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Stoke Therapeutics Inc

STOK
32.400USD
+1.920+6.30%
Close 02/06, 16:00ETQuotes delayed by 15 min
1.79BMarket Cap
45.65P/E TTM

Stoke Therapeutics Inc

32.400
+1.920+6.30%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Stoke Therapeutics Inc

Currency: USD Updated: 2026-02-06

Key Insights

Stoke Therapeutics Inc's fundamentals are relatively very healthy, with an industry-leading ESG disclosure.and its growth potential is significant.Its valuation is considered fairly valued, ranking 26 out of 392 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Buy, with the highest price target at 38.44.In the medium term, the stock price is expected to trend up.Despite an average stock market performance over the past month, the company shows strong fundamentals and technicals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Stoke Therapeutics Inc's Score

Industry at a Glance

Industry Ranking
26 / 392
Overall Ranking
121 / 4521
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Media Coverage

Last 24 hours
Coverage Level

Very Low
Very High
Neutral

Stoke Therapeutics Inc Highlights

StrengthsRisks
Stoke Therapeutics, Inc. is a biotechnology company dedicated to addressing the underlying cause of severe diseases by upregulating protein expression with ribonucleic acid (RNA)-based medicines. The Company, through its proprietary Targeted Augmentation of Nuclear Gene Output (TANGO) approach, is engaged in developing antisense oligonucleotides (ASOs) to selectively restore protein levels. Its first compound, zorevunersen (STK-002), is in clinical testing for the treatment of Dravet syndrome, a severe and progressive genetic epilepsy. TANGO aims to restore missing proteins by increasing or stoking protein output from healthy genes, thus compensating for the non-functioning copy of the gene. The Company is pursuing the development of STK-002 for the treatment of autosomal dominant optic atrophy (ADOA), the most common inherited optic nerve disorder. The Company’s initial focus is haploinsufficiency and diseases of the central nervous system and the eye.
High Growth
The company's revenue has grown steadily over the past 3 years, averaging 194.68% year-on-year.
Growing
The company is in a growing phase, with the latest annual income totaling USD 36.55M.
Overvalued
The company’s latest PE is 45.65, at a high 3-year percentile range.
Institutional Selling
The latest institutional holdings are 69.94M shares, decreasing 5.77% quarter-over-quarter.
Held by Invesco
Star Investor Invesco holds 184.75K shares of this stock.

Analyst Rating

Based on 10 analysts
Buy
Current Rating
38.444
Target Price
+26.13%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Financial Health

Currency: USD Updated: 2026-02-06

The current financial score of Stoke Therapeutics Inc is 7.39, ranking 115 out of 392 in the Biotechnology & Medical Research industry. Its financial status is robust, and its operating efficiency is average. Its latest quarterly revenue reached 10.63M, representing a year-over-year increase of 117.25%, while its net profit experienced a year-over-year increase of 45.09%.

Score

Industry at a Glance

Previous score
7.39
Change
0

Financials

9.44

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

7.41

Operational Efficiency

7.59

Growth Potential

5.40

Shareholder Returns

7.11

Stoke Therapeutics Inc's Company Valuation

Currency: USD Updated: 2026-02-06

The current valuation score of Stoke Therapeutics Inc is 5.39, ranking 379 out of 392 in the Biotechnology & Medical Research industry. Its current P/E ratio is 45.65, which is 8.70% below the recent high of 49.62 and 116.94% above the recent low of -7.73.

Score

Industry at a Glance

Previous score
5.39
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 26/392
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2026-02-06

The current earnings forecast score of Stoke Therapeutics Inc is 8.80, ranking 48 out of 392 in the Biotechnology & Medical Research industry. The average price target is 33.50, with a high of 39.00 and a low of 24.00.

Score

Industry at a Glance

Previous score
8.80
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 11 analysts
Buy
Current Rating
35.750
Target Price
+11.72%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

542
Total
6
Median
6
Average
Company name
Ratings
Analysts
Stoke Therapeutics Inc
STOK
11
CRISPR Therapeutics AG
CRSP
29
argenx SE
ARGX
26
IQVIA Holdings Inc
IQV
26
Beigene Ltd
ONC
24
Intellia Therapeutics Inc
NTLA
24
1
2
3
...
109

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2026-02-06

The current price momentum score of Stoke Therapeutics Inc is 9.36, ranking 13 out of 392 in the Biotechnology & Medical Research industry. Currently, the stock price is trading between the resistance level at 36.18 and the support level at 26.92, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
8.95
Change
0.41

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(1)
Neutral(3)
Buy(3)
Indicators
Value
Direction
MACD(12,26,9)
0.534
Neutral
RSI(14)
54.759
Neutral
STOCH(KDJ)(9,3,3)
55.876
Neutral
ATR(14)
2.082
High Vlolatility
CCI(14)
113.373
Buy
Williams %R
27.748
Buy
TRIX(12,20)
-0.085
Sell
StochRSI(14)
47.694
Buy
Moving Average
Sell(0)
Neutral(0)
Buy(6)
Indicators
Value
Direction
MA5
31.888
Buy
MA10
30.901
Buy
MA20
30.427
Buy
MA50
31.449
Buy
MA100
29.560
Buy
MA200
21.400
Buy

Institutional Confidence

Currency: USD Updated: 2026-02-06

The current institutional shareholding score of Stoke Therapeutics Inc is 10.00, ranking 1 out of 392 in the Biotechnology & Medical Research industry. The latest institutional shareholding proportion is 122.44%, representing a quarter-over-quarter increase of 6.06%. The largest institutional shareholder is The Vanguard, holding a total of 3.14M shares, representing 5.50% of shares outstanding, with 8.05% increase in holdings.

Score

Industry at a Glance

Previous score
10.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
Fidelity Management & Research Company LLC
5.93M
-0.40%
Lynx1 Capital Advisors LLC
5.40M
--
RTW Investments L.P.
5.12M
--
Baker Bros. Advisors LP
4.63M
--
Redmile Group, LLC
4.18M
-4.58%
Morgan Stanley & Co. LLC
3.48M
+3.02%
BlackRock Institutional Trust Company, N.A.
3.30M
+10.83%
TD Securities, Inc.
3.17M
--
The Vanguard Group, Inc.
Star Investors
3.15M
+7.30%
Skorpios Trust
2.26M
--
1
2

Risk Assessment

Currency: USD Updated: 2026-02-06

The U.S. Dollar Index is currently in a neutral state, which has a neutral effect on the Biotechnology & Medical Research domestic-focused industry. The Dollar Index (DXY) measures the value of the U.S. dollar against a basket of major currencies, including the euro, yen, pound sterling, Canadian dollar, Swedish krona, and Swiss franc. The current risk assessment score of Stoke Therapeutics Inc is 4.22, ranking 98 out of 392 in the Biotechnology & Medical Research industry. The company's beta value is 1.11. This indicates that the stock tends to outperform the index during upward trending markets but experiences larger declines during downward trending markets. with an industry-leading ESG disclosure.

Score

Industry at a Glance

Previous score
4.22
Change
0
Beta vs S&P 500 index
1.09
VaR
+7.18%
240-Day Maximum Drawdown
+37.16%
240-Day Volatility
+82.89%

Return

Best Daily Return
60 days
+12.25%
120 days
+15.16%
5 years
+58.31%
Worst Daily Return
60 days
-10.44%
120 days
-13.12%
5 years
-32.11%
Sharpe Ratio
60 days
+2.41
120 days
+2.26
5 years
+0.39

Risk Assessment

Maximum Drawdown
240 days
+37.16%
3 years
+75.62%
5 years
+91.80%
Return-to-Drawdown Ratio
240 days
+7.57
3 years
+1.43
5 years
-0.01
Skewness
240 days
+0.85
3 years
+2.06
5 years
+1.53

Volatility

Realised Volatility
240 days
+82.89%
5 years
+85.27%
Standardised True Range
240 days
+4.06%
5 years
+3.27%
Downside Risk-Adjusted Return
120 days
+367.14%
240 days
+367.14%
Maximum Daily Upside Volatility
60 days
+60.86%
Maximum Daily Downside Volatility
60 days
+54.14%

Liquidity

Average Turnover Rate
60 days
+1.37%
120 days
+1.46%
5 years
--
Turnover Deviation
20 days
+17.93%
60 days
-1.84%
120 days
+4.52%

Peer Comparison

Biotechnology & Medical Research
Stoke Therapeutics Inc
Stoke Therapeutics Inc
STOK
7.71 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Alkermes Plc
Alkermes Plc
ALKS
8.60 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Ascendis Pharma A/S
Ascendis Pharma A/S
ASND
8.53 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Ionis Pharmaceuticals Inc
Ionis Pharmaceuticals Inc
IONS
8.38 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
IQVIA Holdings Inc
IQVIA Holdings Inc
IQV
8.37 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
BioCryst Pharmaceuticals Inc
BioCryst Pharmaceuticals Inc
BCRX
8.17 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
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