Pyxis Oncology, Inc. is a clinical-stage company focused on developing therapeutics to target difficult-to-treat cancers. The Company is building therapeutics that hold the potential for mono and combination therapies. Its clinical program portfolio includes micvotobart pelidotin (MICVO), PYX-106, Sotigalimab (PYX-107), PYX-203, PYX-102, and APX601. The Company’s lead product candidate, MICVO, is an antibody-drug conjugate (ADC) that targets Extradomain-B Fibronectin (EDB+FN), a non-cellular structural component of the tumor extra-cellular matrix (ECM). MICVO is designed to generate a multi-pronged attack on difficult-to-treat cancers by directly killing cancer cells, reducing ECM density, inhibiting tumor angiogenesis and mobilizing an anti-tumor immune response. The Company’s ADC, MICVO, consists of human Immunoglobulin G1 (IgG1) and is site-specifically conjugated with a cleavable linker and a microtubule inhibitor (optimized auristatin) payload.
Growing
The company is in a growing phase, with the latest annual income totaling USD 13.86M.
Fairly Valued
The company’s latest PE is -2.02, at a medium 3-year percentile range.
Institutional Selling
The latest institutional holdings are 25.75M shares, decreasing 34.52% quarter-over-quarter.
Held by Steven Cohen
Star Investor Steven Cohen holds 27.01K shares of this stock.
Higher Market Activity
The company has more investor interest, with a 20-day turnover ratio of 0.45.