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Stoke Therapeutics Inc

STOK

23.368USD

+0.628+2.76%
Market hours ETQuotes delayed by 15 min
1.28BMarket Cap
24.37P/E TTM

Stoke Therapeutics Inc

23.368

+0.628+2.76%

TradingKey Stock Score

Overall Financial Health

Valuation Dimensions

Earnings Forecast

Price Momentum

Institutional Confidence

Risk Assessment

Peer Comparison

TradingKey Stock Score

Overall Financial Health

Valuation Dimensions

Earnings Forecast

Price Momentum

Institutional Confidence

Risk Assessment

Peer Comparison

TradingKey Stock Score

Currency: USD Updated2025-09-17

Key Insights

The company's fundamentals are relatively very healthy. Its valuation is considered fairly valued,and institutional recognition is very high. Over the past 30 days, multiple analysts have rated the company as a Buy. Despite a very weak market performance, the company shows strong fundamentals and technicals. The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Industry Ranking
5 / 507
Overall Ranking
61 / 4723
Industry
Biotechnology & Medical Research

Support & Resistance

No Data

Score Analysis

Current score
Previous score

Analyst Rating

Based on 11 analysts
Buy
Current Rating
24.222
Target Price
+4.59%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Company Highlights

StrengthsRisks
Stoke Therapeutics, Inc. is a biotechnology company dedicated to addressing the underlying cause of severe diseases by upregulating protein expression with ribonucleic acid (RNA)-based medicines. The Company, through its proprietary Targeted Augmentation of Nuclear Gene Output (TANGO) approach, is engaged in developing antisense oligonucleotides (ASOs) to selectively restore protein levels. Its first compound, STK-001, is in clinical testing for the treatment of Dravet syndrome, a severe and progressive genetic epilepsy. TANGO aims to restore missing proteins by increasing or stoking protein output from healthy genes, thus compensating for the non-functioning copy of the gene. The Company is pursuing the development of STK-002 for the treatment of autosomal dominant optic atrophy (ADOA), the most common inherited optic nerve disorder. The Company’s initial focus is haploinsufficiency and diseases of the central nervous system and the eye.
High Growth
The company's revenue has grown steadily over the past 3 years, averaging 194.68% year-on-year.
Growing
The company is in a growing phase, with the latest annual income totaling USD 36.55M.
Overvalued
The company’s latest PE is 25.10, at a high 3-year percentile range.
Institutional Selling
The latest institutional holdings are 63.05M shares, decreasing 8.13% quarter-over-quarter.
Held by The Vanguard
Star Investor The Vanguard holds 2.94M shares of this stock.

Financial Health

Currency: USD Updated2025-09-17

The company's current financial score is 8.33, which is higher than the Biotechnology & Medical Research industry's average of 6.93. Its financial status is robust, and its operating efficiency is high. Its latest quarterly revenue reached 13.82M, representing a year-over-year increase of 186.01%, while its net profit experienced a year-over-year increase of 8.61%.

Score

Industry at a Glance

Previous score
8.33
Change
0

Financials

9.89

Key Metrics

Cash and cash equivalents

Total assets

Total liabilities

Free cash flow

No Data

Quality of Earnings

7.84

Operational Efficiency

10.00

Growth Potential

6.69

Shareholder Returns

7.21

Company Valuation

Currency: USD Updated2025-09-17

The company’s current valuation score is 3.99, which is higher than the Biotechnology & Medical Research industry's average of 3.06. Its current P/E ratio is 25.10, which is -108.66% below the recent high of -2.17 and 120.60% above the recent low of -5.17.

Score

Industry at a Glance

Previous score
3.13
Change
0.86

Valuation Dimensions

P/E

P/B

P/S

P/CF

Industry Ranking 5/507
No Data

Earnings Forecast

Currency: USD Updated2025-09-17

The company’s current earnings forecast score is 8.55, which is higher than the Biotechnology & Medical Research industry's average of 8.03. The average price target for Stoke Therapeutics Inc is 24.00, with a high of 35.00 and a low of 15.00.

Score

Industry at a Glance

Previous score
8.55
Change
0

Support & Resistance

No Data

Analyst Rating

Based on 11 analysts
Buy
Current Rating
24.222
Target Price
+4.59%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

554
Total
5
Median
6
Average
Company name
Ratings
Analysts
Stoke Therapeutics Inc
STOK
11
CRISPR Therapeutics AG
CRSP
30
Ionis Pharmaceuticals Inc
IONS
26
Intellia Therapeutics Inc
NTLA
26
Exact Sciences Corp
EXAS
26
IQVIA Holdings Inc
IQV
25
1
2
3
...
111

Financial Forecasting

EPS

Revenue

Net Profit

EBIT

No Data

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated2025-09-17

The company’s current price momentum score is 9.18, which is higher than the Biotechnology & Medical Research industry's average of 6.32. Sideways: Currently, the stock price is trading between the resistance level at 25.56 and the support level at 18.96, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
9.28
Change
-0.1

Support & Resistance

No Data

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(2)
Neutral(1)
Buy(3)
Indicators
Value
Direction
MACD(12,26,9)
0.046
Buy
RSI(14)
73.551
Buy
STOCH(KDJ)(9,3,3)
71.262
Sell
ATR(14)
1.232
High Vlolatility
CCI(14)
69.691
Neutral
Williams %R
32.069
Buy
TRIX(12,20)
1.663
Sell
StochRSI(14)
0.000
Oversold
Moving Average
Sell(0)
Neutral(0)
Buy(6)
Indicators
Value
Direction
MA5
23.328
Buy
MA10
22.367
Buy
MA20
20.933
Buy
MA50
16.563
Buy
MA100
13.505
Buy
MA200
11.553
Buy

Institutional Confidence

Currency: USD Updated2025-09-17

The company’s current institutional recognition score is 10.00, which is higher than the Biotechnology & Medical Research industry's average of 5.96. The latest institutional shareholding proportion is 115.48%, representing a quarter-over-quarter decrease of 5.85%. The largest institutional shareholder is The Vanguard, holding a total of 2.94M shares, representing 5.36% of shares outstanding, with 6.39% increase in holdings.

Score

Industry at a Glance

Previous score
10.00
Change
0

Institutional Shareholding

No Data

Shareholder Activity

Name
Shares Held
Chg %
Fidelity Management & Research Company LLC
2.47M
+1394.59%
Lynx1 Capital Advisors LLC
5.29M
+2.02%
RTW Investments L.P.
5.12M
--
Baker Bros. Advisors LP
4.63M
--
Redmile Group, LLC
4.49M
-2.34%
Morgan Stanley & Co. LLC
3.22M
+8.62%
TD Securities, Inc.
3.17M
--
BlackRock Institutional Trust Company, N.A.
2.83M
+0.04%
The Vanguard Group, Inc.
Star Investors
2.78M
+1.95%
Marshall Wace LLP
2.13M
+124.06%
1
2

Risk Assessment

Currency: USD Updated2025-09-17

The company’s current risk assessment score is 3.18, which is lower than the Biotechnology & Medical Research industry's average of 3.33. The company's beta value is 1.23. This indicates that the stock tends to outperform the index during upward trending markets but experiences larger declines during downward trending markets.

Score

Industry at a Glance

Previous score
3.18
Change
0
Beta vs S&P 500 index
1.23
VaR
+7.18%
240-Day Maximum Drawdown
+57.61%
240-Day Volatility
+77.87%
Return
Best Daily Return
60 days
+24.98%
120 days
+24.98%
5 years
+58.31%
Worst Daily Return
60 days
-6.88%
120 days
-9.79%
5 years
-32.11%
Sharpe Ratio
60 days
+4.42
120 days
+3.63
5 years
+0.20
Risk Assessment
Maximum Drawdown
240 days
+57.61%
3 years
+75.62%
5 years
+95.17%
Return-to-Drawdown Ratio
240 days
+1.46
3 years
+0.30
5 years
-0.11
Skewness
240 days
+0.52
3 years
+1.88
5 years
+1.58
Volatility
Realised Volatility
240 days
+77.87%
5 years
+84.28%
Standardised True Range
240 days
+3.28%
5 years
+5.19%
Downside Risk-Adjusted Return
120 days
+675.97%
240 days
+675.97%
Maximum Daily Upside Volatility
60 days
+79.41%
Maximum Daily Downside Volatility
60 days
+39.36%
Liquidity
Average Turnover Rate
60 days
+1.37%
120 days
+1.46%
5 years
--
Turnover Deviation
20 days
+17.93%
60 days
-1.84%
120 days
+4.52%

Peer Comparison

Biotechnology & Medical Research
Stoke Therapeutics Inc
Stoke Therapeutics Inc
STOK
7.55 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Krystal Biotech Inc
Krystal Biotech Inc
KRYS
8.13 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Alkermes Plc
Alkermes Plc
ALKS
7.85 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
ACADIA Pharmaceuticals Inc
ACADIA Pharmaceuticals Inc
ACAD
7.65 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Zymeworks Inc
Zymeworks Inc
ZYME
7.61 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Insmed Inc
Insmed Inc
INSM
7.55 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
View more
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