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Stoke Therapeutics Inc

STOK
32.850USD
-0.850-2.52%
Close 03/27, 16:00ETQuotes delayed by 15 min
994.36MMarket Cap
LossP/E TTM

Stoke Therapeutics Inc

32.850
-0.850-2.52%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Stoke Therapeutics Inc

Currency: USD Updated: 2026-03-27

Key Insights

Stoke Therapeutics Inc's fundamentals are relatively healthy, with an industry-leading ESG disclosure.and its growth potential is good.Its valuation is considered fairly valued, ranking 45 out of 391 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Strong Buy, with the highest price target at 43.10.In the medium term, the stock price is expected to remain stable.Despite a weak stock market performance over the past month, the company shows strong fundamentals and technicals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Stoke Therapeutics Inc's Score

Industry at a Glance

Industry Ranking
45 / 391
Overall Ranking
145 / 4542
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Media Coverage

Last 24 hours
Coverage Level

Very Low
Very High
Neutral

Stoke Therapeutics Inc Highlights

StrengthsRisks
Stoke Therapeutics, Inc. is a biotechnology company dedicated to addressing the underlying cause of severe diseases by upregulating protein expression with ribonucleic acid (RNA)-based medicines. The Company, through its proprietary Targeted Augmentation of Nuclear Gene Output (TANGO) approach, is engaged in developing antisense oligonucleotides (ASOs) to selectively restore protein levels. Its first compound, zorevunersen (STK-002), is in clinical testing for the treatment of Dravet syndrome, a severe and progressive genetic epilepsy. TANGO aims to restore missing proteins by increasing or stoking protein output from healthy genes, thus compensating for the non-functioning copy of the gene. The Company is pursuing the development of STK-002 for the treatment of autosomal dominant optic atrophy (ADOA), the most common inherited optic nerve disorder. The Company’s initial focus is haploinsufficiency and diseases of the central nervous system and the eye.
High Growth
The company's revenue has grown steadily over the past 3 years, averaging 2000.46% year-on-year.
Undervalued
The company’s latest PE is -282.56, at a low 3-year percentile range.
Institutional Selling
The latest institutional holdings are 69.93M shares, decreasing 5.77% quarter-over-quarter.
Held by Invesco
Star Investor Invesco holds 235.70K shares of this stock.

Analyst Rating

Based on 12 analysts
Strong Buy
Current Rating
43.100
Target Price
+33.93%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Financial Health

Currency: USD Updated: 2026-03-27

The current financial score of Stoke Therapeutics Inc is 7.07, ranking 134 out of 391 in the Biotechnology & Medical Research industry. Its financial status is stable, and its operating efficiency is high. Its latest quarterly revenue reached 1.40M, representing a year-over-year decrease of 93.80%, while its net profit experienced a year-over-year decrease of 452.70%.

Score

Industry at a Glance

Previous score
7.07
Change
0

Financials

7.95

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

7.46

Operational Efficiency

8.96

Growth Potential

3.81

Shareholder Returns

7.16

Stoke Therapeutics Inc's Company Valuation

Currency: USD Updated: 2026-03-27

The current valuation score of Stoke Therapeutics Inc is 5.39, ranking 376 out of 391 in the Biotechnology & Medical Research industry. Its current P/E ratio is -282.56, which is -119.12% below the recent high of 54.03 and -3.38% above the recent low of -292.10.

Score

Industry at a Glance

Previous score
5.39
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 45/391
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2026-03-27

The current earnings forecast score of Stoke Therapeutics Inc is 9.00, ranking 19 out of 391 in the Biotechnology & Medical Research industry. The average price target is 33.50, with a high of 39.00 and a low of 24.00.

Score

Industry at a Glance

Previous score
9.00
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 12 analysts
Strong Buy
Current Rating
43.100
Target Price
+27.89%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

548
Total
6
Median
6
Average
Company name
Ratings
Analysts
Stoke Therapeutics Inc
STOK
12
CRISPR Therapeutics AG
CRSP
29
IQVIA Holdings Inc
IQV
27
argenx SE
ARGX
26
Beigene Ltd
ONC
24
Intellia Therapeutics Inc
NTLA
24
1
2
3
...
110

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2026-03-27

The current price momentum score of Stoke Therapeutics Inc is 7.19, ranking 71 out of 391 in the Biotechnology & Medical Research industry. Currently, the stock price is trading between the resistance level at 38.76 and the support level at 28.40, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
7.35
Change
-0.16

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(3)
Neutral(4)
Buy(0)
Indicators
Value
Direction
MACD(12,26,9)
-0.571
Neutral
RSI(14)
46.555
Neutral
STOCH(KDJ)(9,3,3)
55.701
Neutral
ATR(14)
2.522
High Vlolatility
CCI(14)
-41.902
Neutral
Williams %R
71.147
Sell
TRIX(12,20)
-0.111
Sell
StochRSI(14)
44.051
Sell
Moving Average
Sell(4)
Neutral(0)
Buy(2)
Indicators
Value
Direction
MA5
33.184
Sell
MA10
33.047
Sell
MA20
34.488
Sell
MA50
32.897
Sell
MA100
31.493
Buy
MA200
25.539
Buy

Institutional Confidence

Currency: USD Updated: 2026-03-27

The current institutional shareholding score of Stoke Therapeutics Inc is 10.00, ranking 1 out of 391 in the Biotechnology & Medical Research industry. The latest institutional shareholding proportion is 122.44%, representing a quarter-over-quarter increase of 6.05%. The largest institutional shareholder is The Vanguard, holding a total of 3.14M shares, representing 5.31% of shares outstanding, with 4.33% increase in holdings.

Score

Industry at a Glance

Previous score
10.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
RTW Investments L.P.
5.12M
--
Lynx1 Capital Advisors LLC
5.40M
--
Fidelity Management & Research Company LLC
5.93M
-0.40%
Redmile Group, LLC
4.18M
-4.58%
Morgan Stanley & Co. LLC
3.48M
+3.02%
BlackRock Institutional Trust Company, N.A.
3.30M
+10.83%
Baker Bros. Advisors LP
4.63M
--
TD Securities, Inc.
3.17M
--
The Vanguard Group, Inc.
Star Investors
3.15M
+7.30%
State Street Investment Management (US)
1.43M
-4.12%
1
2

Risk Assessment

Currency: USD Updated: 2026-03-27

The U.S. Dollar Index is currently in a neutral state, which has a neutral effect on the Biotechnology & Medical Research domestic-focused industry. The Dollar Index (DXY) measures the value of the U.S. dollar against a basket of major currencies, including the euro, yen, pound sterling, Canadian dollar, Swedish krona, and Swiss franc. The current risk assessment score of Stoke Therapeutics Inc is 4.22, ranking 96 out of 391 in the Biotechnology & Medical Research industry. The company's beta value is 1.21. This indicates that the stock tends to outperform the index during upward trending markets but experiences larger declines during downward trending markets. with an industry-leading ESG disclosure.

Score

Industry at a Glance

Previous score
4.22
Change
0
Beta vs S&P 500 index
1.21
VaR
+7.20%
240-Day Maximum Drawdown
+37.16%
240-Day Volatility
+81.40%

Return

Best Daily Return
60 days
+10.94%
120 days
+15.16%
5 years
+58.31%
Worst Daily Return
60 days
-10.44%
120 days
-13.12%
5 years
-32.11%
Sharpe Ratio
60 days
+0.46
120 days
+1.16
5 years
+0.37

Risk Assessment

Maximum Drawdown
240 days
+37.16%
3 years
+75.62%
5 years
+91.30%
Return-to-Drawdown Ratio
240 days
+9.90
3 years
+0.83
5 years
-0.02
Skewness
240 days
+0.89
3 years
+2.10
5 years
+1.53

Volatility

Realised Volatility
240 days
+81.40%
5 years
+85.72%
Standardised True Range
240 days
+4.79%
5 years
+3.26%
Downside Risk-Adjusted Return
120 days
+191.30%
240 days
+191.30%
Maximum Daily Upside Volatility
60 days
+58.93%
Maximum Daily Downside Volatility
60 days
+58.35%

Liquidity

Average Turnover Rate
60 days
+1.37%
120 days
+1.46%
5 years
--
Turnover Deviation
20 days
+17.93%
60 days
-1.84%
120 days
+4.52%

Peer Comparison

Biotechnology & Medical Research
Stoke Therapeutics Inc
Stoke Therapeutics Inc
STOK
7.24 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Alkermes Plc
Alkermes Plc
ALKS
8.42 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Madrigal Pharmaceuticals Inc
Madrigal Pharmaceuticals Inc
MDGL
8.27 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
BioCryst Pharmaceuticals Inc
BioCryst Pharmaceuticals Inc
BCRX
8.27 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Day One Biopharmaceuticals Inc
Day One Biopharmaceuticals Inc
DAWN
8.26 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
IQVIA Holdings Inc
IQVIA Holdings Inc
IQV
8.21 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
View more
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