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Prothena Corporation PLC

PRTA
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9.680USD
-0.180-1.83%
Market hours ETQuotes delayed by 15 min
513.79MMarket Cap
LossP/E TTM

Prothena Corporation PLC

9.680
-0.180-1.83%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Prothena Corporation PLC

Currency: USD Updated: 2026-05-14

Key Insights

Prothena Corporation PLC's fundamentals are relatively very healthy, with an industry-leading ESG disclosure.and its growth potential is good.Its valuation is considered fairly valued, ranking 94 out of 382 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Hold, with the highest price target at 21.40.In the medium term, the stock price is expected to remain stable.Despite a weak stock market performance over the past month, the company shows strong fundamentals and technicals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Prothena Corporation PLC's Score

Industry at a Glance

Industry Ranking
94 / 382
Overall Ranking
207 / 4482
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Media Coverage

Last 24 hours
Coverage Level

Very Low
Very High
Neutral

Prothena Corporation PLC Highlights

StrengthsRisks
Prothena Corporation plc is an Ireland-based late-stage clinical biotechnology company. The Company is engaged in protein dysregulation and a pipeline of investigational therapeutics for rare peripheral amyloid diseases. The Company is advancing a pipeline of therapeutic candidates for a range of indications and targets to integrate scientific insights around neurological dysfunction and the biology of misfolded proteins. The Company’s pipeline includes both wholly owned and partnered programs being developed for the potential treatment of diseases, including AL amyloidosis, ATTR amyloidosis, Alzheimer’s disease, Parkinson’s disease and a range of other neurodegenerative diseases. Its clinical programs include birtamimab for the potential treatment of AL amyloidosis, prasinezumab for the potential treatment of Parkinson’s disease, NNC6019/PRX004 for the potential treatment of ATTR amyloidosis, and PRX005 and PRX012 for the potential treatment of Alzheimer’s disease.
Growing
The company is in a growing phase, with the latest annual income totaling USD 9.68M.
High Profit Growth
The company's net income leads the industry, with the latest annual income totaling USD 9.68M.
Fairly Valued
The company’s latest PE is -3.51, at a medium 3-year percentile range.
Institutional Selling
The latest institutional holdings are 50.39M shares, decreasing 22.37% quarter-over-quarter.
Held by CI Select Canadian Equity Fund
Star Investor CI Select Canadian Equity Fund holds 4.73K shares of this stock.

Analyst Rating

Based on 6 analysts
Hold
Current Rating
21.400
Target Price
+122.92%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Financial Health

Currency: USD Updated: 2026-05-14

The current financial score of Prothena Corporation PLC is 6.20, ranking 274 out of 382 in the Biotechnology & Medical Research industry. Its financial status is robust, and its operating efficiency is low. Its latest quarterly revenue reached 51.08M, representing a year-over-year increase of 1706.36%, while its net profit experienced a year-over-year increase of 154.36%.

Score

Industry at a Glance

Previous score
6.20
Change
0

Financials

9.48

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

7.85

Operational Efficiency

2.72

Growth Potential

3.87

Shareholder Returns

7.11

Prothena Corporation PLC's Company Valuation

Currency: USD Updated: 2026-05-14

The current valuation score of Prothena Corporation PLC is 7.12, ranking 161 out of 382 in the Biotechnology & Medical Research industry. Its current P/E ratio is -3.51, which is -69.30% below the recent high of -1.08 and -1015.44% above the recent low of -39.18.

Score

Industry at a Glance

Previous score
7.12
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 94/382
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2026-05-14

The current earnings forecast score of Prothena Corporation PLC is 6.67, ranking 324 out of 382 in the Biotechnology & Medical Research industry. The average price target is 18.50, with a high of 36.00 and a low of 8.00.

Score

Industry at a Glance

Previous score
6.67
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 6 analysts
Hold
Current Rating
21.400
Target Price
+122.92%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

554
Total
5
Median
6
Average
Company name
Ratings
Analysts
Prothena Corporation PLC
PRTA
6
CRISPR Therapeutics AG
CRSP
29
argenx SE
ARGX
26
IQVIA Holdings Inc
IQV
26
Beigene Ltd
ONC
25
Ionis Pharmaceuticals Inc
IONS
25
1
2
3
...
111

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2026-05-14

The current price momentum score of Prothena Corporation PLC is 6.14, ranking 287 out of 382 in the Biotechnology & Medical Research industry. Currently, the stock price is trading between the resistance level at 11.35 and the support level at 8.83, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
5.98
Change
0.16

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(3)
Neutral(2)
Buy(1)
Indicators
Value
Direction
MACD(12,26,9)
-0.400
Neutral
RSI(14)
43.922
Neutral
STOCH(KDJ)(9,3,3)
17.787
Oversold
ATR(14)
0.634
High Vlolatility
CCI(14)
-113.236
Sell
Williams %R
76.984
Sell
TRIX(12,20)
0.015
Sell
StochRSI(14)
42.383
Buy
Moving Average
Sell(4)
Neutral(0)
Buy(2)
Indicators
Value
Direction
MA5
9.858
Sell
MA10
10.361
Sell
MA20
10.620
Sell
MA50
10.041
Sell
MA100
9.617
Buy
MA200
9.497
Buy

Institutional Confidence

Currency: USD Updated: 2026-05-14

The current institutional shareholding score of Prothena Corporation PLC is 10.00, ranking 1 out of 382 in the Biotechnology & Medical Research industry. The latest institutional shareholding proportion is 96.24%, representing a quarter-over-quarter increase of 19.52%. The largest institutional shareholder is Steven Cohen, holding a total of 860.02K shares, representing 1.64% of shares outstanding, with 1.00% increase in holdings.

Score

Industry at a Glance

Previous score
10.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
Fidelity Management & Research Company LLC
7.55M
-4.43%
Scully (William P)
5.28M
-1.31%
Fennell (Todd W.)
4.50M
+3.33%
Rubric Capital Management LP
3.68M
+138.73%
BlackRock Institutional Trust Company, N.A.
3.33M
+12.04%
State Street Investment Management (US)
2.27M
+151.69%
D. E. Shaw & Co., L.P.
1.68M
+27.82%
Armistice Capital LLC
1.50M
-17.76%
Adar1 Capital Management LLC
1.46M
-0.77%
1
2

Risk Assessment

Currency: USD Updated: 2026-05-14

The U.S. Dollar Index is currently in a neutral state, which has a neutral effect on the Biotechnology & Medical Research domestic-focused industry. The Dollar Index (DXY) measures the value of the U.S. dollar against a basket of major currencies, including the euro, yen, pound sterling, Canadian dollar, Swedish krona, and Swiss franc. The current risk assessment score of Prothena Corporation PLC is 5.28, ranking 46 out of 382 in the Biotechnology & Medical Research industry. The company's beta value is -0.24. This indicates that the stock tends to underperform the index during upward trending markets but experiences smaller declines during downward trending markets. with an industry-leading ESG disclosure.

Score

Industry at a Glance

Previous score
5.28
Change
0
Beta vs S&P 500 index
-0.24
VaR
+6.20%
240-Day Maximum Drawdown
+25.25%
240-Day Volatility
+59.54%

Return

Best Daily Return
60 days
+8.42%
120 days
+8.42%
5 years
+87.52%
Worst Daily Return
60 days
-9.88%
120 days
-9.88%
5 years
-30.40%
Sharpe Ratio
60 days
+1.04
120 days
+0.03
5 years
-0.12

Risk Assessment

Maximum Drawdown
240 days
+25.25%
3 years
+93.51%
5 years
+94.19%
Return-to-Drawdown Ratio
240 days
+4.55
3 years
-0.30
5 years
-0.17
Skewness
240 days
+0.70
3 years
+0.30
5 years
+5.24

Volatility

Realised Volatility
240 days
+59.54%
5 years
+74.33%
Standardised True Range
240 days
+4.69%
5 years
+19.03%
Downside Risk-Adjusted Return
120 days
+4.99%
240 days
+4.99%
Maximum Daily Upside Volatility
60 days
+40.14%
Maximum Daily Downside Volatility
60 days
+41.87%

Liquidity

Average Turnover Rate
60 days
+0.94%
120 days
+1.01%
5 years
--
Turnover Deviation
20 days
-38.23%
60 days
-31.05%
120 days
-25.90%

Peer Comparison

Biotechnology & Medical Research
Prothena Corporation PLC
Prothena Corporation PLC
PRTA
6.71 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
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Krystal Biotech Inc
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8.61 /10
Score
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Score
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Score
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