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Madrigal Pharmaceuticals Inc

MDGL
495.910USD
-3.260-0.65%
Close 01/27, 16:00ETQuotes delayed by 15 min
11.26BMarket Cap
LossP/E TTM

Madrigal Pharmaceuticals Inc

495.910
-3.260-0.65%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Madrigal Pharmaceuticals Inc

Currency: USD Updated: 2026-01-26

Key Insights

Madrigal Pharmaceuticals Inc's fundamentals are relatively healthy, and its growth potential is high.Its valuation is considered fairly valued, ranking 22 out of 394 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Buy, with the highest price target at 628.40.In the medium term, the stock price is expected to trend up.Despite a very weak market performance over the past month, the company shows strong fundamentals and technicals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Madrigal Pharmaceuticals Inc's Score

Industry at a Glance

Industry Ranking
22 / 394
Overall Ranking
98 / 4542
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Media Coverage

Last 24 hours
Coverage Level

Very Low
Very High
Neutral

Madrigal Pharmaceuticals Inc Highlights

StrengthsRisks
Madrigal Pharmaceuticals, Inc. is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a liver disease with high unmet medical need. The Company’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-b agonist designed to target key underlying causes of MASH. Rezdiffra is the medication approved by the United States Food and Drug Administration (FDA) for the treatment of MASH with moderate to advanced fibrosis (consistent with stages F2 to F3). Rezdiffra is a prescribed medicine used along with diet and exercise to treat adults with nonalcoholic steatohepatitis (NASH) with moderate to advanced liver scarring (fibrosis), but not with cirrhosis of the liver. An ongoing Phase III outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (consistent with stage F4c).
High Profit Growth
The company's net income leads the industry, with the latest annual income totaling USD 180.13M.
Undervalued
The company’s latest PE is -38.66, at a low 3-year percentile range.
Institutional Selling
The latest institutional holdings are 21.93M shares, decreasing 9.21% quarter-over-quarter.
Held by Invesco
Star Investor Invesco holds 24.48K shares of this stock.

Analyst Rating

Based on 16 analysts
Buy
Current Rating
415.786
Target Price
+25.53%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Financial Health

Currency: USD Updated: 2026-01-26

The current financial score of Madrigal Pharmaceuticals Inc is 8.16, ranking 59 out of 394 in the Biotechnology & Medical Research industry. Its financial status is stable, and its operating efficiency is high. Its latest quarterly revenue reached 287.27M, representing a year-over-year increase of 362.03%, while its net profit experienced a year-over-year increase of 6.76%.

Score

Industry at a Glance

Previous score
8.16
Change
0

Financials

6.76

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

6.40

Operational Efficiency

10.00

Growth Potential

10.00

Shareholder Returns

7.66

Madrigal Pharmaceuticals Inc's Company Valuation

Currency: USD Updated: 2026-01-26

The current valuation score of Madrigal Pharmaceuticals Inc is 7.21, ranking 153 out of 394 in the Biotechnology & Medical Research industry. Its current P/E ratio is -38.66, which is -88.57% below the recent high of -4.42 and -20.77% above the recent low of -46.69.

Score

Industry at a Glance

Previous score
7.21
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 22/394
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2026-01-26

The current earnings forecast score of Madrigal Pharmaceuticals Inc is 8.12, ranking 161 out of 394 in the Biotechnology & Medical Research industry. The average price target is 557.00, with a high of 650.00 and a low of 456.00.

Score

Industry at a Glance

Previous score
8.12
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 17 analysts
Buy
Current Rating
628.400
Target Price
+30.79%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

541
Total
6
Median
6
Average
Company name
Ratings
Analysts
Madrigal Pharmaceuticals Inc
MDGL
17
CRISPR Therapeutics AG
CRSP
30
argenx SE
ARGX
26
Intellia Therapeutics Inc
NTLA
25
IQVIA Holdings Inc
IQV
25
Beigene Ltd
ONC
24
1
2
3
...
108

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2026-01-26

The current price momentum score of Madrigal Pharmaceuticals Inc is 7.02, ranking 173 out of 394 in the Biotechnology & Medical Research industry. Currently, the stock price is trading between the resistance level at 583.01 and the support level at 440.65, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
6.78
Change
0.24

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(3)
Neutral(2)
Buy(2)
Indicators
Value
Direction
MACD(12,26,9)
-7.059
Sell
RSI(14)
39.748
Neutral
STOCH(KDJ)(9,3,3)
60.345
Buy
ATR(14)
22.112
Low Volatility
CCI(14)
-47.474
Neutral
Williams %R
72.250
Sell
TRIX(12,20)
-0.633
Sell
StochRSI(14)
100.000
Buy
Moving Average
Sell(4)
Neutral(0)
Buy(2)
Indicators
Value
Direction
MA5
495.004
Buy
MA10
497.666
Sell
MA20
530.721
Sell
MA50
554.237
Sell
MA100
498.261
Sell
MA200
408.350
Buy

Institutional Confidence

Currency: USD Updated: 2026-01-26

The current institutional shareholding score of Madrigal Pharmaceuticals Inc is 10.00, ranking 1 out of 394 in the Biotechnology & Medical Research industry. The latest institutional shareholding proportion is 96.57%, representing a quarter-over-quarter decrease of 0.25%. The largest institutional shareholder is John Paulson, holding a total of 1.91M shares, representing 8.40% of shares outstanding, with 11.67% decrease in holdings.

Score

Industry at a Glance

Previous score
10.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
Baker Bros. Advisors LP
2.14M
--
RTW Investments L.P.
1.99M
--
Paulson & Co. Inc.
Star Investors
1.91M
-8.71%
Janus Henderson Investors
1.84M
-15.93%
Avoro Capital Advisors LLC
1.83M
-2.24%
The Vanguard Group, Inc.
Star Investors
1.81M
-3.49%
BlackRock Institutional Trust Company, N.A.
1.34M
+6.62%
State Street Investment Management (US)
658.10K
-4.72%
SQN, L.L.C.
655.54K
--
Geode Capital Management, L.L.C.
446.23K
+7.68%
1
2

Risk Assessment

Currency: USD Updated: 2026-01-26

The U.S. Dollar Index is currently in a neutral state, which has a neutral effect on the Biotechnology & Medical Research domestic-focused industry. The Dollar Index (DXY) measures the value of the U.S. dollar against a basket of major currencies, including the euro, yen, pound sterling, Canadian dollar, Swedish krona, and Swiss franc. The current risk assessment score of Madrigal Pharmaceuticals Inc is 7.08, ranking 18 out of 394 in the Biotechnology & Medical Research industry. The company's beta value is -1.02. This indicates that the stock tends to underperform the index during upward trending markets but experiences smaller declines during downward trending markets.

Score

Industry at a Glance

Previous score
7.08
Change
0
Beta vs S&P 500 index
-1.02
VaR
+5.27%
240-Day Maximum Drawdown
+24.82%
240-Day Volatility
+54.48%

Return

Best Daily Return
60 days
+9.20%
120 days
+9.20%
5 years
+268.07%
Worst Daily Return
60 days
-7.58%
120 days
-7.58%
5 years
-13.32%
Sharpe Ratio
60 days
+1.37
120 days
+2.55
5 years
+0.56

Risk Assessment

Maximum Drawdown
240 days
+24.82%
3 years
+61.41%
5 years
+61.41%
Return-to-Drawdown Ratio
240 days
+1.93
3 years
+0.58
5 years
+0.96
Skewness
240 days
+1.00
3 years
+0.79
5 years
+25.53

Volatility

Realised Volatility
240 days
+54.48%
5 years
+80.78%
Standardised True Range
240 days
+3.62%
5 years
+2.23%
Downside Risk-Adjusted Return
120 days
+532.45%
240 days
+532.45%
Maximum Daily Upside Volatility
60 days
+47.97%
Maximum Daily Downside Volatility
60 days
+32.04%

Liquidity

Average Turnover Rate
60 days
+1.69%
120 days
+1.62%
5 years
--
Turnover Deviation
20 days
+0.55%
60 days
-15.52%
120 days
-19.01%

Peer Comparison

Biotechnology & Medical Research
Madrigal Pharmaceuticals Inc
Madrigal Pharmaceuticals Inc
MDGL
7.86 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
IQVIA Holdings Inc
IQVIA Holdings Inc
IQV
8.79 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Ascendis Pharma A/S
Ascendis Pharma A/S
ASND
8.65 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Alkermes Plc
Alkermes Plc
ALKS
8.55 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Krystal Biotech Inc
Krystal Biotech Inc
KRYS
8.47 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Charles River Laboratories International Inc
Charles River Laboratories International Inc
CRL
8.41 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
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