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Iovance Biotherapeutics Inc

IOVA
2.530USD
+0.170+7.20%
Close 02/06, 16:00ETQuotes delayed by 15 min
975.22MMarket Cap
LossP/E TTM

Iovance Biotherapeutics Inc

2.530
+0.170+7.20%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Iovance Biotherapeutics Inc

Currency: USD Updated: 2026-02-06

Key Insights

Iovance Biotherapeutics Inc's fundamentals are relatively healthy, with an industry-leading ESG disclosure.and its growth potential is high.Its valuation is considered fairly valued, ranking 94 out of 392 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Buy, with the highest price target at 8.40.In the medium term, the stock price is expected to remain stable.Despite an average stock market performance over the past month, the company shows strong fundamentals and technicals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Iovance Biotherapeutics Inc's Score

Industry at a Glance

Industry Ranking
94 / 392
Overall Ranking
221 / 4521
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Media Coverage

Last 24 hours
Coverage Level

Very Low
Very High
Neutral

Iovance Biotherapeutics Inc Highlights

StrengthsRisks
Iovance Biotherapeutics, Inc. is a commercial biotechnology company. It is focused on developing and delivering novel polyclonal tumor infiltrating lymphocyte (TIL) therapies for patients with cancer. Its product, Amtagvi, is a tumor-derived autologous T cell immunotherapy indicated for the treatment of adult patients with unresectable or metastatic melanoma previously treated with a PD-1 blocking antibody, and if BRAF V600 mutation positive, a BRAF inhibitor with or without a MEK inhibitor. It is marketing Proleukin (aldesleukin), an interleukin-2 (IL-2) product used in the Amtagvi treatment regimen and in other applications. Amtagvi and Proleukin are part of a treatment regimen that includes lymphodepletion. Its development pipeline includes multicenter trials of TIL cell therapies in additional treatment settings and indications for solid tumor cancers. It also develops therapies, such as genetically modified TIL cell therapy and cytokines for use in the TIL cell therapy regimen.
Overvalued
The company’s latest PE is -2.13, at a high 3-year percentile range.
Institutional Selling
The latest institutional holdings are 245.96M shares, decreasing 23.82% quarter-over-quarter.
Held by CI Select Canadian Equity Fund
Star Investor CI Select Canadian Equity Fund holds 784.00 shares of this stock.
Lower Market Activity
The company has less investor interest, with a 20-day turnover ratio of 0.42.

Analyst Rating

Based on 12 analysts
Buy
Current Rating
8.400
Target Price
+244.26%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Financial Health

Currency: USD Updated: 2026-02-06

The current financial score of Iovance Biotherapeutics Inc is 7.78, ranking 78 out of 392 in the Biotechnology & Medical Research industry. Its financial status is stable, and its operating efficiency is high. Its latest quarterly revenue reached 67.45M, representing a year-over-year increase of 15.20%, while its net profit experienced a year-over-year increase of 9.23%.

Score

Industry at a Glance

Previous score
7.78
Change
0

Financials

6.97

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

7.61

Operational Efficiency

10.00

Growth Potential

7.13

Shareholder Returns

7.20

Iovance Biotherapeutics Inc's Company Valuation

Currency: USD Updated: 2026-02-06

The current valuation score of Iovance Biotherapeutics Inc is 7.46, ranking 119 out of 392 in the Biotechnology & Medical Research industry. Its current P/E ratio is -2.13, which is -35.98% below the recent high of -1.36 and -335.05% above the recent low of -9.25.

Score

Industry at a Glance

Previous score
7.46
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 94/392
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2026-02-06

The current earnings forecast score of Iovance Biotherapeutics Inc is 7.17, ranking 308 out of 392 in the Biotechnology & Medical Research industry. The average price target is 9.00, with a high of 17.00 and a low of 1.50.

Score

Industry at a Glance

Previous score
7.17
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 12 analysts
Buy
Current Rating
8.400
Target Price
+244.26%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

542
Total
6
Median
6
Average
Company name
Ratings
Analysts
Iovance Biotherapeutics Inc
IOVA
12
CRISPR Therapeutics AG
CRSP
29
argenx SE
ARGX
26
IQVIA Holdings Inc
IQV
26
Beigene Ltd
ONC
24
Intellia Therapeutics Inc
NTLA
24
1
2
3
...
109

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2026-02-06

The current price momentum score of Iovance Biotherapeutics Inc is 6.48, ranking 235 out of 392 in the Biotechnology & Medical Research industry. Currently, the stock price is trading between the resistance level at 2.97 and the support level at 2.15, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
6.16
Change
0.32

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(2)
Neutral(4)
Buy(1)
Indicators
Value
Direction
MACD(12,26,9)
-0.053
Neutral
RSI(14)
49.216
Neutral
STOCH(KDJ)(9,3,3)
26.167
Neutral
ATR(14)
0.227
Low Volatility
CCI(14)
-58.892
Neutral
Williams %R
63.291
Sell
TRIX(12,20)
0.134
Sell
StochRSI(14)
67.019
Buy
Moving Average
Sell(2)
Neutral(0)
Buy(4)
Indicators
Value
Direction
MA5
2.516
Buy
MA10
2.638
Sell
MA20
2.541
Sell
MA50
2.497
Buy
MA100
2.354
Buy
MA200
2.348
Buy

Institutional Confidence

Currency: USD Updated: 2026-02-06

The current institutional shareholding score of Iovance Biotherapeutics Inc is 5.00, ranking 139 out of 392 in the Biotechnology & Medical Research industry. The latest institutional shareholding proportion is 61.96%, representing a quarter-over-quarter decrease of 1.26%. The largest institutional shareholder is The Vanguard, holding a total of 27.12M shares, representing 6.83% of shares outstanding, with 17.73% decrease in holdings.

Score

Industry at a Glance

Previous score
5.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
MHR Fund Management LLC
28.97M
--
Quogue Capital L.L.C.
28.07M
--
The Vanguard Group, Inc.
Star Investors
24.01M
-4.07%
BlackRock Institutional Trust Company, N.A.
21.68M
+11.17%
State Street Investment Management (US)
13.31M
+34.57%
Invenomic Capital Management LP
10.54M
+27.09%
Long Focus Capital Management LLC
9.12M
-22.87%
Palo Alto Investors LP
7.62M
+122.15%
Geode Capital Management, L.L.C.
6.87M
+10.97%
BofA Global Research (US)
6.28M
+55.83%
1
2

Risk Assessment

Currency: USD Updated: 2026-02-06

The U.S. Dollar Index is currently in a neutral state, which has a neutral effect on the Biotechnology & Medical Research domestic-focused industry. The Dollar Index (DXY) measures the value of the U.S. dollar against a basket of major currencies, including the euro, yen, pound sterling, Canadian dollar, Swedish krona, and Swiss franc. The current risk assessment score of Iovance Biotherapeutics Inc is 4.11, ranking 106 out of 392 in the Biotechnology & Medical Research industry. The company's beta value is 0.79. This indicates that the stock tends to underperform the index during upward trending markets but experiences smaller declines during downward trending markets. with an industry-leading ESG disclosure.

Score

Industry at a Glance

Previous score
4.11
Change
0
Beta vs S&P 500 index
0.78
VaR
+7.16%
240-Day Maximum Drawdown
+70.09%
240-Day Volatility
+116.63%

Return

Best Daily Return
60 days
+12.10%
120 days
+27.62%
5 years
+31.48%
Worst Daily Return
60 days
-9.72%
120 days
-9.72%
5 years
-53.57%
Sharpe Ratio
60 days
+0.88
120 days
+0.48
5 years
-0.12

Risk Assessment

Maximum Drawdown
240 days
+70.09%
3 years
+90.50%
5 years
+94.79%
Return-to-Drawdown Ratio
240 days
-0.78
3 years
-0.20
5 years
-0.19
Skewness
240 days
-0.40
3 years
+0.44
5 years
-0.55

Volatility

Realised Volatility
240 days
+116.63%
5 years
+92.45%
Standardised True Range
240 days
+8.88%
5 years
+26.76%
Downside Risk-Adjusted Return
120 days
+104.50%
240 days
+104.50%
Maximum Daily Upside Volatility
60 days
+62.55%
Maximum Daily Downside Volatility
60 days
+44.17%

Liquidity

Average Turnover Rate
60 days
+5.20%
120 days
+4.52%
5 years
--
Turnover Deviation
20 days
+42.35%
60 days
+64.34%
120 days
+42.93%

Peer Comparison

Biotechnology & Medical Research
Iovance Biotherapeutics Inc
Iovance Biotherapeutics Inc
IOVA
6.71 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Alkermes Plc
Alkermes Plc
ALKS
8.60 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Ascendis Pharma A/S
Ascendis Pharma A/S
ASND
8.53 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Ionis Pharmaceuticals Inc
Ionis Pharmaceuticals Inc
IONS
8.38 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
IQVIA Holdings Inc
IQVIA Holdings Inc
IQV
8.37 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
BioCryst Pharmaceuticals Inc
BioCryst Pharmaceuticals Inc
BCRX
8.17 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
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