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Crinetics Pharmaceuticals Inc

CRNX
48.255USD
-0.455-0.93%
Market hours ETQuotes delayed by 15 min
4.56BMarket Cap
LossP/E TTM

Crinetics Pharmaceuticals Inc

48.255
-0.455-0.93%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Crinetics Pharmaceuticals Inc

Currency: USD Updated: 2025-12-24

Key Insights

Crinetics Pharmaceuticals Inc's fundamentals are relatively healthy, and its growth potential is high.Its valuation is considered fairly valued, ranking 32/404 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Buy, with the highest price target at 80.14.In the medium term, the stock price is expected to trend up.The company has been performing well in the stock market over the past month, which is supported by its strong fundamentals and technicals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Crinetics Pharmaceuticals Inc's Score

Industry at a Glance

Industry Ranking
32 / 404
Overall Ranking
108 / 4562
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Analyst Rating

Based on 16 analysts
Buy
Current Rating
80.143
Target Price
+69.08%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Crinetics Pharmaceuticals Inc Highlights

StrengthsRisks
Crinetics Pharmaceuticals, Inc. is a clinical-stage pharmaceutical company focused on the discovery, development and commercialization of therapeutics for rare endocrine diseases and endocrine-related tumors. Its lead development candidate, PALSONIFY (paltusotine), is the first investigational once-daily, oral, selective somatostatin receptor type 2 (SST2) nonpeptide agonist that is in clinical development for acromegaly and carcinoid syndrome associated with neuroendocrine tumors. Its second product candidate is Atumelnant, which is in clinical development for congenital adrenal hyperplasia (CAH) and patients with either Cushing's disease or Ectopic ACTH Syndrome (EAS). Its drug candidates are orally delivered, small molecule new chemical entities resulting from in-house drug discovery efforts, including other programs addressing a variety of endocrine conditions such as hyperparathyroidism, polycystic kidney disease, Graves' disease, thyroid eye disease, diabetes and obesity.
Growing
The company is in a growing phase, with the latest annual income totaling USD 1.04M.
High Profit Growth
The company's net income leads the industry, with the latest annual income totaling USD 1.04M.
Fairly Valued
The company’s latest PE is -10.76, at a medium 3-year percentile range.
Institutional Buying
The latest institutional holdings are 110.25M shares, increasing 0.01% quarter-over-quarter.
Held by CI Select Canadian Equity Fund
Star Investor CI Select Canadian Equity Fund holds 388.00 shares of this stock.
Higher Market Activity
The company has more investor interest, with a 20-day turnover ratio of 0.06.

Financial Health

Currency: USD Updated: 2025-12-24

The current financial score of Crinetics Pharmaceuticals Inc is 7.11, ranking 163/404 in the Biotechnology & Medical Research industry. Its financial status is stable, and its operating efficiency is low.

Score

Industry at a Glance

Previous score
7.11
Change
0

Financials

7.07

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

7.89

Operational Efficiency

3.09

Growth Potential

10.00

Shareholder Returns

7.48

Crinetics Pharmaceuticals Inc's Company Valuation

Currency: USD Updated: 2025-12-24

The current valuation score of Crinetics Pharmaceuticals Inc is 6.47, ranking 280/404 in the Biotechnology & Medical Research industry. Its current P/E ratio is -10.76, which is -56.48% below the recent high of -4.68 and -52.06% above the recent low of -16.36.

Score

Industry at a Glance

Previous score
6.47
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 32/404
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2025-12-24

The current earnings forecast score of Crinetics Pharmaceuticals Inc is 8.38, ranking 136/404 in the Biotechnology & Medical Research industry. The average price target for Crinetics Pharmaceuticals Inc is 83.00, with a high of 108.00 and a low of 45.00.

Score

Industry at a Glance

Previous score
8.38
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 16 analysts
Buy
Current Rating
80.143
Target Price
+69.08%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

534
Total
6
Median
6
Average
Company name
Ratings
Analysts
Crinetics Pharmaceuticals Inc
CRNX
16
CRISPR Therapeutics AG
CRSP
30
argenx SE
ARGX
25
Intellia Therapeutics Inc
NTLA
25
IQVIA Holdings Inc
IQV
25
Ionis Pharmaceuticals Inc
IONS
24
1
2
3
...
107

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2025-12-24

The current price momentum score of Crinetics Pharmaceuticals Inc is 8.87, ranking 83/404 in the Biotechnology & Medical Research industry. Currently, the stock price is trading between the resistance level at 52.11 and the support level at 44.17, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
9.15
Change
-0.28

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(1)
Neutral(4)
Buy(1)
Indicators
Value
Direction
MACD(12,26,9)
-0.210
Neutral
RSI(14)
57.617
Neutral
STOCH(KDJ)(9,3,3)
69.974
Neutral
ATR(14)
2.166
High Vlolatility
CCI(14)
44.092
Neutral
Williams %R
28.589
Buy
TRIX(12,20)
0.449
Sell
StochRSI(14)
83.780
Overbought
Moving Average
Sell(1)
Neutral(0)
Buy(5)
Indicators
Value
Direction
MA5
47.994
Buy
MA10
48.539
Sell
MA20
47.584
Buy
MA50
44.562
Buy
MA100
39.757
Buy
MA200
35.536
Buy

Institutional Confidence

Currency: USD Updated: 2025-12-24

The current institutional shareholding score of Crinetics Pharmaceuticals Inc is 10.00, ranking 1/404 in the Biotechnology & Medical Research industry. The latest institutional shareholding proportion is 122.53%, representing a quarter-over-quarter decrease of 3.11%. The largest institutional shareholder is The Vanguard, holding a total of 9.15M shares, representing 9.64% of shares outstanding, with 2.78% decrease in holdings.

Score

Industry at a Glance

Previous score
10.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
Fidelity Management & Research Company LLC
12.42M
+0.79%
The Vanguard Group, Inc.
Star Investors
9.24M
-0.60%
Wellington Management Company, LLP
5.81M
-15.73%
BlackRock Institutional Trust Company, N.A.
6.50M
-4.05%
Driehaus Capital Management, LLC
6.40M
+2.57%
Farallon Capital Management, L.L.C.
5.63M
+21.07%
T. Rowe Price Associates, Inc.
Star Investors
5.49M
+9.40%
EcoR1 Capital, LLC
4.29M
--
Janus Henderson Investors
3.41M
-0.41%
Paradigm BioCapital Advisors LP
2.34M
+20.42%
1
2

Risk Assessment

Currency: USD Updated: 2025-12-24

The current risk assessment score of Crinetics Pharmaceuticals Inc is 5.18, ranking 58/404 in the Biotechnology & Medical Research industry. The company's beta value is 0.19. This indicates that the stock tends to underperform the index during upward trending markets but experiences smaller declines during downward trending markets.

Score

Industry at a Glance

Previous score
5.18
Change
0
Beta vs S&P 500 index
0.19
VaR
+5.36%
240-Day Maximum Drawdown
+37.03%
240-Day Volatility
+56.22%

Return

Best Daily Return
60 days
+8.17%
120 days
+27.92%
5 years
+63.31%
Worst Daily Return
60 days
-8.02%
120 days
-8.02%
5 years
-16.31%
Sharpe Ratio
60 days
+1.24
120 days
+1.92
5 years
+0.65

Risk Assessment

Maximum Drawdown
240 days
+37.03%
3 years
+57.88%
5 years
+57.88%
Return-to-Drawdown Ratio
240 days
+0.54
3 years
+0.86
5 years
+0.67
Skewness
240 days
+1.24
3 years
+5.65
5 years
+3.79

Volatility

Realised Volatility
240 days
+56.22%
5 years
+62.63%
Standardised True Range
240 days
+3.62%
5 years
+3.11%
Downside Risk-Adjusted Return
120 days
+446.53%
240 days
+446.53%
Maximum Daily Upside Volatility
60 days
+37.55%
Maximum Daily Downside Volatility
60 days
+32.77%

Liquidity

Average Turnover Rate
60 days
+0.90%
120 days
+0.98%
5 years
--
Turnover Deviation
20 days
+6.03%
60 days
-14.97%
120 days
-7.46%

Peer Comparison

Biotechnology & Medical Research
Crinetics Pharmaceuticals Inc
Crinetics Pharmaceuticals Inc
CRNX
7.72 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Amicus Therapeutics Inc
Amicus Therapeutics Inc
FOLD
8.82 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
IQVIA Holdings Inc
IQVIA Holdings Inc
IQV
8.67 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Dynavax Technologies Corp
Dynavax Technologies Corp
DVAX
8.56 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
BioCryst Pharmaceuticals Inc
BioCryst Pharmaceuticals Inc
BCRX
8.50 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Krystal Biotech Inc
Krystal Biotech Inc
KRYS
8.46 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
View more

FAQs

How does TradingKey generate the Stock Score of Crinetics Pharmaceuticals Inc?

The TradingKey Stock Score provides a comprehensive assessment of Crinetics Pharmaceuticals Inc based on 34 indicators derived from over 100 underlying data points.
These indicators are categorised into six key dimensions: financial health, company profile, earnings forecasts, price momentum, institutional confidence, and risk assessment, collectively providing investors with a thorough analysis of Crinetics Pharmaceuticals Inc’s performance and outlook.

How do we generate the financial health score of Crinetics Pharmaceuticals Inc?

To generate the financial health score of Crinetics Pharmaceuticals Inc, we analyse various key financial indicators across several core dimensions, including financial fundamentals, earnings quality, operational efficiency, growth potential, and shareholder returns.
By integrating these comprehensive data, the financial health score not only reflects Crinetics Pharmaceuticals Inc's overall stability, operational efficiency, and growth potential but also captures the investment returns delivered to shareholders. This score aims to support rational decision-making for investors and other stakeholders. A higher score indicates a better financial health of Crinetics Pharmaceuticals Inc.

How do we generate the company valuation score of Crinetics Pharmaceuticals Inc?

To generate the company valuation score of Crinetics Pharmaceuticals Inc, we use several key financial ratios, including P/E, P/B, P/S, and P/CF. These metrics compare Crinetics Pharmaceuticals Inc’s market value to its earnings, assets, sales, and cash flow, serving as core indicators for assessing company value.
By analysing these ratios in an all-round manner, the valuation score reflects not only the market’s current perception of Crinetics Pharmaceuticals Inc’s value but also its future profitability and growth potential, thereby supporting more informed investment decisions. A higher score indicates a fairer valuation of Crinetics Pharmaceuticals Inc.

How do we generate the earnings forecast score of Crinetics Pharmaceuticals Inc?

To calculate the earnings forecast score of Crinetics Pharmaceuticals Inc, we consider various key indicators such as analyst ratings, financial forecasts, support and resistance levels, and peer comparisons:
Current ratings and price targets directly reflect analysts’ expectations, while the upside space indicates their views on the stock’s growth potential.
Financial metrics like earnings per share (EPS), revenue, net income, and earnings before interest and taxes (EBIT) are core measures for assessing profitability.
By analysing the high, median, and low ranges of the target price, we can identify price trends and determine key support and resistance levels.
Comparing these indicators against peers provides context for the stock’s performance and helps anchor more realistic expectations.
These factors together form a comprehensive earnings forecast score that accurately reflects the stock’s expected financial performance and growth potential. A higher score suggests that analysts have a more optimistic outlook on Crinetics Pharmaceuticals Inc’s future.

How do we generate the price momentum score of Crinetics Pharmaceuticals Inc?

When generating the price momentum score for Crinetics Pharmaceuticals Inc, we examine momentum indicators including support and resistance levels as well as volume metrics.
Support levels represent price points where buying interest is strong enough to prevent further declines, while resistance levels indicate prices where selling pressure may hinder upward movement. By analysing typical price volume alongside total volume, we assess overall market activity and liquidity. These indicators help identify price trends and potential shifts, enabling more accurate predictions of future earnings.
This comprehensive approach can reflect market sentiment and enable rational forecasts of Crinetics Pharmaceuticals Inc’s prices. A higher score indicates a more stable short-term price trend for Crinetics Pharmaceuticals Inc.

How do we generate the institutional confidence score of Crinetics Pharmaceuticals Inc?

To generate the institutional confidence score of Crinetics Pharmaceuticals Inc, we analyse both the proportion of shares held by institutions and the number of shares they own. A higher institutional ownership percentage indicates strong confidence of professional investors, which is generally a positive signal about Crinetics Pharmaceuticals Inc’s potential. By examining the number of shares held, we gain deeper insight into institutions’ commitment and attitude toward the stock, as institutional investors typically conduct thorough analysis before making investment decisions. Understanding institutional confidence helps us refine earnings forecasts and provides a more reliable perspective on the company’s future performance and market stability. A higher score indicates greater institutional endorsement of Crinetics Pharmaceuticals Inc.

How do we generate the risk management score of Crinetics Pharmaceuticals Inc?

To assess the risk management score of Crinetics Pharmaceuticals Inc, we examine multiple key indicators related to returns, risk, volatility, and liquidity.
The highest and lowest daily returns reflect the potential size of gains and losses, while the Sharpe ratio measures risk-adjusted return performance. On the risk side, we analyse maximum drawdown and the return-to-drawdown ratio to identify extreme loss scenarios. Skewness helps assess the distribution of returns and whether performance may be biased. Volatility indicators—such as realised volatility and standardised true range—reveal price fluctuations. Downside risk-adjusted returns provide insight into potential losses and gains. Lastly, liquidity metrics like average turnover rate and turnover deviation indicate how actively the stock is traded.
These indicators together provide a multi-dimensional understanding of Crinetics Pharmaceuticals Inc’s risk-return profile, serving as core factors of the risk management score. A higher score indicates lower risk on the side of Crinetics Pharmaceuticals Inc.
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