaftor/ivacaftor and ivacaftor), ORKAMBI (lumacaftor/ivacaftor), and KALYDECO (ivacaftor).
High Growth
The company's revenue has grown steadily over the past 3 years, averaging 23.40% year-on-year.
Turnaround to Loss
The company's performance has turned to a loss, with the latest annual loss of USD .
Overvalued
The company’s latest PE is 33.24, at a high 3-year percentile range.
Institutional Selling
The latest institutional holdings are 248.51M shares, decreasing 2.74% quarter-over-quarter.
Held by CI Select Canadian Equity Fund
Star Investor CI Select Canadian Equity Fund holds 5.30K shares of this stock.
Higher Market Activity
The company has more investor interest, with a 20-day turnover ratio of 0.81.

Analyst Rating

Based on 33 analysts
Buy
Current Rating
510.137
Target Price
+7.59%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Financial Health

Currency: USD Updated: 2026-01-29

The current financial score of Vertex Pharmaceuticals Inc is 9.09, ranking 18 out of 159 in the Pharmaceuticals industry. Its financial status is robust, and its operating efficiency is high. Its latest quarterly revenue reached 3.08B, representing a year-over-year increase of 10.99%, while its net profit experienced a year-over-year increase of 3.59%.

Score

Industry at a Glance

Previous score
9.09
Change
0

Financials

9.04

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

8.55

Operational Efficiency

10.00

Growth Potential

10.00

Shareholder Returns

7.86

Vertex Pharmaceuticals Inc's Company Valuation

Currency: USD Updated: 2026-01-29

The current valuation score of Vertex Pharmaceuticals Inc is 6.13, ranking 132 out of 159 in the Pharmaceuticals industry. Its current P/E ratio is 33.24, which is 2.12% below the recent high of 33.95 and 938.76% above the recent low of -278.85.

Score

Industry at a Glance

Previous score
6.13
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 6/159
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2026-01-29

The current earnings forecast score of Vertex Pharmaceuticals Inc is 7.82, ranking 94 out of 159 in the Pharmaceuticals industry. The average price target is 492.50, with a high of 604.00 and a low of 330.00.

Score

Industry at a Glance

Previous score
7.82
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 33 analysts
Buy
Current Rating
510.137
Target Price
+7.59%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

173
Total
6
Median
8
Average
Company name
Ratings
Analysts
Vertex Pharmaceuticals Inc
VRTX
33
Biogen Inc
BIIB
36
Amgen Inc
AMGN
35
Eli Lilly and Co
LLY
33
AbbVie Inc
ABBV
31
Gilead Sciences Inc
GILD
31
1
2
3
...
35

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2026-01-29

The current price momentum score of Vertex Pharmaceuticals Inc is 9.28, ranking 15 out of 159 in the Pharmaceuticals industry. Currently, the stock price is trading between the resistance level at 499.13 and the support level at 440.61, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
9.32
Change
-0.04

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(2)
Neutral(2)
Buy(1)
Indicators
Value
Direction
MACD(12,26,9)
3.657
Buy
RSI(14)
60.455
Neutral
STOCH(KDJ)(9,3,3)
84.262
Overbought
ATR(14)
12.054
High Vlolatility
CCI(14)
99.579
Neutral
Williams %R
16.643
Overbought
TRIX(12,20)
0.128
Sell
StochRSI(14)
51.238
Sell
Moving Average
Sell(1)
Neutral(0)
Buy(5)
Indicators
Value
Direction
MA5
474.602
Sell
MA10
462.386
Buy
MA20
461.450
Buy
MA50
451.347
Buy
MA100
429.695
Buy
MA200
436.819
Buy

Institutional Confidence

Currency: USD Updated: 2026-01-29

The current institutional shareholding score of Vertex Pharmaceuticals Inc is 10.00, ranking 1 out of 159 in the Pharmaceuticals industry. The latest institutional shareholding proportion is 97.94%, representing a quarter-over-quarter decrease of 0.30%. The largest institutional shareholder is The Vanguard, holding a total of 24.10M shares, representing 9.50% of shares outstanding, with 4.33% increase in holdings.

Score

Industry at a Glance

Previous score
10.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
Capital World Investors
25.91M
-9.82%
The Vanguard Group, Inc.
Star Investors
24.10M
+1.01%
Capital Research Global Investors
16.55M
+2.76%
BlackRock Institutional Trust Company, N.A.
14.47M
+2.24%
State Street Investment Management (US)
11.61M
-1.44%
Geode Capital Management, L.L.C.
5.97M
+0.76%
Invesco Capital Management (QQQ Trust)
5.69M
+5.92%
Wellington Management Company, LLP
4.77M
-0.86%
Capital International Investors
4.69M
+77.89%
AllianceBernstein L.P.
4.52M
+3.30%
1
2

Risk Assessment

Currency: USD Updated: 2026-01-29

The U.S. Dollar Index is currently in a neutral state, which has a neutral effect on the Pharmaceuticals domestic-focused industry. The Dollar Index (DXY) measures the value of the U.S. dollar against a basket of major currencies, including the euro, yen, pound sterling, Canadian dollar, Swedish krona, and Swiss franc. The current risk assessment score of Vertex Pharmaceuticals Inc is 9.25, ranking 11 out of 159 in the Pharmaceuticals industry. The company's beta value is 0.31. This indicates that the stock tends to underperform the index during upward trending markets but experiences smaller declines during downward trending markets.

Score

Industry at a Glance

Previous score
9.25
Change
0
Beta vs S&P 500 index
0.31
VaR
+2.35%
240-Day Maximum Drawdown
+28.66%
240-Day Volatility
+32.80%

Return

Best Daily Return
60 days
+6.92%
120 days
+6.92%
5 years
+13.23%
Worst Daily Return
60 days
-3.33%
120 days
-3.33%
5 years
-20.60%
Sharpe Ratio
60 days
+1.96
120 days
+1.85
5 years
+0.72

Risk Assessment

Maximum Drawdown
240 days
+28.66%
3 years
+29.07%
5 years
+29.07%
Return-to-Drawdown Ratio
240 days
+0.10
3 years
+0.67
5 years
+0.80
Skewness
240 days
-4.02
3 years
-2.14
5 years
-1.35

Volatility

Realised Volatility
240 days
+32.80%
5 years
+28.25%
Standardised True Range
240 days
+2.41%
5 years
+1.73%
Downside Risk-Adjusted Return
120 days
+380.38%
240 days
+380.38%
Maximum Daily Upside Volatility
60 days
+22.27%
Maximum Daily Downside Volatility
60 days
+18.68%

Liquidity

Average Turnover Rate
60 days
+0.65%
120 days
+0.67%
5 years
--
Turnover Deviation
20 days
+81.48%
60 days
+18.85%
120 days
+21.83%

Peer Comparison

Pharmaceuticals
Vertex Pharmaceuticals Inc
Vertex Pharmaceuticals Inc
VRTX
8.54 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Gilead Sciences Inc
Gilead Sciences Inc
GILD
8.89 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Mirum Pharmaceuticals Inc
Mirum Pharmaceuticals Inc
MIRM
8.79 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Catalyst Pharmaceuticals Inc
Catalyst Pharmaceuticals Inc
CPRX
8.77 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
ANI Pharmaceuticals Inc
ANI Pharmaceuticals Inc
ANIP
8.65 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Mckesson Corp
Mckesson Corp
MCK
8.65 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
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