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Protagonist Therapeutics Inc

PTGX
85.400USD
+1.200+1.43%
Close 11/21, 16:00ETQuotes delayed by 15 min
5.29BMarket Cap
10.01P/E TTM

Protagonist Therapeutics Inc

85.400
+1.200+1.43%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Protagonist Therapeutics Inc

Currency: USD Updated: 2025-11-21

Key Insights

The company's fundamentals are relatively very healthy. Its valuation is considered fairly valued,and institutional recognition is very high. Over the past 30 days, multiple analysts have rated the company as a Buy. The company is performing well in the stock market, with strong fundamentals and technicals supporting the current trend. The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Protagonist Therapeutics Inc's Score

Industry at a Glance

Industry Ranking
29 / 406
Overall Ranking
93 / 4593
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Analyst Rating

Based on 13 analysts
Buy
Current Rating
90.714
Target Price
+7.74%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Protagonist Therapeutics Inc Highlights

StrengthsRisks
Protagonist Therapeutics, Inc. is a biopharmaceutical company. The Company uses its peptide-based chemical entities rusfertide and JNJ-2113 in different stages of development, all derived from its proprietary discovery technology platform. The Company’s clinical programs fall into two categories of diseases: hematology and blood disorders, and inflammatory and immunomodulatory diseases. Its lead clinical asset, rusfertide (PTG-300), is an injectable hepcidin mimetic in development for the potential treatment of polycythemia vera (PV) and other blood disorders. The Company’s Interleukin-23 receptor (IL-23R) antagonist compound JNJ-2113 is an orally delivered investigational drug that is designed to block biological pathways targeted by marketed injectable antibody drugs. Its PN-943 is a wholly owned investigational orally delivered gut-restricted alpha 4 beta 7 (α4β7) specific integrin antagonist for inflammatory bowel disease (IBD).
High Growth
The company's revenue has grown steadily over the past 3 years, averaging 1534.37% year-on-year.
Turnaround to Profit
The company's performance has turned profitable, with the latest annual net income of USD .
Overvalued
The company’s latest PE is 109.96, at a high 3-year percentile range.
Institutional Selling
The latest institutional holdings are 71.95M shares, decreasing 4.80% quarter-over-quarter.
Held by John Hussman
Star Investor John Hussman holds 21.00K shares of this stock.

Financial Health

Currency: USD Updated: 2025-11-21

The company's current financial score is 8.05, which is higher than the Biotechnology & Medical Research industry's average of 6.92. Its financial status is robust, and its operating efficiency is high. Its latest quarterly revenue reached 4.71M, representing a year-over-year increase of 0.79%, while its net profit experienced a year-over-year increase of 18.46%.

Score

Industry at a Glance

Previous score
8.05
Change
0

Financials

10.00

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

7.58

Operational Efficiency

10.00

Growth Potential

5.42

Shareholder Returns

7.23

Protagonist Therapeutics Inc's Company Valuation

Currency: USD Updated: 2025-11-21

The company’s current valuation score is 4.19, which is lower than the Biotechnology & Medical Research industry's average of 7.05. Its current P/E ratio is 109.96, which is 0.19% below the recent high of 110.17 and 121.02% above the recent low of -23.11.

Score

Industry at a Glance

Previous score
4.19
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 29/406
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2025-11-21

The company’s current earnings forecast score is 8.62, which is higher than the Biotechnology & Medical Research industry's average of 8.01. The average price target for Protagonist Therapeutics Inc is 90.50, with a high of 112.00 and a low of 65.00.

Score

Industry at a Glance

Previous score
8.62
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 13 analysts
Buy
Current Rating
90.714
Target Price
+7.74%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

523
Total
6
Median
6
Average
Company name
Ratings
Analysts
Protagonist Therapeutics Inc
PTGX
13
CRISPR Therapeutics AG
CRSP
30
argenx SE
ARGX
25
Intellia Therapeutics Inc
NTLA
25
IQVIA Holdings Inc
IQV
25
Ionis Pharmaceuticals Inc
IONS
25
1
2
3
...
105

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2025-11-21

The company’s current price momentum score is 9.51, which is higher than the Biotechnology & Medical Research industry's average of 6.80. Sideways: Currently, the stock price is trading between the resistance level at 90.22 and the support level at 77.30, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
9.35
Change
0.16

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(1)
Neutral(4)
Buy(1)
Indicators
Value
Direction
MACD(12,26,9)
-0.156
Neutral
RSI(14)
65.156
Neutral
STOCH(KDJ)(9,3,3)
69.875
Neutral
ATR(14)
3.069
High Vlolatility
CCI(14)
61.694
Neutral
Williams %R
13.467
Overbought
TRIX(12,20)
0.645
Sell
StochRSI(14)
73.418
Buy
Moving Average
Sell(0)
Neutral(0)
Buy(6)
Indicators
Value
Direction
MA5
84.778
Buy
MA10
84.538
Buy
MA20
81.097
Buy
MA50
73.711
Buy
MA100
64.626
Buy
MA200
55.729
Buy

Institutional Confidence

Currency: USD Updated: 2025-11-21

The company’s current institutional recognition score is 10.00, which is higher than the Biotechnology & Medical Research industry's average of 5.13. The latest institutional shareholding proportion is 115.09%, representing a quarter-over-quarter increase of 5.29%. The largest institutional shareholder is The Vanguard, holding a total of 4.25M shares, representing 6.79% of shares outstanding, with 3.85% decrease in holdings.

Score

Industry at a Glance

Previous score
10.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
BlackRock Institutional Trust Company, N.A.
8.46M
-1.63%
Farallon Capital Management, L.L.C.
6.17M
+1.06%
RTW Investments L.P.
5.76M
+0.64%
The Vanguard Group, Inc.
Star Investors
4.35M
+1.88%
State Street Investment Management (US)
3.21M
+18.51%
BVF Partners L.P.
3.21M
+24.70%
Johnson & Johnson Innovation-JJDC, Inc.
2.45M
--
Wellington Management Company, LLP
1.04M
+5.10%
UBS Financial Services, Inc.
2.50M
+619.02%
Deep Track Capital LP
3.25M
-0.13%
1
2

Risk Assessment

Currency: USD Updated: 2025-11-21

The company’s current risk assessment score is 6.10, which is higher than the Biotechnology & Medical Research industry's average of 3.47. The company's beta value is 2.23. This indicates that the stock tends to outperform the index during upward trending markets but experiences larger declines during downward trending markets.

Score

Industry at a Glance

Previous score
6.10
Change
0
Beta vs S&P 500 index
2.23
VaR
+5.05%
240-Day Maximum Drawdown
+31.58%
240-Day Volatility
+59.24%

Return

Best Daily Return
60 days
+29.77%
120 days
+29.77%
5 years
+93.86%
Worst Daily Return
60 days
-9.00%
120 days
-9.16%
5 years
-62.00%
Sharpe Ratio
60 days
+2.18
120 days
+2.15
5 years
+0.73

Risk Assessment

Maximum Drawdown
240 days
+31.58%
3 years
+52.15%
5 years
+85.79%
Return-to-Drawdown Ratio
240 days
+3.26
3 years
+4.00
5 years
+0.53
Skewness
240 days
+5.87
3 years
+4.74
5 years
+3.45

Volatility

Realised Volatility
240 days
+59.24%
5 years
+83.27%
Standardised True Range
240 days
+2.79%
5 years
+1.88%
Downside Risk-Adjusted Return
120 days
+384.38%
240 days
+384.38%
Maximum Daily Upside Volatility
60 days
+80.15%
Maximum Daily Downside Volatility
60 days
+35.84%

Liquidity

Average Turnover Rate
60 days
+1.27%
120 days
+1.60%
5 years
--
Turnover Deviation
20 days
-20.07%
60 days
-5.18%
120 days
+19.82%

Peer Comparison

Biotechnology & Medical Research
Protagonist Therapeutics Inc
Protagonist Therapeutics Inc
PTGX
7.88 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
IQVIA Holdings Inc
IQVIA Holdings Inc
IQV
8.78 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Ascendis Pharma A/S
Ascendis Pharma A/S
ASND
8.61 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Zymeworks Inc
Zymeworks Inc
ZYME
8.55 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Dynavax Technologies Corp
Dynavax Technologies Corp
DVAX
8.53 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Exact Sciences Corp
Exact Sciences Corp
EXAS
8.52 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
View more

FAQs

How does TradingKey generate the Stock Score of Protagonist Therapeutics Inc?

The TradingKey Stock Score provides a comprehensive assessment of Protagonist Therapeutics Inc based on 34 indicators derived from over 100 underlying data points.
These indicators are categorised into six key dimensions: financial health, company profile, earnings forecasts, price momentum, institutional confidence, and risk assessment, collectively providing investors with a thorough analysis of Protagonist Therapeutics Inc’s performance and outlook.

How do we generate the financial health score of Protagonist Therapeutics Inc?

To generate the financial health score of Protagonist Therapeutics Inc, we analyse various key financial indicators across several core dimensions, including financial fundamentals, earnings quality, operational efficiency, growth potential, and shareholder returns.
By integrating these comprehensive data, the financial health score not only reflects Protagonist Therapeutics Inc's overall stability, operational efficiency, and growth potential but also captures the investment returns delivered to shareholders. This score aims to support rational decision-making for investors and other stakeholders. A higher score indicates a better financial health of Protagonist Therapeutics Inc.

How do we generate the company valuation score of Protagonist Therapeutics Inc?

To generate the company valuation score of Protagonist Therapeutics Inc, we use several key financial ratios, including P/E, P/B, P/S, and P/CF. These metrics compare Protagonist Therapeutics Inc’s market value to its earnings, assets, sales, and cash flow, serving as core indicators for assessing company value.
By analysing these ratios in an all-round manner, the valuation score reflects not only the market’s current perception of Protagonist Therapeutics Inc’s value but also its future profitability and growth potential, thereby supporting more informed investment decisions. A higher score indicates a fairer valuation of Protagonist Therapeutics Inc.

How do we generate the earnings forecast score of Protagonist Therapeutics Inc?

To calculate the earnings forecast score of Protagonist Therapeutics Inc, we consider various key indicators such as analyst ratings, financial forecasts, support and resistance levels, and peer comparisons:
Current ratings and price targets directly reflect analysts’ expectations, while the upside space indicates their views on the stock’s growth potential.
Financial metrics like earnings per share (EPS), revenue, net income, and earnings before interest and taxes (EBIT) are core measures for assessing profitability.
By analysing the high, median, and low ranges of the target price, we can identify price trends and determine key support and resistance levels.
Comparing these indicators against peers provides context for the stock’s performance and helps anchor more realistic expectations.
These factors together form a comprehensive earnings forecast score that accurately reflects the stock’s expected financial performance and growth potential. A higher score suggests that analysts have a more optimistic outlook on Protagonist Therapeutics Inc’s future.

How do we generate the price momentum score of Protagonist Therapeutics Inc?

When generating the price momentum score for Protagonist Therapeutics Inc, we examine momentum indicators including support and resistance levels as well as volume metrics.
Support levels represent price points where buying interest is strong enough to prevent further declines, while resistance levels indicate prices where selling pressure may hinder upward movement. By analysing typical price volume alongside total volume, we assess overall market activity and liquidity. These indicators help identify price trends and potential shifts, enabling more accurate predictions of future earnings.
This comprehensive approach can reflect market sentiment and enable rational forecasts of Protagonist Therapeutics Inc’s prices. A higher score indicates a more stable short-term price trend for Protagonist Therapeutics Inc.

How do we generate the institutional confidence score of Protagonist Therapeutics Inc?

To generate the institutional confidence score of Protagonist Therapeutics Inc, we analyse both the proportion of shares held by institutions and the number of shares they own. A higher institutional ownership percentage indicates strong confidence of professional investors, which is generally a positive signal about Protagonist Therapeutics Inc’s potential. By examining the number of shares held, we gain deeper insight into institutions’ commitment and attitude toward the stock, as institutional investors typically conduct thorough analysis before making investment decisions. Understanding institutional confidence helps us refine earnings forecasts and provides a more reliable perspective on the company’s future performance and market stability. A higher score indicates greater institutional endorsement of Protagonist Therapeutics Inc.

How do we generate the risk management score of Protagonist Therapeutics Inc?

To assess the risk management score of Protagonist Therapeutics Inc, we examine multiple key indicators related to returns, risk, volatility, and liquidity.
The highest and lowest daily returns reflect the potential size of gains and losses, while the Sharpe ratio measures risk-adjusted return performance. On the risk side, we analyse maximum drawdown and the return-to-drawdown ratio to identify extreme loss scenarios. Skewness helps assess the distribution of returns and whether performance may be biased. Volatility indicators—such as realised volatility and standardised true range—reveal price fluctuations. Downside risk-adjusted returns provide insight into potential losses and gains. Lastly, liquidity metrics like average turnover rate and turnover deviation indicate how actively the stock is traded.
These indicators together provide a multi-dimensional understanding of Protagonist Therapeutics Inc’s risk-return profile, serving as core factors of the risk management score. A higher score indicates lower risk on the side of Protagonist Therapeutics Inc.
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