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Protagonist Therapeutics Inc

PTGX
84.490USD
+3.820+4.74%
Close 02/06, 16:00ETQuotes delayed by 15 min
5.28BMarket Cap
108.79P/E TTM

Protagonist Therapeutics Inc

84.490
+3.820+4.74%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Protagonist Therapeutics Inc

Currency: USD Updated: 2026-02-06

Key Insights

Protagonist Therapeutics Inc's fundamentals are relatively very healthy, with an industry-leading ESG disclosure.and its growth potential is high.Its valuation is considered fairly valued, ranking 21 out of 392 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Buy, with the highest price target at 100.54.In the medium term, the stock price is expected to remain stable.The company has been performing well in the stock market over the past month, which is supported by its strong fundamentals and technicals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Protagonist Therapeutics Inc's Score

Industry at a Glance

Industry Ranking
21 / 392
Overall Ranking
114 / 4521
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Media Coverage

Last 24 hours
Coverage Level

Very Low
Very High
Positive

Protagonist Therapeutics Inc Highlights

StrengthsRisks
Protagonist Therapeutics, Inc. is a biopharmaceutical company focused on peptide therapeutics. The Company’s clinical programs fall into two categories of diseases: hematology and blood disorders, and inflammatory and immunomodulatory diseases. Its two peptides derived from its proprietary discovery technology platform, rusfertide and icotrokinra, are in advanced Phase III clinical development. Its rusfertide (PTG-300) is an injectable hepcidin mimetic in development for the potential treatment of polycythemia vera (PV) and other blood disorders. Icotrokinra, an orally delivered IL-23R specific antagonist for the potential treatment of psoriasis, psoriatic arthritis (PsA), ulcerative colitis and inflammatory bowel disease (IBD) indications. The Company also has a pre-clinical stage oral drug discovery program addressing clinically and commercially validated targets, including the IL-17 oral peptide antagonist PN-881, an oral hepcidin program, and an oral obesity program.
High Growth
The company's revenue has grown steadily over the past 3 years, averaging 1534.37% year-on-year.
Turnaround to Profit
The company's performance has turned profitable, with the latest annual net income of USD .
Overvalued
The company’s latest PE is 108.79, at a high 3-year percentile range.
Institutional Selling
The latest institutional holdings are 74.52M shares, decreasing 6.60% quarter-over-quarter.
Held by CI Select Canadian Equity Fund
Star Investor CI Select Canadian Equity Fund holds 163.00 shares of this stock.

Analyst Rating

Based on 13 analysts
Buy
Current Rating
100.538
Target Price
+20.69%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Financial Health

Currency: USD Updated: 2026-02-06

The current financial score of Protagonist Therapeutics Inc is 7.97, ranking 67 out of 392 in the Biotechnology & Medical Research industry. Its financial status is robust, and its operating efficiency is high. Its latest quarterly revenue reached 4.71M, representing a year-over-year increase of 0.79%, while its net profit experienced a year-over-year increase of 18.46%.

Score

Industry at a Glance

Previous score
7.97
Change
0

Financials

9.32

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

6.66

Operational Efficiency

10.00

Growth Potential

6.67

Shareholder Returns

7.19

Protagonist Therapeutics Inc's Company Valuation

Currency: USD Updated: 2026-02-06

The current valuation score of Protagonist Therapeutics Inc is 4.19, ranking 386 out of 392 in the Biotechnology & Medical Research industry. Its current P/E ratio is 108.79, which is 12.85% below the recent high of 122.78 and 121.25% above the recent low of -23.11.

Score

Industry at a Glance

Previous score
4.19
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 21/392
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2026-02-06

The current earnings forecast score of Protagonist Therapeutics Inc is 8.46, ranking 116 out of 392 in the Biotechnology & Medical Research industry. The average price target is 91.00, with a high of 115.00 and a low of 65.00.

Score

Industry at a Glance

Previous score
8.46
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 13 analysts
Buy
Current Rating
100.538
Target Price
+20.69%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

542
Total
6
Median
6
Average
Company name
Ratings
Analysts
Protagonist Therapeutics Inc
PTGX
13
CRISPR Therapeutics AG
CRSP
29
argenx SE
ARGX
26
IQVIA Holdings Inc
IQV
26
Beigene Ltd
ONC
24
Intellia Therapeutics Inc
NTLA
24
1
2
3
...
109

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2026-02-06

The current price momentum score of Protagonist Therapeutics Inc is 9.15, ranking 36 out of 392 in the Biotechnology & Medical Research industry. Currently, the stock price is trading between the resistance level at 88.72 and the support level at 78.98, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
7.15
Change
2

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(1)
Neutral(4)
Buy(1)
Indicators
Value
Direction
MACD(12,26,9)
0.453
Neutral
RSI(14)
52.044
Neutral
STOCH(KDJ)(9,3,3)
66.954
Neutral
ATR(14)
3.729
Low Volatility
CCI(14)
73.809
Neutral
Williams %R
19.107
Overbought
TRIX(12,20)
-0.146
Sell
StochRSI(14)
75.511
Buy
Moving Average
Sell(1)
Neutral(0)
Buy(5)
Indicators
Value
Direction
MA5
83.420
Buy
MA10
82.577
Buy
MA20
82.738
Buy
MA50
85.916
Sell
MA100
80.106
Buy
MA200
66.249
Buy

Institutional Confidence

Currency: USD Updated: 2026-02-06

The current institutional shareholding score of Protagonist Therapeutics Inc is 10.00, ranking 1 out of 392 in the Biotechnology & Medical Research industry. The latest institutional shareholding proportion is 119.20%, representing a quarter-over-quarter increase of 3.57%. The largest institutional shareholder is The Vanguard, holding a total of 5.40M shares, representing 8.64% of shares outstanding, with 25.53% increase in holdings.

Score

Industry at a Glance

Previous score
10.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
BlackRock Institutional Trust Company, N.A.
8.02M
-5.13%
Farallon Capital Management, L.L.C.
6.20M
+0.39%
RTW Investments L.P.
5.76M
--
The Vanguard Group, Inc.
Star Investors
4.25M
-2.33%
State Street Investment Management (US)
3.17M
-1.30%
UBS Financial Services, Inc.
1.89M
-24.35%
BVF Partners L.P.
2.56M
-20.25%
Johnson & Johnson Innovation-JJDC, Inc.
2.45M
--
Wellington Management Company, LLP
1.91M
+83.90%
Deep Track Capital LP
1.72M
-47.14%
1
2

Risk Assessment

Currency: USD Updated: 2026-02-06

The U.S. Dollar Index is currently in a neutral state, which has a neutral effect on the Biotechnology & Medical Research domestic-focused industry. The Dollar Index (DXY) measures the value of the U.S. dollar against a basket of major currencies, including the euro, yen, pound sterling, Canadian dollar, Swedish krona, and Swiss franc. The current risk assessment score of Protagonist Therapeutics Inc is 6.39, ranking 27 out of 392 in the Biotechnology & Medical Research industry. The company's beta value is 2.26. This indicates that the stock tends to outperform the index during upward trending markets but experiences larger declines during downward trending markets. Protagonist Therapeutics Inc’s latest ESG disclosure leads the Biotechnology & Medical Research industry, indicating outstanding, compliant performance across environmental management, social responsibility, and governance, which may help mitigate overall risk.

Score

Industry at a Glance

Previous score
6.39
Change
0
Beta vs S&P 500 index
2.24
VaR
+4.85%
240-Day Maximum Drawdown
+31.58%
240-Day Volatility
+58.67%

Return

Best Daily Return
60 days
+4.76%
120 days
+29.77%
5 years
+93.86%
Worst Daily Return
60 days
-4.84%
120 days
-9.00%
5 years
-62.00%
Sharpe Ratio
60 days
+0.88
120 days
+1.80
5 years
+0.69

Risk Assessment

Maximum Drawdown
240 days
+31.58%
3 years
+52.15%
5 years
+85.79%
Return-to-Drawdown Ratio
240 days
+4.27
3 years
+1.97
5 years
+0.43
Skewness
240 days
+5.89
3 years
+3.35
5 years
+3.53

Volatility

Realised Volatility
240 days
+58.67%
5 years
+82.34%
Standardised True Range
240 days
+3.22%
5 years
+1.97%
Downside Risk-Adjusted Return
120 days
+369.88%
240 days
+369.88%
Maximum Daily Upside Volatility
60 days
+20.58%
Maximum Daily Downside Volatility
60 days
+26.36%

Liquidity

Average Turnover Rate
60 days
+1.27%
120 days
+1.60%
5 years
--
Turnover Deviation
20 days
-20.07%
60 days
-5.18%
120 days
+19.82%

Peer Comparison

Biotechnology & Medical Research
Protagonist Therapeutics Inc
Protagonist Therapeutics Inc
PTGX
7.78 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Alkermes Plc
Alkermes Plc
ALKS
8.60 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Ascendis Pharma A/S
Ascendis Pharma A/S
ASND
8.53 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Ionis Pharmaceuticals Inc
Ionis Pharmaceuticals Inc
IONS
8.38 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
IQVIA Holdings Inc
IQVIA Holdings Inc
IQV
8.37 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
BioCryst Pharmaceuticals Inc
BioCryst Pharmaceuticals Inc
BCRX
8.17 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
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