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Stoke Therapeutics Inc

STOK
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30.080USD
-1.280-4.08%
Close 05/15, 16:00ETQuotes delayed by 15 min
1.87BMarket Cap
LossP/E TTM

Stoke Therapeutics Inc

30.080
-1.280-4.08%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Stoke Therapeutics Inc

Currency: USD Updated: 2026-05-15

Key Insights

Stoke Therapeutics Inc's fundamentals are relatively healthy, with an industry-leading ESG disclosure.and its growth potential is good.Its valuation is considered fairly valued, ranking 50 out of 382 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Strong Buy, with the highest price target at 45.10.In the medium term, the stock price is expected to trend down.Despite a very weak market performance over the past month, the company shows strong fundamentals and technicals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Stoke Therapeutics Inc's Score

Industry at a Glance

Industry Ranking
50 / 382
Overall Ranking
156 / 4482
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Media Coverage

Last 24 hours
Coverage Level

Very Low
Very High
Neutral

Stoke Therapeutics Inc Highlights

StrengthsRisks
Stoke Therapeutics, Inc. is a biotechnology company dedicated to addressing the underlying cause of severe diseases by upregulating protein expression with ribonucleic acid (RNA)-based medicines. The Company, through its proprietary Targeted Augmentation of Nuclear Gene Output (TANGO) approach, is engaged in developing antisense oligonucleotides (ASOs) to selectively restore protein levels. Its first compound, zorevunersen (STK-002), is in clinical testing for the treatment of Dravet syndrome, a severe and progressive genetic epilepsy. TANGO aims to restore missing proteins by increasing or stoking protein output from healthy genes, thus compensating for the non-functioning copy of the gene. The Company is pursuing the development of STK-002 for the treatment of autosomal dominant optic atrophy (ADOA), the most common inherited optic nerve disorder. The Company’s initial focus is haploinsufficiency and diseases of the central nervous system and the eye.
High Growth
The company's revenue has grown steadily over the past 3 years, averaging 2000.46% year-on-year.
Undervalued
The company’s latest PE is -10.52, at a low 3-year percentile range.
Institutional Selling
The latest institutional holdings are 73.67M shares, decreasing 7.37% quarter-over-quarter.
Held by CI Select Canadian Equity Fund
Star Investor CI Select Canadian Equity Fund holds 110.00 shares of this stock.
Lower Market Activity
The company has less investor interest, with a 20-day turnover ratio of -0.38.

Analyst Rating

Based on 12 analysts
Strong Buy
Current Rating
45.100
Target Price
+42.27%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Financial Health

Currency: USD Updated: 2026-05-15

The current financial score of Stoke Therapeutics Inc is 7.07, ranking 128 out of 382 in the Biotechnology & Medical Research industry. Its financial status is stable, and its operating efficiency is high. Its latest quarterly revenue reached 6.23M, representing a year-over-year decrease of 96.07%, while its net profit experienced a year-over-year decrease of 144.30%.

Score

Industry at a Glance

Previous score
7.07
Change
0

Financials

7.95

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

7.46

Operational Efficiency

8.96

Growth Potential

3.81

Shareholder Returns

7.16

Stoke Therapeutics Inc's Company Valuation

Currency: USD Updated: 2026-05-15

The current valuation score of Stoke Therapeutics Inc is 5.39, ranking 367 out of 382 in the Biotechnology & Medical Research industry. Its current P/E ratio is -10.52, which is -613.73% below the recent high of 54.03 and -2947.98% above the recent low of -320.57.

Score

Industry at a Glance

Previous score
5.39
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 50/382
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2026-05-15

The current earnings forecast score of Stoke Therapeutics Inc is 9.00, ranking 17 out of 382 in the Biotechnology & Medical Research industry. The average price target is 33.50, with a high of 39.00 and a low of 24.00.

Score

Industry at a Glance

Previous score
9.00
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 12 analysts
Strong Buy
Current Rating
45.100
Target Price
+43.81%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

554
Total
5
Median
6
Average
Company name
Ratings
Analysts
Stoke Therapeutics Inc
STOK
12
CRISPR Therapeutics AG
CRSP
27
argenx SE
ARGX
26
IQVIA Holdings Inc
IQV
26
Beigene Ltd
ONC
26
Ionis Pharmaceuticals Inc
IONS
25
1
2
3
...
111

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2026-05-15

The current price momentum score of Stoke Therapeutics Inc is 6.76, ranking 159 out of 382 in the Biotechnology & Medical Research industry. Currently, the stock price is trading between the resistance level at 35.01 and the support level at 27.43, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
6.97
Change
-0.21

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(3)
Neutral(1)
Buy(0)
Indicators
Value
Direction
MACD(12,26,9)
-0.657
Sell
RSI(14)
32.040
Neutral
STOCH(KDJ)(9,3,3)
16.194
Sell
ATR(14)
1.613
High Vlolatility
CCI(14)
-211.286
Oversold
Williams %R
93.141
Oversold
TRIX(12,20)
-0.300
Sell
StochRSI(14)
0.000
Oversold
Moving Average
Sell(5)
Neutral(0)
Buy(1)
Indicators
Value
Direction
MA5
31.654
Sell
MA10
32.437
Sell
MA20
33.328
Sell
MA50
33.916
Sell
MA100
33.070
Sell
MA200
29.209
Buy

Institutional Confidence

Currency: USD Updated: 2026-05-15

The current institutional shareholding score of Stoke Therapeutics Inc is 10.00, ranking 1 out of 382 in the Biotechnology & Medical Research industry. The latest institutional shareholding proportion is 118.29%, representing a quarter-over-quarter decrease of 3.39%. The largest institutional shareholder is Steven Cohen, holding a total of 1.22M shares, representing 1.96% of shares outstanding, with 1.00% increase in holdings.

Score

Industry at a Glance

Previous score
10.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
RTW Investments L.P.
5.55M
+8.26%
Lynx1 Capital Advisors LLC
5.40M
--
Fidelity Management & Research Company LLC
4.75M
-19.92%
Redmile Group, LLC
4.03M
-3.39%
Morgan Stanley & Co. LLC
3.49M
+0.50%
BlackRock Institutional Trust Company, N.A.
3.44M
+4.09%
Baker Bros. Advisors LP
3.34M
-27.99%
TD Securities, Inc.
3.17M
--
State Street Investment Management (US)
2.50M
+75.19%
1
2

Risk Assessment

Currency: USD Updated: 2026-05-15

The U.S. Dollar Index is currently in a neutral state, which has a neutral effect on the Biotechnology & Medical Research domestic-focused industry. The Dollar Index (DXY) measures the value of the U.S. dollar against a basket of major currencies, including the euro, yen, pound sterling, Canadian dollar, Swedish krona, and Swiss franc. The current risk assessment score of Stoke Therapeutics Inc is 4.22, ranking 93 out of 382 in the Biotechnology & Medical Research industry. The company's beta value is 1.19. This indicates that the stock tends to outperform the index during upward trending markets but experiences larger declines during downward trending markets. with an industry-leading ESG disclosure.

Score

Industry at a Glance

Previous score
4.22
Change
0
Beta vs S&P 500 index
1.18
VaR
+7.20%
240-Day Maximum Drawdown
+37.16%
240-Day Volatility
+78.72%

Return

Best Daily Return
60 days
+10.94%
120 days
+12.08%
5 years
+58.31%
Worst Daily Return
60 days
-9.02%
120 days
-10.44%
5 years
-32.11%
Sharpe Ratio
60 days
+0.05
120 days
+0.48
5 years
+0.42

Risk Assessment

Maximum Drawdown
240 days
+37.16%
3 years
+71.89%
5 years
+89.03%
Return-to-Drawdown Ratio
240 days
+5.48
3 years
+0.84
5 years
+0.03
Skewness
240 days
+1.13
3 years
+2.22
5 years
+1.53

Volatility

Realised Volatility
240 days
+78.72%
5 years
+85.78%
Standardised True Range
240 days
+5.74%
5 years
+3.56%
Downside Risk-Adjusted Return
120 days
+83.80%
240 days
+83.80%
Maximum Daily Upside Volatility
60 days
+44.53%
Maximum Daily Downside Volatility
60 days
+38.39%

Liquidity

Average Turnover Rate
60 days
+1.33%
120 days
+1.38%
5 years
--
Turnover Deviation
20 days
-35.46%
60 days
-8.88%
120 days
-5.42%

Peer Comparison

Biotechnology & Medical Research
Stoke Therapeutics Inc
Stoke Therapeutics Inc
STOK
7.15 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Krystal Biotech Inc
Krystal Biotech Inc
KRYS
8.57 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
BioCryst Pharmaceuticals Inc
BioCryst Pharmaceuticals Inc
BCRX
8.57 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Ascendis Pharma A/S
Ascendis Pharma A/S
ASND
8.48 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Exelixis Inc
Exelixis Inc
EXEL
8.44 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Alkermes Plc
Alkermes Plc
ALKS
8.44 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
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