tradingkey.logo
tradingkey.logo

Madrigal Pharmaceuticals Inc

MDGL
468.425USD
+20.705+4.62%
Market hours ETQuotes delayed by 15 min
771.42MMarket Cap
LossP/E TTM

Madrigal Pharmaceuticals Inc

468.425
+20.705+4.62%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Madrigal Pharmaceuticals Inc

Currency: USD Updated: 2026-03-24

Key Insights

Madrigal Pharmaceuticals Inc's fundamentals are relatively healthy, with an industry-leading ESG disclosure.and its growth potential is high.Its valuation is considered fairly valued, ranking 4 out of 391 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Buy, with the highest price target at 659.53.In the medium term, the stock price is expected to trend down.Despite an average stock market performance over the past month, the company shows strong fundamentals and technicals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Madrigal Pharmaceuticals Inc's Score

Industry at a Glance

Industry Ranking
4 / 391
Overall Ranking
50 / 4547
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Media Coverage

Last 24 hours
Coverage Level

Very Low
Very High
Neutral

Madrigal Pharmaceuticals Inc Highlights

StrengthsRisks
Madrigal Pharmaceuticals, Inc. is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a liver disease with high unmet medical need. The Company’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-b agonist designed to target key underlying causes of MASH. Rezdiffra is the medication approved by the United States Food and Drug Administration (FDA) for the treatment of MASH with moderate to advanced fibrosis (consistent with stages F2 to F3). Rezdiffra is a prescribed medicine used along with diet and exercise to treat adults with nonalcoholic steatohepatitis (NASH) with moderate to advanced liver scarring (fibrosis), but not with cirrhosis of the liver. An ongoing Phase III outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (consistent with stage F4c).
Undervalued
The company’s latest PE is -34.63, at a low 3-year percentile range.
Institutional Selling
The latest institutional holdings are 21.87M shares, decreasing 8.28% quarter-over-quarter.
Held by Paul Tudor Jones
Star Investor Paul Tudor Jones holds 5.29K shares of this stock.

Analyst Rating

Based on 16 analysts
Buy
Current Rating
415.786
Target Price
+25.53%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Financial Health

Currency: USD Updated: 2026-03-24

The current financial score of Madrigal Pharmaceuticals Inc is 8.13, ranking 49 out of 391 in the Biotechnology & Medical Research industry. Its financial status is stable, and its operating efficiency is high. Its latest quarterly revenue reached 321.08M, representing a year-over-year increase of 210.77%, while its net profit experienced a year-over-year increase of 1.42%.

Score

Industry at a Glance

Previous score
8.13
Change
0

Financials

6.16

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

9.38

Operational Efficiency

8.30

Growth Potential

9.36

Shareholder Returns

7.46

Madrigal Pharmaceuticals Inc's Company Valuation

Currency: USD Updated: 2026-03-24

The current valuation score of Madrigal Pharmaceuticals Inc is 7.21, ranking 147 out of 391 in the Biotechnology & Medical Research industry. Its current P/E ratio is -34.63, which is -87.24% below the recent high of -4.42 and -34.81% above the recent low of -46.69.

Score

Industry at a Glance

Previous score
7.21
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 4/391
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2026-03-24

The current earnings forecast score of Madrigal Pharmaceuticals Inc is 8.12, ranking 160 out of 391 in the Biotechnology & Medical Research industry. The average price target is 557.00, with a high of 650.00 and a low of 456.00.

Score

Industry at a Glance

Previous score
8.12
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 17 analysts
Buy
Current Rating
659.533
Target Price
+49.50%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

548
Total
6
Median
6
Average
Company name
Ratings
Analysts
Madrigal Pharmaceuticals Inc
MDGL
17
CRISPR Therapeutics AG
CRSP
29
IQVIA Holdings Inc
IQV
27
argenx SE
ARGX
26
Beigene Ltd
ONC
24
Intellia Therapeutics Inc
NTLA
24
1
2
3
...
110

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2026-03-24

The current price momentum score of Madrigal Pharmaceuticals Inc is 8.77, ranking 34 out of 391 in the Biotechnology & Medical Research industry. Currently, the stock price is trading between the resistance level at 469.22 and the support level at 418.53, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
8.93
Change
-0.16

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(1)
Neutral(6)
Buy(0)
Indicators
Value
Direction
MACD(12,26,9)
7.317
Neutral
RSI(14)
47.257
Neutral
STOCH(KDJ)(9,3,3)
55.250
Neutral
ATR(14)
16.697
Low Volatility
CCI(14)
37.468
Neutral
Williams %R
45.372
Neutral
TRIX(12,20)
-0.194
Sell
StochRSI(14)
37.760
Neutral
Moving Average
Sell(1)
Neutral(0)
Buy(5)
Indicators
Value
Direction
MA5
446.028
Buy
MA10
442.924
Buy
MA20
438.826
Buy
MA50
465.023
Buy
MA100
506.208
Sell
MA200
438.990
Buy

Institutional Confidence

Currency: USD Updated: 2026-03-24

The current institutional shareholding score of Madrigal Pharmaceuticals Inc is 10.00, ranking 1 out of 391 in the Biotechnology & Medical Research industry. The latest institutional shareholding proportion is 96.31%, representing a quarter-over-quarter decrease of 0.52%. The largest institutional shareholder is The Vanguard, holding a total of 1.81M shares, representing 7.87% of shares outstanding, with 3.58% increase in holdings.

Score

Industry at a Glance

Previous score
10.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
Baker Bros. Advisors LP
2.14M
--
RTW Investments L.P.
1.99M
--
Avoro Capital Advisors LLC
1.83M
-2.24%
The Vanguard Group, Inc.
Star Investors
1.81M
-3.49%
Paulson & Co. Inc.
Star Investors
1.91M
-8.71%
Janus Henderson Investors
1.84M
-15.93%
BlackRock Institutional Trust Company, N.A.
1.34M
+6.62%
SQN, L.L.C.
655.54K
--
State Street Investment Management (US)
658.10K
-4.72%
Wellington Management Company, LLP
404.45K
+5381.16%
1
2

Risk Assessment

Currency: USD Updated: 2026-03-24

The U.S. Dollar Index is currently in a neutral state, which has a neutral effect on the Biotechnology & Medical Research domestic-focused industry. The Dollar Index (DXY) measures the value of the U.S. dollar against a basket of major currencies, including the euro, yen, pound sterling, Canadian dollar, Swedish krona, and Swiss franc. The current risk assessment score of Madrigal Pharmaceuticals Inc is 7.08, ranking 18 out of 391 in the Biotechnology & Medical Research industry. The company's beta value is -0.91. This indicates that the stock tends to underperform the index during upward trending markets but experiences smaller declines during downward trending markets. with an industry-leading ESG disclosure.

Score

Industry at a Glance

Previous score
7.08
Change
0
Beta vs S&P 500 index
-0.91
VaR
+5.27%
240-Day Maximum Drawdown
+29.36%
240-Day Volatility
+52.52%

Return

Best Daily Return
60 days
+4.87%
120 days
+9.20%
5 years
+268.07%
Worst Daily Return
60 days
-11.11%
120 days
-11.11%
5 years
-13.32%
Sharpe Ratio
60 days
-2.94
120 days
+0.24
5 years
+0.56

Risk Assessment

Maximum Drawdown
240 days
+29.36%
3 years
+59.82%
5 years
+61.41%
Return-to-Drawdown Ratio
240 days
+1.60
3 years
+0.27
5 years
+1.02
Skewness
240 days
+0.57
3 years
+0.74
5 years
+25.52

Volatility

Realised Volatility
240 days
+52.52%
5 years
+80.85%
Standardised True Range
240 days
+4.10%
5 years
+2.60%
Downside Risk-Adjusted Return
120 days
+37.27%
240 days
+37.27%
Maximum Daily Upside Volatility
60 days
+29.31%
Maximum Daily Downside Volatility
60 days
+36.14%

Liquidity

Average Turnover Rate
60 days
+1.69%
120 days
+1.62%
5 years
--
Turnover Deviation
20 days
+0.55%
60 days
-15.52%
120 days
-19.01%

Peer Comparison

Biotechnology & Medical Research
Madrigal Pharmaceuticals Inc
Madrigal Pharmaceuticals Inc
MDGL
8.20 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
BioCryst Pharmaceuticals Inc
BioCryst Pharmaceuticals Inc
BCRX
8.64 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
AnaptysBio Inc
AnaptysBio Inc
ANAB
8.34 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
IQVIA Holdings Inc
IQVIA Holdings Inc
IQV
8.31 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Centessa Pharmaceuticals PLC
Centessa Pharmaceuticals PLC
CNTA
8.14 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Tango Therapeutics Inc
Tango Therapeutics Inc
TNGX
8.11 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
View more
KeyAI