OPKO Health Inc
OPK1.300USD
-0.010-0.76%
Close 12/24, 13:00（ET）Quotes delayed by 15 min
999.31MMarket Cap
LossP/E TTM
More Details of OPKO Health Inc Company
OPKO Health, Inc. is a multinational biopharmaceutical and diagnostics company. The Company’s segments include pharmaceutical and diagnostics. The pharmaceutical segment consists of the pharmaceutical operations it operates in Chile, Mexico, Ireland, Israel, Spain, Ecuador, France, the United States, and its global pharmaceutical research and development operations. The diagnostics segment primarily consists of clinical laboratory operations through BioReference and its point-of-care operations. Its pharmaceutical business features Somatrogon (hGH-CTP), a once-weekly human growth hormone injection, and it is marketed under the brand name NGENLA. The Company, through its pharmaceutical division, manufactures and sells Rayaldee, a United States Food and Drug Administration (FDA) approved treatment for secondary hyperparathyroidism (SHPT) in adults with stage 3 or 4 chronic kidney disease (CKD) and vitamin D insufficiency.
OPKO Health Inc Info
Ticker SymbolOPK
Company nameOPKO Health Inc
IPO dateNov 02, 1995
CEOCruz (Tony F)
Number of employees2997
Security typeOrdinary Share
Fiscal year-endNov 02
Address- -
City- -
Stock exchangeNASDAQ OMX - NASDAQ BASIC
Country- -
Postal code- -
Phone- -
Website- -
Ticker SymbolOPK
IPO dateNov 02, 1995
CEOCruz (Tony F)
Company Executives of OPKO Health Inc
Name
Name/Position
Position
Shareholding
Change
Dr. Jane H. Hsiao, Ph.D.
Dr. Jane H. Hsiao, Ph.D.
Vice Chairman of the Board, Chief Technical Officer
Vice Chairman of the Board, Chief Technical Officer
33.13M
--
Mr. Steven D. (Steve) Rubin, Esq., J.D.
Mr. Steven D. (Steve) Rubin, Esq., J.D.
Executive Vice President - Administration, Director
Executive Vice President - Administration, Director
6.19M
-6.60%
Mr. John A. Paganelli
Mr. John A. Paganelli
Independent Director
Independent Director
393.51K
--
Mr. Adam E. Logal
Mr. Adam E. Logal
Chief Financial Officer, Senior Vice President, Chief Accounting Officer, Treasurer
Chief Financial Officer, Senior Vice President, Chief Accounting Officer, Treasurer
179.16K
-70.95%
Dr. Richard M. Krasno, Ph.D.
Dr. Richard M. Krasno, Ph.D.
Independent Director
Independent Director
103.33K
--
Dr. Elias A. Zerhouni, M.D.
Dr. Elias A. Zerhouni, M.D.
President, Vice Chairman of the Board
President, Vice Chairman of the Board
89.60K
-84.80%
Dr. Alice Lin-Tsing Yu, M.D., Ph.D.
Dr. Alice Lin-Tsing Yu, M.D., Ph.D.
Independent Director
Independent Director
66.49K
--
Mr. Richard C. (Rick) Pfenniger, Jr.
Mr. Richard C. (Rick) Pfenniger, Jr.
Independent Director
Independent Director
--
--
Dr. Tony F. Cruz, Ph.D.
Dr. Tony F. Cruz, Ph.D.
Chief Executive Officer, Transition Therapeutics, Inc
Chief Executive Officer, Transition Therapeutics, Inc
--
--
Dr. Roger J. Medel, M.D.
Dr. Roger J. Medel, M.D.
Independent Director
Independent Director
--
--
View more
Name
Name/Position
Position
Shareholding
Change
Dr. Jane H. Hsiao, Ph.D.
Dr. Jane H. Hsiao, Ph.D.
Vice Chairman of the Board, Chief Technical Officer
Vice Chairman of the Board, Chief Technical Officer
33.13M
--
Mr. Steven D. (Steve) Rubin, Esq., J.D.
Mr. Steven D. (Steve) Rubin, Esq., J.D.
Executive Vice President - Administration, Director
Executive Vice President - Administration, Director
6.19M
-6.60%
Mr. John A. Paganelli
Mr. John A. Paganelli
Independent Director
Independent Director
393.51K
--
Mr. Adam E. Logal
Mr. Adam E. Logal
Chief Financial Officer, Senior Vice President, Chief Accounting Officer, Treasurer
Chief Financial Officer, Senior Vice President, Chief Accounting Officer, Treasurer
179.16K
-70.95%
Dr. Richard M. Krasno, Ph.D.
Dr. Richard M. Krasno, Ph.D.
Independent Director
Independent Director
103.33K
--
Dr. Elias A. Zerhouni, M.D.
Dr. Elias A. Zerhouni, M.D.
President, Vice Chairman of the Board
President, Vice Chairman of the Board
89.60K
-84.80%
Revenue Breakdown
Currency: USDUpdated: Mon, Oct 6
Currency: USDUpdated: Mon, Oct 6
FY2025Q2
FY2025Q1
FY2024
FY2024Q4
FY2024Q3
FY2024Q2
FY2024Q1
FY2023
FY2023Q4
FY2023Q3
FY2023Q2
FY2023Q1
FY2022
FY2022Q4
FY2022Q3
FY2022Q2
FY2021
FY2020
FY2019
By BusinessUSD
Name
Revenue
Proportion
Health Insurers
58.48M
57.84%
Client Payers
23.17M
22.92%
Government Payers
17.10M
16.92%
Patients
2.35M
2.33%
By RegionUSD
Name
Revenue
Proportion
United States
114.88M
73.26%
Chile
16.00M
15.83%
Ireland
11.74M
11.61%
Spain
6.72M
6.65%
Mexico
6.30M
6.23%
Other
-54.55M
-13.59%
By Business
By Region
By BusinessUSD
Name
Revenue
Proportion
Health Insurers
58.48M
57.84%
Client Payers
23.17M
22.92%
Government Payers
17.10M
16.92%
Patients
2.35M
2.33%
Shareholding Stats
Updated: Sun, Nov 16
Updated: Sun, Nov 16
Shareholders
Shareholder Types
Shareholders
Shareholders
Proportion
Frost Gamma Investments Trust
28.98%
Rubric Capital Management LP
6.23%
Holbrook (Bruce C)
5.26%
The Vanguard Group, Inc.
4.88%
Hsiao (Jane H)
4.32%
Other
50.34%
Shareholders
Shareholders
Proportion
Frost Gamma Investments Trust
28.98%
Rubric Capital Management LP
6.23%
Holbrook (Bruce C)
5.26%
The Vanguard Group, Inc.
4.88%
Hsiao (Jane H)
4.32%
Other
50.34%
Shareholder Types
Shareholders
Proportion
Corporation
38.14%
Investment Advisor
12.40%
Individual Investor
10.57%
Hedge Fund
7.37%
Investment Advisor/Hedge Fund
5.49%
Research Firm
0.48%
Bank and Trust
0.21%
Pension Fund
0.14%
Family Office
0.05%
Other
25.15%
Institutional Shareholding
Updated: Wed, Oct 1
Updated: Wed, Oct 1
Reporting Period
No. of institutions
Shares Held
Proportion
Change
2025Q3
457
208.31M
27.13%
-63.18M
2025Q2
472
618.23M
77.88%
-578.48K
2025Q1
498
645.32M
88.41%
+25.74M
2024Q4
501
573.04M
84.80%
-7.63M
2024Q3
497
562.18M
81.01%
-12.00M
2024Q2
501
553.77M
79.70%
+8.59M
2024Q1
492
531.83M
76.52%
-21.84M
2023Q4
493
533.01M
69.65%
+31.42M
2023Q3
496
529.79M
69.24%
+23.70M
2023Q2
502
536.53M
70.13%
+25.42M
View more
Shareholder Activity
Name
Shares Held
Proportion
Change
Chg %
Date
Frost Gamma Investments Trust
220.16M
27.74%
+360.00K
+0.16%
Sep 30, 2025
Rubric Capital Management LP
47.79M
6.02%
-915.40K
-1.88%
Jun 30, 2025
Holbrook (Bruce C)
40.38M
5.09%
--
--
Feb 24, 2025
The Vanguard Group, Inc.
38.16M
4.81%
+8.74M
+29.70%
Jun 30, 2025
Hsiao (Jane H)
33.13M
4.17%
--
--
Apr 02, 2025
Frost Group, L.L.C.
30.13M
3.8%
--
--
Sep 30, 2025
BlackRock Institutional Trust Company, N.A.
28.22M
3.55%
+3.45M
+13.93%
Jun 30, 2025
GJN 2021 Trust
19.91M
2.51%
--
--
Feb 24, 2025
EGN 2021 Trust
19.91M
2.51%
--
--
Feb 24, 2025
Geode Capital Management, L.L.C.
10.42M
1.31%
+2.00M
+23.68%
Jun 30, 2025
View more
Related ETFs
Updated: Tue, Dec 2
Updated: Tue, Dec 2
Name
Proportion
Invesco NASDAQ Future Gen 200 ETF
0.53%
State Street SPDR S&P Health Care Services ETF
0.46%
VanEck Israel ETF
0.14%
Humankind US Stock ETF
0.1%
iShares U.S. Healthcare Providers ETF
0.1%
Goldman Sachs Innovate Equity ETF
0.06%
iShares MSCI USA Small-Cap Min Vol Factor ETF
0.05%
iShares Russell 2000 Value ETF
0.04%
iShares Biotechnology ETF
0.04%
Invesco RAFI US 1500 Small-Mid ETF
0.04%
View more
Invesco NASDAQ Future Gen 200 ETF
Proportion0.53%
State Street SPDR S&P Health Care Services ETF
Proportion0.46%
VanEck Israel ETF
Proportion0.14%
Humankind US Stock ETF
Proportion0.1%
iShares U.S. Healthcare Providers ETF
Proportion0.1%
Goldman Sachs Innovate Equity ETF
Proportion0.06%
iShares MSCI USA Small-Cap Min Vol Factor ETF
Proportion0.05%
iShares Russell 2000 Value ETF
Proportion0.04%
iShares Biotechnology ETF
Proportion0.04%
Invesco RAFI US 1500 Small-Mid ETF
Proportion0.04%
Dividend
A total of
0.00
USD has been distributed in dividends over the past 5 years.
Date
Dividend
Record Date
Payment Date
Ex-dividend Date
No Data
Stock Split
Date
Type
Ratio
No Data
Date
Type
Ratio
No Data
FAQs
Who are the top five shareholders of OPKO Health Inc?
The top five shareholders of OPKO Health Inc are:
Frost Gamma Investments Trust holds 220.16M shares, accounting for 27.74% of the total shares.
Rubric Capital Management LP holds 47.79M shares, accounting for 6.02% of the total shares.
Holbrook (Bruce C) holds 40.38M shares, accounting for 5.09% of the total shares.
The Vanguard Group, Inc. holds 38.16M shares, accounting for 4.81% of the total shares.
Hsiao (Jane H) holds 33.13M shares, accounting for 4.17% of the total shares.
Frost Gamma Investments Trust holds 220.16M shares, accounting for 27.74% of the total shares.
Rubric Capital Management LP holds 47.79M shares, accounting for 6.02% of the total shares.
Holbrook (Bruce C) holds 40.38M shares, accounting for 5.09% of the total shares.
The Vanguard Group, Inc. holds 38.16M shares, accounting for 4.81% of the total shares.
Hsiao (Jane H) holds 33.13M shares, accounting for 4.17% of the total shares.
What are the top three shareholder types of OPKO Health Inc?
The top three shareholder types of OPKO Health Inc are:
Frost Gamma Investments Trust
Rubric Capital Management LP
Holbrook (Bruce C)
Frost Gamma Investments Trust
Rubric Capital Management LP
Holbrook (Bruce C)
How many institutions hold shares of OPKO Health Inc (OPK)?
As of 2025Q3, 457 institutions hold shares of OPKO Health Inc, with a combined market value of approximately 208.31M, accounting for 27.13% of the total shares. Compared to 2025Q2, institutional shareholding has increased by -50.75%.
What is the biggest source of revenue for OPKO Health Inc?
In FY2025Q2, the Health Insurers business generated the highest revenue for OPKO Health Inc, amounting to 58.48M and accounting for 57.84% of total revenue.
