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Lexicon Pharmaceuticals Inc

LXRX
1.515USD
-0.115-7.06%
Close 03/30, 16:00ETQuotes delayed by 15 min
104.01MMarket Cap
LossP/E TTM

Lexicon Pharmaceuticals Inc

1.515
-0.115-7.06%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Lexicon Pharmaceuticals Inc

Currency: USD Updated: 2026-03-27

Key Insights

Lexicon Pharmaceuticals Inc's fundamentals are relatively stable, with an industry-leading ESG disclosure.and its growth potential is significant.Its valuation is considered fairly valued, ranking 109 out of 391 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Buy, with the highest price target at 3.36.In the medium term, the stock price is expected to trend up.Despite a good stock market performance and strong technicals over the past month, the fundamentals don't support the current trend.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Lexicon Pharmaceuticals Inc's Score

Industry at a Glance

Industry Ranking
109 / 391
Overall Ranking
224 / 4542
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Media Coverage

Last 24 hours
Coverage Level

Very Low
Very High
Positive

Lexicon Pharmaceuticals Inc Highlights

StrengthsRisks
Lexicon Pharmaceuticals, Inc. is a biopharmaceutical company focusing on the research and development of pilavapadin, LX9851 and sotagliflozin and the commercialization of INPEFA. It is developing pilavapadin (LX9211), an orally delivered small molecule drug candidate, as a treatment for neuropathic pain. It has completed three Phase II clinical trials evaluating the safety and tolerability of pilavapadin and its effects on diabetic peripheral neuropathic pain (DPNP) and neuropathic pain. It is developing LX9851, an orally delivered small molecule drug candidate, as a treatment for obesity and associated cardiometabolic disorders and is conducting preclinical development of LX9851 in preparation for filing an investigational new drug application. It is commercializing INPEFA (sotagliflozin), an orally delivered small molecule drug, in the United States to reduce the risk of cardiovascular death, and urgent heart failure visits in adults with heart failure or type 2 diabetes mellitus.
High Growth
The company's revenue has grown steadily over the past 3 years, averaging 4036.46% year-on-year.
Growing
The company is in a growing phase, with the latest annual income totaling USD 49.80M.
Undervalued
The company’s latest PE is -11.90, at a low 3-year percentile range.
Institutional Selling
The latest institutional holdings are 263.45M shares, decreasing 12.83% quarter-over-quarter.
Held by Invesco
Star Investor Invesco holds 594.88K shares of this stock.
Lower Market Activity
The company has less investor interest, with a 20-day turnover ratio of -0.62.

Analyst Rating

Based on 5 analysts
Buy
Current Rating
3.360
Target Price
+106.13%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Financial Health

Currency: USD Updated: 2026-03-27

The current financial score of Lexicon Pharmaceuticals Inc is 5.66, ranking 339 out of 391 in the Biotechnology & Medical Research industry. Its financial status is weak, and its operating efficiency is low. Its latest quarterly revenue reached 5.49M, representing a year-over-year decrease of 79.31%, while its net profit experienced a year-over-year decrease of 54.01%.

Score

Industry at a Glance

Previous score
5.66
Change
0

Financials

5.91

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

7.88

Operational Efficiency

2.72

Growth Potential

4.69

Shareholder Returns

7.11

Lexicon Pharmaceuticals Inc's Company Valuation

Currency: USD Updated: 2026-03-27

The current valuation score of Lexicon Pharmaceuticals Inc is 5.98, ranking 340 out of 391 in the Biotechnology & Medical Research industry. Its current P/E ratio is -11.90, which is -100.00% below the recent high of 0.00 and -4.24% above the recent low of -12.40.

Score

Industry at a Glance

Previous score
5.98
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 109/391
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2026-03-27

The current earnings forecast score of Lexicon Pharmaceuticals Inc is 7.60, ranking 280 out of 391 in the Biotechnology & Medical Research industry. The average price target is 1.90, with a high of 6.00 and a low of 1.00.

Score

Industry at a Glance

Previous score
7.60
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 5 analysts
Buy
Current Rating
3.360
Target Price
+103.64%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

548
Total
6
Median
6
Average
Company name
Ratings
Analysts
Lexicon Pharmaceuticals Inc
LXRX
5
CRISPR Therapeutics AG
CRSP
29
IQVIA Holdings Inc
IQV
26
argenx SE
ARGX
26
Intellia Therapeutics Inc
NTLA
24
Beigene Ltd
ONC
24
1
2
3
...
110

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2026-03-27

The current price momentum score of Lexicon Pharmaceuticals Inc is 8.74, ranking 32 out of 391 in the Biotechnology & Medical Research industry. Currently, the stock price is trading between the resistance level at 1.82 and the support level at 1.45, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
7.37
Change
1.37

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(3)
Neutral(2)
Buy(0)
Indicators
Value
Direction
MACD(12,26,9)
-0.037
Neutral
RSI(14)
45.003
Neutral
STOCH(KDJ)(9,3,3)
29.603
Sell
ATR(14)
0.108
Low Volatility
CCI(14)
-129.603
Sell
Williams %R
93.333
Oversold
TRIX(12,20)
0.426
Sell
StochRSI(14)
0.000
Oversold
Moving Average
Sell(3)
Neutral(0)
Buy(3)
Indicators
Value
Direction
MA5
1.638
Sell
MA10
1.619
Sell
MA20
1.643
Sell
MA50
1.506
Buy
MA100
1.406
Buy
MA200
1.285
Buy

Institutional Confidence

Currency: USD Updated: 2026-03-27

The current institutional shareholding score of Lexicon Pharmaceuticals Inc is 5.00, ranking 136 out of 391 in the Biotechnology & Medical Research industry. The latest institutional shareholding proportion is 68.68%, representing a quarter-over-quarter decrease of 4.25%. The largest institutional shareholder is The Vanguard, holding a total of 9.61M shares, representing 2.27% of shares outstanding, with 14.24% decrease in holdings.

Score

Industry at a Glance

Previous score
5.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
Artal International S.C.A.
136.18M
--
Invus Public Equities Advisors, LLC
38.92M
--
Fidelity Management & Research Company LLC
38.68M
+1.42%
The Vanguard Group, Inc.
Star Investors
9.52M
+7.58%
Ulys, L.L.C.
5.45M
--
Millennium Management LLC
3.83M
+133.11%
BlackRock Institutional Trust Company, N.A.
3.17M
-0.12%
Sessa Capital
3.00M
--
Geode Capital Management, L.L.C.
2.40M
+0.85%
1
2

Risk Assessment

Currency: USD Updated: 2026-03-27

The U.S. Dollar Index is currently in a neutral state, which has a neutral effect on the Biotechnology & Medical Research domestic-focused industry. The Dollar Index (DXY) measures the value of the U.S. dollar against a basket of major currencies, including the euro, yen, pound sterling, Canadian dollar, Swedish krona, and Swiss franc. The current risk assessment score of Lexicon Pharmaceuticals Inc is 3.74, ranking 121 out of 391 in the Biotechnology & Medical Research industry. The company's beta value is 0.94. This indicates that the stock tends to underperform the index during upward trending markets but experiences smaller declines during downward trending markets. with an industry-leading ESG disclosure.

Score

Industry at a Glance

Previous score
3.74
Change
0
Beta vs S&P 500 index
0.87
VaR
+7.81%
240-Day Maximum Drawdown
+34.09%
240-Day Volatility
+88.45%

Return

Best Daily Return
60 days
+19.08%
120 days
+19.08%
5 years
+64.13%
Worst Daily Return
60 days
-19.44%
120 days
-19.44%
5 years
-58.17%
Sharpe Ratio
60 days
+1.99
120 days
+0.86
5 years
+0.28

Risk Assessment

Maximum Drawdown
240 days
+34.09%
3 years
+100.00%
5 years
+100.00%
Return-to-Drawdown Ratio
240 days
+6.52
3 years
-0.14
5 years
-0.13
Skewness
240 days
+0.33
3 years
+0.39
5 years
+0.55

Volatility

Realised Volatility
240 days
+88.45%
5 years
--
Standardised True Range
240 days
+5.66%
5 years
+9.50%
Downside Risk-Adjusted Return
120 days
+135.36%
240 days
+135.36%
Maximum Daily Upside Volatility
60 days
+79.10%
Maximum Daily Downside Volatility
60 days
+65.13%

Liquidity

Average Turnover Rate
60 days
+1.01%
120 days
+2.57%
5 years
--
Turnover Deviation
20 days
-61.77%
60 days
-37.90%
120 days
+58.18%

Peer Comparison

Biotechnology & Medical Research
Lexicon Pharmaceuticals Inc
Lexicon Pharmaceuticals Inc
LXRX
6.45 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Alkermes Plc
Alkermes Plc
ALKS
8.42 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Madrigal Pharmaceuticals Inc
Madrigal Pharmaceuticals Inc
MDGL
8.27 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
BioCryst Pharmaceuticals Inc
BioCryst Pharmaceuticals Inc
BCRX
8.27 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Day One Biopharmaceuticals Inc
Day One Biopharmaceuticals Inc
DAWN
8.26 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
IQVIA Holdings Inc
IQVIA Holdings Inc
IQV
8.21 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
View more
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