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Iovance Biotherapeutics Inc

IOVA
2.140USD
+0.170+8.63%
Market hours ETQuotes delayed by 15 min
731.71MMarket Cap
LossP/E TTM

Iovance Biotherapeutics Inc

2.140
+0.170+8.63%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Iovance Biotherapeutics Inc

Currency: USD Updated: 2025-10-31

Key Insights

The company's fundamentals are relatively healthy. Its valuation is considered fairly valued,and institutional recognition is very high. Over the past 30 days, multiple analysts have rated the company as a Buy. Despite a weak stock market performance, the company shows strong fundamentals. The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Iovance Biotherapeutics Inc's Score

Industry at a Glance

Industry Ranking
146 / 407
Overall Ranking
254 / 4618
Industry
Biotechnology & Medical Research

Support & Resistance

No Data

Score Analysis

Current score
Previous score

Analyst Rating

Based on 12 analysts
Buy
Current Rating
8.000
Target Price
+306.09%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Iovance Biotherapeutics Inc Highlights

StrengthsRisks
Iovance Biotherapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company develops and delivers tumor infiltrating lymphocyte (TIL), therapies for patients with solid tumor cancers. Its lead product candidate, Amtagvi (lifileucel), is a tumor-derived autologous T cell immunotherapy indicated for the treatment of adult patients with unresectable or metastatic melanoma previously treated with a PD-1 blocking antibody, and if BRAF V600 mutation positive, a BRAF inhibitor with or without a MEK inhibitor. The Company also marketing Proleukin (aldesleukin), aninterleukin-2, or IL-2, product used in the Amtagvi treatment regimen. Its development pipeline includes multicenter trials of TIL cell therapies in additional treatment settings for solid tumor cancers. Amtagvi and Proleukin are part of a treatment regimen that also includes lymphodepletion. The Company is also developing next generation therapies using TIL, such as genetically modified TIL cell therapy.
Overvalued
The company’s latest PE is -1.62, at a high 3-year percentile range.
Institutional Selling
The latest institutional holdings are 251.63M shares, decreasing 17.24% quarter-over-quarter.
Held by Invesco
Star Investor Invesco holds 505.49K shares of this stock.
Lower Market Activity
The company has less investor interest, with a 20-day turnover ratio of 0.42.

Financial Health

Currency: USD Updated: 2025-10-31

The company's current financial score is 7.34, which is higher than the Biotechnology & Medical Research industry's average of 6.92. Its financial status is stable, and its operating efficiency is high. Its latest quarterly revenue reached 59.95M, representing a year-over-year increase of 92.73%, while its net profit experienced a year-over-year increase of 14.99%.

Score

Industry at a Glance

Previous score
7.34
Change
0

Financials

6.30

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
No Data

Quality of Earnings

7.22

Operational Efficiency

10.00

Growth Potential

5.94

Shareholder Returns

7.23

Iovance Biotherapeutics Inc's Company Valuation

Currency: USD Updated: 2025-10-31

The company’s current valuation score is 7.46, which is higher than the Biotechnology & Medical Research industry's average of 7.05. Its current P/E ratio is -1.62, which is -16.07% below the recent high of -1.36 and -470.30% above the recent low of -9.25.

Score

Industry at a Glance

Previous score
7.46
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 146/407
No Data

Earnings Forecast

Currency: USD Updated: 2025-10-31

The company’s current earnings forecast score is 7.17, which is lower than the Biotechnology & Medical Research industry's average of 8.01. The average price target for Iovance Biotherapeutics Inc is 7.00, with a high of 20.00 and a low of 1.00.

Score

Industry at a Glance

Previous score
7.17
Change
0

Support & Resistance

No Data

Analyst Rating

Based on 12 analysts
Buy
Current Rating
8.000
Target Price
+306.09%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

521
Total
5
Median
6
Average
Company name
Ratings
Analysts
Iovance Biotherapeutics Inc
IOVA
12
CRISPR Therapeutics AG
CRSP
30
Ionis Pharmaceuticals Inc
IONS
25
argenx SE
ARGX
25
Intellia Therapeutics Inc
NTLA
25
IQVIA Holdings Inc
IQV
25
1
2
3
...
104

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
No Data

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2025-10-31

The company’s current price momentum score is 5.59, which is lower than the Biotechnology & Medical Research industry's average of 6.66. Sideways: Currently, the stock price is trading between the resistance level at 2.28 and the support level at 1.80, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
5.52
Change
0.07

Support & Resistance

No Data

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(3)
Neutral(1)
Buy(0)
Indicators
Value
Direction
MACD(12,26,9)
-0.050
Sell
RSI(14)
39.767
Neutral
STOCH(KDJ)(9,3,3)
11.120
Oversold
ATR(14)
0.133
High Vlolatility
CCI(14)
-167.550
Sell
Williams %R
91.667
Oversold
TRIX(12,20)
-0.146
Sell
StochRSI(14)
7.247
Oversold
Moving Average
Sell(5)
Neutral(0)
Buy(1)
Indicators
Value
Direction
MA5
2.084
Buy
MA10
2.160
Sell
MA20
2.173
Sell
MA50
2.232
Sell
MA100
2.270
Sell
MA200
3.018
Sell

Institutional Confidence

Currency: USD Updated: 2025-10-31

The company’s current institutional recognition score is 5.00, which is lower than the Biotechnology & Medical Research industry's average of 5.21. The latest institutional shareholding proportion is 69.54%, representing a quarter-over-quarter decrease of 14.14%. The largest institutional shareholder is The Vanguard, holding a total of 25.03M shares, representing 6.92% of shares outstanding, with 23.30% decrease in holdings.

Score

Industry at a Glance

Previous score
5.00
Change
0

Institutional Shareholding

No Data

Shareholder Activity

Name
Shares Held
Chg %
MHR Fund Management LLC
28.97M
+18.63%
Quogue Capital L.L.C.
28.07M
--
The Vanguard Group, Inc.
Star Investors
25.03M
-9.74%
BlackRock Institutional Trust Company, N.A.
19.50M
-5.02%
Long Focus Capital Management LLC
11.82M
+27.78%
State Street Investment Management (US)
9.89M
-10.42%
Millennium Management LLC
9.33M
+5793.16%
Invenomic Capital Management LP
8.29M
+51.09%
Two Sigma Investments, LP
7.01M
+1666.83%
Geode Capital Management, L.L.C.
6.19M
+3.70%
1
2

Risk Assessment

Currency: USD Updated: 2025-10-31

The company’s current risk assessment score is 2.60, which is lower than the Biotechnology & Medical Research industry's average of 3.47. The company's beta value is 0.86. This indicates that the stock tends to underperform the index during upward trending markets but experiences smaller declines during downward trending markets.

Score

Industry at a Glance

Previous score
2.60
Change
0
Beta vs S&P 500 index
0.87
VaR
+7.12%
240-Day Maximum Drawdown
+82.34%
240-Day Volatility
+109.95%

Return

Best Daily Return
60 days
+13.20%
120 days
+26.84%
5 years
+31.48%
Worst Daily Return
60 days
-20.08%
120 days
-20.08%
5 years
-53.57%
Sharpe Ratio
60 days
-0.91
120 days
+0.74
5 years
-0.28

Risk Assessment

Maximum Drawdown
240 days
+82.34%
3 years
+90.50%
5 years
+96.84%
Return-to-Drawdown Ratio
240 days
-0.94
3 years
-0.26
5 years
-0.20
Skewness
240 days
-0.82
3 years
+0.33
5 years
-0.68

Volatility

Realised Volatility
240 days
+109.95%
5 years
+91.24%
Standardised True Range
240 days
+14.34%
5 years
+40.64%
Downside Risk-Adjusted Return
120 days
+142.61%
240 days
+142.61%
Maximum Daily Upside Volatility
60 days
+68.54%
Maximum Daily Downside Volatility
60 days
+67.79%

Liquidity

Average Turnover Rate
60 days
+5.20%
120 days
+4.52%
5 years
--
Turnover Deviation
20 days
+42.35%
60 days
+64.34%
120 days
+42.93%

Peer Comparison

Biotechnology & Medical Research
Iovance Biotherapeutics Inc
Iovance Biotherapeutics Inc
IOVA
6.27 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Zymeworks Inc
Zymeworks Inc
ZYME
8.55 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
NewAmsterdam Pharma Company NV
NewAmsterdam Pharma Company NV
NAMS
8.53 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Insmed Inc
Insmed Inc
INSM
8.52 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
IQVIA Holdings Inc
IQVIA Holdings Inc
IQV
8.52 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
BioCryst Pharmaceuticals Inc
BioCryst Pharmaceuticals Inc
BCRX
8.50 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
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