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Soleno Therapeutics Inc

SLNO
41.530USD
+1.950+4.93%
Close 02/06, 16:00ETQuotes delayed by 15 min
2.23BMarket Cap
LossP/E TTM

Soleno Therapeutics Inc

41.530
+1.950+4.93%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Soleno Therapeutics Inc

Currency: USD Updated: 2026-02-06

Key Insights

Soleno Therapeutics Inc's fundamentals are relatively very healthy, with an industry-leading ESG disclosure.and its growth potential is high.Its valuation is considered fairly valued, ranking 10 out of 392 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Buy, with the highest price target at 111.92.In the medium term, the stock price is expected to trend down.Despite an average stock market performance over the past month, the company shows strong fundamentals and technicals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Soleno Therapeutics Inc's Score

Industry at a Glance

Industry Ranking
10 / 392
Overall Ranking
90 / 4521
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Media Coverage

Last 24 hours
Coverage Level

Very Low
Very High
Negative

Soleno Therapeutics Inc Highlights

StrengthsRisks
Soleno Therapeutics, Inc. is a biopharmaceutical company. The Company is focused on developing novel therapeutics for the treatment of rare diseases. The Company’s lead product candidate, diazoxide choline extended-release tablets (DCCR), is for the treatment of Prader-Willi syndrome (PWS) in individuals four years and older who have hyperphagia. DCCR contains diazoxide choline, a potent ATP-sensitive potassium (KATP) channel activator. DCCR tablets consist of the active ingredient diazoxide choline, a choline salt of diazoxide, which is a benzothiadiazine. Its proposed mode of action, with targets in the brain, pancreas and fat tissue, has the potential to broadly impact complex diseases like PWS to reduce appetite, reduce food-seeking, decrease insulin and leptin resistance, and reduce body fat. The Company has Breakthrough Therapy and Fast-Track designations in the United States and Orphan Drug designations in the United States and European Union.
High Profit Growth
The company's net income leads the industry, with the latest annual income totaling USD 0.00.
Undervalued
The company’s latest PE is -23.78, at a low 3-year percentile range.
Institutional Buying
The latest institutional holdings are 67.47M shares, increasing 5.76% quarter-over-quarter.
Held by The Vanguard
Star Investor The Vanguard holds 3.05M shares of this stock.
Higher Market Activity
The company has more investor interest, with a 20-day turnover ratio of 0.73.

Analyst Rating

Based on 13 analysts
Buy
Current Rating
111.923
Target Price
+165.72%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Financial Health

Currency: USD Updated: 2026-02-06

The current financial score of Soleno Therapeutics Inc is 9.17, ranking 14 out of 392 in the Biotechnology & Medical Research industry. Its financial status is robust, and its operating efficiency is high.

Score

Industry at a Glance

Previous score
9.17
Change
0

Financials

9.51

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

8.92

Operational Efficiency

10.00

Growth Potential

9.80

Shareholder Returns

7.62

Soleno Therapeutics Inc's Company Valuation

Currency: USD Updated: 2026-02-06

The current valuation score of Soleno Therapeutics Inc is 6.81, ranking 217 out of 392 in the Biotechnology & Medical Research industry. Its current P/E ratio is -23.78, which is -97.30% below the recent high of -0.64 and -26.85% above the recent low of -30.17.

Score

Industry at a Glance

Previous score
6.81
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 10/392
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2026-02-06

The current earnings forecast score of Soleno Therapeutics Inc is 8.77, ranking 59 out of 392 in the Biotechnology & Medical Research industry. The average price target is 110.00, with a high of 145.00 and a low of 75.00.

Score

Industry at a Glance

Previous score
8.77
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 13 analysts
Buy
Current Rating
111.923
Target Price
+165.72%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

542
Total
6
Median
6
Average
Company name
Ratings
Analysts
Soleno Therapeutics Inc
SLNO
13
CRISPR Therapeutics AG
CRSP
29
argenx SE
ARGX
26
IQVIA Holdings Inc
IQV
26
Intellia Therapeutics Inc
NTLA
24
Beigene Ltd
ONC
24
1
2
3
...
109

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2026-02-06

The current price momentum score of Soleno Therapeutics Inc is 7.49, ranking 67 out of 392 in the Biotechnology & Medical Research industry. Currently, the stock price is trading between the resistance level at 45.62 and the support level at 37.69, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
6.94
Change
0.55

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(1)
Neutral(6)
Buy(0)
Indicators
Value
Direction
MACD(12,26,9)
0.297
Neutral
RSI(14)
45.033
Neutral
STOCH(KDJ)(9,3,3)
48.372
Neutral
ATR(14)
2.181
Low Volatility
CCI(14)
-71.514
Neutral
Williams %R
47.002
Neutral
TRIX(12,20)
-0.472
Sell
StochRSI(14)
54.031
Neutral
Moving Average
Sell(6)
Neutral(0)
Buy(0)
Indicators
Value
Direction
MA5
41.906
Sell
MA10
41.621
Sell
MA20
42.128
Sell
MA50
46.108
Sell
MA100
52.335
Sell
MA200
64.707
Sell

Institutional Confidence

Currency: USD Updated: 2026-02-06

The current institutional shareholding score of Soleno Therapeutics Inc is 10.00, ranking 1 out of 392 in the Biotechnology & Medical Research industry. The latest institutional shareholding proportion is 125.62%, representing a quarter-over-quarter increase of 15.31%. The largest institutional shareholder is PRFDX, holding a total of 3.85M shares, representing 7.16% of shares outstanding, with 52.46% increase in holdings.

Score

Industry at a Glance

Previous score
10.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
Fidelity Management & Research Company LLC
6.53M
+102.30%
Janus Henderson Investors
6.06M
+14.10%
T. Rowe Price Associates, Inc.
Star Investors
3.85M
+12.49%
The Vanguard Group, Inc.
Star Investors
2.80M
+12.79%
BlackRock Institutional Trust Company, N.A.
2.94M
+17.24%
Avoro Capital Advisors LLC
2.58M
+25.75%
Wellington Management Company, LLP
2.31M
+272.30%
Vivo Capital, LLC
2.28M
-42.44%
State Street Investment Management (US)
2.17M
+54.67%
Invesco Advisers, Inc.
1.49M
+213.97%
1
2

Risk Assessment

Currency: USD Updated: 2026-02-06

The U.S. Dollar Index is currently in a neutral state, which has a neutral effect on the Biotechnology & Medical Research domestic-focused industry. The Dollar Index (DXY) measures the value of the U.S. dollar against a basket of major currencies, including the euro, yen, pound sterling, Canadian dollar, Swedish krona, and Swiss franc. The current risk assessment score of Soleno Therapeutics Inc is 4.54, ranking 82 out of 392 in the Biotechnology & Medical Research industry. The company's beta value is -3.16. This indicates that the stock tends to underperform the index during upward trending markets but experiences smaller declines during downward trending markets. with an industry-leading ESG disclosure.

Score

Industry at a Glance

Previous score
4.54
Change
0
Beta vs S&P 500 index
-3.15
VaR
+6.70%
240-Day Maximum Drawdown
+56.42%
240-Day Volatility
+77.65%

Return

Best Daily Return
60 days
+9.75%
120 days
+13.46%
5 years
+504.97%
Worst Daily Return
60 days
-6.03%
120 days
-26.59%
5 years
-26.59%
Sharpe Ratio
60 days
-0.81
120 days
-1.32
5 years
+0.49

Risk Assessment

Maximum Drawdown
240 days
+56.42%
3 years
+56.42%
5 years
+95.49%
Return-to-Drawdown Ratio
240 days
-0.14
3 years
+9.85
5 years
+0.25
Skewness
240 days
+1.29
3 years
+24.58
5 years
+28.21

Volatility

Realised Volatility
240 days
+77.65%
5 years
+123.39%
Standardised True Range
240 days
+8.27%
5 years
+3.97%
Downside Risk-Adjusted Return
120 days
-165.94%
240 days
-165.94%
Maximum Daily Upside Volatility
60 days
+48.81%
Maximum Daily Downside Volatility
60 days
+31.76%

Liquidity

Average Turnover Rate
60 days
+2.83%
120 days
+2.88%
5 years
--
Turnover Deviation
20 days
+73.43%
60 days
+49.07%
120 days
+52.13%

Peer Comparison

Biotechnology & Medical Research
Soleno Therapeutics Inc
Soleno Therapeutics Inc
SLNO
8.02 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Alkermes Plc
Alkermes Plc
ALKS
8.60 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Ascendis Pharma A/S
Ascendis Pharma A/S
ASND
8.53 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Ionis Pharmaceuticals Inc
Ionis Pharmaceuticals Inc
IONS
8.38 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
IQVIA Holdings Inc
IQVIA Holdings Inc
IQV
8.37 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
BioCryst Pharmaceuticals Inc
BioCryst Pharmaceuticals Inc
BCRX
8.17 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
View more
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