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Praxis Precision Medicines Inc

PRAX
290.100USD
-12.590-4.16%
Close 03/27, 16:00ETQuotes delayed by 15 min
659.81MMarket Cap
LossP/E TTM

Praxis Precision Medicines Inc

290.100
-12.590-4.16%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Praxis Precision Medicines Inc

Currency: USD Updated: 2026-03-27

Key Insights

Praxis Precision Medicines Inc's fundamentals are relatively healthy, with an industry-leading ESG disclosure.and its growth potential is high.Its valuation is considered fairly valued, ranking 83 out of 391 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Buy, with the highest price target at 617.62.In the medium term, the stock price is expected to remain stable.Despite a weak stock market performance over the past month, the company shows strong fundamentals and technicals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Praxis Precision Medicines Inc's Score

Industry at a Glance

Industry Ranking
83 / 391
Overall Ranking
196 / 4542
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Media Coverage

Last 24 hours
Coverage Level

Very Low
Very High
Positive

Praxis Precision Medicines Inc Highlights

StrengthsRisks
Praxis Precision Medicines, Inc. is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal excitation-inhibition imbalance. The Company is applying genetic insights to the discovery and development of therapies for neurological disorders through two platforms, using its understanding of shared biological targets and circuits in the brain. Its platform includes Cerebrum, a small-molecule platform, which utilizes deep understanding of neuronal excitability and neuronal networks and applies a series of computational and experimental tools to develop orally available precision therapies, and Solidus, an antisense oligonucleotide platform, is an efficient, targeted precision medicine discovery and development engine anchored on a proprietary, computational methodology. The Company’s product candidates include ulixacaltamide, vormatrigine, relutrigine, PRAX-080, and others.
High Profit Growth
The company's net income leads the industry, with the latest annual income totaling USD 0.00.
Undervalued
The company’s latest PE is -21.53, at a low 3-year percentile range.
Institutional Selling
The latest institutional holdings are 25.06M shares, decreasing 20.88% quarter-over-quarter.
Held by HOTCHKIS & WILEY
Star Investor HOTCHKIS & WILEY holds 140.00 shares of this stock.

Analyst Rating

Based on 16 analysts
Buy
Current Rating
617.625
Target Price
+104.05%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Financial Health

Currency: USD Updated: 2026-03-27

The current financial score of Praxis Precision Medicines Inc is 6.42, ranking 249 out of 391 in the Biotechnology & Medical Research industry. Its financial status is stable, and its operating efficiency is low. Its latest quarterly revenue reached 0.00, representing a year-over-year decrease of 100.00%, while its net profit experienced a year-over-year decrease of 51.52%.

Score

Industry at a Glance

Previous score
6.42
Change
0

Financials

6.95

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

7.21

Operational Efficiency

2.67

Growth Potential

8.17

Shareholder Returns

7.11

Praxis Precision Medicines Inc's Company Valuation

Currency: USD Updated: 2026-03-27

The current valuation score of Praxis Precision Medicines Inc is 5.94, ranking 349 out of 391 in the Biotechnology & Medical Research industry. Its current P/E ratio is -21.53, which is -99.28% below the recent high of -0.15 and -19.80% above the recent low of -25.79.

Score

Industry at a Glance

Previous score
5.94
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 83/391
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2026-03-27

The current earnings forecast score of Praxis Precision Medicines Inc is 8.24, ranking 152 out of 391 in the Biotechnology & Medical Research industry. The average price target is 340.00, with a high of 760.00 and a low of 65.00.

Score

Industry at a Glance

Previous score
8.24
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 16 analysts
Buy
Current Rating
617.625
Target Price
+104.05%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

548
Total
6
Median
6
Average
Company name
Ratings
Analysts
Praxis Precision Medicines Inc
PRAX
16
CRISPR Therapeutics AG
CRSP
29
IQVIA Holdings Inc
IQV
27
argenx SE
ARGX
26
Intellia Therapeutics Inc
NTLA
24
Beigene Ltd
ONC
24
1
2
3
...
110

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2026-03-27

The current price momentum score of Praxis Precision Medicines Inc is 6.89, ranking 118 out of 391 in the Biotechnology & Medical Research industry. Currently, the stock price is trading between the resistance level at 326.74 and the support level at 269.23, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
7.33
Change
-0.44

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(4)
Neutral(2)
Buy(0)
Indicators
Value
Direction
MACD(12,26,9)
-1.566
Sell
RSI(14)
41.767
Neutral
STOCH(KDJ)(9,3,3)
37.765
Sell
ATR(14)
17.087
Low Volatility
CCI(14)
-85.118
Neutral
Williams %R
86.879
Oversold
TRIX(12,20)
-0.357
Sell
StochRSI(14)
1.165
Sell
Moving Average
Sell(4)
Neutral(0)
Buy(2)
Indicators
Value
Direction
MA5
298.694
Sell
MA10
298.645
Sell
MA20
304.744
Sell
MA50
314.101
Sell
MA100
273.650
Buy
MA200
169.288
Buy

Institutional Confidence

Currency: USD Updated: 2026-03-27

The current institutional shareholding score of Praxis Precision Medicines Inc is 10.00, ranking 1 out of 391 in the Biotechnology & Medical Research industry. The latest institutional shareholding proportion is 91.50%, representing a quarter-over-quarter decrease of 10.71%. The largest institutional shareholder is The Vanguard, holding a total of 1.46M shares, representing 5.23% of shares outstanding, with 1.75% decrease in holdings.

Score

Industry at a Glance

Previous score
10.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
Janus Henderson Investors
2.76M
+9.10%
Perceptive Advisors LLC
1.56M
+14.83%
BlackRock Institutional Trust Company, N.A.
1.42M
+3.38%
The Vanguard Group, Inc.
Star Investors
1.26M
+4.11%
Baker Bros. Advisors LP
689.49K
--
Adage Capital Management, L.P.
1.31M
-45.02%
Cormorant Asset Management, LP
1.00M
-38.46%
Driehaus Capital Management, LLC
500.55K
-5.73%
1
2

Risk Assessment

Currency: USD Updated: 2026-03-27

The U.S. Dollar Index is currently in a neutral state, which has a neutral effect on the Biotechnology & Medical Research domestic-focused industry. The Dollar Index (DXY) measures the value of the U.S. dollar against a basket of major currencies, including the euro, yen, pound sterling, Canadian dollar, Swedish krona, and Swiss franc. The current risk assessment score of Praxis Precision Medicines Inc is 2.04, ranking 253 out of 391 in the Biotechnology & Medical Research industry. The company's beta value is 3.01. This indicates that the stock tends to outperform the index during upward trending markets but experiences larger declines during downward trending markets. with an industry-leading ESG disclosure.

Score

Industry at a Glance

Previous score
2.04
Change
0
Beta vs S&P 500 index
3.01
VaR
+7.79%
240-Day Maximum Drawdown
+36.33%
240-Day Volatility
+132.46%

Return

Best Daily Return
60 days
+7.23%
120 days
+183.71%
5 years
+183.71%
Worst Daily Return
60 days
-5.67%
120 days
-13.33%
5 years
-78.11%
Sharpe Ratio
60 days
-0.17
120 days
+1.96
5 years
+0.60

Risk Assessment

Maximum Drawdown
240 days
+36.33%
3 years
+68.64%
5 years
+96.50%
Return-to-Drawdown Ratio
240 days
+24.10
3 years
+8.55
5 years
-0.03
Skewness
240 days
+12.60
3 years
+13.01
5 years
+8.44

Volatility

Realised Volatility
240 days
+132.46%
5 years
+122.31%
Standardised True Range
240 days
+3.62%
5 years
+2.83%
Downside Risk-Adjusted Return
120 days
+1436.16%
240 days
+1436.16%
Maximum Daily Upside Volatility
60 days
+38.59%
Maximum Daily Downside Volatility
60 days
+38.18%

Liquidity

Average Turnover Rate
60 days
+2.07%
120 days
+2.10%
5 years
--
Turnover Deviation
20 days
-2.71%
60 days
-15.43%
120 days
-14.23%

Peer Comparison

Biotechnology & Medical Research
Praxis Precision Medicines Inc
Praxis Precision Medicines Inc
PRAX
6.73 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Alkermes Plc
Alkermes Plc
ALKS
8.42 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Madrigal Pharmaceuticals Inc
Madrigal Pharmaceuticals Inc
MDGL
8.27 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
BioCryst Pharmaceuticals Inc
BioCryst Pharmaceuticals Inc
BCRX
8.27 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Day One Biopharmaceuticals Inc
Day One Biopharmaceuticals Inc
DAWN
8.26 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
IQVIA Holdings Inc
IQVIA Holdings Inc
IQV
8.21 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
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