tradingkey.logo

Prime Medicine Inc

PRME

5.120USD

+0.470+10.11%
Close 09/18, 16:00ETQuotes delayed by 15 min
688.61MMarket Cap
LossP/E TTM

Prime Medicine Inc

5.120

+0.470+10.11%

TradingKey Stock Score

Overall Financial Health

Valuation Dimensions

Earnings Forecast

Price Momentum

Institutional Confidence

Risk Assessment

Peer Comparison

TradingKey Stock Score

Overall Financial Health

Valuation Dimensions

Earnings Forecast

Price Momentum

Institutional Confidence

Risk Assessment

Peer Comparison

TradingKey Stock Score

Currency: USD Updated2025-09-18

Key Insights

The company's fundamentals are relatively stable. Its valuation is considered fairly valued,and institutional recognition is very high. Over the past 30 days, multiple analysts have rated the company as a Buy. Despite a very weak stock market performance, the company shows strong technicals. The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Industry Ranking
119 / 506
Overall Ranking
231 / 4721
Industry
Biotechnology & Medical Research

Support & Resistance

No Data

Score Analysis

Current score
Previous score

Analyst Rating

Based on 12 analysts
Buy
Current Rating
7.286
Target Price
+56.68%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Company Highlights

StrengthsRisks
Prime Medicine, Inc. is a biotechnology company engaged in creating and delivering the gene editing therapies to patients. It deploys its Prime Editing platform, a gene editing technology, to develop a new class of differentiated, one-time genetic therapies. It is engaged in developing Prime Editors as a new class of therapeutics with transformative potential to expand the application of curative precision genetic medicines. It has built a diversified portfolio of investigational therapeutic programs organized around core areas of focus, namely hematology and immunology, liver, lung, ocular and neuromuscular. The programs within its other areas of focus are on earlier stages of preclinical development and include Liver programs, such as Wilson's disease and glycogen storage disease 1b; Lung program, such as Cystic fibrosis; Ocular program, such as Retinitis pigmentosa caused by Rhodopsin mutations, and Neuromuscular programs, including Friedreich's ataxia and myotonic dystrophy type 1.
Growing
The company is in a growing phase, with the latest annual income totaling USD 2.98M.
High Profit Growth
The company's net income leads the industry, with the latest annual income totaling USD 37.93.
Fairly Valued
The company’s latest PE is -3.28, at a medium 3-year percentile range.
Institutional Selling
The latest institutional holdings are 104.91M shares, decreasing 15.23% quarter-over-quarter.
Held by The Vanguard
Star Investor The Vanguard holds 3.63M shares of this stock.
Lower Market Activity
The company has less investor interest, with a 20-day turnover ratio of 1.24.

Financial Health

Currency: USD Updated2025-09-18

The company's current financial score is 5.41, which is lower than the Biotechnology & Medical Research industry's average of 6.93. Its financial status is weak, and its operating efficiency is low.

Score

Industry at a Glance

Previous score
5.41
Change
0

Financials

5.08

Key Metrics

Cash and cash equivalents

Total assets

Total liabilities

Free cash flow

No Data

Quality of Earnings

7.33

Operational Efficiency

2.77

Growth Potential

4.80

Shareholder Returns

7.09

Company Valuation

Currency: USD Updated2025-09-18

The company’s current valuation score is 2.80, which is lower than the Biotechnology & Medical Research industry's average of 3.06. Its current P/E ratio is -2.98, which is -31.72% below the recent high of -2.03 and -141.75% above the recent low of -7.20.

Score

Industry at a Glance

Previous score
2.80
Change
0

Valuation Dimensions

P/E

P/B

P/S

P/CF

Industry Ranking 119/506
No Data

Earnings Forecast

Currency: USD Updated2025-09-18

The company’s current earnings forecast score is 7.83, which is lower than the Biotechnology & Medical Research industry's average of 8.03. The average price target for Prime Medicine Inc is 8.00, with a high of 10.00 and a low of 4.00.

Score

Industry at a Glance

Previous score
7.83
Change
0

Support & Resistance

No Data

Analyst Rating

Based on 12 analysts
Buy
Current Rating
7.286
Target Price
+56.68%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

554
Total
5
Median
6
Average
Company name
Ratings
Analysts
Prime Medicine Inc
PRME
12
CRISPR Therapeutics AG
CRSP
30
Intellia Therapeutics Inc
NTLA
26
Exact Sciences Corp
EXAS
26
Ionis Pharmaceuticals Inc
IONS
26
IQVIA Holdings Inc
IQV
25
1
2
3
...
111

Financial Forecasting

EPS

Revenue

Net Profit

EBIT

No Data

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated2025-09-18

The company’s current price momentum score is 8.40, which is higher than the Biotechnology & Medical Research industry's average of 6.32. Sideways: Currently, the stock price is trading between the resistance level at 5.43 and the support level at 3.48, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
8.40
Change
0.34

Support & Resistance

No Data

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(1)
Neutral(0)
Buy(3)
Indicators
Value
Direction
MACD(12,26,9)
0.308
Buy
RSI(14)
72.485
Buy
STOCH(KDJ)(9,3,3)
89.892
Overbought
ATR(14)
0.357
High Vlolatility
CCI(14)
170.427
Buy
Williams %R
2.404
Overbought
TRIX(12,20)
0.747
Sell
StochRSI(14)
100.000
Overbought
Moving Average
Sell(0)
Neutral(0)
Buy(6)
Indicators
Value
Direction
MA5
4.504
Buy
MA10
4.222
Buy
MA20
3.806
Buy
MA50
3.932
Buy
MA100
2.873
Buy
MA200
2.663
Buy

Institutional Confidence

Currency: USD Updated2025-09-18

The company’s current institutional recognition score is 5.00, which is lower than the Biotechnology & Medical Research industry's average of 5.96. The latest institutional shareholding proportion is 62.37%, representing a quarter-over-quarter decrease of 22.90%. The largest institutional shareholder is The Vanguard, holding a total of 3.63M shares, representing 2.07% of shares outstanding, with 25.56% decrease in holdings.

Score

Industry at a Glance

Previous score
5.00
Change
0

Institutional Shareholding

No Data

Shareholder Activity

Name
Shares Held
Chg %
Liu (David R)
20.24M
+0.42%
ARCH Venture Partners
15.46M
--
Alphabet, Inc.
15.06M
--
T. Rowe Price Investment Management, Inc.
4.14M
+4.15%
Newpath Partners LP
6.11M
--
Gottesdiener (Keith Michael)
4.36M
+6.08%
BlackRock Institutional Trust Company, N.A.
3.93M
-3.61%
Fidelity Management & Research Company LLC
3.75M
-1.44%
The Vanguard Group, Inc.
Star Investors
3.64M
-0.38%
ARK Investment Management LLC
Star Investors
3.10M
-39.90%
1
2

Risk Assessment

Currency: USD Updated2025-09-18

The company’s current risk assessment score is 3.06, which is lower than the Biotechnology & Medical Research industry's average of 3.33. The company's beta value is 0.00. This indicates that the stock tends to underperform the index during upward trending markets but experiences smaller declines during downward trending markets.

Score

Industry at a Glance

Previous score
3.06
Change
0
Beta vs S&P 500 index
--
VaR
--
240-Day Maximum Drawdown
+74.22%
240-Day Volatility
+110.45%
Return
Best Daily Return
60 days
+22.19%
120 days
+26.19%
5 years
--
Worst Daily Return
60 days
-10.72%
120 days
-16.04%
5 years
--
Sharpe Ratio
60 days
+3.49
120 days
+2.04
5 years
--
Risk Assessment
Maximum Drawdown
240 days
+74.22%
3 years
+94.55%
5 years
--
Return-to-Drawdown Ratio
240 days
+0.47
3 years
-0.27
5 years
--
Skewness
240 days
+0.71
3 years
+0.60
5 years
--
Volatility
Realised Volatility
240 days
+110.45%
5 years
--
Standardised True Range
240 days
+5.91%
5 years
--
Downside Risk-Adjusted Return
120 days
+423.65%
240 days
+423.65%
Maximum Daily Upside Volatility
60 days
+113.45%
Maximum Daily Downside Volatility
60 days
+75.69%
Liquidity
Average Turnover Rate
60 days
+3.29%
120 days
+2.36%
5 years
--
Turnover Deviation
20 days
+124.02%
60 days
+174.77%
120 days
+97.51%

Peer Comparison

Biotechnology & Medical Research
Prime Medicine Inc
Prime Medicine Inc
PRME
5.89 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Krystal Biotech Inc
Krystal Biotech Inc
KRYS
8.18 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Alkermes Plc
Alkermes Plc
ALKS
7.88 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
ACADIA Pharmaceuticals Inc
ACADIA Pharmaceuticals Inc
ACAD
7.70 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Zymeworks Inc
Zymeworks Inc
ZYME
7.68 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
MiMedx Group Inc
MiMedx Group Inc
MDXG
7.66 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
View more
KeyAI