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Protagonist Therapeutics Inc

PTGX
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103.880USD
+3.930+3.93%
Close 05/13, 16:00ETQuotes delayed by 15 min
6.68BMarket Cap
LossP/E TTM

Protagonist Therapeutics Inc

103.880
+3.930+3.93%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Protagonist Therapeutics Inc

Currency: USD Updated: 2026-05-12

Key Insights

Protagonist Therapeutics Inc's fundamentals are relatively very healthy, with an industry-leading ESG disclosure.and its growth potential is high.Its valuation is considered fairly valued, ranking 65 out of 383 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Buy, with the highest price target at 117.58.In the medium term, the stock price is expected to trend up.Despite a weak stock market performance over the past month, the company shows strong fundamentals and technicals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Protagonist Therapeutics Inc's Score

Industry at a Glance

Industry Ranking
65 / 383
Overall Ranking
183 / 4490
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Media Coverage

Last 24 hours
Coverage Level

Very Low
Very High
Positive

Protagonist Therapeutics Inc Highlights

StrengthsRisks
Protagonist Therapeutics, Inc. is a biopharmaceutical company focused on peptide therapeutics. The Company’s clinical programs fall into two categories of diseases: hematology and blood disorders, and inflammatory and immunomodulatory diseases. Its two peptides derived from its proprietary discovery technology platform, rusfertide and icotrokinra, are in advanced Phase III clinical development. Its rusfertide (PTG-300) is an injectable hepcidin mimetic in development for the potential treatment of polycythemia vera (PV) and other blood disorders. Icotrokinra, an orally delivered IL-23R specific antagonist for the potential treatment of psoriasis, psoriatic arthritis (PsA), ulcerative colitis and inflammatory bowel disease (IBD) indications. The Company also has a pre-clinical stage oral drug discovery program addressing clinically and commercially validated targets, including the IL-17 oral peptide antagonist PN-881, an oral hepcidin program, and an oral obesity program.
Growing
The company is in a growing phase, with the latest annual income totaling USD 46.02M.
High Profit Growth
The company's net income leads the industry, with the latest annual income totaling USD 46.02M.
Turnaround to Loss
The company's performance has turned to a loss, with the latest annual loss of USD .
Undervalued
The company’s latest PE is -55.40, at a low 3-year percentile range.
Institutional Selling
The latest institutional holdings are 76.23M shares, decreasing 4.07% quarter-over-quarter.
Held by CI Select Canadian Equity Fund
Star Investor CI Select Canadian Equity Fund holds 288.00 shares of this stock.

Analyst Rating

Based on 13 analysts
Buy
Current Rating
117.583
Target Price
+18.34%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Financial Health

Currency: USD Updated: 2026-05-12

The current financial score of Protagonist Therapeutics Inc is 6.39, ranking 247 out of 383 in the Biotechnology & Medical Research industry. Its financial status is robust, and its operating efficiency is low. Its latest quarterly revenue reached 56.37M, representing a year-over-year increase of 99.03%, while its net profit experienced a year-over-year increase of 132.46%.

Score

Industry at a Glance

Previous score
6.39
Change
0

Financials

8.15

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

7.56

Operational Efficiency

2.72

Growth Potential

6.38

Shareholder Returns

7.11

Protagonist Therapeutics Inc's Company Valuation

Currency: USD Updated: 2026-05-12

The current valuation score of Protagonist Therapeutics Inc is 4.19, ranking 375 out of 383 in the Biotechnology & Medical Research industry. Its current P/E ratio is -55.40, which is -321.60% below the recent high of 122.78 and -3.55% above the recent low of -57.37.

Score

Industry at a Glance

Previous score
4.19
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 65/383
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2026-05-12

The current earnings forecast score of Protagonist Therapeutics Inc is 8.46, ranking 121 out of 383 in the Biotechnology & Medical Research industry. The average price target is 91.00, with a high of 115.00 and a low of 65.00.

Score

Industry at a Glance

Previous score
8.46
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 13 analysts
Buy
Current Rating
117.583
Target Price
+13.61%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

554
Total
5
Median
6
Average
Company name
Ratings
Analysts
Protagonist Therapeutics Inc
PTGX
13
CRISPR Therapeutics AG
CRSP
29
IQVIA Holdings Inc
IQV
26
argenx SE
ARGX
26
Beigene Ltd
ONC
25
Ionis Pharmaceuticals Inc
IONS
25
1
2
3
...
111

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2026-05-12

The current price momentum score of Protagonist Therapeutics Inc is 7.17, ranking 127 out of 383 in the Biotechnology & Medical Research industry. Currently, the stock price is trading between the resistance level at 105.63 and the support level at 95.63, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
9.15
Change
-1.98

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(1)
Neutral(2)
Buy(4)
Indicators
Value
Direction
MACD(12,26,9)
0.056
Buy
RSI(14)
54.792
Neutral
STOCH(KDJ)(9,3,3)
64.015
Buy
ATR(14)
4.606
Low Volatility
CCI(14)
94.066
Neutral
Williams %R
23.070
Buy
TRIX(12,20)
-0.049
Sell
StochRSI(14)
98.604
Buy
Moving Average
Sell(0)
Neutral(0)
Buy(6)
Indicators
Value
Direction
MA5
101.108
Buy
MA10
100.558
Buy
MA20
101.653
Buy
MA50
100.349
Buy
MA100
92.490
Buy
MA200
81.593
Buy

Institutional Confidence

Currency: USD Updated: 2026-05-12

The current institutional shareholding score of Protagonist Therapeutics Inc is 10.00, ranking 1 out of 383 in the Biotechnology & Medical Research industry. The latest institutional shareholding proportion is 118.60%, representing a quarter-over-quarter decrease of 0.99%. The largest institutional shareholder is PRFDX, holding a total of 1.34M shares, representing 2.09% of shares outstanding, with 1.51% increase in holdings.

Score

Industry at a Glance

Previous score
10.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
BlackRock Institutional Trust Company, N.A.
8.32M
+3.74%
Farallon Capital Management, L.L.C.
6.14M
-0.84%
UBS Financial Services, Inc.
2.77M
+46.12%
RTW Investments L.P.
5.06M
-12.11%
State Street Investment Management (US)
3.20M
+1.07%
Wellington Management Company, LLP
3.17M
+66.18%
Janus Henderson Investors
2.65M
+140.73%
Johnson & Johnson Innovation-JJDC, Inc.
2.45M
--
Geode Capital Management, L.L.C.
1.45M
+2.56%
Woodline Partners LP
1.41M
-2.05%
1
2

Risk Assessment

Currency: USD Updated: 2026-05-12

The U.S. Dollar Index is currently in a neutral state, which has a neutral effect on the Biotechnology & Medical Research domestic-focused industry. The Dollar Index (DXY) measures the value of the U.S. dollar against a basket of major currencies, including the euro, yen, pound sterling, Canadian dollar, Swedish krona, and Swiss franc. The current risk assessment score of Protagonist Therapeutics Inc is 6.39, ranking 25 out of 383 in the Biotechnology & Medical Research industry. The company's beta value is 1.89. This indicates that the stock tends to outperform the index during upward trending markets but experiences larger declines during downward trending markets. Protagonist Therapeutics Inc’s latest ESG disclosure leads the Biotechnology & Medical Research industry, indicating outstanding, compliant performance across environmental management, social responsibility, and governance, which may help mitigate overall risk.

Score

Industry at a Glance

Previous score
6.39
Change
0
Beta vs S&P 500 index
1.89
VaR
+4.85%
240-Day Maximum Drawdown
+16.38%
240-Day Volatility
+48.01%

Return

Best Daily Return
60 days
+7.33%
120 days
+7.33%
5 years
+93.86%
Worst Daily Return
60 days
-5.06%
120 days
-5.06%
5 years
-62.00%
Sharpe Ratio
60 days
+2.12
120 days
+1.09
5 years
+0.62

Risk Assessment

Maximum Drawdown
240 days
+16.38%
3 years
+49.98%
5 years
+85.79%
Return-to-Drawdown Ratio
240 days
+7.23
3 years
+1.71
5 years
+0.24
Skewness
240 days
+3.13
3 years
+3.72
5 years
+3.57

Volatility

Realised Volatility
240 days
+48.01%
5 years
+81.97%
Standardised True Range
240 days
+3.21%
5 years
+1.79%
Downside Risk-Adjusted Return
120 days
+197.26%
240 days
+197.26%
Maximum Daily Upside Volatility
60 days
+33.57%
Maximum Daily Downside Volatility
60 days
+28.43%

Liquidity

Average Turnover Rate
60 days
+1.20%
120 days
+1.30%
5 years
--
Turnover Deviation
20 days
-27.21%
60 days
-18.00%
120 days
-11.51%

Peer Comparison

Biotechnology & Medical Research
Protagonist Therapeutics Inc
Protagonist Therapeutics Inc
PTGX
6.99 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
IQVIA Holdings Inc
IQVIA Holdings Inc
IQV
8.75 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Krystal Biotech Inc
Krystal Biotech Inc
KRYS
8.60 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Alkermes Plc
Alkermes Plc
ALKS
8.54 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Exelixis Inc
Exelixis Inc
EXEL
8.45 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Ascendis Pharma A/S
Ascendis Pharma A/S
ASND
8.45 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
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