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Taysha Gene Therapies Inc

TSHA
4.075USD
-0.245-5.67%
Close 03/30, 16:00ETQuotes delayed by 15 min
140.67MMarket Cap
LossP/E TTM

Taysha Gene Therapies Inc

4.075
-0.245-5.67%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Taysha Gene Therapies Inc

Currency: USD Updated: 2026-03-27

Key Insights

Taysha Gene Therapies Inc's fundamentals are relatively very healthy, with an industry-leading ESG disclosure.and its growth potential is high.Its valuation is considered fairly valued, ranking 55 out of 391 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Buy, with the highest price target at 11.36.In the medium term, the stock price is expected to trend down.Despite a weak stock market performance over the past month, the company shows strong fundamentals and technicals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Taysha Gene Therapies Inc's Score

Industry at a Glance

Industry Ranking
55 / 391
Overall Ranking
162 / 4542
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Media Coverage

Last 24 hours
Coverage Level

Very Low
Very High
Positive

Taysha Gene Therapies Inc Highlights

StrengthsRisks
Taysha Gene Therapies Inc is a clinical-stage biotechnology company, which is focused on advancing adeno-associated virus (AAV)-based gene therapies for severe monogenic diseases of the central nervous system. The Company’s lead clinical program, TSHA-102, is in development for the treatment of Rett syndrome, a rare neurodevelopmental disorder. The Company is evaluating TSHA-102 in the REVEALPhase I/II adolescent and adult clinical trial, which is a first-in-human, open-label, randomized, dose escalation and dose-expansion, multicenter study evaluating the safety and preliminary efficacy of TSHA-102 in female patients aged 12-years and older with Rett syndrome. It has acquired a worldwide right to a clinical-stage, intrathecally dosed AAV9 gene therapy program, TSHA-120, for the treatment of giant axonal neuropathy (GAN). TSHA-105 is a gene replacement therapy in development for the treatment of SLC13A5 deficiency, a rare autosomal recessive epileptic encephalopathy.
Growing
The company is in a growing phase, with the latest annual income totaling USD 9.77M.
Undervalued
The company’s latest PE is -11.94, at a low 3-year percentile range.
Institutional Selling
The latest institutional holdings are 268.88M shares, decreasing 5.45% quarter-over-quarter.
Held by PRFDX
Star Investor PRFDX holds 20.94K shares of this stock.

Analyst Rating

Based on 14 analysts
Buy
Current Rating
11.357
Target Price
+162.90%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Financial Health

Currency: USD Updated: 2026-03-27

The current financial score of Taysha Gene Therapies Inc is 6.45, ranking 245 out of 391 in the Biotechnology & Medical Research industry. Its financial status is robust, and its operating efficiency is low. Its latest quarterly revenue reached 5.49M, representing a year-over-year increase of 171.27%, while its net profit experienced a year-over-year increase of 48.26%.

Score

Industry at a Glance

Previous score
6.46
Change
-0.01

Financials

9.02

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

7.31

Operational Efficiency

2.57

Growth Potential

6.25

Shareholder Returns

7.11

Taysha Gene Therapies Inc's Company Valuation

Currency: USD Updated: 2026-03-27

The current valuation score of Taysha Gene Therapies Inc is 6.50, ranking 261 out of 391 in the Biotechnology & Medical Research industry. Its current P/E ratio is -11.94, which is -142.90% below the recent high of 5.12 and -49.01% above the recent low of -17.79.

Score

Industry at a Glance

Previous score
6.50
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 55/391
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2026-03-27

The current earnings forecast score of Taysha Gene Therapies Inc is 8.57, ranking 100 out of 391 in the Biotechnology & Medical Research industry. The average price target is 10.50, with a high of 19.00 and a low of 5.00.

Score

Industry at a Glance

Previous score
8.57
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 14 analysts
Buy
Current Rating
11.357
Target Price
+179.05%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

548
Total
6
Median
6
Average
Company name
Ratings
Analysts
Taysha Gene Therapies Inc
TSHA
14
CRISPR Therapeutics AG
CRSP
29
argenx SE
ARGX
26
IQVIA Holdings Inc
IQV
26
Intellia Therapeutics Inc
NTLA
24
Beigene Ltd
ONC
24
1
2
3
...
110

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2026-03-27

The current price momentum score of Taysha Gene Therapies Inc is 6.74, ranking 148 out of 391 in the Biotechnology & Medical Research industry. Currently, the stock price is trading between the resistance level at 4.55 and the support level at 3.81, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
7.32
Change
-0.58

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(5)
Neutral(1)
Buy(0)
Indicators
Value
Direction
MACD(12,26,9)
-0.077
Sell
RSI(14)
39.500
Neutral
STOCH(KDJ)(9,3,3)
16.637
Sell
ATR(14)
0.262
High Vlolatility
CCI(14)
-193.455
Sell
Williams %R
94.161
Oversold
TRIX(12,20)
-0.283
Sell
StochRSI(14)
21.236
Sell
Moving Average
Sell(5)
Neutral(0)
Buy(1)
Indicators
Value
Direction
MA5
4.234
Sell
MA10
4.369
Sell
MA20
4.461
Sell
MA50
4.573
Sell
MA100
4.740
Sell
MA200
4.004
Buy

Institutional Confidence

Currency: USD Updated: 2026-03-27

The current institutional shareholding score of Taysha Gene Therapies Inc is 10.00, ranking 1 out of 391 in the Biotechnology & Medical Research industry. The latest institutional shareholding proportion is 98.16%, representing a quarter-over-quarter increase of 3.20%. The largest institutional shareholder is The Vanguard, holding a total of 13.23M shares, representing 4.61% of shares outstanding, with 32.30% increase in holdings.

Score

Industry at a Glance

Previous score
10.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
Manning (Paul B.)
25.60M
+3.02%
RA Capital Management, LP
23.56M
--
Avoro Capital Advisors LLC
21.70M
--
Morgan Stanley & Co. LLC
19.08M
+30.12%
BlackRock Institutional Trust Company, N.A.
15.03M
+24.29%
RTW Investments L.P.
24.35M
-2.67%
Vestal Point Capital, LP
5.50M
+83.33%
Fidelity Management & Research Company LLC
14.59M
-6.62%
Goldman Sachs & Company, Inc.
13.20M
+5.40%
The Vanguard Group, Inc.
Star Investors
12.85M
+17.95%
1
2

Risk Assessment

Currency: USD Updated: 2026-03-27

The U.S. Dollar Index is currently in a neutral state, which has a neutral effect on the Biotechnology & Medical Research domestic-focused industry. The Dollar Index (DXY) measures the value of the U.S. dollar against a basket of major currencies, including the euro, yen, pound sterling, Canadian dollar, Swedish krona, and Swiss franc. The current risk assessment score of Taysha Gene Therapies Inc is 4.23, ranking 95 out of 391 in the Biotechnology & Medical Research industry. The company's beta value is 1.10. This indicates that the stock tends to outperform the index during upward trending markets but experiences larger declines during downward trending markets. with an industry-leading ESG disclosure.

Score

Industry at a Glance

Previous score
4.23
Change
0
Beta vs S&P 500 index
1.10
VaR
+8.40%
240-Day Maximum Drawdown
+31.13%
240-Day Volatility
+87.80%

Return

Best Daily Return
60 days
+10.90%
120 days
+12.69%
5 years
+188.23%
Worst Daily Return
60 days
-9.03%
120 days
-10.08%
5 years
-27.98%
Sharpe Ratio
60 days
-1.97
120 days
-0.19
5 years
+0.23

Risk Assessment

Maximum Drawdown
240 days
+31.13%
3 years
+72.90%
5 years
+97.76%
Return-to-Drawdown Ratio
240 days
+7.29
3 years
+2.31
5 years
-0.17
Skewness
240 days
+3.28
3 years
+11.16
5 years
+9.93

Volatility

Realised Volatility
240 days
+87.80%
5 years
+111.88%
Standardised True Range
240 days
+6.54%
5 years
+8.81%
Downside Risk-Adjusted Return
120 days
-34.60%
240 days
-34.60%
Maximum Daily Upside Volatility
60 days
+38.98%
Maximum Daily Downside Volatility
60 days
+39.76%

Liquidity

Average Turnover Rate
60 days
+1.45%
120 days
+1.56%
5 years
--
Turnover Deviation
20 days
-4.18%
60 days
+4.18%
120 days
+11.64%

Peer Comparison

Biotechnology & Medical Research
Taysha Gene Therapies Inc
Taysha Gene Therapies Inc
TSHA
7.07 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Alkermes Plc
Alkermes Plc
ALKS
8.42 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Madrigal Pharmaceuticals Inc
Madrigal Pharmaceuticals Inc
MDGL
8.27 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
BioCryst Pharmaceuticals Inc
BioCryst Pharmaceuticals Inc
BCRX
8.27 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Day One Biopharmaceuticals Inc
Day One Biopharmaceuticals Inc
DAWN
8.26 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
IQVIA Holdings Inc
IQVIA Holdings Inc
IQV
8.21 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
View more
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