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Oruka Therapeutics Inc

ORKA

16.580USD

+0.370+2.28%
Close 09/18, 16:00ETQuotes delayed by 15 min
620.93MMarket Cap
LossP/E TTM

Oruka Therapeutics Inc

16.580

+0.370+2.28%

TradingKey Stock Score

Overall Financial Health

Valuation Dimensions

Earnings Forecast

Price Momentum

Institutional Confidence

Risk Assessment

Peer Comparison

TradingKey Stock Score

Overall Financial Health

Valuation Dimensions

Earnings Forecast

Price Momentum

Institutional Confidence

Risk Assessment

Peer Comparison

TradingKey Stock Score

Currency: USD Updated: 2025-09-18

Key Insights

The company's fundamentals are relatively weak. Its valuation is considered fairly valued,and institutional recognition is very high. Over the past 30 days, multiple analysts have rated the company as a Strong Buy. Despite a weak stock market performance, the company shows strong technicals. The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Industry Ranking
70 / 506
Overall Ranking
170 / 4721
Industry
Biotechnology & Medical Research

Support & Resistance

No Data

Score Analysis

Current score
Previous score

Analyst Rating

Based on 10 analysts
Strong Buy
Current Rating
43.143
Target Price
+166.15%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Company Highlights

StrengthsRisks
Oruka Therapeutics, Inc., formerly ARCA biopharma, Inc., is a biotechnology company. The Company is engaged in developing novel biologics designed for the treatment of chronic skin diseases, including plaque psoriasis. It is advancing a proprietary portfolio of potential antibodies that target the core mechanisms underlying plaque psoriasis and other dermatologic and inflammatory diseases. The Company’s lead programs include ORKA-001 and ORKA-002, which are designed to block cytokines in the pathogenesis of psoriasis and other inflammatory diseases. ORKA-001 is a potentially monoclonal antibody designed to inhibit IL-23p19 for the treatment of psoriasis. ORKA-001 targets the p19 subunit of interleukin-23 (IL-23p19). ORKA-002 is a potentially monoclonal antibody designed to inhibit IL-17A/F for the treatment of psoriasis, psoriatic arthritis, and other conditions. ORKA-002 targets interleukin-17A and interleukin-17F (IL-17A/F).
High Profit Growth
The company's net income leads the industry, with the latest annual income totaling USD 743.48.
Undervalued
The company’s latest PE is -7.55, at a low 3-year percentile range.
Institutional Selling
The latest institutional holdings are 34.13M shares, decreasing 1.09% quarter-over-quarter.
Held by The Vanguard
Star Investor The Vanguard holds 1.82M shares of this stock.

Financial Health

Currency: USD Updated: 2025-09-18

The company's current financial score is 5.81, which is lower than the Biotechnology & Medical Research industry's average of 6.93. Its financial status is weak, and its operating efficiency is low.

Score

Industry at a Glance

Previous score
5.81
Change
0

Financials

3.69

Key Metrics

Cash and cash equivalents

Total assets

Total liabilities

Free cash flow

No Data

Quality of Earnings

7.58

Operational Efficiency

4.00

Growth Potential

6.75

Shareholder Returns

7.03

Company Valuation

Currency: USD Updated: 2025-09-18

The company’s current valuation score is 2.80, which is lower than the Biotechnology & Medical Research industry's average of 3.06. Its current P/E ratio is -7.38, which is -69.17% below the recent high of -2.27 and 58.46% above the recent low of -3.06.

Score

Industry at a Glance

Previous score
2.80
Change
0

Valuation Dimensions

P/E

P/B

P/S

P/CF

Industry Ranking 70/506
No Data

Earnings Forecast

Currency: USD Updated: 2025-09-18

The company’s current earnings forecast score is 9.20, which is higher than the Biotechnology & Medical Research industry's average of 8.03. The average price target for Oruka Therapeutics Inc is 44.00, with a high of 47.00 and a low of 26.00.

Score

Industry at a Glance

Previous score
9.20
Change
0

Support & Resistance

No Data

Analyst Rating

Based on 10 analysts
Strong Buy
Current Rating
43.143
Target Price
+166.15%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

554
Total
5
Median
6
Average
Company name
Ratings
Analysts
Oruka Therapeutics Inc
ORKA
10
CRISPR Therapeutics AG
CRSP
30
Ionis Pharmaceuticals Inc
IONS
26
Intellia Therapeutics Inc
NTLA
26
Exact Sciences Corp
EXAS
26
IQVIA Holdings Inc
IQV
25
1
2
3
...
111

Financial Forecasting

EPS

Revenue

Net Profit

EBIT

No Data

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2025-09-18

The company’s current price momentum score is 7.27, which is higher than the Biotechnology & Medical Research industry's average of 6.32. Sideways: Currently, the stock price is trading between the resistance level at 18.44 and the support level at 14.04, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
7.27
Change
0.13

Support & Resistance

No Data

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(1)
Neutral(3)
Buy(3)
Indicators
Value
Direction
MACD(12,26,9)
0.025
Buy
RSI(14)
59.729
Neutral
STOCH(KDJ)(9,3,3)
40.961
Neutral
ATR(14)
1.175
High Vlolatility
CCI(14)
120.696
Buy
Williams %R
49.357
Neutral
TRIX(12,20)
0.368
Sell
StochRSI(14)
100.000
Buy
Moving Average
Sell(0)
Neutral(0)
Buy(6)
Indicators
Value
Direction
MA5
15.670
Buy
MA10
15.847
Buy
MA20
15.462
Buy
MA50
14.768
Buy
MA100
13.046
Buy
MA200
13.388
Buy

Institutional Confidence

Currency: USD Updated: 2025-09-18

The company’s current institutional recognition score is 10.00, which is higher than the Biotechnology & Medical Research industry's average of 5.96. The latest institutional shareholding proportion is 91.17%, representing a quarter-over-quarter increase of 2.90%. The largest institutional shareholder is The Vanguard, holding a total of 1.82M shares, representing 4.85% of shares outstanding, with 5.44% increase in holdings.

Score

Industry at a Glance

Previous score
10.00
Change
0

Institutional Shareholding

No Data

Shareholder Activity

Name
Shares Held
Chg %
Fidelity Management & Research Company LLC
5.56M
-0.01%
VR Adviser, LLC
4.15M
--
Fairmount Funds Management LLC
3.37M
--
RTW Investments L.P.
1.95M
-5.47%
Deep Track Capital LP
1.90M
+31.29%
BlackRock Institutional Trust Company, N.A.
729.14K
-0.72%
The Vanguard Group, Inc.
Star Investors
1.64M
+1.66%
Braidwell LP
1.57M
+37.01%
Commodore Capital LP
1.42M
--
Klein (Lawrence Otto)
1.10M
+29.17%
1
2

Risk Assessment

Currency: USD Updated: 2025-09-18

The company’s current risk assessment score is 3.04, which is lower than the Biotechnology & Medical Research industry's average of 3.33. The company's beta value is -0.33. This indicates that the stock tends to underperform the index during upward trending markets but experiences smaller declines during downward trending markets.

Score

Industry at a Glance

Previous score
3.04
Change
0
Beta vs S&P 500 index
-0.32
VaR
+5.16%
240-Day Maximum Drawdown
+77.76%
240-Day Volatility
+94.25%
Return
Best Daily Return
60 days
+9.89%
120 days
+13.76%
5 years
+147.64%
Worst Daily Return
60 days
-8.45%
120 days
-17.92%
5 years
-17.92%
Sharpe Ratio
60 days
+2.94
120 days
+1.41
5 years
+0.36
Risk Assessment
Maximum Drawdown
240 days
+77.76%
3 years
+77.76%
5 years
+80.18%
Return-to-Drawdown Ratio
240 days
-0.43
3 years
+0.09
5 years
-0.09
Skewness
240 days
-0.54
3 years
+13.46
5 years
+15.04
Volatility
Realised Volatility
240 days
+94.25%
5 years
+75.09%
Standardised True Range
240 days
+7.65%
5 years
+5.84%
Downside Risk-Adjusted Return
120 days
+204.64%
240 days
+204.64%
Maximum Daily Upside Volatility
60 days
+65.42%
Maximum Daily Downside Volatility
60 days
+40.89%
Liquidity
Average Turnover Rate
60 days
+0.58%
120 days
+0.62%
5 years
--
Turnover Deviation
20 days
-97.93%
60 days
-96.92%
120 days
-96.71%

Peer Comparison

Biotechnology & Medical Research
Oruka Therapeutics Inc
Oruka Therapeutics Inc
ORKA
6.50 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Krystal Biotech Inc
Krystal Biotech Inc
KRYS
8.18 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Alkermes Plc
Alkermes Plc
ALKS
7.88 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
ACADIA Pharmaceuticals Inc
ACADIA Pharmaceuticals Inc
ACAD
7.70 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Zymeworks Inc
Zymeworks Inc
ZYME
7.68 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
MiMedx Group Inc
MiMedx Group Inc
MDXG
7.66 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
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