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Lyell Immunopharma Inc

LYEL
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17.920USD
-1.100-5.78%
Close 05/15, 16:00ETQuotes delayed by 15 min
418.15MMarket Cap
LossP/E TTM

Lyell Immunopharma Inc

17.920
-1.100-5.78%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Lyell Immunopharma Inc

Currency: USD Updated: 2026-05-15

Key Insights

Lyell Immunopharma Inc's fundamentals are relatively very healthy, with an industry-leading ESG disclosure.and its growth potential is high.Its valuation is considered fairly valued, ranking 85 out of 382 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Buy, with the highest price target at 42.20.In the medium term, the stock price is expected to trend down.Despite a very weak market performance over the past month, the company shows strong fundamentals and technicals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Lyell Immunopharma Inc's Score

Industry at a Glance

Industry Ranking
85 / 382
Overall Ranking
203 / 4482
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Media Coverage

Last 24 hours
Coverage Level

Very Low
Very High
Neutral

Lyell Immunopharma Inc Highlights

StrengthsRisks
Lyell Immunopharma, Inc. is a late-stage clinical company advancing a pipeline of next-generation chimeric antigen receptor (CAR) T-cell therapies for patients with hematologic malignancies and solid tumors. The Company’s product candidates include LYL314 and LYL273. Its LYL314, which is in Phase I/II clinical development, is a dual-targeting CD19/CD20 CAR T-cell product candidate designed to increase complete response rates and prolong the duration of response as compared to the approved CD19-targeted CAR T-cell therapies and is under evaluation trial for the treatment of patients with relapsed and/or refractory large B-cell lymphoma. The Company has acquired the global rights to LYL273 (formerly GCC19CART), a novel autologous guanylyl cyclase-C (GCC)-targeted CAR T-cell product candidate for the treatment of metastatic colorectal cancer (mCRC) and other GCC-expressing cancers.
Growing
The company is in a growing phase, with the latest annual income totaling USD 36.00K.
High Profit Growth
The company's net income leads the industry, with the latest annual income totaling USD 36.00K.
Fairly Valued
The company’s latest PE is -1.32, at a medium 3-year percentile range.
Institutional Buying
The latest institutional holdings are 13.43M shares, increasing 12.34% quarter-over-quarter.
Held by James Simons
Star Investor James Simons holds 39.49K shares of this stock.
Lower Market Activity
The company has less investor interest, with a 20-day turnover ratio of -0.01.

Analyst Rating

Based on 6 analysts
Buy
Current Rating
42.200
Target Price
+121.87%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Financial Health

Currency: USD Updated: 2026-05-15

The current financial score of Lyell Immunopharma Inc is 7.07, ranking 128 out of 382 in the Biotechnology & Medical Research industry. Its financial status is robust, and its operating efficiency is low. Its latest quarterly revenue reached 2.00K, representing a year-over-year decrease of 71.43%, while its net profit experienced a year-over-year decrease of 53.73%.

Score

Industry at a Glance

Previous score
7.07
Change
0

Financials

8.30

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

7.56

Operational Efficiency

3.02

Growth Potential

9.10

Shareholder Returns

7.36

Lyell Immunopharma Inc's Company Valuation

Currency: USD Updated: 2026-05-15

The current valuation score of Lyell Immunopharma Inc is 8.60, ranking 35 out of 382 in the Biotechnology & Medical Research industry. Its current P/E ratio is -1.32, which is -99.00% below the recent high of -0.01 and -305.91% above the recent low of -5.34.

Score

Industry at a Glance

Previous score
8.60
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 85/382
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2026-05-15

The current earnings forecast score of Lyell Immunopharma Inc is 7.67, ranking 277 out of 382 in the Biotechnology & Medical Research industry. The average price target is 25.00, with a high of 45.00 and a low of 12.00.

Score

Industry at a Glance

Previous score
7.00
Change
0.67

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 6 analysts
Buy
Current Rating
42.200
Target Price
+121.87%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

554
Total
5
Median
6
Average
Company name
Ratings
Analysts
Lyell Immunopharma Inc
LYEL
6
CRISPR Therapeutics AG
CRSP
27
IQVIA Holdings Inc
IQV
26
Beigene Ltd
ONC
26
argenx SE
ARGX
26
Ionis Pharmaceuticals Inc
IONS
25
1
2
3
...
111

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2026-05-15

The current price momentum score of Lyell Immunopharma Inc is 6.82, ranking 146 out of 382 in the Biotechnology & Medical Research industry. Currently, the stock price is trading between the resistance level at 22.82 and the support level at 15.22, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
6.86
Change
-0.04

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(3)
Neutral(1)
Buy(0)
Indicators
Value
Direction
MACD(12,26,9)
-0.587
Sell
RSI(14)
31.654
Neutral
STOCH(KDJ)(9,3,3)
17.109
Oversold
ATR(14)
1.382
Low Volatility
CCI(14)
-157.952
Sell
Williams %R
92.160
Oversold
TRIX(12,20)
-0.664
Sell
StochRSI(14)
0.000
Oversold
Moving Average
Sell(6)
Neutral(0)
Buy(0)
Indicators
Value
Direction
MA5
18.926
Sell
MA10
19.621
Sell
MA20
21.053
Sell
MA50
21.601
Sell
MA100
23.681
Sell
MA200
20.341
Sell

Institutional Confidence

Currency: USD Updated: 2026-05-15

The current institutional shareholding score of Lyell Immunopharma Inc is 5.00, ranking 135 out of 382 in the Biotechnology & Medical Research industry. The latest institutional shareholding proportion is 57.58%, representing a quarter-over-quarter increase of 14.49%. The largest institutional shareholder is James Simons, holding a total of 116.41K shares, representing 0.50% of shares outstanding, with 16.45% decrease in holdings.

Score

Industry at a Glance

Previous score
5.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
ARCH Venture Partners
3.25M
+17.69%
Innovative Cellular Therapeutics Holdings Ltd
1.90M
--
Gates Frontier, L.L.C.
1.04M
--
Explore Investments LLC
1.04M
--
GSK plc
1.51M
--
Foresite Capital Management, LLC
1.28M
--
MWG Management, Ltd.
1.01M
--
Milky Way Investments Group Ltd
1.01M
--
Orland Properties Ltd
754.70K
--
1
2

Risk Assessment

Currency: USD Updated: 2026-05-15

The U.S. Dollar Index is currently in a neutral state, which has a neutral effect on the Biotechnology & Medical Research domestic-focused industry. The Dollar Index (DXY) measures the value of the U.S. dollar against a basket of major currencies, including the euro, yen, pound sterling, Canadian dollar, Swedish krona, and Swiss franc. The current risk assessment score of Lyell Immunopharma Inc is 2.20, ranking 234 out of 382 in the Biotechnology & Medical Research industry. The company's beta value is -0.06. This indicates that the stock tends to underperform the index during upward trending markets but experiences smaller declines during downward trending markets. with an industry-leading ESG disclosure.

Score

Industry at a Glance

Previous score
2.20
Change
0
Beta vs S&P 500 index
-0.08
VaR
+8.67%
240-Day Maximum Drawdown
+53.58%
240-Day Volatility
+103.35%

Return

Best Daily Return
60 days
+13.54%
120 days
+18.77%
5 years
+68.59%
Worst Daily Return
60 days
-14.23%
120 days
-14.23%
5 years
-36.03%
Sharpe Ratio
60 days
-1.36
120 days
+0.51
5 years
-0.16

Risk Assessment

Maximum Drawdown
240 days
+53.58%
3 years
+88.36%
5 years
+97.83%
Return-to-Drawdown Ratio
240 days
+2.20
3 years
+1.80
5 years
+0.03
Skewness
240 days
+4.21
3 years
+1.73
5 years
+1.23

Volatility

Realised Volatility
240 days
+103.35%
5 years
+168.84%
Standardised True Range
240 days
+9.09%
5 years
+3.45%
Downside Risk-Adjusted Return
120 days
+85.45%
240 days
+85.45%
Maximum Daily Upside Volatility
60 days
+54.47%
Maximum Daily Downside Volatility
60 days
+49.86%

Liquidity

Average Turnover Rate
60 days
+0.61%
120 days
+0.65%
5 years
--
Turnover Deviation
20 days
+3.50%
60 days
+41.85%
120 days
+51.15%

Peer Comparison

Biotechnology & Medical Research
Lyell Immunopharma Inc
Lyell Immunopharma Inc
LYEL
6.68 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Krystal Biotech Inc
Krystal Biotech Inc
KRYS
8.57 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
BioCryst Pharmaceuticals Inc
BioCryst Pharmaceuticals Inc
BCRX
8.57 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Ascendis Pharma A/S
Ascendis Pharma A/S
ASND
8.48 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Exelixis Inc
Exelixis Inc
EXEL
8.44 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Alkermes Plc
Alkermes Plc
ALKS
8.44 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
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