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MeiraGTx Holdings PLC

MGTX
7.970USD
-0.300-3.63%
Close 12/26, 16:00ETQuotes delayed by 15 min
641.42MMarket Cap
LossP/E TTM

MeiraGTx Holdings PLC

7.970
-0.300-3.63%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of MeiraGTx Holdings PLC

Currency: USD Updated: 2025-12-26

Key Insights

MeiraGTx Holdings PLC's fundamentals are relatively weak, and its growth potential is significant.Its valuation is considered fairly valued, ranking 143/404 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Buy, with the highest price target at 27.50.In the medium term, the stock price is expected to remain stable.Despite an average stock market performance over the past month, the company shows strong technicals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

MeiraGTx Holdings PLC's Score

Industry at a Glance

Industry Ranking
143 / 404
Overall Ranking
267 / 4563
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Analyst Rating

Based on 8 analysts
Buy
Current Rating
27.500
Target Price
+217.55%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

MeiraGTx Holdings PLC Highlights

StrengthsRisks
MeiraGTx Holdings PLC is a vertically integrated, clinical-stage genetic medicines company. It has a pipeline of late-stage clinical programs, including Parkinson’s disease, radiation-induced xerostomia and AIPL1-associated retinal dystrophy. It is focused on vivo delivery of vectorized biologic therapeutics addressing unmet needs in prevalent disorders, including severe forms of xerostomia, neurodegenerative diseases and ocular diseases, including inherited retinal diseases (IRDs), and large degenerative ocular diseases. The Company’s product pipeline includes Botaretigene Sparoparvovec for the treatment of X-linked Retinitis Pigmentosa; AAV-hAQP1 for the treatment of Radiation-Induced Grade 2/3 Xerostomia; AAV-hAQP1 for the treatment of Sjogren’s Syndrome; AAV-GAD for the treatment of Parkinson’s Disease; AAV-RPE65 for the treatment of RPE65-Associated Retinal Dystrophy; AAV-CNGB3 and AAV-CNGA3 for the treatment of Achromatopsia; AAV-AIPL1 for the treatment of LCA4, and others.
High Growth
The company's revenue has grown steadily over the past 3 years, averaging 109.04% year-on-year.
Growing
The company is in a growing phase, with the latest annual income totaling USD 33.28M.
Fairly Valued
The company’s latest PE is -3.79, at a medium 3-year percentile range.
Institutional Buying
The latest institutional holdings are 52.30M shares, increasing 4.57% quarter-over-quarter.
Held by PRFDX
Star Investor PRFDX holds 4.26K shares of this stock.
Lower Market Activity
The company has less investor interest, with a 20-day turnover ratio of -0.18.

Financial Health

Currency: USD Updated: 2025-12-26

The current financial score of MeiraGTx Holdings PLC is 5.03, ranking 394/404 in the Biotechnology & Medical Research industry. Its financial status is weak, and its operating efficiency is low. Its latest quarterly revenue reached 410.00K, representing a year-over-year decrease of 96.24%, while its net profit experienced a year-over-year decrease of 28.43%.

Score

Industry at a Glance

Previous score
5.03
Change
0

Financials

3.68

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

6.73

Operational Efficiency

2.83

Growth Potential

4.83

Shareholder Returns

7.07

MeiraGTx Holdings PLC's Company Valuation

Currency: USD Updated: 2025-12-26

The current valuation score of MeiraGTx Holdings PLC is 5.92, ranking 366/404 in the Biotechnology & Medical Research industry. Its current P/E ratio is -3.79, which is -61.79% below the recent high of -1.45 and -56.03% above the recent low of -5.91.

Score

Industry at a Glance

Previous score
5.92
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 143/404
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2025-12-26

The current earnings forecast score of MeiraGTx Holdings PLC is 8.50, ranking 105/404 in the Biotechnology & Medical Research industry. The average price target for MeiraGTx Holdings PLC is 27.00, with a high of 50.00 and a low of 15.00.

Score

Industry at a Glance

Previous score
8.50
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 8 analysts
Buy
Current Rating
27.500
Target Price
+217.55%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

534
Total
6
Median
6
Average
Company name
Ratings
Analysts
MeiraGTx Holdings PLC
MGTX
8
CRISPR Therapeutics AG
CRSP
30
argenx SE
ARGX
25
Intellia Therapeutics Inc
NTLA
25
IQVIA Holdings Inc
IQV
25
Ionis Pharmaceuticals Inc
IONS
24
1
2
3
...
107

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2025-12-26

The current price momentum score of MeiraGTx Holdings PLC is 6.77, ranking 199/404 in the Biotechnology & Medical Research industry. Currently, the stock price is trading between the resistance level at 9.11 and the support level at 7.21, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
7.17
Change
-0.4

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(2)
Neutral(3)
Buy(0)
Indicators
Value
Direction
MACD(12,26,9)
-0.100
Neutral
RSI(14)
45.564
Neutral
STOCH(KDJ)(9,3,3)
17.084
Oversold
ATR(14)
0.548
High Vlolatility
CCI(14)
-83.684
Neutral
Williams %R
88.439
Oversold
TRIX(12,20)
0.023
Sell
StochRSI(14)
35.212
Sell
Moving Average
Sell(5)
Neutral(0)
Buy(1)
Indicators
Value
Direction
MA5
8.088
Sell
MA10
8.293
Sell
MA20
8.320
Sell
MA50
8.352
Sell
MA100
8.115
Sell
MA200
7.396
Buy

Institutional Confidence

Currency: USD Updated: 2025-12-26

The current institutional shareholding score of MeiraGTx Holdings PLC is 5.00, ranking 146/404 in the Biotechnology & Medical Research industry. The latest institutional shareholding proportion is 65.02%, representing a quarter-over-quarter decrease of 22.84%. The largest institutional shareholder is The Vanguard, holding a total of 463.94K shares, representing 0.58% of shares outstanding, with 1.82% increase in holdings.

Score

Industry at a Glance

Previous score
5.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
Perceptive Advisors LLC
12.63M
+0.36%
Sanofi SA
12.20M
--
Johnson & Johnson Innovation-JJDC, Inc.
6.64M
--
Adage Capital Management, L.P.
6.03M
+7.10%
Prosight Capital
4.59M
+24.27%
Rubric Capital Management LP
3.73M
+109.78%
683 Capital Management LLC
2.69M
+4.47%
Millennium Management LLC
785.18K
--
BlackRock Institutional Trust Company, N.A.
2.48M
-8.91%
J. Goldman & Co., L.P.
2.04M
+76.44%
1
2

Risk Assessment

Currency: USD Updated: 2025-12-26

The current risk assessment score of MeiraGTx Holdings PLC is 4.56, ranking 85/404 in the Biotechnology & Medical Research industry. The company's beta value is 1.38. This indicates that the stock tends to outperform the index during upward trending markets but experiences larger declines during downward trending markets.

Score

Industry at a Glance

Previous score
4.56
Change
0
Beta vs S&P 500 index
1.38
VaR
+5.77%
240-Day Maximum Drawdown
+43.82%
240-Day Volatility
+77.29%

Return

Best Daily Return
60 days
+12.38%
120 days
+12.38%
5 years
+32.59%
Worst Daily Return
60 days
-10.50%
120 days
-10.50%
5 years
-13.88%
Sharpe Ratio
60 days
+0.08
120 days
+0.38
5 years
+0.07

Risk Assessment

Maximum Drawdown
240 days
+43.82%
3 years
+58.14%
5 years
+84.84%
Return-to-Drawdown Ratio
240 days
+0.80
3 years
+0.00
5 years
-0.12
Skewness
240 days
+1.13
3 years
+1.27
5 years
+1.42

Volatility

Realised Volatility
240 days
+77.29%
5 years
+73.00%
Standardised True Range
240 days
+5.98%
5 years
+6.68%
Downside Risk-Adjusted Return
120 days
+65.56%
240 days
+65.56%
Maximum Daily Upside Volatility
60 days
+48.63%
Maximum Daily Downside Volatility
60 days
+40.45%

Liquidity

Average Turnover Rate
60 days
+0.61%
120 days
+0.75%
5 years
--
Turnover Deviation
20 days
-17.66%
60 days
+25.71%
120 days
+53.68%

Peer Comparison

Biotechnology & Medical Research
MeiraGTx Holdings PLC
MeiraGTx Holdings PLC
MGTX
6.16 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Amicus Therapeutics Inc
Amicus Therapeutics Inc
FOLD
8.82 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
IQVIA Holdings Inc
IQVIA Holdings Inc
IQV
8.69 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Dynavax Technologies Corp
Dynavax Technologies Corp
DVAX
8.65 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Krystal Biotech Inc
Krystal Biotech Inc
KRYS
8.47 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Charles River Laboratories International Inc
Charles River Laboratories International Inc
CRL
8.44 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
View more

FAQs

How does TradingKey generate the Stock Score of MeiraGTx Holdings PLC?

The TradingKey Stock Score provides a comprehensive assessment of MeiraGTx Holdings PLC based on 34 indicators derived from over 100 underlying data points.
These indicators are categorised into six key dimensions: financial health, company profile, earnings forecasts, price momentum, institutional confidence, and risk assessment, collectively providing investors with a thorough analysis of MeiraGTx Holdings PLC’s performance and outlook.

How do we generate the financial health score of MeiraGTx Holdings PLC?

To generate the financial health score of MeiraGTx Holdings PLC, we analyse various key financial indicators across several core dimensions, including financial fundamentals, earnings quality, operational efficiency, growth potential, and shareholder returns.
By integrating these comprehensive data, the financial health score not only reflects MeiraGTx Holdings PLC's overall stability, operational efficiency, and growth potential but also captures the investment returns delivered to shareholders. This score aims to support rational decision-making for investors and other stakeholders. A higher score indicates a better financial health of MeiraGTx Holdings PLC.

How do we generate the company valuation score of MeiraGTx Holdings PLC?

To generate the company valuation score of MeiraGTx Holdings PLC, we use several key financial ratios, including P/E, P/B, P/S, and P/CF. These metrics compare MeiraGTx Holdings PLC’s market value to its earnings, assets, sales, and cash flow, serving as core indicators for assessing company value.
By analysing these ratios in an all-round manner, the valuation score reflects not only the market’s current perception of MeiraGTx Holdings PLC’s value but also its future profitability and growth potential, thereby supporting more informed investment decisions. A higher score indicates a fairer valuation of MeiraGTx Holdings PLC.

How do we generate the earnings forecast score of MeiraGTx Holdings PLC?

To calculate the earnings forecast score of MeiraGTx Holdings PLC, we consider various key indicators such as analyst ratings, financial forecasts, support and resistance levels, and peer comparisons:
Current ratings and price targets directly reflect analysts’ expectations, while the upside space indicates their views on the stock’s growth potential.
Financial metrics like earnings per share (EPS), revenue, net income, and earnings before interest and taxes (EBIT) are core measures for assessing profitability.
By analysing the high, median, and low ranges of the target price, we can identify price trends and determine key support and resistance levels.
Comparing these indicators against peers provides context for the stock’s performance and helps anchor more realistic expectations.
These factors together form a comprehensive earnings forecast score that accurately reflects the stock’s expected financial performance and growth potential. A higher score suggests that analysts have a more optimistic outlook on MeiraGTx Holdings PLC’s future.

How do we generate the price momentum score of MeiraGTx Holdings PLC?

When generating the price momentum score for MeiraGTx Holdings PLC, we examine momentum indicators including support and resistance levels as well as volume metrics.
Support levels represent price points where buying interest is strong enough to prevent further declines, while resistance levels indicate prices where selling pressure may hinder upward movement. By analysing typical price volume alongside total volume, we assess overall market activity and liquidity. These indicators help identify price trends and potential shifts, enabling more accurate predictions of future earnings.
This comprehensive approach can reflect market sentiment and enable rational forecasts of MeiraGTx Holdings PLC’s prices. A higher score indicates a more stable short-term price trend for MeiraGTx Holdings PLC.

How do we generate the institutional confidence score of MeiraGTx Holdings PLC?

To generate the institutional confidence score of MeiraGTx Holdings PLC, we analyse both the proportion of shares held by institutions and the number of shares they own. A higher institutional ownership percentage indicates strong confidence of professional investors, which is generally a positive signal about MeiraGTx Holdings PLC’s potential. By examining the number of shares held, we gain deeper insight into institutions’ commitment and attitude toward the stock, as institutional investors typically conduct thorough analysis before making investment decisions. Understanding institutional confidence helps us refine earnings forecasts and provides a more reliable perspective on the company’s future performance and market stability. A higher score indicates greater institutional endorsement of MeiraGTx Holdings PLC.

How do we generate the risk management score of MeiraGTx Holdings PLC?

To assess the risk management score of MeiraGTx Holdings PLC, we examine multiple key indicators related to returns, risk, volatility, and liquidity.
The highest and lowest daily returns reflect the potential size of gains and losses, while the Sharpe ratio measures risk-adjusted return performance. On the risk side, we analyse maximum drawdown and the return-to-drawdown ratio to identify extreme loss scenarios. Skewness helps assess the distribution of returns and whether performance may be biased. Volatility indicators—such as realised volatility and standardised true range—reveal price fluctuations. Downside risk-adjusted returns provide insight into potential losses and gains. Lastly, liquidity metrics like average turnover rate and turnover deviation indicate how actively the stock is traded.
These indicators together provide a multi-dimensional understanding of MeiraGTx Holdings PLC’s risk-return profile, serving as core factors of the risk management score. A higher score indicates lower risk on the side of MeiraGTx Holdings PLC.
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