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Silence Therapeutics PLC

SLN
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10.390USD
-0.110-1.05%
Close 07/02, 13:00ETQuotes delayed by 15 min
490.76MMarket Cap
LossP/E TTM

TradingKey Stock Score of Silence Therapeutics PLC

Currency: USD Updated: 2026-07-02

Key Insights

Silence Therapeutics PLC's fundamentals are relatively stable, and its growth potential is high.Its valuation is considered fairly valued, ranking 102 out of 387 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Buy, with the highest price target at 34.75.In the medium term, the stock price is expected to trend up.The company has been performing strongly in the stock market over the past month, which is supported by its strong fundamentals and technicals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Silence Therapeutics PLC's Score

Industry at a Glance

Industry Ranking
102 / 387
Overall Ranking
220 / 4565
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Media Coverage

Last 24 hours
Coverage Level

Very Low
Very High
Positive

Silence Therapeutics PLC Highlights

StrengthsRisks
Silence Therapeutics plc is a global clinical-stage biotechnology company engaged in transforming people’s lives by silencing diseases through precision-engineered medicines created with proprietary siRNA (short interfering RNA) technology. The Company leverages its mRNAi GOLD platform to create siRNAs designed to precisely target and silence disease-associated genes in the liver. The Company focuses on areas of high unmet medical need with programs advancing cardiovascular disease, hematology and rare diseases. Divesiran (SLN124) is its wholly owned siRNA product candidate designed to inhibit TMPRSS6 expression in the liver. Zerlasiran is a siRNA molecule designed for the treatment of cardiovascular disease associated with elevated Lp(a), a lipoprotein in the blood. In addition to its wholly owned clinical pipeline, it has a third siRNA product candidate from its mRNAi GOLD platform in Phase I development in an undisclosed indication through its collaboration with AstraZeneca.
Growing
The company is in a growing phase, with the latest annual income totaling USD 559.00K.
High Profit Growth
The company's net income leads the industry, with the latest annual income totaling USD 559.00K.
Overvalued
The company’s latest PE is -6.54, at a high 3-year percentile range.
Institutional Selling
The latest institutional holdings are 19.17M shares, decreasing 39.48% quarter-over-quarter.
Held by Steven Cohen
Star Investor Steven Cohen holds 92.78K shares of this stock.
Higher Market Activity
The company has more investor interest, with a 20-day turnover ratio of 0.88.

Analyst Rating

Based on 7 analysts
Buy
Current Rating
34.750
Target Price
+230.95%
Upside Space

FAQs

How does TradingKey generate the Stock Score of Silence Therapeutics PLC?

The TradingKey Stock Score provides a comprehensive assessment of Silence Therapeutics PLC based on 34 indicators derived from over 100 underlying data points.
These indicators are categorised into six key dimensions: financial health, company profile, earnings forecasts, price momentum, institutional confidence, and risk assessment, collectively providing investors with a thorough analysis of Silence Therapeutics PLC’s performance and outlook.

How do we generate the financial health score of Silence Therapeutics PLC?

To generate the financial health score of Silence Therapeutics PLC, we analyse various key financial indicators across several core dimensions, including financial fundamentals, earnings quality, operational efficiency, growth potential, and shareholder returns.
By integrating these comprehensive data, the financial health score not only reflects Silence Therapeutics PLC's overall stability, operational efficiency, and growth potential but also captures the investment returns delivered to shareholders. This score aims to support rational decision-making for investors and other stakeholders. A higher score indicates a better financial health of Silence Therapeutics PLC.

How do we generate the company valuation score of Silence Therapeutics PLC?

To generate the company valuation score of Silence Therapeutics PLC, we use several key financial ratios, including P/E, P/B, P/S, and P/CF. These metrics compare Silence Therapeutics PLC’s market value to its earnings, assets, sales, and cash flow, serving as core indicators for assessing company value.
By analysing these ratios in an all-round manner, the valuation score reflects not only the market’s current perception of Silence Therapeutics PLC’s value but also its future profitability and growth potential, thereby supporting more informed investment decisions. A higher score indicates a fairer valuation of Silence Therapeutics PLC.

How do we generate the earnings forecast score of Silence Therapeutics PLC?

To calculate the earnings forecast score of Silence Therapeutics PLC, we consider various key indicators such as analyst ratings, financial forecasts, support and resistance levels, and peer comparisons:
Current ratings and price targets directly reflect analysts’ expectations, while the upside space indicates their views on the stock’s growth potential.
Financial metrics like earnings per share (EPS), revenue, net income, and earnings before interest and taxes (EBIT) are core measures for assessing profitability.
By analysing the high, median, and low ranges of the target price, we can identify price trends and determine key support and resistance levels.
Comparing these indicators against peers provides context for the stock’s performance and helps anchor more realistic expectations.
These factors together form a comprehensive earnings forecast score that accurately reflects the stock’s expected financial performance and growth potential. A higher score suggests that analysts have a more optimistic outlook on Silence Therapeutics PLC’s future.

How do we generate the price momentum score of Silence Therapeutics PLC?

When generating the price momentum score for Silence Therapeutics PLC, we examine momentum indicators including support and resistance levels as well as volume metrics.
Support levels represent price points where buying interest is strong enough to prevent further declines, while resistance levels indicate prices where selling pressure may hinder upward movement. By analysing typical price volume alongside total volume, we assess overall market activity and liquidity. These indicators help identify price trends and potential shifts, enabling more accurate predictions of future earnings.
This comprehensive approach can reflect market sentiment and enable rational forecasts of Silence Therapeutics PLC’s prices. A higher score indicates a more stable short-term price trend for Silence Therapeutics PLC.

How do we generate the institutional confidence score of Silence Therapeutics PLC?

To generate the institutional confidence score of Silence Therapeutics PLC, we analyse both the proportion of shares held by institutions and the number of shares they own. A higher institutional ownership percentage indicates strong confidence of professional investors, which is generally a positive signal about Silence Therapeutics PLC’s potential. By examining the number of shares held, we gain deeper insight into institutions’ commitment and attitude toward the stock, as institutional investors typically conduct thorough analysis before making investment decisions. Understanding institutional confidence helps us refine earnings forecasts and provides a more reliable perspective on the company’s future performance and market stability. A higher score indicates greater institutional endorsement of Silence Therapeutics PLC.

How do we generate the risk management score of Silence Therapeutics PLC?

To assess the risk management score of Silence Therapeutics PLC, we examine multiple key indicators related to returns, risk, volatility, and liquidity.
The highest and lowest daily returns reflect the potential size of gains and losses, while the Sharpe ratio measures risk-adjusted return performance. On the risk side, we analyse maximum drawdown and the return-to-drawdown ratio to identify extreme loss scenarios. Skewness helps assess the distribution of returns and whether performance may be biased. Volatility indicators—such as realised volatility and standardised true range—reveal price fluctuations. Downside risk-adjusted returns provide insight into potential losses and gains. Lastly, liquidity metrics like average turnover rate and turnover deviation indicate how actively the stock is traded.
These indicators together provide a multi-dimensional understanding of Silence Therapeutics PLC’s risk-return profile, serving as core factors of the risk management score. A higher score indicates lower risk on the side of Silence Therapeutics PLC.