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NuCana PLC

NCNA
3.630USD
-0.310-7.87%
Close 11/04, 16:00ETQuotes delayed by 15 min
124.64KMarket Cap
LossP/E TTM

NuCana PLC

3.630
-0.310-7.87%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of NuCana PLC

Currency: USD Updated: 2025-10-27

Key Insights

Its valuation is considered fairly valued,and institutional recognition is low. Over the past 30 days, multiple analysts have rated the company as a . The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

NuCana PLC's Score

Industry at a Glance

Industry Ranking
304 / 501
Overall Ranking
582 / 4682
Industry
Biotechnology & Medical Research

Support & Resistance

No Data

Score Analysis

Current score
Previous score

Analyst Rating

Based on 0 analysts
--
Current Rating
25.000
Target Price
+2764.34%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

NuCana PLC Highlights

StrengthsRisks
NuCana plc is a United Kingdom-based clinical-stage biopharmaceutical company. The Company is focused on developing treatment outcomes for patients with cancer by applying its ProTide technology. The Company's pipeline includes NUC-3373, and NUC-7738. NUC-3373 is a ProTide transformation of the active anti-cancer metabolite of 5-fluorouracil (5-FU). 5-FU is a prescribed anti-cancer agent. NUC-3373 has been evaluated in a Phase I clinical trial for patients with advanced solid tumors and is under Phase Ib/II clinical trial for patients with advanced colorectal cancer. NUC-7738 is a ProTide transformation of a nucleoside analog, 3’-deoxyadenosine (3’-Da). The Company is evaluating NUC-7738 in a Phase I/II clinical trial for patients with advanced solid tumors. Its pipeline also includes Acelari, which is a ProTide transformation of the nucleoside analog gemcitabine. The Company’s subsidiaries include NuCana, Inc., NuCana Limited and NuCana BioMed Trustee Company Limited.
Fairly Valued
The company’s latest PE is -0.12, at a medium 3-year percentile range.
Institutional Buying
The latest institutional holdings are 4.62K shares, increasing 29.61% quarter-over-quarter.
Held by Baillie Gifford
Star Investor Baillie Gifford holds 0.00 shares of this stock.
Lower Market Activity
The company has less investor interest, with a 20-day turnover ratio of -0.33.

Financial Health

Currency: USD Updated: 2025-10-27

There is no financial score for this company; the Biotechnology & Medical Research industry's average is 6.92.

Score

Industry at a Glance

Previous score
0.00
Change
0

Financials

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
No Data

Quality of Earnings

Operational Efficiency

Growth Potential

Shareholder Returns

NuCana PLC's Company Valuation

Currency: USD Updated: 2025-10-27

The company’s current valuation score is 7.00, which is higher than the Biotechnology & Medical Research industry's average of 6.98. Its current P/E ratio is -0.12, which is -180.70% below the recent high of 0.10 and -57719.71% above the recent low of -68.92.

Score

Industry at a Glance

Previous score
7.00
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 304/501
No Data

Earnings Forecast

Currency: USD Updated: 2025-10-27

There is no earnings forecast score for this company; the Biotechnology & Medical Research industry's average is 8.04. The average price target for NuCana PLC is 25.00, with a high of 25.00 and a low of 25.00.

Score

Industry at a Glance

Previous score
0.00
Change
0

Support & Resistance

No Data
No Data

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
No Data

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2025-10-27

The company’s current price momentum score is 5.84, which is lower than the Biotechnology & Medical Research industry's average of 6.80. Sideways: Currently, the stock price is trading between the resistance level at 6.43 and the support level at 3.00, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
5.97
Change
-0.13

Support & Resistance

No Data

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(3)
Neutral(2)
Buy(0)
Indicators
Value
Direction
MACD(12,26,9)
-0.334
Sell
RSI(14)
40.144
Neutral
STOCH(KDJ)(9,3,3)
13.296
Oversold
ATR(14)
0.372
Low Volatility
CCI(14)
-99.839
Neutral
Williams %R
99.020
Oversold
TRIX(12,20)
-0.655
Sell
StochRSI(14)
2.991
Sell
Moving Average
Sell(4)
Neutral(0)
Buy(2)
Indicators
Value
Direction
MA5
3.848
Sell
MA10
4.023
Sell
MA20
4.689
Sell
MA50
4.209
Sell
MA100
2.552
Buy
MA200
1.610
Buy

Institutional Confidence

Currency: USD Updated: 2025-10-27

The company’s current institutional recognition score is 3.00, which is lower than the Biotechnology & Medical Research industry's average of 5.11. The latest institutional shareholding proportion is 0.24%, representing a quarter-over-quarter increase of 66.37%. The largest institutional shareholder is Baillie Gifford, holding a total of 0.00 shares, representing 0.00% of shares outstanding, with 100.00% decrease in holdings.

Score

Industry at a Glance

Previous score
3.00
Change
0

Institutional Shareholding

No Data

Shareholder Activity

Name
Shares Held
Chg %
Glass Jacobson Wealth Advisors
75.00
--
Scientech Research LLC
1.27K
--
Sofinnova Investments, Inc
998.00
--
Abingworth Management Limited
667.00
--
Baader Bank AG
495.00
+890.00%
Cetera Investment Advisers LLC
412.00
--
Qube Research & Technologies Ltd
357.00
--
LPL Financial LLC
100.00
--
Jump Financial, LLC
84.00
--
1
2

Risk Assessment

Currency: USD Updated: 2025-10-27

There is no risk assessment score for the company; the Biotechnology & Medical Research industry's average is 3.49. The company's beta value is 1.52. This indicates that the stock tends to outperform the index during upward trending markets but experiences larger declines during downward trending markets.

Score

Industry at a Glance

Previous score
0.00
Change
0
Beta vs S&P 500 index
1.62
VaR
+10.43%
240-Day Maximum Drawdown
+97.76%
240-Day Volatility
+570.60%

Return

Best Daily Return
60 days
+13781.99%
120 days
+13781.99%
5 years
+13781.99%
Worst Daily Return
60 days
-15.81%
120 days
-33.18%
5 years
-65.83%
Sharpe Ratio
60 days
+2.03
120 days
+1.45
5 years
+0.45

Risk Assessment

Maximum Drawdown
240 days
+97.76%
3 years
+99.92%
5 years
+99.98%
Return-to-Drawdown Ratio
240 days
+1.56
3 years
-0.26
5 years
-0.20
Skewness
240 days
+15.52
3 years
+26.82
5 years
+34.61

Volatility

Realised Volatility
240 days
+570.60%
5 years
+288.01%
Standardised True Range
240 days
+5.59%
5 years
+65.24%
Downside Risk-Adjusted Return
120 days
+29008.28%
240 days
+29008.28%
Maximum Daily Upside Volatility
60 days
+137.21%
Maximum Daily Downside Volatility
60 days
+81.97%

Liquidity

Average Turnover Rate
60 days
+163.87%
120 days
+100.64%
5 years
--
Turnover Deviation
20 days
-33.25%
60 days
+286.73%
120 days
+137.51%

Peer Comparison

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NuCana PLC
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Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
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8.57 /10
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8.47 /10
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