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Prime Medicine Inc

PRME
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2.930USD
-0.200-6.39%
Close 05/15, 16:00ETQuotes delayed by 15 min
529.21MMarket Cap
LossP/E TTM

Prime Medicine Inc

2.930
-0.200-6.39%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Prime Medicine Inc

Currency: USD Updated: 2026-05-15

Key Insights

Prime Medicine Inc's fundamentals are relatively stable, with an industry-leading ESG disclosure.and its growth potential is significant.Its valuation is considered fairly valued, ranking 155 out of 382 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Buy, with the highest price target at 6.92.In the medium term, the stock price is expected to trend down.The company has shown very weak stock market performance over the past month, in line with its fundamentals and technicals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Prime Medicine Inc's Score

Industry at a Glance

Industry Ranking
155 / 382
Overall Ranking
287 / 4482
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Media Coverage

Last 24 hours
Coverage Level

Very Low
Very High
Negative-

Prime Medicine Inc Highlights

StrengthsRisks
Prime Medicine, Inc. is a biotechnology company engaged in creating and delivering gene editing therapies to patients. It deploys its proprietary Prime Editing platform, a versatile, precise and efficient gene editing technology, to develop a new class of differentiated one-time curative genetic therapies. It is advancing a set of high-value programs across its core areas of focus (hematology, immunology and oncology, liver, and lung). These include ex vivo hematopoietic stem cell (HSC) programs for the treatment of p47phox chronic granulomatous disease CGD and X-linked CGD; a lipid nanoparticle (LNP) Prime Editor for the treatment of Wilson’s Disease; a LNP or adeno-associated virus Prime Editors for the treatment of cystic fibrosis; and ex vivo T-cell therapies. PM359, its product candidate within its hematology, immunology and oncology area of focus, targets the p47phox variant of CGD. Its PM577 comprises a Prime Editor encapsulated as RNA cargo in a liver-targeted LNP.
Growing
The company is in a growing phase, with the latest annual income totaling USD 4.63M.
Fairly Valued
The company’s latest PE is -2.38, at a medium 3-year percentile range.
Institutional Buying
The latest institutional holdings are 123.80M shares, increasing 5.44% quarter-over-quarter.
Held by James Simons
Star Investor James Simons holds 1.15M shares of this stock.

Analyst Rating

Based on 13 analysts
Buy
Current Rating
6.917
Target Price
+120.98%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Financial Health

Currency: USD Updated: 2026-05-15

The current financial score of Prime Medicine Inc is 5.47, ranking 350 out of 382 in the Biotechnology & Medical Research industry. Its financial status is weak, and its operating efficiency is low. Its latest quarterly revenue reached 856.00K, representing a year-over-year decrease of 41.13%, while its net profit experienced a year-over-year decrease of 5.33%.

Score

Industry at a Glance

Previous score
5.47
Change
0

Financials

5.26

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

7.52

Operational Efficiency

2.72

Growth Potential

4.76

Shareholder Returns

7.11

Prime Medicine Inc's Company Valuation

Currency: USD Updated: 2026-05-15

The current valuation score of Prime Medicine Inc is 5.76, ranking 353 out of 382 in the Biotechnology & Medical Research industry. Its current P/E ratio is -2.38, which is -69.94% below the recent high of -0.71 and -508.11% above the recent low of -14.45.

Score

Industry at a Glance

Previous score
5.76
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 155/382
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2026-05-15

The current earnings forecast score of Prime Medicine Inc is 8.00, ranking 161 out of 382 in the Biotechnology & Medical Research industry. The average price target is 6.00, with a high of 9.00 and a low of 4.25.

Score

Industry at a Glance

Previous score
8.00
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 13 analysts
Buy
Current Rating
6.917
Target Price
+120.98%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

554
Total
5
Median
6
Average
Company name
Ratings
Analysts
Prime Medicine Inc
PRME
13
CRISPR Therapeutics AG
CRSP
27
argenx SE
ARGX
26
IQVIA Holdings Inc
IQV
26
Beigene Ltd
ONC
26
Ionis Pharmaceuticals Inc
IONS
25
1
2
3
...
111

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2026-05-15

The current price momentum score of Prime Medicine Inc is 5.87, ranking 298 out of 382 in the Biotechnology & Medical Research industry. Currently, the stock price is trading between the resistance level at 3.66 and the support level at 2.56, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
5.88
Change
-0.01

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(4)
Neutral(1)
Buy(0)
Indicators
Value
Direction
MACD(12,26,9)
-0.097
Sell
RSI(14)
31.887
Neutral
STOCH(KDJ)(9,3,3)
11.959
Oversold
ATR(14)
0.241
High Vlolatility
CCI(14)
-178.143
Sell
Williams %R
100.000
Oversold
TRIX(12,20)
-0.532
Sell
StochRSI(14)
0.000
Sell
Moving Average
Sell(6)
Neutral(0)
Buy(0)
Indicators
Value
Direction
MA5
3.174
Sell
MA10
3.247
Sell
MA20
3.476
Sell
MA50
3.559
Sell
MA100
3.690
Sell
MA200
4.016
Sell

Institutional Confidence

Currency: USD Updated: 2026-05-15

The current institutional shareholding score of Prime Medicine Inc is 5.00, ranking 135 out of 382 in the Biotechnology & Medical Research industry. The latest institutional shareholding proportion is 68.55%, representing a quarter-over-quarter increase of 9.13%. The largest institutional shareholder is Catherine Wood, holding a total of 6.25M shares, representing 3.46% of shares outstanding, with 46.71% increase in holdings.

Score

Industry at a Glance

Previous score
5.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
Liu (David R)
20.24M
--
ARCH Venture Partners
18.49M
+19.61%
Alphabet, Inc.
16.56M
--
Bristol Myers Squibb
11.01M
--
BlackRock Institutional Trust Company, N.A.
7.53M
+46.85%
ARK Investment Management LLC
Star Investors
5.37M
-2.00%
Newpath Partners LP
6.11M
--
T. Rowe Price Investment Management, Inc.
6.00M
-34.96%
State Street Investment Management (US)
5.10M
+292.98%
1
2

Risk Assessment

Currency: USD Updated: 2026-05-15

The U.S. Dollar Index is currently in a neutral state, which has a neutral effect on the Biotechnology & Medical Research domestic-focused industry. The Dollar Index (DXY) measures the value of the U.S. dollar against a basket of major currencies, including the euro, yen, pound sterling, Canadian dollar, Swedish krona, and Swiss franc. The current risk assessment score of Prime Medicine Inc is 3.35, ranking 139 out of 382 in the Biotechnology & Medical Research industry. The company's beta value is 2.32. This indicates that the stock tends to outperform the index during upward trending markets but experiences larger declines during downward trending markets. with an industry-leading ESG disclosure.

Score

Industry at a Glance

Previous score
3.35
Change
0
Beta vs S&P 500 index
2.27
VaR
--
240-Day Maximum Drawdown
+56.07%
240-Day Volatility
+102.50%

Return

Best Daily Return
60 days
+14.67%
120 days
+16.58%
5 years
--
Worst Daily Return
60 days
-9.23%
120 days
-9.23%
5 years
--
Sharpe Ratio
60 days
-0.35
120 days
-0.29
5 years
--

Risk Assessment

Maximum Drawdown
240 days
+56.07%
3 years
+92.37%
5 years
--
Return-to-Drawdown Ratio
240 days
+2.61
3 years
-0.29
5 years
--
Skewness
240 days
+0.86
3 years
+0.69
5 years
--

Volatility

Realised Volatility
240 days
+102.50%
5 years
--
Standardised True Range
240 days
+12.16%
5 years
--
Downside Risk-Adjusted Return
120 days
-58.05%
240 days
-58.05%
Maximum Daily Upside Volatility
60 days
+56.14%
Maximum Daily Downside Volatility
60 days
+46.36%

Liquidity

Average Turnover Rate
60 days
+1.86%
120 days
+2.14%
5 years
--
Turnover Deviation
20 days
-11.48%
60 days
+1.54%
120 days
+16.92%

Peer Comparison

Biotechnology & Medical Research
Prime Medicine Inc
Prime Medicine Inc
PRME
5.84 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Krystal Biotech Inc
Krystal Biotech Inc
KRYS
8.57 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
BioCryst Pharmaceuticals Inc
BioCryst Pharmaceuticals Inc
BCRX
8.57 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Ascendis Pharma A/S
Ascendis Pharma A/S
ASND
8.48 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Exelixis Inc
Exelixis Inc
EXEL
8.44 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Alkermes Plc
Alkermes Plc
ALKS
8.44 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
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